U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO Profiles

Items: 1 to 20 of 151

1.
EXTL3 and NPC1 are mammalian host factors for Autographa californica multiple nucleopolyhedrovirus infection
Yuege Huang, Hong Mei, Chunchen Deng, Wei Wang, Chao Yuan, Yan Nie, Jia-Da Li, Jia Liu
Nat Commun. 2024; 15: 7711. Published online 2024 Sep 4. doi: 10.1038/s41467-024-52193-w
PMCID:
PMC11374996
AbstractArticlePDF–2.1M
2.
ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication
Guy J. Pearson, Harriet V. Mears, Malgorzata Broncel, Ambrosius P. Snijders, David L. V. Bauer, Jeremy G. Carlton
Sci Adv. 2024 Apr 5; 10(14): eadl5012. Published online 2024 Apr 3. doi: 10.1126/sciadv.adl5012
PMCID:
PMC10990277
AbstractArticlePDF–3.9M
3.
Some aspects of the life of SARS-CoV-2 ORF3a protein in mammalian cells
Song Jiao, Pablo Miranda, Yan Li, Dragan Maric, Miguel Holmgren
Heliyon. 2023 Aug; 9(8): e18754. Published online 2023 Aug 1. doi: 10.1016/j.heliyon.2023.e18754
PMCID:
PMC10440475
AbstractArticlePDF–8.9M
4.
NPC1 plays a role in the trafficking of specific cargo to melanosomes
Alina Adriana Rus, Ioana V. Militaru, Ioana Popa, Cristian V.A. Munteanu, Livia Elena Sima, Nick Platt, Frances M. Platt, Ștefana M. Petrescu
J Biol Chem. 2023 Aug; 299(8): 105024. Published online 2023 Jul 7. doi: 10.1016/j.jbc.2023.105024
PMCID:
PMC10407747
AbstractArticlePDF–3.9M
5.
NPC1-dependent alterations in KV2.1–CaV1.2 nanodomains drive neuronal death in models of Niemann-Pick Type C disease
Maria Casas, Karl D. Murray, Keiko Hino, Nicholas C. Vierra, Sergi Simó, James S. Trimmer, Rose E. Dixon, Eamonn J. Dickson
Nat Commun. 2023; 14: 4553. Published online 2023 Jul 28. doi: 10.1038/s41467-023-39937-w
PMCID:
PMC10382591
AbstractArticlePDF–11M
6.
A Novel Small NPC1 Promoter Enhances AAV-Mediated Gene Therapy in Mouse Models of Niemann–Pick Type C1 Disease
Michael Paul Hughes, Hemanth Ramesh Nelvagal, Oliver Coombe-Tennant, Dave Smith, Claire Smith, Giulia Massaro, Laura Poupon-Bejuit, Frances Mary Platt, Ahad Abdul Rahim
Cells. 2023 Jun; 12(12): 1619. Published online 2023 Jun 13. doi: 10.3390/cells12121619
PMCID:
PMC10296851
AbstractArticlePDF–3.9M
7.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
8.
Purification and structure of luminal domain C of human Niemann–Pick C1 protein
Laura Odongo, Kaneil K. Zadrozny, William E. Diehl, Jeremy Luban, Judith M. White, Barbie K. Ganser-Pornillos, Lukas K. Tamm, Owen Pornillos
Acta Crystallogr F Struct Biol Commun. 2023 Feb 1; 79(Pt 2): 45–50. Published online 2023 Feb 2. doi: 10.1107/S2053230X23000705
PMCID:
PMC9903137
AbstractArticlePDF–723K
9.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
10.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
11.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
12.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
13.
C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy
Bing-Ru Yan, Taoyingnan Li, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell
Autophagy. 2022; 18(4): 829–840. Published online 2021 Aug 25. doi: 10.1080/15548627.2021.1960116
PMCID:
PMC9037554
