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Items: 1 to 20 of 51

1.
Large‐scale phosphomimetic screening identifies phospho‐modulated motif‐based protein interactions
Johanna Kliche, Dimitriya Hristoforova Garvanska, Leandro Simonetti, Dilip Badgujar, Doreen Dobritzsch, Jakob Nilsson, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2023 Jul; 19(7): e11164. Published online 2023 May 23. doi: 10.15252/msb.202211164
PMCID:
PMC10333884
AbstractArticlePDF–5.0M
2.
ATG5 selectively engages virus-tethered BST2/tetherin in an LC3C-associated pathway
Delphine Judith, Margaux Versapuech, Fabienne Bejjani, Marjory Palaric, Pauline Verlhac, Aurelia Kuster, Leslie Lepont, Sarah Gallois-Montbrun, Katy Janvier, Clarisse Berlioz-Torrent
Proc Natl Acad Sci U S A. 2023 May 16; 120(20): e2217451120. Published online 2023 May 8. doi: 10.1073/pnas.2217451120
PMCID:
PMC10193943
AbstractArticlePDF–3.7M
3.
Microtubule-associated protein MAP1LC3C regulates lysosomal exocytosis and induces zinc reprogramming in renal cancer cells
Rita Verma, Parul Aggarwal, Megan E. Bischoff, James Reigle, Dina Secic, Collin Wetzel, Katherine VandenHeuvel, Jacek Biesiada, Birgit Ehmer, Julio A. Landero Figueroa, David R. Plas, Mario Medvedovic, Jarek Meller, Maria F. Czyzyk-Krzeska
J Biol Chem. 2023 May; 299(5): 104663. Published online 2023 Mar 30. doi: 10.1016/j.jbc.2023.104663
PMCID:
PMC10173779
AbstractArticlePDF–5.6M
4.
TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1
Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel
J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144
PMCID:
PMC9797988
AbstractArticlePDF–6.9M
5.
An ALS-associated variant of the autophagy receptor SQSTM1/p62 reprograms binding selectivity toward the autophagy-related hATG8 proteins
Andrew Brennan, Robert Layfield, Jed Long, Huw E.L. Williams, Neil J. Oldham, Daniel Scott, Mark S. Searle
J Biol Chem. 2022 Feb; 298(2): 101514. Published online 2021 Dec 18. doi: 10.1016/j.jbc.2021.101514
PMCID:
PMC8762078
AbstractArticlePDF–2.4M
6.
The BAX-binding protein MOAP1 associates with LC3 and promotes closure of the phagophore
Hao-Chun Chang, Ran N. Tao, Chong Teik Tan, Ya Jun Wu, Boon Huat Bay, Victor C. Yu
Autophagy. 2021; 17(11): 3725–3739. Published online 2021 Mar 30. doi: 10.1080/15548627.2021.1896157
PMCID:
PMC8632279
AbstractArticlePDF–7.5M
7.
Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities
Thomas Kruse, Caroline Benz, Dimitriya H. Garvanska, Richard Lindqvist, Filip Mihalic, Fabian Coscia, Raviteja Inturi, Ahmed Sayadi, Leandro Simonetti, Emma Nilsson, Muhammad Ali, Johanna Kliche, Ainhoa Moliner Morro, Andreas Mund, Eva Andersson, Gerald McInerney, Matthias Mann, Per Jemth, Norman E. Davey, Anna K. Överby, Jakob Nilsson, Ylva Ivarsson
Nat Commun. 2021; 12: 6761. Published online 2021 Nov 19. doi: 10.1038/s41467-021-26498-z
PMCID:
PMC8605023
AbstractArticlePDF–8.0M
8.
Characterization of a natural variant of human NDP52 and its functional consequences on mitophagy
Anthea Di Rita, Daniela F. Angelini, Teresa Maiorino, Valerio Caputo, Raffaella Cascella, Mukesh Kumar, Matteo Tiberti, Matteo Lambrughi, Nicole Wesch, Frank Löhr, Volker Dötsch, Marianna Carinci, Pasquale D’Acunzo, Valerio Chiurchiù, Elena Papaleo, Vladimir V. Rogov, Emiliano Giardina, Luca Battistini, Flavie Strappazzon
Cell Death Differ. 2021 Aug; 28(8): 2499–2516. Published online 2021 Mar 15. doi: 10.1038/s41418-021-00766-3
PMCID:
PMC8329179
AbstractArticlePDF–3.8M
9.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
10.
SAMM50 acts with p62 in piecemeal basal- and OXPHOS-induced mitophagy of SAM and MICOS components
Yakubu Princely Abudu, Birendra Kumar Shrestha, Wenxin Zhang, Anthimi Palara, Hanne Britt Brenne, Kenneth Bowitz Larsen, Deanna Lynn Wolfson, Gianina Dumitriu, Cristina Ionica Øie, Balpreet Singh Ahluwalia, Gahl Levy, Christian Behrends, Sharon A. Tooze, Stephane Mouilleron, Trond Lamark, Terje Johansen
J Cell Biol. 2021 Aug 2; 220(8): e202009092. Published online 2021 May 26. doi: 10.1083/jcb.202009092
PMCID:
PMC8160579
AbstractArticlePDF–10M
11.
