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Select item 108532161.

Compromised transcription-mRNA export factor THOC2 causes R-loop accumulation, DNA damage and adverse neurodevelopment

Rudrarup Bhattacharjee, Lachlan A. Jolly, Mark A. Corbett, Ing Chee Wee, Sushma R. Rao, Alison E. Gardner, Tarin Ritchie, Eline J. H. van Hugte, Ummi Ciptasari, Sandra Piltz, Jacqueline E. Noll, Nazzmer Nazri, Clare L. van Eyk, Melissa White, Dani Fornarino, Cathryn Poulton, Gareth Baynam, Lyndsey E. Collins-Praino, Marten F. Snel, Nael Nadif Kasri, Kim M. Hemsley, Paul Q. Thomas, Raman Kumar, Jozef Gecz

Nat Commun. 2024; 15: 1210. Published online 2024 Feb 8. doi: 10.1038/s41467-024-45121-5

PMCID:: PMC10853216

Abstract Article PDF–11M

Select item 104629782.

Incomplete activation of Alyref and Gabpb1 leads to preimplantation arrest in cloned mouse embryos

Shunya Ihashi, Mizuto Hamanaka, Masaya Kaji, Ryunosuke Mori, Shuntaro Nishizaki, Miki Mori, Yuma Imasato, Kimiko Inoue, Shogo Matoba, Narumi Ogonuki, Atsushi Takasu, Misaki Nakamura, Kazuya Matsumoto, Masayuki Anzai, Atsuo Ogura, Masahito Ikawa, Kei Miyamoto

Life Sci Alliance. 2023 Nov; 6(11): e202302296. Published online 2023 Aug 28. doi: 10.26508/lsa.202302296

PMCID:: PMC10462978

Abstract Article PDF–3.8M

Select item 83132393.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 79387704.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 72360605.

Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism

Arielle N. Valdez-Sinon, Austin Lai, Liang Shi, Carly L. Lancaster, Avanti Gokhale, Victor Faundez, Gary J. Bassell

iScience. 2020 May 22; 23(5): 101132. Published online 2020 May 1. doi: 10.1016/j.isci.2020.101132

PMCID:: PMC7236060

Abstract Article PDF–6.1M

Select item 69939256.

Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers

Chao Wang, Bin Zhang, Anna C. Ratliff, Justine Arrington, Jingjuan Chen, Yan Xiong, Feng Yue, Yaohui Nie, Keping Hu, Wen Jin, W. Andy Tao, Christine A. Hrycyna, Xiaobo Sun, Shihuan Kuang

FASEB J. 2019 Aug; 33(8): 9672–9684. Published online 2019 Jun 4. doi: 10.1096/fj.201900582R

PMCID:: PMC6993925

Abstract Article

Select item 68683747.

ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation

Yan Rong, Shu-Yan Ji, Ye-Zhang Zhu, Yun-Wen Wu, Li Shen, Heng-Yu Fan

Nucleic Acids Res. 2019 Dec 2; 47(21): 11387–11402. Published online 2019 Oct 10. doi: 10.1093/nar/gkz863

PMCID:: PMC6868374

Abstract Article PDF–6.8M

Select item 66023008.

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules

Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer

J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252

PMCID:: PMC6602300

Abstract Article

Select item 64059029.

Iws1 and Spt6 Regulate Trimethylation of Histone H3 on Lysine 36 through Akt Signaling and are Essential for Mouse Embryonic Genome Activation

Reza K. Oqani, Tao Lin, Jae Eun Lee, Jeong Won Kang, Hyun Young Shin, Dong Il Jin

Sci Rep. 2019; 9: 3831. Published online 2019 Mar 7. doi: 10.1038/s41598-019-40358-3

PMCID:: PMC6405902

Abstract Article PDF–2.5M

Select item 633346010.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Abstract Article PDF–2.7M

Select item 593680011.

Elucidation of the 14-3-3ζ interactome reveals critical roles of RNA-splicing factors during adipogenesis

Yves Mugabo, Mina Sadeghi, Nancy N. Fang, Thibault Mayor, Gareth E. Lim

J Biol Chem. 2018 May 4; 293(18): 6736–6750. Published online 2018 Mar 12. doi: 10.1074/jbc.M117.816272

PMCID:: PMC5936800

Abstract Article PDF–2.4M

Select item 586277112.

