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Items: 1 to 20 of 497

1.
Cell fixation improves performance of in situ crosslinking mass spectrometry while preserving cellular ultrastructure
Andrew R. M. Michael, Bruno C. Amaral, Kallie L. Ball, Kristen H. Eiriksson, David C. Schriemer
Nat Commun. 2024; 15: 8537. Published online 2024 Oct 2. doi: 10.1038/s41467-024-52844-y
PMCID:
PMC11447256
AbstractArticlePDF–2.8M
2.
The roles of NADPH and isocitrate dehydrogenase in cochlear mitochondrial antioxidant defense and aging
Karessa White, Shinichi Someya
Hear Res. Author manuscript; available in PMC 2024 Oct 2.
Published in final edited form as: Hear Res. 2023 Jan; 427: 108659. Published online 2022 Nov 24. doi: 10.1016/j.heares.2022.108659
PMCID:
PMC11446251
AbstractArticlePDF–944K
3.
Differential isocitrate dehydrogenase 1 and isocitrate dehydrogenase 2 mutation-related landscape in intrahepatic cholangiocarcinoma
Shuaishuai Xu, Linping Cao, Ruyin Chen, Chanqi Ye, Qiong Li, Qi Jiang, Feifei Yan, Mingyu Wan, Xiaochen Zhang, Jian Ruan
Oncologist. 2024 Aug; 29(8): e1061–e1072. Published online 2024 Jun 6. doi: 10.1093/oncolo/oyae132
PMCID:
PMC11299938
AbstractArticlePDF–28M
4.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
5.
Analysis of IDH1 and IDH2 mutations in Japanese glioma patients
Yukihiko Sonoda, Toshihiro Kumabe, Taigen Nakamura, Ryuta Saito, Masayuki Kanamori, Yoji Yamashita, Hiroyoshi Suzuki, Teiji Tominaga
Cancer Sci. 2009 Oct; 100(10): 1996–1998. Published online 2009 Sep 14. doi: 10.1111/j.1349-7006.2009.01270.x
PMCID:
PMC11159618
AbstractArticlePDF–531K
6.
The interplay mechanism between IDH mutation, MGMT-promoter methylation, and PRMT5 activity in the progression of grade 4 astrocytoma: unraveling the complex triad theory
MAHER KURDI, ALAA ALKHOTANI, ABDULRAHMAN SABBAGH, EYAD FAIZO, AHMED I. LARY, AHMED K. BAMAGA, MAJID ALMANSOURI, BADR HAFIZ, THAMER ALSHARIF, SALEH BAEESA
Oncol Res. 2024; 32(6): 1037–1045. Published online 2024 May 23. doi: 10.32604/or.2024.051112
PMCID:
PMC11136683
AbstractArticlePDF–3.0M
7.
IDH1 mutation produces R-2-hydroxyglutarate (R-2HG) and induces mir-182-5p expression to regulate cell cycle and tumor formation in glioma
Haiting Zhao, Li Meng, Peng Du, Xinbin Liao, Xin Mo, Mengqi Gong, Jiaxin Chen, Yiwei Liao
Biol Res. 2024; 57: 30. Published online 2024 May 17. doi: 10.1186/s40659-024-00512-2
PMCID:
PMC11100189
AbstractArticlePDF–16M
8.
DNA damage in IDH-mutant gliomas: mechanisms and clinical implications
Diana D. Shi, Soummitra Anand, Kalil G. Abdullah, Samuel K. McBrayer
J Neurooncol. Author manuscript; available in PMC 2024 May 1.
Published in final edited form as: J Neurooncol. 2023 May; 162(3): 515–523. Published online 2022 Nov 9. doi: 10.1007/s11060-022-04172-8
PMCID:
PMC10956168
AbstractArticlePDF–775K
9.
