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Items: 1 to 20 of 27

1.
Floxed Il1rl2 Locus with mCherry Reporter Element Reveals Distinct Expression Patterns of the IL-36 Receptor in Barrier Tissues
Nopprarat Tongmuang, Kathy Q. Cai, Jiahui An, Mariah Novy, Liselotte E. Jensen
Cells. 2024 May; 13(9): 787. Published online 2024 May 6. doi: 10.3390/cells13090787
PMCID:
PMC11083296
AbstractArticlePDF–21M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Interleukin‐38 promotes skin tumorigenesis in an IL‐1Rrp2‐dependent manner
Hong Zhou, Qixiang Zhao, Chengcheng Yue, Jiadong Yu, Huaping Zheng, Jing Hu, Zhonglan Hu, Haozhou Zhang, Xiu Teng, Xiao Liu, Xiaoqiong Wei, Yuxi Zhou, Fanlian Zeng, Yan Hao, Yawen Hu, Xiaoyan Wang, Chen Zhang, Linna Gu, Wenling Wu, Yifan Zhou, Kaijun Cui, Nongyu Huang, Wei Li, Zhen Wang, Jiong Li
EMBO Rep. 2022 Jun; 23(6): e53791. Published online 2022 May 17. doi: 10.15252/embr.202153791
PMCID:
PMC9171418
AbstractArticlePDF–3.6M
4.
Bacteria Induce Skin Regeneration via IL-1β Signaling
Gaofeng Wang, Evan Sweren, Haiyun Liu, Eric Wier, Martin P. Alphonse, Ruosi Chen, Nasif Islam, Ang Li, Yingchao Xue, Junjie Chen, Seungman Park, Yun Chen, Sam Lee, Yu Wang, Saifeng Wang, Nate K. Archer, William Andrews, Maureen A. Kane, Erika Dare, Sashank K. Reddy, Zhiqi Hu, Elizabeth A. Grice, Lloyd S. Miller, Luis A. Garza
Cell Host Microbe. Author manuscript; available in PMC 2022 May 12.
Published in final edited form as: Cell Host Microbe. 2021 May 12; 29(5): 777–791.e6. Published online 2021 Apr 1. doi: 10.1016/j.chom.2021.03.003
PMCID:
PMC8122070
AbstractArticlePDF–3.1M
5.
IL-36R signaling integrates innate and adaptive immune-mediated protection against enteropathogenic bacteria
Vu L. Ngo, Hirohito Abo, Michal Kuczma, Edyta Szurek, Nora Moore, Oscar Medina-Contreras, Asma Nusrat, Didier Merlin, Andrew T. Gewirtz, Leszek Ignatowicz, Timothy L. Denning
Proc Natl Acad Sci U S A. 2020 Nov 3; 117(44): 27540–27548. Published online 2020 Oct 21. doi: 10.1073/pnas.2004484117
PMCID:
PMC7959549
AbstractArticlePDF–2.2M
6.
Epicutaneous Staphylococcus aureus induces IL-36 to enhance IgE production and ensuing allergic disease
Garrett J. Patrick, Haiyun Liu, Martin P. Alphonse, Dustin A. Dikeman, Christine Youn, Jack C. Otterson, Yu Wang, Advaitaa Ravipati, Momina Mazhar, George Denny, Roger V. Ortines, Emily Zhang, Robert J. Miller, Carly A. Dillen, Qi Liu, Sabrina J. Nolan, Kristine Nguyen, LeeAnn Marcello, Danh C. Do, Eric M. Wier, Yan Zhang, Gary Caviness, Alexander C. Klimowicz, Diane V. Mierz, Jay S. Fine, Guangping Sun, Raphaela Goldbach-Mansky, Alina I. Marusina, Alexander A. Merleev, Emanual Maverakis, Luis A. Garza, Joshua D. Milner, Peisong Gao, Meera Ramanujam, Ernest L. Raymond, Nathan K. Archer, Lloyd S. Miller
J Clin Invest. 2021 Mar 1; 131(5): e143334. Published online 2021 Mar 1. doi: 10.1172/JCI143334
PMCID:
PMC7919715
AbstractArticlePDF–9.0M
7.
