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Items: 1 to 20 of 128

1.
Dual therapeutic targeting of MYC and JUNB transcriptional programs for enhanced anti-myeloma activity
Judith Lind, Osman Aksoy, Michaela Prchal-Murphy, Fengjuan Fan, Mariateresa Fulciniti, Dagmar Stoiber, Latifa Bakiri, Erwin F. Wagner, Elisabeth Zwickl-Traxler, Martin Sattler, Karoline Kollmann, Sonia Vallet, Klaus Podar
Blood Cancer J. 2024 Dec; 14(1): 138. Published online 2024 Aug 19. doi: 10.1038/s41408-024-01117-4
PMCID:
PMC11333473
AbstractArticlePDF–3.4M
2.
A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex
Marisa Bedir, Emily Outwin, Rita Colnaghi, Lydia Bassett, Iga Abramowicz, Mark O’Driscoll
EMBO Rep. 2024 Aug; 25(8): 3432–3455. Published online 2024 Jun 28. doi: 10.1038/s44319-024-00184-9
PMCID:
PMC11315929
AbstractArticlePDF–3.4M
3.
Comprehensive Analysis of CXCR4, JUNB, and PD-L1 Expression in Circulating Tumor Cells (CTCs) from Prostate Cancer Patients
Argyro Roumeliotou, Areti Strati, Foteini Chamchougia, Anastasia Xagara, Victoria Tserpeli, Stavroula Smilkou, Elina Lagopodi, Athina Christopoulou, Emmanouil Kontopodis, Ioannis Drositis, Nikolaos Androulakis, Vassilis Georgoulias, Filippos Koinis, Athanasios Kotsakis, Evi Lianidou, Galatea Kallergi
Cells. 2024 May; 13(9): 782. Published online 2024 May 3. doi: 10.3390/cells13090782
PMCID:
PMC11083423
AbstractArticlePDF–2.5M
4.
JunB condensation attenuates vascular endothelial damage under hyperglycemic condition
Xuxia Ren, Zexu Cui, Qiaoqiao Zhang, Zhiguang Su, Wei Xu, Jinhui Wu, Hao Jiang
J Mol Cell Biol. 2023 Dec; 15(12): mjad072. Published online 2023 Dec 22. doi: 10.1093/jmcb/mjad072
PMCID:
PMC11080659
AbstractArticlePDF–2.3M
5.
Spatiotemporal Transcriptome Analysis Reveals Activation of the AP1 Pathway in the Ovarian Microenvironment during the Transition from Premenopause to Postmenopause
Wendi Pei, Xiaomin Cao, Puyao Zhang, Lin Fu, Ping Zhou, Ye Liu, Yong Fan, Fengqin Xu, Canhui Cao, Yang Yu
Aging Dis. 2024 Apr 1; 15(2): 445–448. Published online 2024 Apr 1. doi: 10.14336/AD.2023.0707-1
PMCID:
PMC10917534
ArticlePDF–599K
6.
AP-1 signaling modulates cardiac fibroblast stress responses
Alexander J. Whitehead, Hamza Atcha, James D. Hocker, Bing Ren, Adam J. Engler
J Cell Sci. 2023 Dec 1; 136(23): jcs261152. Published online 2023 Dec 15. doi: 10.1242/jcs.261152
PMCID:
PMC10753496
AbstractArticle
7.
Transcription Factor JunB Suppresses Hepatitis C Virus Replication
ADI ARIFFIANTO, LIN DENG, SAKI HARADA, YUJIAO LIANG, CHIEKO MATSUI, TAKAYUKI ABE, IKUO SHOJI
Kobe J Med Sci. 2023; 69(3): E86–E95. Published online 2023 Aug 31.
PMCID:
PMC10695097
AbstractArticlePDF–641K
8.
JUNB mediates oxaliplatin resistance via the MAPK signaling pathway in gastric cancer by chromatin accessibility and transcriptomic analysis: JUNB mediates oxaliplatin resistance in gastric cancer
Suyao Li, Yichou Wei, Xun Sun, Mengling Liu, Mengxuan Zhu, Yitao Yuan, Jiayu Zhang, Yu Dong, Keshu Hu, Sining Ma, Xiuping Zhang, Bei Xu, Hesheng Jiang, Lu Gan, Tianshu Liu
Acta Biochim Biophys Sin (Shanghai) 2023 Nov 25; 55(11): 1784–1796. Published online 2023 Jun 19. doi: 10.3724/abbs.2023119
PMCID:
PMC10679881
AbstractArticlePDF–3.2M
9.
