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Select item 111930601.

Mitochondrial aldehyde dehydrogenase rescues against diabetic cardiomyopathy through GSK3β-mediated preservation of mitochondrial integrity and Parkin-mediated mitophagy

Yingmei Zhang, Rongjun Zou, Miyesaier Abudureyimu, Qiong Liu, Jipeng Ma, Haixia Xu, Wei Yu, Jian Yang, Jianguo Jia, Sanli Qian, Haichang Wang, Yang Yang, Xin Wang, Xiaoping Fan, Jun Ren

J Mol Cell Biol. 2023 Sep; 15(9): mjad056. Published online 2023 Sep 28. doi: 10.1093/jmcb/mjad056

Correction in:: J Mol Cell Biol. 2024 Sep 4

PMCID:: PMC11193060

Abstract Article PDF–5.7M

Select item 111138422.

Apaf1-deficient cortical neurons exhibit defects in axonal outgrowth

Daniela De Zio, Francesca Molinari, Salvatore Rizza, Lucia Gatta, Maria Teresa Ciotti, Anna Maria Salvatore, Søs Grønbæk Mathiassen, Andrzej W. Cwetsch, Giuseppe Filomeni, Giuseppe Rosano, Elisabetta Ferraro

Cell Mol Life Sci. 2015 Nov; 72(21): 4173–4191. Published online 2015 May 15. doi: 10.1007/s00018-015-1927-x

PMCID:: PMC11113842

Abstract Article PDF–1.8M

Select item 111134943.

GSK3 and β-catenin determines functional expression of sodium channels at the axon initial segment

Mónica Tapia, Ana Del Puerto, Alberto Puime, Diana Sánchez-Ponce, Laure Fronzaroli-Molinieres, Noemí Pallas-Bazarra, Edmond Carlier, Pierre Giraud, Dominique Debanne, Francisco Wandosell, Juan José Garrido

Cell Mol Life Sci. 2013 Jan; 70(1): 105–120. Published online 2012 Jul 5. doi: 10.1007/s00018-012-1059-5

PMCID:: PMC11113494

Abstract Article PDF–3.6M

Select item 111054744.

PTEN–GSK3β–MOB1 axis controls neurite outgrowth in vitro and in vivo

Zhiwen Song, Xiu Han, Hongjun Zou, Bin Zhang, Ya Ding, Xu Xu, Jian Zeng, Jinbo Liu, Aihua Gong

Cell Mol Life Sci. 2018 Dec; 75(23): 4445–4464. Published online 2018 Aug 1. doi: 10.1007/s00018-018-2890-0

PMCID:: PMC11105474

Abstract Article PDF–4.0M

Select item 111025605.

miR-709 exerts an angiogenic effect through a FGF2 upregulation induced by a GSK3B downregulation

Koji Ueno, Hiroshi Kurazumi, Ryo Suzuki, Masashi Yanagihara, Takahiro Mizoguchi, Takasuke Harada, Noriyasu Morikage, Kimikazu Hamano

Sci Rep. 2024; 14: 11372. Published online 2024 May 18. doi: 10.1038/s41598-024-62340-4

PMCID:: PMC11102560

Abstract Article PDF–2.0M

Select item 110796056.

Mitochondrial translation failure represses cholesterol gene expression via Pyk2-Gsk3β-Srebp2 axis

Takahiro Toshima, Mikako Yagi, Yura Do, Haruka Hirai, Yuya Kunisaki, Dongchon Kang, Takeshi Uchiumi

Life Sci Alliance. 2024 Jul; 7(7): e202302423. Published online 2024 May 8. doi: 10.26508/lsa.202302423

PMCID:: PMC11079605

Abstract Article PDF–2.6M

Select item 109814467.

NLRP3 Inflammasome Priming in the Retina of Diabetic Mice Requires REDD1-Dependent Activation of GSK3β

Christopher M. McCurry, Siddharth Sunilkumar, Sandeep M. Subrahmanian, Esma I. Yerlikaya, Allyson L. Toro, Ashley M. VanCleave, Shaunaci A. Stevens, Alistair J. Barber, Jeffery M. Sundstrom, Michael D. Dennis

Invest Ophthalmol Vis Sci. 2024 Mar; 65(3): 34. Published online 2024 Mar 28. doi: 10.1167/iovs.65.3.34

PMCID:: PMC10981446

Abstract Article PDF–2.5M

Select item 109729208.