IL-36 signaling in keratinocytes controls early IL-23 production in psoriasis-like dermatitis
Jérémie D Goldstein, Esen Y Bassoy, Assunta Caruso, Jennifer Palomo, Emiliana Rodriguez, Sylvain Lemeille, Cem Gabay
Life Sci Alliance. 2020 Jun; 3(6): e202000688. Published online 2020 Apr 28. doi: 10.26508/lsa.202000688
PMCID:
PMC7190273
AbstractArticlePDF–2.7M
8.
TGF-β type 2 receptor–mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis
Tieshi Li, Susan Chubinskaya, Alessandra Esposito, Xin Jin, Lidia Tagliafierro, Richard Loeser, Arnavaz A. Hakimiyan, Lara Longobardi, Huseyin Ozkan, Anna Spagnoli
Sci Transl Med. Author manuscript; available in PMC 2020 May 8.
Published in final edited form as: Sci Transl Med. 2019 May 8; 11(491): eaan2585. doi: 10.1126/scitranslmed.aan2585
PMCID:
PMC7102613
AbstractArticlePDF–3.5M
9.
Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL‐1β
Christian Schwartz, Tara Moran, Sean P. Saunders, Agnieszka Kaszlikowska, Achilleas Floudas, Joana Bom, Gabriel Nunez, Yoichiro Iwakura, Luke O’Neill, Alan D. Irvine, Andrew N. J. McKenzie, Graham Ogg, Patrick T. Walsh, Jocelyne Demengeot, Padraic G. Fallon
Allergy. 2019 Oct; 74(10): 1920–1933. Published online 2019 Apr 29. doi: 10.1111/all.13801
PMCID:
PMC6850072
AbstractArticlePDF–1.5M
10.
Interleukin-36 cytokines alter the intestinal microbiome and can protect against obesity and metabolic dysfunction
Eirini Giannoudaki, Yasmina E. Hernandez-Santana, Kelly Mulfaul, Sarah L. Doyle, Emily Hams, Padraic G. Fallon, Arimin Mat, Donal O’Shea, Manfred Kopf, Andrew E. Hogan, Patrick T. Walsh
Nat Commun. 2019; 10: 4003. Published online 2019 Sep 5. doi: 10.1038/s41467-019-11944-w
PMCID:
PMC6728358
AbstractArticlePDF–7.4M
11.
A cytokine network involving IL-36γ, IL-23, and IL-22 promotes antimicrobial defense and recovery from intestinal barrier damage
Vu L. Ngo, Hirohito Abo, Estera Maxim, Akihito Harusato, Duke Geem, Oscar Medina-Contreras, Didier Merlin, Andrew T. Gewirtz, Asma Nusrat, Timothy L. Denning
Proc Natl Acad Sci U S A. 2018 May 29; 115(22): E5076–E5085. Published online 2018 May 14. doi: 10.1073/pnas.1718902115
PMCID:
PMC5984499
AbstractArticlePDF–1.8M
12.
Staphylococcus aureus epicutaneous exposure drives skin inflammation via IL-36-mediated T cell responses
Haiyun Liu, Nathan K. Archer, Carly A. Dillen, Yu Wang, Alyssa G. Ashbaugh, Roger V. Ortines, Tracy Kao, Steven K. Lee, Shuting S. Cai, Robert J. Miller, Mark C. Marchitto, Emily Zhang, Daniel P. Riggins, Roger D. Plaut, Scott Stibitz, Raif S. Geha, Lloyd S. Miller
Cell Host Microbe. Author manuscript; available in PMC 2018 Nov 8.
Published in final edited form as: Cell Host Microbe. 2017 Nov 8; 22(5): 653–666.e5. doi: 10.1016/j.chom.2017.10.006
PMCID:
PMC5774218
AbstractArticlePDF–2.1M
13.
IL-36? signaling controls the induced regulatory T cell – TH9 cell balance via NF?B activation and STAT transcription factors
Akihito Harusato, Hirohito Abo, Vu Le Ngo, Samuel Won-zu Yi, Kazunori Mitsutake, Satoru Osuka, Jacob E. Kohlmeier, Jian-Dong Li, Andrew T. Gewirtz, Asma Nusrat, Timothy L. Denning
Mucosal Immunol. Author manuscript; available in PMC 2017 Oct 18.