AbstractArticlePDF–4.1M
14.
NPC1-mTORC1 signaling Couples Cholesterol Sensing to Organelle Homeostasis and is a Targetable Pathway in Niemann-Pick type C
Oliver B. Davis, Hijai R. Shin, Chun-Yan Lim, Emma Y. Wu, Matthew Kukurugya, Claire F. Maher, Rushika M. Perera, M. Paulina Ordonez, Roberto Zoncu
Dev Cell. Author manuscript; available in PMC 2022 Mar 14.
Published in final edited form as: Dev Cell. 2021 Feb 8; 56(3): 260–276.e7. Published online 2020 Dec 11. doi: 10.1016/j.devcel.2020.11.016
PMCID:
PMC8919971
AbstractArticlePDF–3.1M
15.
Identification of novel mutations among Iranian NPC1 patients: a bioinformatics approach to predict pathogenic mutations
Rezvan Abtahi, Parvaneh Karimzadeh, Omid Aryani, Diba Akbarzadeh, Shadab Salehpour, Alireza Rezayi, Seyed Hassan Tonekaboni, Reza Zolfaghari Emameh, Massoud Houshmand
Hereditas. 2022; 159: 8. Published online 2022 Jan 27. doi: 10.1186/s41065-022-00224-1
PMCID:
PMC8793247
AbstractArticlePDF–1.1M
16.
Annexin A6 and NPC1 regulate LDL-inducible cell migration and distribution of focal adhesions
Jaimy Jose, Monira Hoque, Johanna Engel, Syed S. Beevi, Mohamed Wahba, Mariya Ilieva Georgieva, Kendelle J. Murphy, William E. Hughes, Blake J. Cochran, Albert Lu, Francesc Tebar, Andrew J. Hoy, Paul Timpson, Kerry-Anne Rye, Carlos Enrich, Carles Rentero, Thomas Grewal
Sci Rep. 2022; 12: 596. Published online 2022 Jan 12. doi: 10.1038/s41598-021-04584-y
PMCID:
PMC8755831
AbstractArticlePDF–3.6M
17.
Patient-Specific iPSC-Derived Neural Differentiated and Hepatocyte-like Cells, Carrying the Compound Heterozygous Mutation p.V1023Sfs*15/p.G992R, Present the “Variant” Biochemical Phenotype of Niemann-Pick Type C1 Disease
Christin Völkner, Maik Liedtke, Robert Untucht, Andreas Hermann, Moritz J. Frech
Int J Mol Sci. 2021 Nov; 22(22): 12184. Published online 2021 Nov 10. doi: 10.3390/ijms222212184
PMCID:
PMC8624182
AbstractArticlePDF–24M
18.
A proteome-wide map of 20(S)-hydroxycholesterol interactors in cell membranes
Yu-Shiuan Cheng, Tianyi Zhang, Xiang Ma, Sarida Pratuangtham, Grace C. Zhang, Alexander A. Ondrus, Amirhossein Mafi, Brett Lomenick, Jeffrey J. Jones, Alison E. Ondrus
Nat Chem Biol. Author manuscript; available in PMC 2022 May 19.
Published in final edited form as: Nat Chem Biol. 2021 Dec; 17(12): 1271–1280. Published online 2021 Nov 19. doi: 10.1038/s41589-021-00907-2
PMCID:
PMC8607797
AbstractArticlePDF–2.2M
19.
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery
Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo
Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396
PMCID:
PMC8552907
AbstractArticlePDF–3.9M
20.
Anaplasma phagocytophilum Hijacks Flotillin and NPC1 Complex To Acquire Intracellular Cholesterol for Proliferation, Which Can Be Inhibited with Ezetimibe
Weiyan Huang, Qingming Xiong, Mingqun Lin, Yasuko Rikihisa
mBio. 2021 Sep-Oct; 12(5): e02299-21. Published online 2021 Sep 21. doi: 10.1128/mBio.02299-21
PMCID:
PMC8546544
AbstractArticlePDF–6.5M

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

You are here: NCBI > Literature > PubMed Central (PMC)
Support Center