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Items: 1 to 20 of 150

1.
Hepcidin deficiency impairs hippocampal neurogenesis and mediates brain atrophy and memory decline in mice
Xue Bai, Bing Wang, Yiduo Cui, Siqi Tian, Yi Zhang, Linhao You, Yan-Zhong Chang, Guofen Gao
J Neuroinflammation. 2024; 21: 15. Published online 2024 Jan 9. doi: 10.1186/s12974-023-03008-0
PMCID:
PMC10777572
AbstractArticlePDF–8.2M
2.
A Decrease in Maternal Iron Levels Is the Predominant Factor Suppressing Hepcidin during Pregnancy in Mice
Sheridan L. Helman, Sarah J. Wilkins, Jennifer C. J. Chan, Gunter Hartel, Daniel F. Wallace, Gregory J. Anderson, David M. Frazer
Int J Mol Sci. 2023 Sep; 24(18): 14379. Published online 2023 Sep 21. doi: 10.3390/ijms241814379
PMCID:
PMC10532249
AbstractArticlePDF–2.0M
3.
Role of hepcidin upregulation and proteolytic cleavage of ferroportin 1 in hepatitis C virus-induced iron accumulation
Kazuyoshi Ohta, Masahiko Ito, Takeshi Chida, Kenji Nakashima, Satoshi Sakai, Yumi Kanegae, Hideya Kawasaki, Takuya Aoshima, Shuji Takabayashi, Hirotaka Takahashi, Kazuhito Kawata, Ikuo Shoji, Tatsuya Sawasaki, Takafumi Suda, Tetsuro Suzuki
PLoS Pathog. 2023 Aug; 19(8): e1011591. Published online 2023 Aug 16. doi: 10.1371/journal.ppat.1011591
PMCID:
PMC10461841
AbstractArticlePDF–2.6M
4.
Hepcidin deficiency in mice impairs white adipose tissue browning possibly due to a defect in de novo adipogenesis
Jean-Christophe Deschemin, Céline Ransy, Frédéric Bouillaud, Soonkyu Chung, Bruno Galy, Carole Peyssonnaux, Sophie Vaulont
Sci Rep. 2023; 13: 12794. Published online 2023 Aug 7. doi: 10.1038/s41598-023-39305-0
PMCID:
PMC10406828
AbstractArticlePDF–7.0M
5.
Oxidative stress induces lysosomal membrane permeabilization and ceramide accumulation in retinal pigment epithelial cells
Kevin R. Zhang, Connor S. R. Jankowski, Rayna Marshall, Rohini Nair, Néstor Más Gómez, Ahab Alnemri, Yingrui Liu, Elizabeth Erler, Julia Ferrante, Ying Song, Brent A. Bell, Bailey H. Baumann, Jacob Sterling, Brandon Anderson, Sierra Foshe, Jennifer Roof, Hossein Fazelinia, Lynn A. Spruce, Jen-Zen Chuang, Ching-Hwa Sung, Anuradha Dhingra, Kathleen Boesze-Battaglia, Venkata R. M. Chavali, Joshua D. Rabinowitz, Claire H. Mitchell, Joshua L. Dunaief
Dis Model Mech. 2023 Jul 1; 16(7): dmm050066. Published online 2023 Jul 25. doi: 10.1242/dmm.050066
PMCID:
PMC10399446
AbstractArticle
6.
Bone-derived C-terminal FGF23 cleaved peptides increase iron availability in acute inflammation
Guillaume Courbon, Jane Joy Thomas, Marta Martinez-Calle, Xueyan Wang, Jadeah Spindler, John Von Drasek, Bridget Hunt-Tobey, Rupal Mehta, Tamara Isakova, Wenhan Chang, John W. M. Creemers, Peng Ji, Aline Martin, Valentin David
Blood. 2023 Jul 6; 142(1): 106–118. Published online 2023 Apr 16. doi: 10.1182/blood.2022018475
PMCID:
PMC10356820
AbstractArticle
7.
Low ceruloplasmin levels exacerbate retinal degeneration in a hereditary hemochromatosis model
Brandon D. Anderson, Timothy Lee, Brent Bell, Ying Song, Joshua L. Dunaief
Dis Model Mech. 2023 Jul 1; 16(7): dmm050226. Published online 2023 Jul 13. doi: 10.1242/dmm.050226
PMCID:
PMC10354715
AbstractArticle
8.
Genetic Iron Overload Hampers Development of Cutaneous Leishmaniasis in Mice
Edouard Charlebois, Yupeng Li, Victoria Wagner, Kostas Pantopoulos, Martin Olivier
Int J Mol Sci. 2023 Jan; 24(2): 1669. Published online 2023 Jan 14. doi: 10.3390/ijms24021669
PMCID:
PMC9864902
AbstractArticlePDF–3.3M
9.
A mouse model of anemia of inflammation: complex pathogenesis with partial dependence on hepcidin
Airie Kim, Eileen Fung, Sona G. Parikh, Erika V. Valore, Victoria Gabayan, Elizabeta Nemeth, Tomas Ganz
Blood. 2014 Feb 20; 123(8): 1129–1136. Prepublished online 2013 Dec 19. doi: 10.1182/blood-2013-08-521419
PMCID:
PMC9632791
AbstractArticle
10.
In iron-deficient mouse pregnancies, erythroferrone contributes to iron mobilization for embryo erythropoiesis
Veena Sangkhae, Vivian Yu, Richard Coffey, Kimberly O. O’Brien, Tomas Ganz, Elizabeta Nemeth
Am J Hematol. Author manuscript; available in PMC 2023 Oct 1.