Selective MAP1LC3C (LC3C) autophagy requires noncanonical regulators and the C-terminal peptide
Megan E. Bischoff, Yuanwei Zang, Johnson Chu, Adam D. Price, Birgit Ehmer, Nicholas J. Talbot, Michael J. Newbold, Anurag Paul, Jun-Lin Guan, David R. Plas, Jarek Meller, Maria F. Czyzyk-Krzeska
J Cell Biol. 2021 Jul 5; 220(7): e202004182. Published online 2021 May 14. doi: 10.1083/jcb.202004182
PMCID:
PMC8129795
AbstractArticlePDF–9.9M
12.
TFG binds LC3C to regulate ULK1 localization and autophagosome formation
Marianna Carinci, Beatrice Testa, Matteo Bordi, Giacomo Milletti, Massimo Bonora, Laura Antonucci, Caterina Ferraina, Marta Carro, Mukesh Kumar, Donatella Ceglie, Franziska Eck, Roberta Nardacci, Francois le Guerroué, Stefania Petrini, Maria E Soriano, Ignazio Caruana, Valentina Doria, Maria Manifava, Camille Peron, Matteo Lambrughi, Valeria Tiranti, Christian Behrends, Elena Papaleo, Paolo Pinton, Carlotta Giorgi, Nicholas T Ktistakis, Franco Locatelli, Francesca Nazio, Francesco Cecconi
EMBO J. 2021 May 17; 40(10): e103563. Published online 2021 May 1. doi: 10.15252/embj.2019103563
PMCID:
PMC8126910
AbstractArticlePDF–2.4M
13.
Autophagy-Related Protein MAP1LC3C Plays a Crucial Role in Odontogenic Differentiation of Human Dental Pulp Cells
Heui Seung Cho, Sam Young Park, Sun Mi Kim, Won Jae Kim, Ji Yeon Jung
Tissue Eng Regen Med. 2021 Apr; 18(2): 265–277. Published online 2020 Nov 24. doi: 10.1007/s13770-020-00310-3
PMCID:
PMC8012421
AbstractArticlePDF–2.7M
14.
Cytoplasmic short linear motifs in ACE2 and integrin β3 link SARS-CoV-2 host cell receptors to mediators of endocytosis and autophagy
Johanna Kliche, Hanna Kuss, Muhammad Ali, Ylva Ivarsson
Sci Signal. 2021 Jan 12; 14(665): eabf1117. doi: 10.1126/scisignal.abf1117
PMCID:
PMC7928716
AbstractArticlePDF–1017K
15.
Mass spectrometry proteomics reveals a function for mammalian CALCOCO1 in MTOR-regulated selective autophagy
Jonathan A. Stefely, Yu Zhang, Elyse C. Freiberger, Nicholas W. Kwiecien, Hala Elnakat Thomas, Alexander M. Davis, Nathaniel D. Lowry, Catherine E. Vincent, Evgenia Shishkova, Nicholas A. Clark, Mario Medvedovic, Joshua J. Coon, David J. Pagliarini, Carol A. Mercer
Autophagy. 2020; 16(12): 2219–2237. Published online 2020 Feb 2. doi: 10.1080/15548627.2020.1719746
PMCID:
PMC7751563
AbstractArticlePDF–6.2M
16.
Novel Insights into the Cellular Localization and Regulation of the Autophagosomal Proteins LC3A, LC3B and LC3C
Marius W. Baeken, Katja Weckmann, Philip Diefenthäler, Jan Schulte, Kamran Yusifli, Bernd Moosmann, Christian Behl, Parvana Hajieva
Cells. 2020 Oct; 9(10): 2315. Published online 2020 Oct 18. doi: 10.3390/cells9102315
PMCID:
PMC7603224
AbstractArticlePDF–15M
17.
TECPR1 promotes aggrephagy by direct recruitment of LC3C autophagosomes to lysosomes
Lisa Wetzel, Stéphane Blanchard, Sowmya Rama, Viola Beier, Anna Kaufmann, Thomas Wollert
Nat Commun. 2020; 11: 2993. Published online 2020 Jun 12. doi: 10.1038/s41467-020-16689-5
PMCID:
PMC7293217
AbstractArticlePDF–9.5M
18.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
19.
Disrupting the TRIB3-SQSTM1 interaction reduces liver fibrosis by restoring autophagy and suppressing exosome-mediated HSC activation
Xiao-Wei Zhang, Ji-Chao Zhou, Dian Peng, Fang Hua, Ke Li, Jiao-Jiao Yu, Xiao-Xi Lv, Bing Cui, Shan-Shan Liu, Jin-Mei Yu, Feng Wang, Cai-Cai Jin, Zhao-Na Yang, Chen-Xi Zhao, Xue-Ying Hou, Bo Huang, Zhuo-Wei Hu
Autophagy. 2020; 16(5): 782–796. Published online 2019 Jul 9. doi: 10.1080/15548627.2019.1635383
PMCID:
PMC7144866
AbstractArticlePDF–6.5M
20.
LC3C mediates selective autophagy of the MET RTK, inhibiting cancer cell invasion
Emily S. Bell, Paula Pinto Coelho, Morag Park
Autophagy. 2020; 16(5): 959–961. Published online 2020 Feb 16. doi: 10.1080/15548627.2020.1728099
PMCID:
PMC7144864
AbstractArticlePDF–1019K

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