IL-6 Enhances the Activation of PI3K-AKT/mTOR-GSK-3β by Upregulating GRPR in Hippocampal Neurons of Autistic Mice

Heli Li, Xinyuan Wang, Cong Hu, Jinru Cui, Hao Li, Xiaoping Luo, Yan Hao

J Neuroimmune Pharmacol. 2024; 19(1): 12. Published online 2024 Mar 27. doi: 10.1007/s11481-024-10111-3

PMCID:: PMC10972920

Abstract Article PDF–5.4M

Select item 109507079.

Inhibition of glycogen synthase kinase-3 enhances NRF2 protein stability, nuclear localisation and target gene transcription in pancreatic beta cells

Chinmai Patibandla, Lidy van Aalten, Albena T. Dinkova-Kostova, Tadashi Honda, Antonio Cuadrado, Raquel Fernández-Ginés, Alison D. McNeilly, John D. Hayes, James Cantley, Calum Sutherland

Redox Biol. 2024 May; 71: 103117. Published online 2024 Mar 7. doi: 10.1016/j.redox.2024.103117

PMCID:: PMC10950707

Abstract Article PDF–7.6M

Select item 1086436310.

Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy

Yan Guo, Pan Xiang, Xiaojiao Sun, Wei Liu, Jiafeng Zhou, Bin Yin, Lin Hou, Boqin Qiang, Huiliang Li, Pengcheng Shu, Xiaozhong Peng

Signal Transduct Target Ther. 2024; 9: 32. Published online 2024 Feb 14. doi: 10.1038/s41392-024-01742-2

PMCID:: PMC10864363

Abstract Article PDF–9.9M

Select item 1076537911.

Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration

Lixiang Sun, Xiaowei Zhang, Shuai Wu, Youxi Liu, Christian F. Guerrero-Juarez, Wenjie Liu, Jinwen Huang, Qian Yao, Meimei Yin, Jiacheng Li, Raul Ramos, Yanhang Liao, Rundong Wu, Tian Xia, Xinyuan Zhang, Yichun Yang, Fengwu Li, Shujun Heng, Wenlu Zhang, Minggang Yang, Chi-Meng Tzeng, Chao Ji, Maksim V. Plikus, Richard L. Gallo, Ling-juan Zhang

Cell Rep. Author manuscript; available in PMC 2024 Jan 4.

Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112647. Published online 2023 Jun 16. doi: 10.1016/j.celrep.2023.112647

PMCID:: PMC10765379

Abstract Article PDF–6.0M

Select item 1069825812.

Loss of GSK3β in hematopoietic stem cells results in normal hematopoiesis in mice

Grace Lee, Jude Franklin, Kalpana Gupta, Ruifu Liu, Lan Zhou, Christopher Ryder, Lukasz Sobieraj, Luke Molitor, Olubukola Abiona, Howard Meyerson, Indrani Das, Zachary Jackson, David N. Wald

Blood Adv. 2023 Dec 12; 7(23): 7185–7189. Published online 2023 Oct 24. doi: 10.1182/bloodadvances.2022008094

PMCID:: PMC10698258

Article PDF–1.7M

Select item 1067987913.

FUNDC2, a mitochondrial outer membrane protein, mediates triple-negative breast cancer progression via the AKT/GSK3β/GLI1 pathway: FUNDC2 mediates TNBC progression via the AKT/GSK3β/GLI1 pathway

Liyang Yin, Renxian Cao, Zhuoqing Liu, Gang Luo, Yu Li, Xiaolong Zhou, Xiguang Chen, Ying Wu, Jun He, Xuyu Zu, Yingying Shen

Acta Biochim Biophys Sin (Shanghai) 2023 Nov 25; 55(11): 1770–1783. Published online 2023 Sep 11. doi: 10.3724/abbs.2023142

PMCID:: PMC10679879

Abstract Article PDF–4.0M

Select item 1053189014.

