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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 103940882.

Microglial expression of CD83 governs cellular activation and restrains neuroinflammation in experimental autoimmune encephalomyelitis

Pia Sinner, Katrin Peckert-Maier, Hashem Mohammadian, Christine Kuhnt, Christina Draßner, Vasiliki Panagiotakopoulou, Simon Rauber, Mathias Linnerbauer, Zhana Haimon, Dmytro Royzman, Deborah Kronenberg-Versteeg, Andreas Ramming, Alexander Steinkasserer, Andreas B. Wild

Nat Commun. 2023; 14: 4601. Published online 2023 Aug 1. doi: 10.1038/s41467-023-40370-2

PMCID:: PMC10394088

Abstract Article PDF–5.0M

Select item 99755603.

CD83 expressed by macrophages is an important immune checkpoint molecule for the resolution of inflammation

Katrin Peckert-Maier, Pia Langguth, Astrid Strack, Lena Stich, Petra Mühl-Zürbes, Christine Kuhnt, Christina Drassner, Elisabeth Zinser, Marius Wrage, Jochen Mattner, Alexander Steinkasserer, Dmytro Royzman, Andreas B. Wild

Front Immunol. 2023; 14: 1085742. Published online 2023 Feb 15. doi: 10.3389/fimmu.2023.1085742

PMCID:: PMC9975560

Abstract Article PDF–25M

Select item 93937264.

The soluble CD83 protein prevents bone destruction by inhibiting the formation of osteoclasts and inducing resolution of inflammation in arthritis

Dmytro Royzman, Darja Andreev, Lena Stich, Katrin Peckert-Maier, Andreas B. Wild, Elisabeth Zinser, Petra Mühl-Zürbes, Evan Jones, Susanne Adam, Silke Frey, Maximilian Fuchs, Meik Kunz, Tobias Bäuerle, Lisa Nagel, Georg Schett, Aline Bozec, Alexander Steinkasserer

Front Immunol. 2022; 13: 936995. Published online 2022 Aug 8. doi: 10.3389/fimmu.2022.936995

PMCID:: PMC9393726

Abstract Article PDF–5.1M

Select item 88661885.

Anti-Mouse CD83 Monoclonal Antibody Targeting Mature Dendritic Cells Provides Protection Against Collagen Induced Arthritis

Pablo A. Silveira, Fiona Kupresanin, Adelina Romano, Wei-Hsun Hsu, Tsun-Ho Lo, Xinsheng Ju, Hsiao-Ting Chen, Helen Roberts, Daniel G. Baker, Georgina J. Clark

Front Immunol. 2022; 13: 784528. Published online 2022 Feb 10. doi: 10.3389/fimmu.2022.784528

PMCID:: PMC8866188

Abstract Article PDF–6.6M

Select item 84609886.

Intestinal Epithelial Cell-Derived CD83 Contributes to Regulatory T-Cell Generation and Inhibition of Food Allergy

Yong Yu, Qiao-Ruo Jin, Yang Mi, Jiang-Qi Liu, Zhi-Qiang Liu, Shuai Wang, Zhi-Gang Liu, Ping-Chang Yang, Peng-Yuan Zheng

J Innate Immun. 2021 Sep; 13(5): 295–305. Published online 2021 Jun 28. doi: 10.1159/000515332

PMCID:: PMC8460988

Abstract Article PDF–1.1M

Select item 77307497.

CD83 expression regulates antibody production in response to influenza A virus infection

Madhav Akauliya, Avishekh Gautam, Sony Maharjan, Byoung Kwon Park, Jinsoo Kim, Hyung-Joo Kwon

Virol J. 2020; 17: 194. Published online 2020 Dec 10. doi: 10.1186/s12985-020-01465-0

PMCID:: PMC7730749

Abstract Article PDF–2.4M

Select item 74159918.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 68243079.

CD83 orchestrates immunity toward self and non-self in dendritic cells

Andreas B. Wild, Lena Krzyzak, Katrin Peckert, Lena Stich, Christine Kuhnt, Alina Butterhof, Christine Seitz, Jochen Mattner, Niklas Grüner, Maximilian Gänsbauer, Martin Purtak, Didier Soulat, Thomas H. Winkler, Lars Nitschke, Elisabeth Zinser, Alexander Steinkasserer

JCI Insight. 2019 Oct 17; 4(20): e126246. Published online 2019 Oct 17. doi: 10.1172/jci.insight.126246

PMCID:: PMC6824307

Abstract Article PDF–3.8M

Select item 645529410.

Soluble CD83 Triggers Resolution of Arthritis and Sustained Inflammation Control in IDO Dependent Manner

Dmytro Royzman, Darja Andreev, Lena Stich, Manfred Rauh, Tobias Bäuerle, Stephan Ellmann, Louis Boon, Markus Kindermann, Katrin Peckert, Aline Bozec, Georg Schett, Alexander Steinkasserer, Elisabeth Zinser

Front Immunol. 2019; 10: 633. Published online 2019 Apr 2. doi: 10.3389/fimmu.2019.00633

PMCID:: PMC6455294

Abstract Article PDF–7.4M

Select item 612444311.

