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Items: 1 to 20 of 62

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Elevated IgE from attenuated CARD11 signaling: lessons from atopic mice and humans
Joel L Pomerantz, Joshua D Milner, Andrew L Snow
Curr Opin Immunol. Author manuscript; available in PMC 2023 Aug 14.
Published in final edited form as: Curr Opin Immunol. 2022 Dec; 79: 102255. Published online 2022 Nov 2. doi: 10.1016/j.coi.2022.102255
PMCID:
PMC10424059
AbstractArticlePDF–512K
3.
CARD11 gain-of-function mutation drives cell-autonomous accumulation of PD-1+ ICOShigh activated T cells, T-follicular, T-regulatory and T-follicular regulatory cells
Etienne Masle-Farquhar, Yogesh Jeelall, Jacqueline White, Julia Bier, Elissa K. Deenick, Robert Brink, Keisuke Horikawa, Christopher Carl Goodnow
Front Immunol. 2023; 14: 1095257. Published online 2023 Mar 7. doi: 10.3389/fimmu.2023.1095257
PMCID:
PMC10028194
AbstractArticlePDF–9.1M
4.
CARD11 mutation and HBZ expression induce lymphoproliferative disease and adult T-cell leukemia/lymphoma
Takuro Kameda, Kotaro Shide, Ayako Kamiunten, Yasunori Kogure, Daisuke Morishita, Junji Koya, Yuki Tahira, Keiichi Akizuki, Takako Yokomizo-Nakano, Sho Kubota, Kosuke Marutsuka, Masaaki Sekine, Tomonori Hidaka, Yoko Kubuki, Yuichi Kitai, Tadashi Matsuda, Akinori Yoda, Takayuki Ohshima, Midori Sugiyama, Goro Sashida, Keisuke Kataoka, Seishi Ogawa, Kazuya Shimoda
Commun Biol. 2022; 5: 1309. Published online 2022 Nov 29. doi: 10.1038/s42003-022-04284-x
PMCID:
PMC9709164
AbstractArticlePDF–5.1M
5.
Gene body methylation of the lymphocyte-specific gene CARD11 results in its overexpression and regulates cancer mTOR signaling
Michael H. McGuire, Santosh K. Dasari, Hui Yao, Yunfei Wen, Lingegowda S. Mangala, Emine Bayraktar, Wencai Ma, Cristina Ivan, Einav Shoshan, Sherry Y. Wu, Eric Jonasch, Menashe Bar-Eli, Jing Wang, Keith A. Baggerly, Anil K. Sood
Mol Cancer Res. Author manuscript; available in PMC 2022 May 1.
Published in final edited form as: Mol Cancer Res. 2021 Nov; 19(11): 1917–1928. Published online 2021 Aug 4. doi: 10.1158/1541-7786.MCR-20-0753
PMCID:
PMC8568653
AbstractArticlePDF–830K
6.
Pathway-specific Defects in T, B, and NK cells and Age-dependent Development of High IgE in Mice Heterozygous for a CADINS-associated Dominant Negative CARD11 Allele
Shelby M. Hutcherson, Jacquelyn R. Bedsaul, Joel L. Pomerantz
J Immunol. Author manuscript; available in PMC 2022 Aug 15.
Published in final edited form as: J Immunol. 2021 Aug 15; 207(4): 1150–1164. Published online 2021 Aug 2. doi: 10.4049/jimmunol.2001233
PMCID:
PMC8355193
AbstractArticlePDF–2.2M
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
8.
Coordinated regulation of scaffold opening and enzymatic activity during CARD11 signaling
Zhaoquan Wang, Shelby M. Hutcherson, Chao Yang, Rakhi P. Jattani, Julia M. Tritapoe, Yong-Kang Yang, Joel L. Pomerantz
J Biol Chem. 2019 Oct 4; 294(40): 14648–14660. Published online 2019 Aug 7. doi: 10.1074/jbc.RA119.009551
PMCID:
PMC6779434
AbstractArticlePDF–3.3M
9.
Targeting the CBM complex causes Treg cells to prime tumors for immune checkpoint therapy
Mauro Di Pilato, Edward Y. Kim, Bruno L. Cadilha, Jasper N. Pruessmann, Mazen N. Nasrallah, Davide Seruggia, Shariq M. Usmani, Sandra Misale, Valentina Zappulli, Esteban Carrizosa, Vinidhra Mani, Matteo Ligorio, Ross D. Warner, Benjamin D. Medoff, Francesco Marangoni, Alexandra-Chloe Villani, Thorsten R. Mempel
Nature. Author manuscript; available in PMC 2019 Nov 15.
Published in final edited form as: Nature. 2019 Jun; 570(7759): 112–116. Published online 2019 May 15. doi: 10.1038/s41586-019-1215-2
PMCID:
PMC6656391
AbstractArticlePDF–2.4M
10.
Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells
Marc Rosenbaum, Andreas Gewies, Konstanze Pechloff, Christoph Heuser, Thomas Engleitner, Torben Gehring, Lara Hartjes, Sabrina Krebs, Daniel Krappmann, Mark Kriegsmann, Wilko Weichert, Roland Rad, Christian Kurts, Jürgen Ruland
Nat Commun. 2019; 10: 2352. Published online 2019 May 28. doi: 10.1038/s41467-019-10203-2
PMCID:
PMC6538646
AbstractArticlePDF–2.0M
11.