Published in final edited form as: Mucosal Immunol. 2017 Nov; 10(6): 1455–1467. Published online 2017 Mar 22. doi: 10.1038/mi.2017.21
PMCID:
PMC5610052
AbstractArticlePDF–1.9M
14.
IL-36γ is a crucial proximal component of protective type-1-mediated lung mucosal immunity in Gram-positive and -negative bacterial pneumonia
M A Kovach, B Singer, G Martinez-Colon, M W Newstead, X Zeng, P Mancuso, T A Moore, S L Kunkel, M Peters-Golden, B B Moore, T J Standiford
Mucosal Immunol. 2017 Sep; 10(5): 1320–1334. Published online 2017 Feb 8. doi: 10.1038/mi.2016.130
PMCID:
PMC5548659
AbstractArticlePDF–1.6M
15.
IL-36 Receptor Deletion Attenuates Lung Injury and Decreases Mortality in Murine Influenza Pneumonia
Tetsuji Aoyagi, Michael W. Newstead, Xianying Zeng, Steven L. Kunkel, Mitsuo Kaku, Theodore J. Standiford
Mucosal Immunol. Author manuscript; available in PMC 2017 Jun 19.
Published in final edited form as: Mucosal Immunol. 2017 Jul; 10(4): 1043–1055. Published online 2016 Dec 14. doi: 10.1038/mi.2016.107
PMCID:
PMC5471142
AbstractArticlePDF–2.8M
16.
IL-36 receptor promotes resolution of intestinal damage
Oscar Medina-Contreras, Akihito Harusato, Hikaru Nishio, Kyle L. Flannigan, Vu Ngo, Giovanna Leoni, Philipp-Alexander Neumann, Duke Geem, Loukia N. Lili, Ravisankar A. Ramadas, Benoit Chassaing, Andrew T. Gewirtz, Jacob E. Kohlmeier, Charles A. Parkos, Jennifer E. Towne, Asma Nusrat, Timothy L. Denning
J Immunol. Author manuscript; available in PMC 2017 Jan 1.
Published in final edited form as: J Immunol. 2016 Jan 1; 196(1): 34–38. Published online 2015 Nov 20. doi: 10.4049/jimmunol.1501312
PMCID:
PMC4684965
AbstractArticlePDF–1.2M
17.
Interleukin-36γ is expressed by neutrophils and can activate microglia, but has no role in experimental autoimmune encephalomyelitis
Lusine Bozoyan, Aline Dumas, Alexandre Patenaude, Luc Vallières
J Neuroinflammation. 2015; 12: 173. Published online 2015 Sep 17. doi: 10.1186/s12974-015-0392-7
PMCID:
PMC4574267
AbstractArticlePDF–2.4M
18.
IL-36γ transforms the tumor microenvironment and promotes type 1 lymphocyte-mediated antitumor immune responses
Xuefeng Wang, Xin Zhao, Chao Feng, Aliyah Weinstein, Rui Xia, Wen Wen, Quansheng Lv, Shuting Zuo, Peijun Tang, Xi Yang, Xiaojuan Chen, Hongrui Wang, Shayang Zang, Lindsay Stollings, Timothy L. Denning, Jingting Jiang, Jie Fan, Guangbo Zhang, Xueguang Zhang, Yibei Zhu, Walter Storkus, Binfeng Lu
Cancer Cell. Author manuscript; available in PMC 2016 Sep 14.
Published in final edited form as: Cancer Cell. 2015 Sep 14; 28(3): 296–306. Published online 2015 Aug 27. doi: 10.1016/j.ccell.2015.07.014
PMCID:
PMC4573903
AbstractArticlePDF–3.5M
19.
Psoriasiform dermatitis is driven by IL-36–mediated DC-keratinocyte crosstalk
Luigi Tortola, Esther Rosenwald, Brian Abel, Hal Blumberg, Matthias Schäfer, Anthony J. Coyle, Jean-Christoph Renauld, Sabine Werner, Jan Kisielow, Manfred Kopf
J Clin Invest. 2012 Nov 1; 122(11): 3965–3976. Published online 2012 Oct 15. doi: 10.1172/JCI63451
PMCID:
PMC3484446
AbstractArticlePDF–2.7M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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