Shock drives a STAT3 and JunB-mediated coordinated transcriptional and DNA methylation response in the endothelium
Ramon Bossardi Ramos, Nina Martino, Dareen Chuy, Shuhan Lu, Mei Xing G. Zuo, Uma Balasubramanian, Iria Di John Portela, Peter A. Vincent, Alejandro P. Adam
J Cell Sci. 2023 Sep 15; 136(18): jcs261323. Published online 2023 Sep 25. doi: 10.1242/jcs.261323
PMCID:
PMC10560554
AbstractArticle
10.
ZIC2 induces pro-tumor macrophage polarization in nasopharyngeal carcinoma by activating the JUNB/MCSF axis
Qian Liu, Ting Yang, Yu Zhang, Ze-Dong Hu, Yan-Min Liu, Yi-Ling Luo, Shang-Xin Liu, Hua Zhang, Qian Zhong
Cell Death Dis. 2023 Jul; 14(7): 455. Published online 2023 Jul 21. doi: 10.1038/s41419-023-05983-x
PMCID:
PMC10362010
AbstractArticlePDF–6.1M
11.
AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor
Philipp Trepte, Christopher Secker, Simona Kostova, Sibusiso B. Maseko, Soon Gang Choi, Jeremy Blavier, Igor Minia, Eduardo Silva Ramos, Patricia Cassonnet, Sabrina Golusik, Martina Zenkner, Stephanie Beetz, Mara J. Liebich, Nadine Scharek, Anja Schütz, Marcel Sperling, Michael Lisurek, Yang Wang, Kerstin Spirohn, Tong Hao, Michael A. Calderwood, David E. Hill, Markus Landthaler, Julien Olivet, Jean-Claude Twizere, Marc Vidal, Erich E. Wanker
Version 1. bioRxiv. Preprint. 2023 Jun 14. doi: 10.1101/2023.06.14.544560
Published in:
Mol Syst Biol. 2024 Apr; 20(4): 428–457.
PMCID:
PMC10312674
AbstractArticlePDF–9.6M
12.
AP-1 subunit JUNB promotes invasive phenotypes in endometriosis
Mike R. Wilson, Jake J. Reske, Ronald L. Chandler
Reprod Sci. Author manuscript; available in PMC 2023 Nov 1.
Published in final edited form as: Reprod Sci. 2022 Nov; 29(11): 3266–3277. Published online 2022 May 26. doi: 10.1007/s43032-022-00974-3
PMCID:
PMC9669088
AbstractArticlePDF–1.6M
13.
m6A RNA methylation regulates the transcription factors JUN and JUNB in TGF-β-induced epithelial–mesenchymal transition of lung cancer cells
Kusuma Suphakhong, Minoru Terashima, Sasithorn Wanna-udom, Risa Takatsuka, Akihiko Ishimura, Takahisa Takino, Takeshi Suzuki
J Biol Chem. 2022 Nov; 298(11): 102554. Published online 2022 Sep 29. doi: 10.1016/j.jbc.2022.102554
PMCID:
PMC9619186
AbstractArticlePDF–2.1M
14.
FGF7/FGFR2–JunB signalling counteracts the effect of progesterone in luminal breast cancer
Kamil Mieczkowski, Kamila Kitowska, Marcin Braun, Barbara Galikowska‐Bogut, Monika Gorska‐Arcisz, Dominika Piasecka, Konrad Stawiski, Anna J. Zaczek, Dariusz Nejc, Radzisław Kordek, Hanna M. Romanska, Rafal Sadej
Mol Oncol. 2022 Aug; 16(15): 2823–2842. Published online 2022 Jul 4. doi: 10.1002/1878-0261.13274
PMCID:
PMC9348598
AbstractArticlePDF–3.6M
15.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
16.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
17.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
18.
CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity
Julia Joung, Paul C. Kirchgatterer, Ankita Singh, Jang H. Cho, Suchita P. Nety, Rebecca C. Larson, Rhiannon K. Macrae, Rebecca Deasy, Yuen-Yi Tseng, Marcela V. Maus, Feng Zhang
Nat Commun. 2022; 13: 1606. Published online 2022 Mar 25. doi: 10.1038/s41467-022-29205-8
PMCID:
PMC8956604
AbstractArticlePDF–3.9M
19.
Restriction factor screening identifies RABGAP1L-mediated disruption of endocytosis as a host antiviral defense
Sonja Fernbach, Eva E. Spieler, Idoia Busnadiego, Umut Karakus, Anouk Lkharrazi, Silke Stertz, Benjamin G. Hale
Cell Rep. 2022 Mar 22; 38(12): 110549. Published online 2022 Mar 22. doi: 10.1016/j.celrep.2022.110549
PMCID:
PMC8939003
AbstractArticlePDF–5.6M
20.
Human transcription factor protein interaction networks
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5
PMCID:
PMC8828895
AbstractArticlePDF–1.7M

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