Activated CARD11 accelerates germinal center kinetics, promoting mTORC1 and terminal differentiation
Michelle N. Wray-Dutra, Raghav Chawla, Kerri R. Thomas, Brenda J. Seymour, Tanvi Arkatkar, Karen M. Sommer, Socheath Khim, Cole Trapnell, Richard G. James, David J. Rawlings
J Exp Med. 2018 Sep 3; 215(9): 2445–2461. doi: 10.1084/jem.20180230
PMCID:
PMC6122963
AbstractArticlePDF–2.9M
12.
Role of IκB Kinase β in Regulating the Remodeling of the CARMA1-Bcl10-MALT1 Complex
Zubair A. Karim, Nicole R. Hensch, Hanan Qasim, Fatima Z. Alshbool, Fadi T. Khasawneh
Biochem Biophys Res Commun. Author manuscript; available in PMC 2019 Jun 2.
Published in final edited form as: Biochem Biophys Res Commun. 2018 Jun 2; 500(2): 268–274. Published online 2018 Apr 14. doi: 10.1016/j.bbrc.2018.04.057
PMCID:
PMC5928781
AbstractArticlePDF–631K
13.
Activation of the Transcription Factor c-Maf in T Cells Is Dependent on the CARMA1-IKKβ Signaling Cascade
Marzenna Blonska, Donghyun Joo, Roza I. Nurieva, Xueqiang Zhao, Paul Chiao, Shao-Cong Sun, Chen Dong, Xin Lin
Sci Signal. Author manuscript; available in PMC 2018 Jan 10.
Published in final edited form as: Sci Signal. 2013 Dec 17; 6(306): ra110. Published online 2013 Dec 17. doi: 10.1126/scisignal.2004273
PMCID:
PMC5762115
AbstractArticlePDF–1.4M
14.
IL-2 prevents deletion of developing T-regulatory cells in the thymus
Daniel Y Hu, Rushika C Wirasinha, Christopher C Goodnow, Stephen R Daley
Cell Death Differ. 2017 Jun; 24(6): 1007–1016. Published online 2017 May 12. doi: 10.1038/cdd.2017.38
PMCID:
PMC5442470
AbstractArticlePDF–2.7M
15.
Synergistic activity of Card11 mutant and Bcl6 in the development of diffuse large B‐cell lymphoma in a mouse model
Taishi Takahara, Keitaro Matsuo, Masao Seto, Shigeo Nakamura, Shinobu Tsuzuki
Cancer Sci. 2016 Nov; 107(11): 1572–1580. Published online 2016 Nov 4. doi: 10.1111/cas.13057
PMCID:
PMC5132338
AbstractArticlePDF–911K
16.
LRRK1 is critical in the regulation of B-cell responses and CARMA1-dependent NF-κB activation
Keiko Morimoto, Yoshihiro Baba, Hisaaki Shinohara, Sujin Kang, Satoshi Nojima, Tetsuya Kimura, Daisuke Ito, Yuji Yoshida, Yohei Maeda, Hana Sarashina-Kida, Masayuki Nishide, Takashi Hosokawa, Yasuhiro Kato, Yoshitomo Hayama, Yuhei Kinehara, Tatsusada Okuno, Hyota Takamatsu, Toru Hirano, Yoshihito Shima, Masashi Narazaki, Tomohiro Kurosaki, Toshihiko Toyofuku, Atsushi Kumanogoh
Sci Rep. 2016; 6: 25738. Published online 2016 May 11. doi: 10.1038/srep25738
PMCID:
PMC4863158
AbstractArticlePDF–1.7M
17.
Caspase-8 and c-FLIPL Associate in Lipid Rafts with NF-κB Adaptors during T Cell Activation
Ravi S. Misra, Jennifer Q. Russell, Andreas Koenig, Jennifer A. Hinshaw-Makepeace, Renren Wen, Demin Wang, Hairong Huo, Dan R. Littman, Uta Ferch, Jurgen Ruland, Margot Thome, Ralph C. Budd
J Biol Chem. Author manuscript; available in PMC 2015 Jul 31.
Published in final edited form as: J Biol Chem. 2007 Jul 6; 282(27): 19365–19374. Published online 2007 Apr 26. doi: 10.1074/jbc.M610610200
PMCID:
PMC4521413
AbstractArticlePDF–1009K
18.
Bringing Statistics Up to Speed with Data in Analysis of Lymphocyte Motility
Kenneth Letendre, Emmanuel Donnadieu, Melanie E. Moses, Judy L. Cannon
PLoS One. 2015; 10(5): e0126333. Published online 2015 May 14. doi: 10.1371/journal.pone.0126333
PMCID:
PMC4431811
AbstractArticlePDF–1.1M
19.
A Carma1/MALT1-dependent, Bcl10-independent, pathway regulates antigen receptor-mediated mTOR signaling in T cells
Kristia S. Hamilton, Binh Phong, Catherine Corey, Jing Cheng, Balachandra Gorentla, Xiaoping Zhong, Sruti Shiva, Lawrence P. Kane
Sci Signal. Author manuscript; available in PMC 2015 Apr 21.
Published in final edited form as: Sci Signal. 2014; 7(329): ra55. Published online 2014 Jun 10. doi: 10.1126/scisignal.2005169
PMCID:
PMC4405131
AbstractArticlePDF–1.8M
20.
Regulation of T-cell activation and migration by the kinase TBK1 during neuroinflammation
Jiayi Yu, Xiaofei Zhou, Mikyoung Chang, Mako Nakaya, Jae-Hoon Chang, Yichuan Xiao, J. William Lindsey, Stephanie Dorta-Estremera, Wei Cao, Anna Zal, Tomasz Zal, Shao-Cong Sun
Nat Commun. 2015 Jan 21; 6: 6074. Published online 2015 Jan 21. doi: 10.1038/ncomms7074
PMCID:
PMC4302769
AbstractArticlePDF–1.5M

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