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Select item 110684081.

Wnt signaling regulates ion channel expression to promote smooth muscle and cartilage formation in developing mouse trachea

Nicholas X. Russell, Kaulini Burra, Ronak M. Shah, Natalia Bottasso-Arias, Megha Mohanakrishnan, John Snowball, Harshavardhana H. Ediga, Satish K. Madala, Debora Sinner

Am J Physiol Lung Cell Mol Physiol. 2023 Dec 1; 325(6): L788–L802. Published online 2023 Oct 24. doi: 10.1152/ajplung.00024.2023

PMCID:: PMC11068408

Abstract Article

Select item 109858382.

MAP3K1 regulates female reproductive tract development

Eiki Kimura, Maureen Mongan, Bo Xiao, Antonius Christianto, Jingjing Wang, Vinicius S. Carreira, Brad Bolon, Xiang Zhang, Katherine A. Burns, Jacek Biesiada, Mario Medvedovic, Alvaro Puga, Ying Xia

Dis Model Mech. 2024 Mar 1; 17(3): dmm050669. Published online 2024 Mar 28. doi: 10.1242/dmm.050669

PMCID:: PMC10985838

Abstract Article

Select item 108840303.

TREX tetramer disruption alters RNA processing necessary for corticogenesis in THOC6 Intellectual Disability Syndrome

Elizabeth A. Werren, Geneva R. LaForce, Anshika Srivastava, Delia R. Perillo, Shaokun Li, Katherine Johnson, Safa Baris, Brandon Berger, Samantha L. Regan, Christian D. Pfennig, Sonja de Munnik, Rolph Pfundt, Malavika Hebbar, Raúl Jimenez-Heredia, Elif Karakoc-Aydiner, Ahmet Ozen, Jasmin Dmytrus, Ana Krolo, Ken Corning, E. J. Prijoles, Raymond J. Louie, Robert Roger Lebel, Thuy-Linh Le, Jeanne Amiel, Christopher T. Gordon, Kaan Boztug, Katta M. Girisha, Anju Shukla, Stephanie L. Bielas, Ashleigh E. Schaffer

Nat Commun. 2024; 15: 1640. Published online 2024 Feb 22. doi: 10.1038/s41467-024-45948-y

PMCID:: PMC10884030

Abstract Article PDF–7.0M

Select item 107535884.

Aberrant centrosome biogenesis disrupts nephron and collecting duct progenitor growth and fate resulting in fibrocystic kidney disease

Tao Cheng, Chidera Agwu, Kyuhwan Shim, Baolin Wang, Sanjay Jain, Moe R. Mahjoub

Development. 2023 Dec 15; 150(24): dev201976. Published online 2023 Dec 21. doi: 10.1242/dev.201976

PMCID:: PMC10753588

Abstract Article

Select item 105457975.

Pregnane X receptor activation alleviates renal fibrosis in mice via interacting with p53 and inhibiting the Wnt7a/β-catenin signaling

Wen-hua Ming, Zhi-lin Luan, Yao Yao, Hang-chi Liu, Shu-yuan Hu, Chun-xiu Du, Cong Zhang, Yi-hang Zhao, Ying-zhi Huang, Xiao-wan Sun, Rong-fang Qiao, Hu Xu, You-fei Guan, Xiao-yan Zhang

Acta Pharmacol Sin. 2023 Oct; 44(10): 2075–2090. Published online 2023 Jun 21. doi: 10.1038/s41401-023-01113-7

PMCID:: PMC10545797

Abstract Article PDF–9.1M

Select item 101478296.

WNT7A suppresses adipogenesis of skeletal muscle mesenchymal stem cells and fatty infiltration through the alternative Wnt-Rho-YAP/TAZ signaling axis

Chengcheng Fu, Britney Chin-Young, GaYoung Park, Mariana Guzmán-Seda, Damien Laudier, Woojin M. Han

Stem Cell Reports. 2023 Apr 11; 18(4): 999–1014. Published online 2023 Mar 30. doi: 10.1016/j.stemcr.2023.03.001

PMCID:: PMC10147829

Abstract Article PDF–6.3M

Select item 99909907.

Functional genomics analysis identifies loss of HNF1B function as a cause of Mayer–Rokitansky–Küster–Hauser syndrome

Ella Thomson, Minh Tran, Gorjana Robevska, Katie Ayers, Jocelyn van der Bergen, Prarthna Gopalakrishnan Bhaskaran, Eric Haan, Silvia Cereghini, Alla Vash-Margita, Miranda Margetts, Alison Hensley, Quan Nguyen, Andrew Sinclair, Peter Koopman, Emanuele Pelosi

Hum Mol Genet. 2023 Mar 15; 32(6): 1032–1047. Published online 2022 Oct 25. doi: 10.1093/hmg/ddac262

PMCID:: PMC9990990

Abstract Article PDF–2.2M

Select item 99894758.

Basal Cell–derived WNT7A Promotes Fibrogenesis at the Fibrotic Niche in Idiopathic Pulmonary Fibrosis

Guanling Huang, Jiurong Liang, Kevin Huang, Xue Liu, Forough Taghavifar, Changfu Yao, Tanyalak Parimon, Ningshan Liu, Kristy Dai, Adam Aziz, Yizhou Wang, Richard T. Waldron, Hongmei Mou, Barry Stripp, Paul W. Noble, Dianhua Jiang

Am J Respir Cell Mol Biol. 2023 Mar 1; 68(3): 302–313. Published online 2022 Nov 1. doi: 10.1165/rcmb.2022-0074OC

PMCID:: PMC9989475

Abstract Article PDF–1.5M

Select item 98457459.

Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development

Laura Simonson, Ethan Oldham, Hao Chang

Development. 2022 Nov 15; 149(22): dev200816. Published online 2022 Nov 16. doi: 10.1242/dev.200816

PMCID:: PMC9845745

Abstract Article

Select item 972769910.

En1 and Lmx1b do not recapitulate embryonic dorsal-ventral limb patterning functions during mouse digit tip regeneration

Gemma L. Johnson, Morgan B. Glasser, Julia F. Charles, Jeffrey Duryea, Jessica A. Lehoczky

Cell Rep. Author manuscript; available in PMC 2022 Dec 7.

Published in final edited form as: Cell Rep. 2022 Nov 22; 41(8): 111701. doi: 10.1016/j.celrep.2022.111701

PMCID:: PMC9727699

Abstract Article PDF–1.7M

Select item 948196911.

Integrated analysis of Wnt signalling system component gene expression

Paula Murphy, Chris Armit, Bill Hill, Shanmugasundaram Venkataraman, Patrick Frankel, Richard A. Baldock, Duncan R. Davidson

Development. 2022 Aug 15; 149(16): dev200312. Published online 2022 Aug 15. doi: 10.1242/dev.200312

PMCID:: PMC9481969

Abstract Article

Select item 946963312.

Exosomal Wnt7a from a low metastatic subclone promotes lung metastasis of a highly metastatic subclone in the murine 4t1 breast cancer

Chunning Li, Teizo Yoshimura, Miao Tian, Yuze Wang, Takamasa Kondo, Ken-Ichi Yamamoto, Masayoshi Fujisawa, Toshiaki Ohara, Masakiyo Sakaguchi, Akihiro Matsukawa

Breast Cancer Res. 2022; 24: 60. Published online 2022 Sep 12. doi: 10.1186/s13058-022-01557-5

PMCID:: PMC9469633

Abstract Article PDF–7.7M

Select item 933525813.

Development and characterization of human fetal female reproductive tract organoids to understand Müllerian duct anomalies

Varshini D. Venkata, M. Fairuz B. Jamaluddin, Jyoti Goad, Hannah R. Drury, Melissa A. Tadros, Rebecca Lim, Ajay Karakoti, Rachel O’Sullivan, Yvette Ius, Kenneth Jaaback, Pravin Nahar, Pradeep S. Tanwar

Proc Natl Acad Sci U S A. 2022 Jul 26; 119(30): e2118054119. Published online 2022 Jul 18. doi: 10.1073/pnas.2118054119

PMCID:: PMC9335258

Abstract Article PDF–3.8M

Select item 927593314.

Long-noncoding RNA HOXA transcript at the distal tip ameliorates the insulin resistance and hepatic gluconeogenesis in mice with gestational diabetes mellitus via the microRNA-423-5p/wingless-type MMTV integration site family member 7A axis

Qianqian Cao, Xiaojie Zhang, Fengfeng Xie, Yangping Li, Feng Lin

Bioengineered. 2022; 13(5): 13224–13237. Published online 2022 Jun 1. doi: 10.1080/21655979.2022.2076982

PMCID:: PMC9275933

Abstract Article PDF–9.0M

Select item 914856415.

The WNT7A/WNT7B/GPR124/RECK signaling module plays an essential role in mammalian limb development

Yanshu Wang, Arjun Venkatesh, Jiajia Xu, Mingxin Xu, John Williams, Philip M. Smallwood, Aaron James, Jeremy Nathans

Development. 2022 May 1; 149(9): dev200340. Published online 2022 May 12. doi: 10.1242/dev.200340

PMCID:: PMC9148564

Abstract Article

Select item 866506116.

Spatial and temporal expression of PORCN is highly dynamic in the developing mouse cochlea.

Brianna L. Oliver, Caryl A. Young, Vidhya Munnamalai

Gene Expr Patterns. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Gene Expr Patterns. 2021 Sep 20; 42: 119214. Published online 2021 Sep 20. doi: 10.1016/j.gep.2021.119214

PMCID:: PMC8665061

Abstract Article PDF–4.6M

Select item 831323917.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 793877018.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 776992019.

Wnt-Dependent Oligodendroglial-Endothelial Interactions Regulate White Matter Vascularization and Attenuate Injury

Manideep Chavali, Maria José Ulloa-Navas, Pedro Pérez-Borredá, Jose Manuel Garcia-Verdugo, Patrick S. McQuillen, Eric J. Huang, David H. Rowitch

Neuron. Author manuscript; available in PMC 2020 Dec 29.

Published in final edited form as: Neuron. 2020 Dec 23; 108(6): 1130–1145.e5. Published online 2020 Oct 20. doi: 10.1016/j.neuron.2020.09.033

PMCID:: PMC7769920

Abstract Article PDF–3.9M

Select item 766312320.

Targeted Disruption of Mouse Dip2B Leads to Abnormal Lung Development and Prenatal Lethality

Rajiv Kumar Sah, Jun Ma, Fatoumata Binta Bah, Zhenkai Xing, Salah Adlat, Zin Ma Oo, Yajun Wang, Noor Bahadar, Ameer Ali Bohio, Farooq Hayel Nagi, Xuechao Feng, Luqing Zhang, Yaowu Zheng

Int J Mol Sci. 2020 Nov; 21(21): 8223. Published online 2020 Nov 3. doi: 10.3390/ijms21218223

PMCID:: PMC7663123

Abstract Article PDF–4.7M

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