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Items: 1 to 20 of 35

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
ERK and c-Myc signaling in host-derived tumor endothelial cells is essential for solid tumor growth
Zehua Zuo, Jie Liu, Zhihao Sun, Yu-Wei Cheng, Michael Ewing, Thomas H. Bugge, Toren Finkel, Stephen H. Leppla, Shihui Liu
Proc Natl Acad Sci U S A. 2023 Jan 3; 120(1): e2211927120. Published online 2022 Dec 27. doi: 10.1073/pnas.2211927120
PMCID:
PMC9910475
AbstractArticlePDF–1.2M
3.
Anthrax toxins regulate pain signaling and can deliver molecular cargoes into Antxr2+ DRG sensory neurons
Nicole J. Yang, Jörg Isensee, Dylan Neel, Andreza U. Quadros, Han-Xiong Bear Zhang, Justas Lauzadis, Sai Man Liu, Stephanie Shiers, Andreea Belu, Shilpa Palan, Sandra Marlin, Jacquie Maignel, Angela Kennedy-Curran, Victoria S. Tong, Mahtab Moayeri, Pascal Röderer, Anja Nitzsche, Mike Lu, Bradley L. Pentelute, Oliver Brüstle, Vineeta Tripathi, Keith A. Foster, Theodore J. Price, R. John Collier, Stephen H. Leppla, Michelino Puopolo, Bruce P. Bean, Thiago M. Cunha, Tim Hucho, Isaac M. Chiu
Nat Neurosci. Author manuscript; available in PMC 2022 Aug 19.
Published in final edited form as: Nat Neurosci. 2022 Feb; 25(2): 168–179. Published online 2021 Dec 20. doi: 10.1038/s41593-021-00973-8
PMCID:
PMC9388775
AbstractArticlePDF–4.7M
4.
Capillary Morphogenesis gene 2 (CMG2) mediates growth factor-induced angiogenesis by regulating endothelial cell chemotaxis
Lorna M. Cryan, Tsz-Ming Tsang, Jessica Stiles, Lauren Bazinet, Sai Lun Lee, Samuel Garrard, Erika Madrian, Cody Roberts, Jessie Payne, Andrew Jensen, Arthur E. Frankel, P. Christine Ackroyd, Kenneth A. Christensen, Michael S. Rogers
Angiogenesis. Author manuscript; available in PMC 2023 Aug 1.
Published in final edited form as: Angiogenesis. 2022 Aug; 25(3): 397–410. Published online 2022 Feb 25. doi: 10.1007/s10456-022-09833-w
PMCID:
PMC9250616
AbstractArticlePDF–1.7M
5.
Imaging of anthrax intoxication in mice reveals shared and individual functions of surface receptors CMG-2 and TEM-8 in cellular toxin entry
Carly Merritt, Elizabeth M. Chun, Rasem J. Fattah, Lakmali M. Silva, Quinn Q. Ma, Mahtab Moayeri, Dennis Paliga, Sebastian Neumann, Rolf Heumann, Stephen H. Leppla, Thomas H. Bugge
J Biol Chem. 2022 Jan; 298(1): 101467. Published online 2021 Dec 4. doi: 10.1016/j.jbc.2021.101467
PMCID:
PMC8716333
AbstractArticlePDF–6.5M
6.
Nociceptive Sensory Neurons Mediate Inflammation Induced by Bacillus Anthracis Edema Toxin
Nicole J. Yang, Dylan V. Neel, Liwen Deng, Michelle Heyang, Angela Kennedy-Curran, Victoria S. Tong, Jin Mo Park, Isaac M. Chiu
Front Immunol. 2021; 12: 642373. Published online 2021 Aug 3. doi: 10.3389/fimmu.2021.642373
PMCID:
PMC8369925
AbstractArticlePDF–2.9M
7.
RP58 Represses Transcriptional Programs Linked to Nonneuronal Cell Identity and Glioblastoma Subtypes in Developing Neurons
Chaomei Xiang, Karla K. Frietze, Yingtao Bi, Yanwen Li, Valentina Dal Pozzo, Sharmistha Pal, Noah Alexander, Valerie Baubet, Victoria D’Acunto, Christopher E. Mason, Ramana V. Davuluri, Nadia Dahmane
Mol Cell Biol. 2021 Jul; 41(7): e00526-20. Prepublished online 2021 Apr 26. Published online 2021 Jun 23. doi: 10.1128/MCB.00526-20
PMCID:
PMC8315738
AbstractArticlePDF–7.7M
8.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
9.
Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each
Afzal M. Dogar, Ramona Pauchard-Batschulat, Barbara Grisoni-Neupert, Larry Richman, Alexandra Paillusson, Sylvain Pradervand, Otto Hagenbüchle, Giovanna Ambrosini, Christoph D. Schmid, Philipp Bucher, Lukas C. Kühn
PLoS One. 2018; 13(11): e0206823. Published online 2018 Nov 12. doi: 10.1371/journal.pone.0206823
PMCID:
PMC6231638
AbstractArticlePDF–3.8M
10.