Diabetic Endothelial Cell Glycogen Synthase Kinase 3β Activation Induces VCAM1 Ectodomain Shedding

Masuma Akter Brishti, Somasundaram Raghavan, Kennedy Lamar, Udai P. Singh, Daniel M. Collier, M. Dennis Leo

Int J Mol Sci. 2023 Sep; 24(18): 14105. Published online 2023 Sep 14. doi: 10.3390/ijms241814105

PMCID:: PMC10531890

Abstract Article PDF–1.9M

Select item 1051694915.

A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia

Anna Laddach, Song Hui Chng, Reena Lasrado, Fränze Progatzky, Michael Shapiro, Alek Erickson, Marisol Sampedro Castaneda, Artem V. Artemov, Ana Carina Bon-Frauches, Eleni-Maria Amaniti, Jens Kleinjung, Stefan Boeing, Sila Ultanir, Igor Adameyko, Vassilis Pachnis

Nat Commun. 2023; 14: 5904. Published online 2023 Sep 22. doi: 10.1038/s41467-023-41492-3

PMCID:: PMC10516949

Abstract Article PDF–4.8M

Select item 1040743216.

REDD1-dependent GSK3β dephosphorylation promotes NF-κB activation and macrophage infiltration in the retina of diabetic mice

Siddharth Sunilkumar, Ashley M. VanCleave, Christopher M. McCurry, Allyson L. Toro, Shaunaci A. Stevens, Scot R. Kimball, Michael D. Dennis

J Biol Chem. 2023 Aug; 299(8): 104991. Published online 2023 Jun 29. doi: 10.1016/j.jbc.2023.104991

PMCID:: PMC10407432

Abstract Article PDF–1.7M

Select item 1038032017.

GSK3β Inhibition Ameliorates Atherosclerotic Calcification

Xinjiang Cai, Yan Zhao, Yang Yang, Xiuju Wu, Li Zhang, Jocelyn A. Ma, Jaden Ji, Kristina I. Boström, Yucheng Yao

Int J Mol Sci. 2023 Jul; 24(14): 11638. Published online 2023 Jul 19. doi: 10.3390/ijms241411638

PMCID:: PMC10380320

Abstract Article PDF–2.2M

Select item 1031804318.

Peli3 ablation ameliorates acetaminophen-induced liver injury through inhibition of GSK3β phosphorylation and mitochondrial translocation

Jaewon Lee, Jihoon Ha, Jun-Hyeong Kim, Dongyeob Seo, Minbeom Kim, Yerin Lee, Seong Shil Park, Dahee Choi, Jin Seok Park, Young Jae Lee, Siyoung Yang, Kyung-Min Yang, Su Myung Jung, Suntaek Hong, Seung-Hoi Koo, Yong-Soo Bae, Seong-Jin Kim, Seok Hee Park

Exp Mol Med. 2023 Jun; 55(6): 1218–1231. Published online 2023 Jun 1. doi: 10.1038/s12276-023-01009-w

PMCID:: PMC10318043

Abstract Article PDF–3.0M

Select item 1030895819.

DTX3L Enhances Type I Interferon Antiviral Response by Promoting the Ubiquitination and Phosphorylation of TBK1

Jiaqi Huang, Zhengrong Chen, Yunfei Ye, Yu Shao, Peijie Zhu, Xiaoping Li, Yu Ma, Fei Xu, Ji Zhou, Mengyun Wu, Xiu Gao, Yi Yang, Jinping Zhang, Chuangli Hao

J Virol. 2023 Jun; 97(6): e00687-23. Published online 2023 May 31. doi: 10.1128/jvi.00687-23

PMCID:: PMC10308958

Abstract Article PDF–4.8M

Select item 1024951020.

Tau and GSK-3β are critical contributors to α-synuclein-mediated post-stroke brain damage

Suresh L Mehta, TaeHee Kim, Bharath Chelluboina, Raghu Vemuganti

Neuromolecular Med. Author manuscript; available in PMC 2023 Jun 8.

Published in final edited form as: Neuromolecular Med. 2023 Mar; 25(1): 94–101. Published online 2022 Nov 30. doi: 10.1007/s12017-022-08731-0

PMCID:: PMC10249510

Abstract Article PDF–691K

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