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Select item 111899741.

Mutant TP53 promotes invasion of lung cancer cells by regulating desmoglein 3

Yu Feng, Rulin Qian, Dong Cui, Jiaqiang Luan, Mingxing Xu, Ling Wang, Ruijie Li, Xiao Wu, Chaoying Chang

J Cancer Res Clin Oncol. 2024; 150(6): 312. Published online 2024 Jun 20. doi: 10.1007/s00432-024-05778-3

PMCID:: PMC11189974

Abstract Article PDF–3.6M

Select item 111138442.

E-cadherin and Src associate with extradesmosomal Dsg3 and modulate desmosome assembly and adhesion

Vera Rötzer, Eva Hartlieb, Franziska Vielmuth, Martin Gliem, Volker Spindler, Jens Waschke

Cell Mol Life Sci. 2015 Dec; 72(24): 4885–4897. Published online 2015 Jun 27. doi: 10.1007/s00018-015-1977-0

PMCID:: PMC11113844

Abstract Article PDF–2.4M

Select item 99504473.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 98162594.

Cytoskeletal anchorage of different Dsg3 pools revealed by combination of hybrid STED/SMFS-AFM

Michael Fuchs, Mariya Y. Radeva, Volker Spindler, Franziska Vielmuth, Daniela Kugelmann, Jens Waschke

Cell Mol Life Sci. 2023 Jan; 80(1): 25. Published online 2023 Jan 5. doi: 10.1007/s00018-022-04681-9

PMCID:: PMC9816259

Abstract Article PDF–16M

Select item 91960365.

Dsg1 and Dsg3 Composition of Desmosomes Across Human Epidermis and Alterations in Pemphigus Vulgaris Patient Skin

Thomas Schmitt, Julia Pircher, Letyfee Steinert, Katharina Meier, Kamran Ghoreschi, Franziska Vielmuth, Daniela Kugelmann, Jens Waschke

Front Immunol. 2022; 13: 884241. Published online 2022 May 25. doi: 10.3389/fimmu.2022.884241

PMCID:: PMC9196036

Abstract Article PDF–14M

Select item 90199006.

Desmoglein‐3 induces YAP phosphorylation and inactivation during collective migration of oral carcinoma cells

Usama Sharif Ahmad, Eric Kenneth Parkinson, Hong Wan

Mol Oncol. 2022 Apr; 16(8): 1625–1649. Published online 2022 Mar 1. doi: 10.1002/1878-0261.13177

PMCID:: PMC9019900

Abstract Article PDF–11M

Select item 89939207.

Up-regulation of ST18 in pemphigus vulgaris drives a self-amplifying p53-dependent pathomechanism resulting in decreased desmoglein 3 expression

Sari Assaf, Dan Vodo, Kiril Malovitski, Janan Mohamad, Shir Bergson, Yarden Feller, Liron Malki, Ofer Sarig, Eli Sprecher

Sci Rep. 2022; 12: 5958. Published online 2022 Apr 8. doi: 10.1038/s41598-022-09951-x

PMCID:: PMC8993920

Abstract Article PDF–2.3M

Select item 85664738.

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma

Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim

Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6

PMCID:: PMC8566473

Abstract Article PDF–2.7M

Select item 81650309.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 772155710.

Correlation of Tumor Marker Expression with Nodal Disease Burden in Metastatic Head and Neck Cancer

Sumita Trivedi, Jose Mattos, William Gooding, Tony E. Godfrey, Robert L. Ferris

Otolaryngol Head Neck Surg. Author manuscript; available in PMC 2020 Dec 7.

Published in final edited form as: Otolaryngol Head Neck Surg. 2013 Aug; 149(2): 261–268. Published online 2013 Apr 26. doi: 10.1177/0194599813486876

PMCID:: PMC7721557

Abstract Article PDF–515K

Select item 695724911.

Protein kinase C isoenzymes differentially regulate the differentiation-dependent expression of adhesion molecules in human epidermal keratinocytes

Andrea Szegedi, Edit Páyer, Gabriella Czifra, Balázs I. Tóth, Emese Schmidt, László Kovács, Peter M. Blumberg, Tamás Bíró

Exp Dermatol. Author manuscript; available in PMC 2020 Jan 13.

Published in final edited form as: Exp Dermatol. 2009 Feb; 18(2): 122–129. Published online 2008 Jul 7. doi: 10.1111/j.1600-0625.2008.00771.x

PMCID:: PMC6957249

Abstract Article PDF–754K

Select item 694093612.

