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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107193422.

Sex-dimorphic neuroprotective effect of CD163 in an α-synuclein mouse model of Parkinson’s disease

Sara A. Ferreira, Conghui Li, Ida H. Klæstrup, Zagorka Vitic, Rikke K. Rasmussen, Asger Kirkegaard, Gitte U. Toft, Cristine Betzer, Pia Svendsen, Poul H. Jensen, Yonglun Luo, Anders Etzerodt, Søren K. Moestrup, Marina Romero-Ramos

NPJ Parkinsons Dis. 2023; 9: 164. Published online 2023 Dec 13. doi: 10.1038/s41531-023-00606-w

PMCID:: PMC10719342

Abstract Article PDF–16M

Select item 106175783.

Ectopic expression of murine CD163 enables cell-culture isolation of lactate dehydrogenase-elevating virus 63 years after its discovery

Teressa M. Shaw, Sara M. Maloney, Kylie Nennig, Mitchell D. Ramuta, Andrew Norton, Rodrigo Ibarra, Paul Kuehnert, Margo Brinton, Kay Faaberg, Jens H. Kuhn, David H. O'Connor, Cody J. Warren, Adam L. Bailey

J Virol. 2023 Oct; 97(10): e00930-23. Published online 2023 Oct 4. doi: 10.1128/jvi.00930-23

PMCID:: PMC10617578

Abstract Article PDF–2.7M

Select item 94971504.

Comparison of Muscle Regeneration after BMSC-Conditioned Medium, Syngeneic, or Allogeneic BMSC Injection

Barbara Świerczek-Lasek, Lukasz Tolak, Lukasz Bijoch, Marzena Stefaniuk, Patrycja Szpak, Ilona Kalaszczynska, Władysława Streminska, Maria A. Ciemerych, Karolina Archacka

Cells. 2022 Sep; 11(18): 2843. Published online 2022 Sep 12. doi: 10.3390/cells11182843

PMCID:: PMC9497150

Abstract Article PDF–2.2M

Select item 89566265.

Kinetics of LYVE-1-positive M2-like macrophages in developing and repairing dental pulp in vivo and their pro-angiogenic activity in vitro

Thoai Quoc Kieu, Kento Tazawa, Nobuyuki Kawashima, Sonoko Noda, Mayuko Fujii, Keisuke Nara, Kentaro Hashimoto, Peifeng Han, Takashi Okiji

Sci Rep. 2022; 12: 5176. Published online 2022 Mar 25. doi: 10.1038/s41598-022-08987-3

PMCID:: PMC8956626

Abstract Article PDF–7.6M

Select item 75667166.

IsdB antibody–mediated sepsis following S. aureus surgical site infection

Kohei Nishitani, Masahiro Ishikawa, Yugo Morita, Noriaki Yokogawa, Chao Xie, Karen L. de Mesy Bentley, Hiromu Ito, Stephen L. Kates, John L. Daiss, Edward M. Schwarz

JCI Insight. 2020 Oct 2; 5(19): e141164. Published online 2020 Oct 2. doi: 10.1172/jci.insight.141164

PMCID:: PMC7566716

Abstract Article PDF–38M

Select item 75189577.

CD163 deficiency facilitates lipopolysaccharide‐induced inflammatory responses and endotoxin shock in mice

Yukio Fujiwara, Koji Ohnishi, Hasita Horlad, Yoichi Saito, Daisuke Shiraishi, Hiroto Takeya, Daiki Yoshii, Shinjiro Kaieda, Tomoaki Hoshino, Yoshihiro Komohara

Clin Transl Immunology. 2020; 9(9): e1162. Published online 2020 Sep 25. doi: 10.1002/cti2.1162

PMCID:: PMC7518957

Abstract Article PDF–3.9M

Select item 73824598.

