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Select item 91052361.

Hippocampal Excitatory Synaptic Transmission and Plasticity Are Differentially Altered during Postnatal Development by Loss of the X-Linked Intellectual Disability Protein Oligophrenin-1

Noemie Cresto, Nicolas Lebrun, Florent Dumont, Franck Letourneur, Pierre Billuart, Nathalie Rouach

Cells. 2022 May; 11(9): 1545. Published online 2022 May 5. doi: 10.3390/cells11091545

PMCID:: PMC9105236

Abstract Article PDF–9.5M

Select item 86003972.

Androgen deprivation-induced OPHN1 amplification promotes castration-resistant prostate cancer

Junjiang Liu, Yunxia Zhang, Shoubin Li, Fuzhen Sun, Gang Wang, Dong Wei, Tao Yang, Shouyi Gu

Oncol Rep. 2022 Jan; 47(1): 3. Published online 2021 Nov 2. doi: 10.3892/or.2021.8214

PMCID:: PMC8600397

Abstract Article PDF–1.1M

Select item 83132393.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 81410444.

Oligophrenin-1 Moderates Behavioral Responses to Stress by Regulating Parvalbumin Interneuron Activity in the Medial Prefrontal Cortex

Minghui Wang, Nicholas B. Gallo, Yilin Tai, Bo Li, Linda Van Aelst

Neuron. Author manuscript; available in PMC 2022 May 19.

Published in final edited form as: Neuron. 2021 May 19; 109(10): 1636–1656.e8. Published online 2021 Apr 7. doi: 10.1016/j.neuron.2021.03.016

PMCID:: PMC8141044

Abstract Article PDF–3.6M

Select item 79387705.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78127496.

Altered Cl⁻ homeostasis hinders forebrain GABAergic interneuron migration in a mouse model of intellectual disability

Andrea Maset, Luisa Galla, Simona Francia, Olga Cozzolino, Paola Capasso, Rosa Chiara Goisis, Gabriele Losi, Angelo Lombardo, Gian Michele Ratto, Claudia Lodovichi

Proc Natl Acad Sci U S A. 2021 Jan 12; 118(2): e2016034118. Published online 2020 Dec 29. doi: 10.1073/pnas.2016034118

PMCID:: PMC7812749

Abstract Article PDF–2.9M

Select item 66927707.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Abstract Article PDF–7.7M

Select item 66731148.

Loss of X-Linked Mental Retardation Gene Oligophrenin1 in Mice Impairs Spatial Memory and Leads to Ventricular Enlargement and Dendritic Spine Immaturity

Malik Khelfaoui, Cécile Denis, Elly van Galen, Frédéric de Bock, Alain Schmitt, Christophe Houbron, Elise Morice, Bruno Giros, Ger Ramakers, Laurent Fagni, Jamel Chelly, Marika Nosten-Bertrand, Pierre Billuart

J Neurosci. 2007 Aug 29; 27(35): 9439–9450. doi: 10.1523/JNEUROSCI.2029-07.2007

PMCID:: PMC6673114

Abstract Article PDF–8.1M

Select item 66052749.

Oligophrenin-1 Connects Exocytotic Fusion to Compensatory Endocytosis in Neuroendocrine Cells

Sébastien Houy, Catherine Estay-Ahumada, Pauline Croisé, Valérie Calco, Anne-Marie Haeberlé, Yannick Bailly, Pierre Billuart, Nicolas Vitale, Marie-France Bader, Stéphane Ory, Stéphane Gasman

J Neurosci. 2015 Aug 5; 35(31): 11045–11055. doi: 10.1523/JNEUROSCI.4048-14.2015

PMCID:: PMC6605274

Abstract Article PDF–1.5M

Select item 659680710.

Protein Kinase A Deregulation in the Medial Prefrontal Cortex Impairs Working Memory in Murine Oligophrenin-1 Deficiency

Chun-Lei Zhang, Mattia Aime, Emilie Laheranne, Xander Houbaert, Hajer El Oussini, Christelle Martin, Marilyn Lepleux, Elisabeth Normand, Jamel Chelly, Etienne Herzog, Pierre Billuart, Yann Humeau

J Neurosci. 2017 Nov 15; 37(46): 11114–11126. doi: 10.1523/JNEUROSCI.0351-17.2017

PMCID:: PMC6596807

Abstract Article PDF–3.4M

Select item 534607111.

Pharmacological rescue of adult hippocampal neurogenesis in a mouse model of X-linked intellectual disability

Manuela Allegra, Cristina Spalletti, Beatrice Vignoli, Stefano Azzimondi, Irene Busti, Pierre Billuart, Marco Canossa, Matteo Caleo

Neurobiol Dis. 2017 Apr; 100: 75–86. doi: 10.1016/j.nbd.2017.01.003

PMCID:: PMC5346071

Abstract Article

Select item 448439212.

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders

Heather Fairfield, Anuj Srivastava, Guruprasad Ananda, Rangjiao Liu, Martin Kircher, Anuradha Lakshminarayana, Belinda S. Harris, Son Yong Karst, Louise A. Dionne, Coleen C. Kane, Michelle Curtain, Melissa L. Berry, Patricia F. Ward-Bailey, Ian Greenstein, Candice Byers, Anne Czechanski, Jocelyn Sharp, Kristina Palmer, Polyxeni Gudis, Whitney Martin, Abby Tadenev, Laurent Bogdanik, C. Herbert Pratt, Bo Chang, David G. Schroeder, Gregory A. Cox, Paul Cliften, Jeffrey Milbrandt, Stephen Murray, Robert Burgess, David E. Bergstrom, Leah Rae Donahue, Hanan Hamamy, Amira Masri, Federico A. Santoni, Periklis Makrythanasis, Stylianos E. Antonarakis, Jay Shendure, Laura G. Reinholdt

Genome Res. 2015 Jul; 25(7): 948–957. doi: 10.1101/gr.186882.114

PMCID:: PMC4484392

Abstract Article PDF–604K

Select item 401172713.

Reduced Gamma Oscillations in a Mouse Model of Intellectual Disability: A Role for Impaired Repetitive Neurotransmission?

Andrew D. Powell, Pierre-Philippe Saintot, Kalbinder K. Gill, Ashtami Bharathan, S. Caroline Buck, Gareth Morris, Premysl Jiruska, John G. R. Jefferys

PLoS One. 2014; 9(5): e95871. Published online 2014 May 6. doi: 10.1371/journal.pone.0095871

PMCID:: PMC4011727

Abstract Article PDF–1.4M

Select item 401049514.

Treadmill Exercise Induces Neutrophil Recruitment into Muscle Tissue in a Reactive Oxygen Species-Dependent Manner. An Intravital Microscopy Study

Albená Nunes-Silva, Priscila T. T. Bernardes, Bárbara M. Rezende, Fernando Lopes, Elisa C. Gomes, Pedro E. Marques, Paulo M. A. Lima, Cândido C. Coimbra, Gustavo B. Menezes, Mauro M. Teixeira, Vanessa Pinho

PLoS One. 2014; 9(5): e96464. Published online 2014 May 5. doi: 10.1371/journal.pone.0096464

PMCID:: PMC4010495

Abstract Article PDF–2.8M

Select item 357241015.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163