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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108643632.

Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy

Yan Guo, Pan Xiang, Xiaojiao Sun, Wei Liu, Jiafeng Zhou, Bin Yin, Lin Hou, Boqin Qiang, Huiliang Li, Pengcheng Shu, Xiaozhong Peng

Signal Transduct Target Ther. 2024; 9: 32. Published online 2024 Feb 14. doi: 10.1038/s41392-024-01742-2

PMCID:: PMC10864363

Abstract Article PDF–9.9M

Select item 100428293.

Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity

Shuwen He, John P. Gillies, Juliana L. Zang, Carmen M. Córdoba-Beldad, Io Yamamoto, Yasuhiro Fujiwara, Julie Grantham, Morgan E. DeSantis, Hiroki Shibuya

Nat Commun. 2023; 14: 1715. Published online 2023 Mar 27. doi: 10.1038/s41467-023-37370-7

PMCID:: PMC10042829

Abstract Article PDF–4.3M

Select item 97754894.

Large-Scale Functional Assessment of Genes Involved in Rare Diseases with Intellectual Disabilities Unravels Unique Developmental and Behaviour Profiles in Mouse Models

Hamid Meziane, Marie-Christine Birling, Olivia Wendling, Sophie Leblanc, Aline Dubos, Mohammed Selloum, Guillaume Pavlovic, Tania Sorg, Vera M. Kalscheuer, Pierre Billuart, Frédéric Laumonnier, Jamel Chelly, Hans van Bokhoven, Yann Herault

Biomedicines. 2022 Dec; 10(12): 3148. Published online 2022 Dec 6. doi: 10.3390/biomedicines10123148

PMCID:: PMC9775489

Abstract Article PDF–2.8M

Select item 96876045.

A conditional null allele of Dync1h1 enables targeted analyses of dynein roles in neuronal length sensing

Agostina Di Pizio, Letizia Marvaldi, Marie-Christine Birling, Nataliya Okladnikov, Luc Dupuis, Mike Fainzilber, Ida Rishal

J Cell Sci. 2023 Mar 1; 136(5): jcs260220. Published online 2022 Oct 31. doi: 10.1242/jcs.260220

PMCID:: PMC9687604

Abstract Article

Select item 96038606.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 86268567.

Conditional Deletion of Cytoplasmic Dynein Heavy Chain in Postnatal Photoreceptors

Tiffanie M. Dahl, Michelle Reed, Cecilia D. Gerstner, Wolfgang Baehr

Invest Ophthalmol Vis Sci. 2021 Nov; 62(14): 23. Published online 2021 Nov 22. doi: 10.1167/iovs.62.14.23

PMCID:: PMC8626856

Abstract Article PDF–23M

Select item 79519038.

Effect of conditional deletion of cytoplasmic dynein heavy chain DYNC1H1 on postnatal photoreceptors

Tiffanie M. Dahl, Michelle Reed, Cecilia D. Gerstner, Guoxin Ying, Wolfgang Baehr

PLoS One. 2021; 16(3): e0248354. Published online 2021 Mar 11. doi: 10.1371/journal.pone.0248354

PMCID:: PMC7951903

Abstract Article PDF–6.2M

Select item 79387709.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 676303910.

NudC Associates with Lis1 and the Dynein Motor at the Leading Pole of Neurons

Jonathan P. Aumais, James R. Tunstead, Robert S. McNeil, Bruce T. Schaar, Susan K. McConnell, Sue-Hwa Lin, Gary D. Clark, Li-yuan Yu-Lee

J Neurosci. 2001 Dec 15; 21(24): RC187. doi: 10.1523/JNEUROSCI.21-24-j0002.2001

PMCID:: PMC6763039

Abstract PDF–1.1M

Select item 670020711.

Mice with an autosomal dominant Charcot-Marie-Tooth type 2O disease mutation in both dynein alleles display severe moto-sensory phenotypes

Swaran Nandini, Jami L. Conley Calderon, Thywill T. Sabblah, Rachal Love, Linda E. King, Stephen J. King

Sci Rep. 2019; 9: 11979. Published online 2019 Aug 19. doi: 10.1038/s41598-019-48431-7

PMCID:: PMC6700207

Abstract Article PDF–3.0M

Select item 667343112.