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies

David K. Breslow, Sascha Hoogendoorn, Adam R. Kopp, David W. Morgens, Brandon K. Vu, Margaret C. Kennedy, Kyuho Han, Amy Li, Gaelen T. Hess, Michael C. Bassik, James K. Chen, Maxence V. Nachury

Nat Genet. Author manuscript; available in PMC 2018 Aug 19.

Published in final edited form as: Nat Genet. 2018 Mar; 50(3): 460–471. Published online 2018 Feb 19. doi: 10.1038/s41588-018-0054-7

PMCID:: PMC5862771

Abstract Article PDF–2.5M

Select item 564508213.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594

PMCID:: PMC5645082

Abstract Article PDF–2.3M

Select item 500746614.

VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease

Xing Guo, XiaoYan Sun, Di Hu, Ya-Juan Wang, Hisashi Fujioka, Rajan Vyas, Sudha Chakrapani, Amit Umesh Joshi, Yu Luo, Daria Mochly-Rosen, Xin Qi

Nat Commun. 2016; 7: 12646. Published online 2016 Aug 26. doi: 10.1038/ncomms12646

PMCID:: PMC5007466

Abstract Article PDF–5.4M

Select item 457685815.

Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin

Xiaolai Zhou, Lirong Sun, Francisco Bastos de Oliveira, Xiaoyang Qi, William J. Brown, Marcus B. Smolka, Ying Sun, Fenghua Hu

J Cell Biol. 2015 Sep 14; 210(6): 991–1002. doi: 10.1083/jcb.201502029

PMCID:: PMC4576858

Abstract Article PDF–3.0M

Select item 407349416.

The Central Role of EED in the Orchestration of Polycomb Group Complexes

Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan

Nat Commun. Author manuscript; available in PMC 2014 Jul 24.

Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127

PMCID:: PMC4073494

Abstract Article PDF–2.1M

Select item 392378317.

Competitive and Cooperative Interactions Mediate RNA Transfer from Herpesvirus Saimiri ORF57 to the Mammalian Export Adaptor ALYREF

Richard B. Tunnicliffe, Guillaume M. Hautbergue, Stuart A. Wilson, Priti Kalra, Alexander P. Golovanov

PLoS Pathog. 2014 Feb; 10(2): e1003907. Published online 2014 Feb 13. doi: 10.1371/journal.ppat.1003907

PMCID:: PMC3923783

Abstract Article PDF–1.7M

Select item 379774818.

The AERO System: A 3D-Like Approach for Recording Gene Expression Patterns in the Whole Mouse Embryo

Hirohito Shimizu, Atsushi Kubo, Kenta Uchibe, Megumi Hashimoto, Shigetoshi Yokoyama, Shuji Takada, Kazuhiko Mitsuoka, Hiroshi Asahara

PLoS One. 2013; 8(10): e75754. Published online 2013 Oct 16. doi: 10.1371/journal.pone.0075754

PMCID:: PMC3797748

Abstract Article PDF–564K

Select item 355398419.

Reverse engineering a mouse embryonic stem cell-specific transcriptional network reveals a new modulator of neuronal differentiation

Rossella De Cegli, Simona Iacobacci, Gemma Flore, Gennaro Gambardella, Lei Mao, Luisa Cutillo, Mario Lauria, Joachim Klose, Elizabeth Illingworth, Sandro Banfi, Diego di Bernardo

Nucleic Acids Res. 2013 Jan; 41(2): 711–726. Published online 2012 Nov 22. doi: 10.1093/nar/gks1136

PMCID:: PMC3553984

Abstract Article PDF–15M

Select item 344801220.

Transcription factor Foxp3 and its protein partners form a complex regulatory network

Dipayan Rudra, Paul deRoos, Ashutosh Chaudhry, Rachel Niec, Aaron Arvey, Robert M. Samstein, Christina Leslie, Scott A. Shaffer, David R. Goodlett, Alexander Y. Rudensky

Nat Immunol. Author manuscript; available in PMC 2013 Apr 1.

Published in final edited form as: Nat Immunol. 2012 Oct; 13(10): 1010–1019. Published online 2012 Aug 26. doi: 10.1038/ni.2402

PMCID:: PMC3448012

Abstract Article PDF–2.6M

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