Published in final edited form as: Am J Hematol. 2022 Oct; 97(10): 1348–1358. Published online 2022 Aug 16. doi: 10.1002/ajh.26680
PMCID:
PMC9462668
AbstractArticlePDF–1.9M
11.
Astrocyte-derived hepcidin controls iron traffic at the blood-brain-barrier via regulating ferroportin 1 of microvascular endothelial cells
Linhao You, Pan-Pan Yu, Tianyu Dong, Wenhuan Guo, Shiyang Chang, Bingjie Zheng, Yunzhe Ci, Fudi Wang, Peng Yu, Guofen Gao, Yan-Zhong Chang
Cell Death Dis. 2022 Aug; 13(8): 667. Published online 2022 Aug 1. doi: 10.1038/s41419-022-05043-w
PMCID:
PMC9343463
AbstractArticlePDF–5.5M
12.
Investigating the Molecular Mechanisms of Renal Hepcidin Induction and Protection upon Hemoglobin-Induced Acute Kidney Injury
Laura E. Diepeveen, Gaby Stegemann, Erwin T. Wiegerinck, Rian Roelofs, Myrthe Naber, Olivier Lóreal, Bart Smeets, Frank Thévenod, Dorine W. Swinkels, Rachel P. L. van Swelm
Int J Mol Sci. 2022 Feb; 23(3): 1352. Published online 2022 Jan 25. doi: 10.3390/ijms23031352
PMCID:
PMC8835743
AbstractArticlePDF–2.2M
13.
Aging is associated with increased brain iron through cortex-derived hepcidin expression
Tatsuya Sato, Jason Solomon Shapiro, Hsiang-Chun Chang, Richard A Miller, Hossein Ardehali
eLife. 2022; 11: e73456. Published online 2022 Jan 11. doi: 10.7554/eLife.73456
PMCID:
PMC8752087
AbstractArticlePDF–926K
14.
Hepatocyte neogenin is required for hemojuvelin-mediated hepcidin expression and iron homeostasis in mice
Caroline A. Enns, Shall Jue, An-Sheng Zhang
Blood. 2021 Aug 12; 138(6): 486–499. Prepublished online 2021 Apr 6. doi: 10.1182/blood.2020009485
PMCID:
PMC8370464
AbstractArticle
15.
Involvement of Hepcidin in Cognitive Damage Induced by Chronic Intermittent Hypoxia in Mice
Ya-Shuo Zhao, Miao Tan, Ji-Xian Song, Ji-Ren An, Xin-Yue Yang, Wen-Ya Li, Ya-Jing Guo, En-Sheng Ji
Oxid Med Cell Longev. 2021; 2021: 8520967. Published online 2021 Aug 4. doi: 10.1155/2021/8520967
PMCID:
PMC8357469
AbstractArticlePDF–3.9M
16.
Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy
Allison L. Fisher, Veena Sangkhae, Kamila Balušíková, Nicolaos J. Palaskas, Tomas Ganz, Elizabeta Nemeth
Nat Commun. 2021; 12: 4026. Published online 2021 Jun 29. doi: 10.1038/s41467-021-24333-z
PMCID:
PMC8242011
AbstractArticlePDF–5.4M
17.
Oral Administration of Ginger-Derived Lipid Nanoparticles and Dmt1 siRNA Potentiates the Effect of Dietary Iron Restriction and Mitigates Pre-Existing Iron Overload in Hamp KO Mice
Xiaoyu Wang, Mingzhen Zhang, Regina R. Woloshun, Yang Yu, Jennifer K. Lee, Shireen R. L. Flores, Didier Merlin, James F. Collins
Nutrients. 2021 May; 13(5): 1686. Published online 2021 May 15. doi: 10.3390/nu13051686
PMCID:
PMC8157040
AbstractArticlePDF–2.3M
18.
Hepcidin-induced reduction in iron content and PGC-1β expression negatively regulates osteoclast differentiation to play a protective role in postmenopausal osteoporosis
Hui Zhang, Aifei Wang, Guangsi Shen, Xiao Wang, Gongwen Liu, Fan Yang, Bin Chen, Mingyong Wang, Youjia Xu
Aging (Albany NY) 2021 Apr 30; 13(8): 11296–11314. Published online 2021 Apr 4. doi: 10.18632/aging.202817
PMCID:
PMC8109081
AbstractArticlePDF–2.2M
19.
Salmonella effector SpvB aggravates dysregulation of systemic iron metabolism via modulating the hepcidin−ferroportin axis
Qifeng Deng, Sidi Yang, Lanqing Sun, Kedi Dong, Yuanyuan Li, Shuyan Wu, Rui Huang
Gut Microbes. 2021; 13(1): 1849996. Published online 2021 Jan 21. doi: 10.1080/19490976.2020.1849996
PMCID:
PMC7833757
AbstractArticlePDF–4.1M
20.
Hepcidin is essential for alveolar macrophage function and is disrupted by smoke in a murine COPD model
Elizabeth Perez, Jonathan R. Baker, Silvana Di Giandomenico, Pouneh Kermani, Jacqueline Parker, Kihwan Kim, Jianjun Yang, Peter J. Barnes, Sophie Vaulont, Joseph M. Scandura, Louise E. Donnelly, Heather Stout-Delgado, Suzanne M. Cloonan
J Immunol. Author manuscript; available in PMC 2021 Nov 1.
Published in final edited form as: J Immunol. 2020 Nov 1; 205(9): 2489–2498. Published online 2020 Sep 21. doi: 10.4049/jimmunol.1901284
PMCID:
PMC7805484
AbstractArticlePDF–1.3M

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