Proprioceptive Sensory Neuropathy in Mice with a Mutation in the Cytoplasmic Dynein Heavy Chain 1 Gene

Xiang-Jun Chen, Eleni N. Levedakou, Kathleen J. Millen, Robert L. Wollmann, Betty Soliven, Brian Popko

J Neurosci. 2007 Dec 26; 27(52): 14515–14524. doi: 10.1523/JNEUROSCI.4338-07.2007

PMCID:: PMC6673431

Abstract Article PDF–473K

Select item 649289513.

Dync1h1 Mutation Causes Proprioceptive Sensory Neuron Loss and Impaired Retrograde Axonal Transport of Dorsal Root Ganglion Neurons

Jing Zhao, Yi Wang, Huan Xu, Yuan Fu, Ting Qian, Deng Bo, Yan‐Xin Lu, Yi Xiong, Jun Wan, Xiang Zhang, Qiang Dong, Xiang‐Jun Chen

CNS Neurosci Ther. 2016 Jul; 22(7): 593–601. Published online 2016 Apr 15. doi: 10.1111/cns.12552

PMCID:: PMC6492895

Abstract Article PDF–651K

Select item 631390014.

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization

Darryl S. Watkins, Jason D. True, Amber L. Mosley, Anthony J. Baucum, II

Proteomes. 2018 Dec; 6(4): 53. Published online 2018 Dec 17. doi: 10.3390/proteomes6040053

Correction in:: Proteomes. 2019 Mar; 7(1): 7.

PMCID:: PMC6313900

Abstract Article PDF–2.5M

Select item 626277715.

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow

Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher

J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214

PMCID:: PMC6262777

Abstract Article

Select item 624418316.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 586818117.

CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice

Jin Li, Su-Ping Deng, Gang Wei, Peng Yu

Database (Oxford) 2018; 2018: bay012. Published online 2018 Mar 23. doi: 10.1093/database/bay012

PMCID:: PMC5868181

Abstract Article PDF–653K

Select item 586277118.

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies

David K. Breslow, Sascha Hoogendoorn, Adam R. Kopp, David W. Morgens, Brandon K. Vu, Margaret C. Kennedy, Kyuho Han, Amy Li, Gaelen T. Hess, Michael C. Bassik, James K. Chen, Maxence V. Nachury

Nat Genet. Author manuscript; available in PMC 2018 Aug 19.

Published in final edited form as: Nat Genet. 2018 Mar; 50(3): 460–471. Published online 2018 Feb 19. doi: 10.1038/s41588-018-0054-7

PMCID:: PMC5862771

Abstract Article PDF–2.5M

Select item 578900219.

A novel mouse model carrying a human cytoplasmic dynein mutation shows motor behavior deficits consistent with Charcot-Marie-Tooth type 2O disease

Thywill T. Sabblah, Swaran Nandini, Aaron P. Ledray, Julio Pasos, Jami L. Conley Calderon, Rachal Love, Linda E. King, Stephen J. King

Sci Rep. 2018; 8: 1739. Published online 2018 Jan 29. doi: 10.1038/s41598-018-20081-1

PMCID:: PMC5789002

Abstract Article PDF–3.3M

Select item 572553320.

Eml1 loss impairs apical progenitor spindle length and soma shape in the developing cerebral cortex

Sara Bizzotto, Ana Uzquiano, Florent Dingli, Dmitry Ershov, Anne Houllier, Guillaume Arras, Mark Richards, Damarys Loew, Nicolas Minc, Alexandre Croquelois, Anne Houdusse, Fiona Francis

Sci Rep. 2017; 7: 17308. Published online 2017 Dec 11. doi: 10.1038/s41598-017-15253-4

PMCID:: PMC5725533

Abstract Article PDF–2.3M

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