Mouse CD163 deficiency strongly enhances experimental collagen-induced arthritis

Pia Svendsen, Anders Etzerodt, Bent W. Deleuran, Søren K. Moestrup

Sci Rep. 2020; 10: 12447. Published online 2020 Jul 24. doi: 10.1038/s41598-020-69018-7

PMCID:: PMC7382459

Abstract Article PDF–1.6M

Select item 59510159.

The absence of the CD163 receptor has distinct temporal influences on intracerebral hemorrhage outcomes

Jenna L Leclerc, Andrew S Lampert, Claudia Loyola Amador, Brandon Schlakman, Terrie Vasilopoulos, Pia Svendsen, Søren K Moestrup, Sylvain Doré

J Cereb Blood Flow Metab. 2018 Feb; 38(2): 262–273. Published online 2017 Mar 30. doi: 10.1177/0271678X17701459

PMCID:: PMC5951015

Abstract Article PDF–1.6M

Select item 582487310.

CD163⁺ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis

Liang Guo, Hirokuni Akahori, Emanuel Harari, Samantha L. Smith, Rohini Polavarapu, Vinit Karmali, Fumiyuki Otsuka, Rachel L. Gannon, Ryan E. Braumann, Megan H. Dickinson, Anuj Gupta, Audrey L. Jenkins, Michael J. Lipinski, Johoon Kim, Peter Chhour, Paul S. de Vries, Hiroyuki Jinnouchi, Robert Kutys, Hiroyoshi Mori, Matthew D. Kutyna, Sho Torii, Atsushi Sakamoto, Cheol Ung Choi, Qi Cheng, Megan L. Grove, Mariem A. Sawan, Yin Zhang, Yihai Cao, Frank D. Kolodgie, David P. Cormode, Dan E. Arking, Eric Boerwinkle, Alanna C. Morrison, Jeanette Erdmann, Nona Sotoodehnia, Renu Virmani, Aloke V. Finn

J Clin Invest. 2018 Mar 1; 128(3): 1106–1124. Published online 2018 Feb 19. doi: 10.1172/JCI93025

PMCID:: PMC5824873

Abstract Article PDF–22M

Select item 547778211.

The haptoglobin beta subunit sequesters HMGB1 toxicity in sterile and infectious inflammation

Huan Yang, Haichao Wang, Yongjun Wang, Meghan Addorisio, Jianhua Li, Michael J. Postiglione, Sangeeta S. Chavan, Yousef Al-Abed, Daniel J. Antoine, Ulf Andersson, Kevin J. Tracey

J Intern Med. Author manuscript; available in PMC 2018 Jul 1.

Published in final edited form as: J Intern Med. 2017 Jul; 282(1): 76–93. Published online 2017 May 31. doi: 10.1111/joim.12619

Expression of Concern in:: J Intern Med. 2019 Jul; 286(1): 115.

Correction in:: J Intern Med. 2020 May; 287(5): 585.

PMCID:: PMC5477782

Abstract Article PDF–1.9M

Select item 546774612.

Insensitivity of Astrocytes to Interleukin-10 Signaling following Peripheral Immune Challenge Results in Prolonged Microglial Activation in the Aged Brain

Diana M. Norden, Paige J. Trojanowski, Frederick R. Walker, Jonathan P. Godbout

Neurobiol Aging. Author manuscript; available in PMC 2017 Aug 1.

Published in final edited form as: Neurobiol Aging. 2016 Aug; 44: 22–41. Published online 2016 Apr 27. doi: 10.1016/j.neurobiolaging.2016.04.014

PMCID:: PMC5467746

Abstract Article PDF–2.0M

Select item 529582113.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 497021314.

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA

Xiaoyun Liu, Yan Jiao, Yanhong Cao, Nan Deng, Yonghui Ma, Karen A. Hasty, Andrew Kang, Hong Chen, John M. Stuart, Weikuan Gu

BMC Immunol. 2016; 17: 25. Published online 2016 Aug 2. doi: 10.1186/s12865-016-0163-y

PMCID:: PMC4970213

Abstract Article PDF–2.5M

Select item 491831015.

