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Items: 1 to 20 of 62

1.
STK40 inhibits trophoblast fusion by mediating COP1 ubiquitination to degrade P57Kip2
Xia Li, Li-Zhen Shao, Zhuo-Hang Li, Yong-Heng Wang, Qin-Yu Cai, Shun Wang, Hong Chen, Jie Sheng, Xin Luo, Xue-Mei Chen, Ying-Xiong Wang, Yu-Bin Ding, Tai-Hang Liu
J Transl Med. 2024; 22: 852. Published online 2024 Sep 20. doi: 10.1186/s12967-024-05360-y
PMCID:
PMC11414097
AbstractArticlePDF–8.5M
2.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
3.
Effect of COP1 in Promoting the Tumorigenesis of Gastric Cancer by Down-Regulation of CDH18 via PI3K/AKT Signal Pathway
Benhuo Zhao, Jiaojiao Wu, Xiuli Cha, Guangtong Mao, Hengliang Shi, Sujuan Fei, Bei Miao
Anal Cell Pathol (Amst) 2023; 2023: 5617875. Published online 2023 Mar 28. doi: 10.1155/2023/5617875
PMCID:
PMC10072965
AbstractArticlePDF–6.6M
4.
Structural basis of bacterial effector protein azurin targeting tumor suppressor p53 and inhibiting its ubiquitination
Jianjian Hu, Wenxue Jiang, Jiaqi Zuo, Dujuan Shi, Xiaoqi Chen, Xiao Yang, Wenhui Zhang, Lixin Ma, Zhu Liu, Qiong Xing
Commun Biol. 2023; 6: 59. Published online 2023 Jan 17. doi: 10.1038/s42003-023-04458-1
PMCID:
PMC9845241
AbstractArticlePDF–3.3M
5.
A COP1-GATA2 axis suppresses AR signaling and prostate cancer
Tao Shen, Bingning Dong, Yanling Meng, David D. Moore, Feng Yang
Proc Natl Acad Sci U S A. 2022 Oct 25; 119(43): e2205350119. Published online 2022 Oct 17. doi: 10.1073/pnas.2205350119
PMCID:
PMC9618149
AbstractArticlePDF–2.2M
6.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
7.
Transcription Factor Protein Interactomes Reveal Genetic Determinants in Heart Disease
Barbara Gonzalez-Teran, Maureen Pittman, Franco Felix, Reuben Thomas, Desmond Richmond-Buccola, Ruth Hüttenhain, Krishna Choudhary, Elisabetta Moroni, Mauro W. Costa, Yu Huang, Arun Padmanabhan, Michael Alexanian, Clara Youngna Lee, Bonnie E. J. Maven, Kaitlen Samse-Knapp, Sarah U. Morton, Michael McGregor, Casey A. Gifford, J. G. Seidman, Christine E. Seidman, Bruce D. Gelb, Giorgio Colombo, Bruce R. Conklin, Brian L. Black, Benoit G. Bruneau, Nevan J. Krogan, Katherine S. Pollard, Deepak Srivastava
Cell. Author manuscript; available in PMC 2023 Mar 3.
Published in final edited form as: Cell. 2022 Mar 3; 185(5): 794–814.e30. Published online 2022 Feb 18. doi: 10.1016/j.cell.2022.01.021
PMCID:
PMC8923057
AbstractArticlePDF–2.5M
8.
Human transcription factor protein interaction networks
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5
PMCID:
PMC8828895
AbstractArticlePDF–1.7M
9.
RFWD2 Knockdown as a Blocker to Reverse the Oncogenic Role of TRIB2 in Lung Adenocarcinoma
Ruimin Hao, Jinxia Hu, Yuemei Liu, Dongmin Liang, Yan-Mei Li, Ranran Wang, Shucui Zhang, Pingyu Wang, You-Jie Li, Shuyang Xie
Front Oncol. 2021; 11: 733175. Published online 2021 Sep 27. doi: 10.3389/fonc.2021.733175
PMCID:
PMC8503262
AbstractArticlePDF–5.7M
10.