The Epigenetic Evolution of Glioma Is Determined by the IDH1 Mutation Status and Treatment Regimen
Tathiane M. Malta, Thais S. Sabedot, Natalia S. Morosini, Indrani Datta, Luciano Garofano, Wies Vallentgoed, Frederick S. Varn, Kenneth Aldape, Fulvio D'Angelo, Spyridon Bakas, Jill S. Barnholtz-Sloan, Hui K. Gan, Mohammad Hasanain, Ann-Christin Hau, Kevin C. Johnson, Simona Cazacu, Ana C. deCarvalho, Mustafa Khasraw, Emre Kocakavuk, Mathilde C.M. Kouwenhoven, Simona Migliozzi, Simone P. Niclou, Johanna M. Niers, D. Ryan Ormond, Sun Ha Paek, Guido Reifenberger, Peter A. Sillevis Smitt, Marion Smits, Lucy F. Stead, Martin J. van den Bent, Erwin G. Van Meir, Annemiek Walenkamp, Tobias Weiss, Michael Weller, Bart A. Westerman, Bauke Ylstra, Pieter Wesseling, Anna Lasorella, Pim J. French, Laila M. Poisson, Consortium The GLASS , Roel G.W. Verhaak, Antonio Iavarone, Houtan Noushmehr
Cancer Res. 2024 Mar 4; 84(5): 741–756. Published online 2023 Dec 20. doi: 10.1158/0008-5472.CAN-23-2093
PMCID:
PMC10911804
AbstractArticlePDF–17M
10.
Cognitive functioning is prognostic in patients with IDH1-wild type and MGMT-unmethylated high-grade gliomas
Uroš Smrdel, Andreja Cirila Škufca Smrdel, Anja Podlesek, Marija Skoblar Vidmar, Gregor Kos, Jana Markovic, Jana Jereb, Jana Knific, Tina Rus
Croat Med J. 2023 Dec; 64(6): 383–390. doi: 10.3325/cmj.2023.64.383
PMCID:
PMC10797236
AbstractArticlePDF–373K
11.
Improved prognostic stratification of patients with isocitrate dehydrogenase-mutant astrocytoma
Michael Weller, Jörg Felsberg, Bettina Hentschel, Dorothee Gramatzki, Nadezhda Kubon, Marietta Wolter, Matthias Reusche, Patrick Roth, Dietmar Krex, Ulrich Herrlinger, Manfred Westphal, Joerg C. Tonn, Luca Regli, Claude-Alain Maurage, Andreas von Deimling, Torsten Pietsch, Emilie Le Rhun, Guido Reifenberger
Acta Neuropathol. 2024; 147(1): 11. Published online 2024 Jan 6. doi: 10.1007/s00401-023-02662-1
PMCID:
PMC10771615
AbstractArticlePDF–2.0M
12.
Genetic Polymorphism Study of IDH 1/2 and TET2 Genes in Acute Myeloid leukemia Patients
Manal Atef, Nevine Fawzy Shafik, Nagwa H.A. Hassan, Rasha Mahmoud Allam, Yomna Mohamed EL-Meligui, Hisham Abdelaziz
Asian Pac J Cancer Prev. 2023; 24(9): 3169–3182. doi: 10.31557/APJCP.2023.24.9.3169
PMCID:
PMC10762743
AbstractArticlePDF–762K
13.
IDH1R132H mutation increases radiotherapy efficacy and a 4-gene radiotherapy-related signature of WHO grade 4 gliomas
Xuetao Han, Huandi Zhou, Wei Sun, Liubing Hou, Yanqiang Wang, Hong Wang, Zhongqiang Lv, Xiaoying Xue
Sci Rep. 2023; 13: 19659. Published online 2023 Nov 11. doi: 10.1038/s41598-023-46335-1
PMCID:
PMC10640646
AbstractArticlePDF–5.3M
14.
IDH1 mutation impairs antiviral response and potentiates oncolytic virotherapy in glioma
Xueqin Chen, Jun Liu, Yuqin Li, Yuequan Zeng, Fang Wang, Zexiong Cheng, Hao Duan, Guopeng Pan, Shangqi Yang, Yuling Chen, Qing Li, Xi Shen, Ying Li, Zixi Qin, Jiahong Chen, Youwei Huang, Xiangyu Wang, Yuli Lu, Minfeng Shu, Yubo Zhang, Guocai Wang, Kai Li, Xi Lin, Fan Xing, Haipeng Zhang
Nat Commun. 2023; 14: 6781. Published online 2023 Oct 25. doi: 10.1038/s41467-023-42545-3
PMCID:
PMC10600173
AbstractArticlePDF–11M
15.