Evidence for the Desmosomal Cadherin Desmoglein-3 in Regulating YAP and Phospho-YAP in Keratinocyte Responses to Mechanical Forces

Jutamas Uttagomol, Usama Sharif Ahmad, Ambreen Rehman, Yunying Huang, Ana C. Laly, Angray Kang, Jan Soetaert, Randy Chance, Muy-Teck Teh, John T. Connelly, Hong Wan

Int J Mol Sci. 2019 Dec; 20(24): 6221. Published online 2019 Dec 10. doi: 10.3390/ijms20246221

PMCID:: PMC6940936

Abstract Article PDF–12M

Select item 677655113.

The desmosomal cadherin desmoglein-3 acts as a keratinocyte anti-stress protein via suppression of p53

Ambreen Rehman, Yang Cai, Christian Hünefeld, Hana Jedličková, Yunying Huang, Muy Teck Teh, Usama Sharif Ahmad, Jutamas Uttagomol, Ying Wang, Angray Kang, Gary Warnes, Catherine Harwood, Daniele Bergamaschi, Eric Kenneth Parkinson, Martin Röcken, Hong Wan

Cell Death Dis. 2019 Oct; 10(10): 750. Published online 2019 Oct 3. doi: 10.1038/s41419-019-1988-0

PMCID:: PMC6776551

Abstract Article PDF–6.1M

Select item 649616314.

RNAi‐mediated inhibition of the desmosomal cadherin (desmoglein 3) impairs epithelial cell proliferation

T. Mannan, S. Jing, S. H. Foroushania, F. Fortune, H. Wan

Cell Prolif. 2011 Aug; 44(4): 301–310. Published online 2011 Jun 27. doi: 10.1111/j.1365-2184.2011.00765.x

PMCID:: PMC6496163

Abstract Article PDF–832K

Select item 599693415.

Keratin Retraction and Desmoglein3 Internalization Independently Contribute to Autoantibody-Induced Cell Dissociation in Pemphigus Vulgaris

Elisabeth Schlögl, Mariya Y. Radeva, Franziska Vielmuth, Camilla Schinner, Jens Waschke, Volker Spindler

Front Immunol. 2018; 9: 858. Published online 2018 Apr 25. doi: 10.3389/fimmu.2018.00858

PMCID:: PMC5996934

Abstract Article PDF–15M

Select item 576848816.

Desmoglein 3 Order and Dynamics in Desmosomes Determined by Fluorescence Polarization Microscopy

Emily I. Bartle, Tara M. Urner, Siddharth S. Raju, Alexa L. Mattheyses

Biophys J. 2017 Dec 5; 113(11): 2519–2529. Published online 2017 Dec 5. doi: 10.1016/j.bpj.2017.09.028

PMCID:: PMC5768488

Abstract Article PDF–3.5M

Select item 553161117.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 547945518.

Desmoglein 3 regulates membrane trafficking of cadherins, an implication in cell-cell adhesion

Hanan Moftah, Kasuni Dias, Ehsanul Hoque Apu, Li Liu, Jutamas Uttagomol, Lesley Bergmeier, Stephanie Kermorgant, Hong Wan

Cell Adh Migr. 2017; 11(3): 211–232. Published online 2016 Jun 2. doi: 10.1080/19336918.2016.1195942

PMCID:: PMC5479455

Abstract Article PDF–1.8M

Select item 547259319.

Different signaling patterns contribute to loss of keratinocyte cohesion dependent on autoantibody profile in pemphigus

Elias Walter, Franziska Vielmuth, Lukas Rotkopf, Miklós Sárdy, Orsolya N. Horváth, Matthias Goebeler, Enno Schmidt, Rüdiger Eming, Michael Hertl, Volker Spindler, Jens Waschke

Sci Rep. 2017; 7: 3579. Published online 2017 Jun 15. doi: 10.1038/s41598-017-03697-7

PMCID:: PMC5472593

Abstract Article PDF–5.7M

Select item 492201620.

Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes

Frauke Völlner, Jawahir Ali, Nina Kurrle, Yvonne Exner, Rüdiger Eming, Michael Hertl, Antje Banning, Ritva Tikkanen

Sci Rep. 2016; 6: 28820. Published online 2016 Jun 27. doi: 10.1038/srep28820

PMCID:: PMC4922016

Abstract Article PDF–2.1M

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