CD163 interacts with TWEAK to regulate tissue regeneration after ischaemic injury

Hirokuni Akahori, Vinit Karmali, Rohini Polavarapu, Alicia N. Lyle, Daiana Weiss, Eric Shin, Ahsan Husain, Nawazish Naqvi, Richard Van Dam, Anwer Habib, Cheol Ung Choi, Adrienne L. King, Kimberly Pachura, W. Robert Taylor, David J. Lefer, Aloke V. Finn

Nat Commun. 2015; 6: 7792. Published online 2015 Aug 5. doi: 10.1038/ncomms8792

PMCID:: PMC4918310

Abstract Article PDF–2.6M

Select item 490217016.

Identification of CD163 as an antiinflammatory receptor for HMGB1-haptoglobin complexes

Huan Yang, Haichao Wang, Yaakov A. Levine, Manoj K. Gunasekaran, Yongjun Wang, Meghan Addorisio, Shu Zhu, Wei Li, Jianhua Li, Dominique P.V. de Kleijn, Peder S. Olofsson, H. Shaw Warren, Mingzhu He, Yousef Al-Abed, Jesse Roth, Daniel J. Antoine, Sangeeta S. Chavan, Ulf Andersson, Kevin J. Tracey

JCI Insight. 2016 May 19; 1(7): e85375. Published online 2016 May 19. doi: 10.1172/jci.insight.85375

Expression of Concern in:: JCI Insight. 2018 Dec 20; 3(24): e126616.

Correction in:: JCI Insight. 2018 Dec 20; 3(24): e126617.

PMCID:: PMC4902170

Abstract Article PDF–1.6M

Select item 479442817.

A CCL24-dependent Pathway Augments Eosinophilic Airway Inflammation in House Dust Mite-challenged Cd163^-/- Mice

Cuilian Dai, Xianglan Yao, Elizabeth M. Gordon, Amisha Barochia, Rosemarie A. Cuento, Maryann Kaler, Katharine S. Meyer, Karen J. Keeran, Gayle Z. Nugent, Kenneth R. Jeffries, Xuan Qu, Zu-Xi Yu, Angel Aponte, Marjan Gucek, Pradeep K. Dagur, J. Philip McCoy, Stewart J. Levine

Mucosal Immunol. Author manuscript; available in PMC 2016 May 18.

Published in final edited form as: Mucosal Immunol. 2016 May; 9(3): 702–717. Published online 2015 Sep 16. doi: 10.1038/mi.2015.94

PMCID:: PMC4794428

Abstract Article PDF–2.2M

Select item 396495518.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 388720419.

Structural Basis for Inflammation-driven Shedding of CD163 Ectodomain and Tumor Necrosis Factor-α in Macrophages

Anders Etzerodt, Mie Rostved Rasmussen, Pia Svendsen, Athena Chalaris, Jeanette Schwarz, Ian Galea, Holger Jon Møller, Søren Kragh Moestrup

J Biol Chem. 2014 Jan 10; 289(2): 778–788. Published online 2013 Nov 25. doi: 10.1074/jbc.M113.520213

PMCID:: PMC3887204

Abstract Article PDF–2.0M

Select item 343631320.

α₁-Acid Glycoprotein Up-regulates CD163 via TLR4/CD14 Protein Pathway: POSSIBLE PROTECTION AGAINST HEMOLYSIS-INDUCED OXIDATIVE STRESS

Hisakazu Komori, Hiroshi Watanabe, Tsuyoshi Shuto, Azusa Kodama, Hitoshi Maeda, Kenji Watanabe, Hirofumi Kai, Masaki Otagiri, Toru Maruyama

J Biol Chem. 2012 Aug 31; 287(36): 30688–30700. Published online 2012 Jul 17. doi: 10.1074/jbc.M112.353771

PMCID:: PMC3436313

Abstract Article PDF–1.7M

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