Mutant IDH regulates glycogen metabolism from early cartilage development to malignant chondrosarcoma formation
Sinthu Pathmanapan, Raymond Poon, Tomasa Barrientos De Renshaw, Puviindran Nadesan, Makoto Nakagawa, Gireesh A. Seesankar, Adrian Kwan Ho Loe, Hongyuan H. Zhang, Joan J. Guinovart, Jordi Duran, Christopher B. Newgard, Jay S. Wunder, Benjamin A. Alman
Cell Rep. Author manuscript; available in PMC 2023 Oct 23.
Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112578. Published online 2023 Jun 1. doi: 10.1016/j.celrep.2023.112578
PMCID:
PMC10592452
AbstractArticlePDF–1.7M
16.
Diffusion tensor imaging‐based machine learning for IDH wild‐type glioblastoma stratification to reveal the biological underpinning of radiomic features
Zilong Wang, Fangzhan Guan, Wenchao Duan, Yu Guo, Dongling Pei, Yuning Qiu, Minkai Wang, Aoqi Xing, Zhongyi Liu, Bin Yu, Hongwei Zheng, Xianzhi Liu, Dongming Yan, Yuchen Ji, Jingliang Cheng, Jing Yan, Zhenyu Zhang
CNS Neurosci Ther. 2023 Nov; 29(11): 3339–3350. Published online 2023 May 24. doi: 10.1111/cns.14263
PMCID:
PMC10580329
AbstractArticlePDF–29M
17.
Mutant IDH1 Cooperates with ATRX Loss to Drive the Alternative Lengthening of Telomere Phenotype in Glioma
Joydeep Mukherjee, Tor-Christian Johannessen, Shigeo Ohba, Tracy T. Chow, Lindsey Jones, Ajay Pandita, Russell O. Pieper
Cancer Res. Author manuscript; available in PMC 2023 Oct 16.
Published in final edited form as: Cancer Res. 2018 Jun 1; 78(11): 2966–2977. Published online 2018 Mar 15. doi: 10.1158/0008-5472.CAN-17-2269
PMCID:
PMC10578296
AbstractArticlePDF–1.5M
18.
Isocitrate dehydrogenase 1 sustains a hybrid cytoplasmic–mitochondrial tricarboxylic acid cycle that can be targeted for therapeutic purposes in prostate cancer
Kevin Gonthier, Cindy Weidmann, Line Berthiaume, Cynthia Jobin, Aurélie Lacouture, Camille Lafront, Mario Harvey, Bertrand Neveu, Jérémy Loehr, Alain Bergeron, Yves Fradet, Louis Lacombe, Julie Riopel, Éva Latulippe, Chantal Atallah, Michael Shum, Jean‐Philippe Lambert, Frédéric Pouliot, Martin Pelletier, Étienne Audet‐Walsh
Mol Oncol. 2023 Oct; 17(10): 2109–2125. Published online 2023 Jul 19. doi: 10.1002/1878-0261.13441
PMCID:
PMC10552900
AbstractArticlePDF–1.0M
19.
Classification of IDH wild-type glioblastoma tumorspheres into low- and high-invasion groups based on their transcriptional program
Junseong Park, Jin-Kyoung Shim, Mirae Lee, Dokyeong Kim, Seon-Jin Yoon, Ju Hyung Moon, Eui Hyun Kim, Jeong-Yoon Park, Jong Hee Chang, Seok-Gu Kang
Br J Cancer. 2023 Oct 19; 129(7): 1061–1070. Published online 2023 Aug 9. doi: 10.1038/s41416-023-02391-y
PMCID:
PMC10539507
AbstractArticlePDF–5.1M
20.
磁共振酰胺质子转移模态的胶质瘤IDH基因分型识别：基于深度学习的Dual-Aware框架
楚 智钦, 屈 耀铭, 钟 涛, 梁 淑君, 温 志波, 张 煜
Nan Fang Yi Ke Da Xue Xue Bao. 2023 Aug 20; 43(8): 1379–1387. Chinese. doi: 10.12122/j.issn.1673-4254.2023.08.15
PMCID:
PMC10505564
AbstractArticlePDF–1.4M

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