CMG2/ANTXR2 regulates extracellular collagen VI which accumulates in hyaline fibromatosis syndrome
Jérôme Bürgi, Béatrice Kunz, Laurence Abrami, Julie Deuquet, Alessandra Piersigilli, Sabine Scholl-Bürgi, Ekkehart Lausch, Sheila Unger, Andrea Superti-Furga, Paolo Bonaldo, F. Gisou van der Goot
Nat Commun. 2017; 8: 15861. Published online 2017 Jun 12. doi: 10.1038/ncomms15861
PMCID:
PMC5472780
AbstractArticlePDF–5.7M
11.
Anthrax Toxin Protective Antigen Variants That Selectively Utilize either the CMG2 or TEM8 Receptors for Cellular Uptake and Tumor Targeting
Kuang-Hua Chen, Shihui Liu, Clinton E. Leysath, Sharmina Miller-Randolph, Yi Zhang, Rasem Fattah, Thomas H. Bugge, Stephen H. Leppla
J Biol Chem. 2016 Oct 14; 291(42): 22021–22029. Published online 2016 Aug 23. doi: 10.1074/jbc.M116.753301
PMCID:
PMC5063985
AbstractArticlePDF–338K
12.
Solid tumor therapy by selectively targeting stromal endothelial cells
Shihui Liu, Jie Liu, Qian Ma, Liu Cao, Rasem J. Fattah, Zuxi Yu, Thomas H. Bugge, Toren Finkel, Stephen H. Leppla
Proc Natl Acad Sci U S A. 2016 Jul 12; 113(28): E4079–E4087. Published online 2016 Jun 29. doi: 10.1073/pnas.1600982113
PMCID:
PMC4948345
AbstractArticlePDF–1.1M
13.
Targeted Silencing of Anthrax Toxin Receptors Protects against Anthrax Toxins
Maria T. Arévalo, Ashley Navarro, Chenoa D. Arico, Junwei Li, Omar Alkhatib, Shan Chen, Diana Diaz-Arévalo, Mingtao Zeng
J Biol Chem. 2014 May 30; 289(22): 15730–15738. Published online 2014 Apr 17. doi: 10.1074/jbc.M113.538587
PMCID:
PMC4140927
AbstractArticlePDF–1.1M
14.
Key tissue targets responsible for anthrax toxin-induced-lethality
Shihui Liu, Yi Zhang, Mahtab Moayeri, Jie Liu, Devorah Crown, Rasem Fattah, Alexander N. Wein, Zu-Xi Yu, Toren Finkel, Stephen H. Leppla
Nature. Author manuscript; available in PMC 2014 Sep 5.
Published in final edited form as: Nature. 2013 Sep 5; 501(7465): 63–68. Published online 2013 Aug 28. doi: 10.1038/nature12510
PMCID:
PMC4080305
AbstractArticlePDF–2.6M
15.
CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells
Louise H. Slater, Erik C. Hett, Anne E. Clatworthy, Kevin G. Mark, Deborah T. Hung
Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24): 9932–9937. Published online 2013 May 28. doi: 10.1073/pnas.1302257110
PMCID:
PMC3683768
AbstractArticlePDF–488K
16.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
17.
Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration
Stephen Lumayag, Caroline E. Haldin, Nicola J. Corbett, Karl J. Wahlin, Colleen Cowan, Sanja Turturro, Peter E. Larsen, Beatrix Kovacs, P. Dane Witmer, David Valle, Donald J. Zack, Daniel A. Nicholson, Shunbin Xu
Proc Natl Acad Sci U S A. 2013 Feb 5; 110(6): E507–E516. Published online 2013 Jan 22. doi: 10.1073/pnas.1212655110
PMCID:
PMC3568372
AbstractArticlePDF–2.1M
18.
Capillary morphogenesis protein-2 is required for mouse parturition by maintaining uterine collagen homeostasis
Diane E. Peters, Yi Zhang, Alfredo A. Molinolo, Sharmina Miller-Randolph, Roman Szabo, Thomas H. Bugge, Stephen H. Leppla, Shihui Liu
Biochem Biophys Res Commun. Author manuscript; available in PMC 2013 Jun 8.
Published in final edited form as: Biochem Biophys Res Commun. 2012 Jun 8; 422(3): 393–397. Published online 2012 May 7. doi: 10.1016/j.bbrc.2012.04.160
PMCID:
PMC3376708
AbstractArticlePDF–2.0M
19.
Anthrax Toxin Receptor 2 Functions in ECM Homeostasis of the Murine Reproductive Tract and Promotes MMP Activity
Claire V. Reeves, Xing Wang, Pelisa C. Charles-Horvath, Joy Y. Vink, Valeriya Y. Borisenko, John A. T. Young, Jan K. Kitajewski
PLoS One. 2012; 7(4): e34862. Published online 2012 Apr 17. doi: 10.1371/journal.pone.0034862
PMCID:
PMC3328497
AbstractArticlePDF–8.7M
20.
Anthrax Edema Toxin Impairs Clearance in Mice
Inka Sastalla, Shixing Tang, Devorah Crown, Shihui Liu, Michael A. Eckhaus, Indira K. Hewlett, Stephen H. Leppla, Mahtab Moayeri
Infect Immun. 2012 Feb; 80(2): 529–538. doi: 10.1128/IAI.05947-11
PMCID:
PMC3264307
AbstractArticlePDF–2.1M

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