CD83 expression is essential for Treg cell differentiation and stability

Marina Doebbeler, Christina Koenig, Lena Krzyzak, Christine Seitz, Andreas Wild, Thomas Ulas, Kevin Baßler, Dmitry Kopelyanskiy, Alina Butterhof, Christine Kuhnt, Simon Kreiser, Lena Stich, Elisabeth Zinser, Ilka Knippertz, Stefan Wirtz, Christin Riegel, Petra Hoffmann, Matthias Edinger, Lars Nitschke, Thomas Winkler, Joachim L. Schultze, Alexander Steinkasserer, Matthias Lechmann

JCI Insight. 2018 Jun 7; 3(11): e99712. Published online 2018 Jun 7. doi: 10.1172/jci.insight.99712

PMCID:: PMC6124443

Abstract Article PDF–3.1M

Select item 529582112.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 509866513.

Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line

Van Trung Chu, Robin Graf, Tristan Wirtz, Timm Weber, Jeremy Favret, Xun Li, Kerstin Petsch, Ngoc Tung Tran, Michael H. Sieweke, Claudia Berek, Ralf Kühn, Klaus Rajewsky

Proc Natl Acad Sci U S A. 2016 Nov 1; 113(44): 12514–12519. Published online 2016 Oct 11. doi: 10.1073/pnas.1613884113

PMCID:: PMC5098665

Abstract Article PDF–1.5M

Select item 499508614.

Thymic CD4 T cell selection requires attenuation of March8-mediated MHCII turnover in cortical epithelial cells through CD83

Julia von Rohrscheidt, Elisabetta Petrozziello, Jelena Nedjic, Christine Federle, Lena Krzyzak, Hidde L. Ploegh, Satoshi Ishido, Alexander Steinkasserer, Ludger Klein

J Exp Med. 2016 Aug 22; 213(9): 1685–1694. doi: 10.1084/jem.20160316

PMCID:: PMC4995086

Abstract Article PDF–2.1M

Select item 499508515.

Ubiquitin ligase MARCH 8 cooperates with CD83 to control surface MHC II expression in thymic epithelium and CD4 T cell selection

Haiyin Liu, Reema Jain, Jing Guan, Vivian Vuong, Satoshi Ishido, Nicole L. La Gruta, Daniel H. Gray, Jose A. Villadangos, Justine D. Mintern

J Exp Med. 2016 Aug 22; 213(9): 1695–1703. doi: 10.1084/jem.20160312

PMCID:: PMC4995085

Abstract Article PDF–1.8M

Select item 488636116.

Ubiquitin-mediated fluctuations in MHC class II facilitate efficient germinal center B cell responses

Oliver Bannard, Simon J. McGowan, Jonatan Ersching, Satoshi Ishido, Gabriel D. Victora, Jeoung-Sook Shin, Jason G. Cyster

J Exp Med. 2016 May 30; 213(6): 993–1009. doi: 10.1084/jem.20151682

PMCID:: PMC4886361

Abstract Article PDF–2.5M

Select item 438043817.

Expression of the Immunoglobulin Superfamily Cell Adhesion Molecules in the Developing Spinal Cord and Dorsal Root Ganglion

Zirong Gu, Fumiyasu Imai, In Jung Kim, Hiroko Fujita, Kei ichi Katayama, Kensaku Mori, Yoshihiro Yoshihara, Yutaka Yoshida

PLoS One. 2015; 10(3): e0121550. Published online 2015 Mar 31. doi: 10.1371/journal.pone.0121550

PMCID:: PMC4380438

Abstract Article PDF–36M

Select item 432697618.

Dendritic cell CD83 homotypic interactions regulate inflammation and promote mucosal homeostasis

J M Bates, K Flanagan, L Mo, N Ota, J Ding, S Ho, S Liu, M Roose-Girma, S Warming, L Diehl

Mucosal Immunol. 2015 Mar; 8(2): 414–428. Published online 2014 Sep 10. doi: 10.1038/mi.2014.79

PMCID:: PMC4326976

Abstract Article PDF–1.2M

Select item 430011019.

The Transmembrane E3 Ligase GRAIL Ubiquitinates and Degrades CD83 on CD4 T Cells

Leon L. Su, Hideyuki Iwai, Jack T. Lin, C. Garrison Fathman

J Immunol. Author manuscript; available in PMC 2015 Jan 20.

Published in final edited form as: J Immunol. 2009 Jul 1; 183(1): 438–444. doi: 10.4049/jimmunol.0900204

PMCID:: PMC4300110

Abstract Article PDF–1.7M

Select item 396495520.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

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