A methyltransferase‐like 14/miR‐99a‐5p/tribble 2 positive feedback circuit promotes cancer stem cell persistence and radioresistance via histone deacetylase 2‐mediated epigenetic modulation in esophageal squamous cell carcinoma
Zhenchuan Liu, Kaiqing Wu, Shaorui Gu, Wenli Wang, Shiliang Xie, Tiancheng Lu, Lei Li, Chenglai Dong, Xishi Wang, Yongxin Zhou
Clin Transl Med. 2021 Sep; 11(9): e545. Published online 2021 Sep 15. doi: 10.1002/ctm2.545
Correction in:
Clin Transl Med. 2022 Jun; 12(6): e741.
PMCID:
PMC8441142
AbstractArticlePDF–4.8M
11.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
12.
KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1
Wenxue Liu, Zhiyan Zhan, Meiying Zhang, Bowen Sun, Qiqi Shi, Fei Luo, Mingda Zhang, Weiwei Zhang, Yanli Hou, Xiuying Xiao, Yanxin Li, Haizhong Feng
Theranostics. 2021; 11(13): 6278–6292. Published online 2021 Apr 15. doi: 10.7150/thno.57455
PMCID:
PMC8120227
AbstractArticlePDF–2.7M
13.
IP6-assisted CSN-COP1 competition regulates a CRL4-ETV5 proteolytic checkpoint to safeguard glucose-induced insulin secretion
Hong Lin, Yuan Yan, Yifan Luo, Wing Yan So, Xiayun Wei, Xiaozhe Zhang, Xiaoli Yang, Jun Zhang, Yang Su, Xiuyan Yang, Bobo Zhang, Kangjun Zhang, Nan Jiang, Billy Kwok Chong Chow, Weiping Han, Fengchao Wang, Feng Rao
Nat Commun. 2021; 12: 2461. Published online 2021 Apr 28. doi: 10.1038/s41467-021-22941-3
PMCID:
PMC8080631
AbstractArticlePDF–3.1M
14.
EGF Relays Signals to COP1 and Facilitates FOXO4 Degradation to Promote Tumorigenesis
Hyun Ho Choi, Shaomin Zou, Jian‐lin Wu, Huashe Wang, Liem Phan, Kai Li, Peng Zhang, Daici Chen, Qingxin Liu, Baifu Qin, Thu Anh Thai Nguyen, Sai‐Ching J. Yeung, Lekun Fang, Mong‐Hong Lee
Adv Sci (Weinh) 2020 Oct; 7(20): 2000681. Published online 2020 Sep 23. doi: 10.1002/advs.202000681
PMCID:
PMC7578864
AbstractArticlePDF–5.0M
15.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
AbstractArticlePDF–4.8M
16.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
17.
Erk1/2 inactivation promotes a rapid redistribution of COP1 and degradation of COP1 substrates
Weiming Ouyang, Pengfei Guo, Kazuyo Takeda, Qiong Fu, Hui Fang, David M. Frucht
Proc Natl Acad Sci U S A. 2020 Feb 25; 117(8): 4078–4087. Published online 2020 Feb 10. doi: 10.1073/pnas.1913698117
PMCID:
PMC7049164
AbstractArticlePDF–1.5M
18.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch
Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9
PMCID:
PMC6981206
AbstractArticlePDF–3.7M
19.
Cryptochromes-mediated Inhibition of the CRL4Cop1-Complex Assembly Defines an Evolutionary Conserved Signaling Mechanism
Luca Rizzini, Daniel C. Levine, Mark Perelis, Joseph Bass, Clara B. Peek, Michele Pagano
Curr Biol. Author manuscript; available in PMC 2020 Jun 17.
Published in final edited form as: Curr Biol. 2019 Jun 17; 29(12): 1954–1962.e4. Published online 2019 May 30. doi: 10.1016/j.cub.2019.04.073
PMCID:
PMC6581574
AbstractArticlePDF–1.1M
20.
PRISMA: Protein Interaction Screen on Peptide Matrix Reveals Interaction Footprints and Modifications- Dependent Interactome of Intrinsically Disordered C/EBPβ
Gunnar Dittmar, Daniel Perez Hernandez, Elisabeth Kowenz-Leutz, Marieluise Kirchner, Günther Kahlert, Radoslaw Wesolowski, Katharina Baum, Maria Knoblich, Maria Hofstätter, Arnaud Muller, Jana Wolf, Ulf Reimer, Achim Leutz
iScience. 2019 Mar 29; 13: 351–370. Published online 2019 Mar 1. doi: 10.1016/j.isci.2019.02.026
PMCID:
PMC6424098
AbstractArticlePDF–11M

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