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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 102847942.

RNF128 regulates neutrophil infiltration and myeloperoxidase functions to prevent acute lung injury

Pei-Yao Liu, Chih-Yuan Chen, Yu-Lung Lin, Chien-Ming Lin, Wen-Chiuan Tsai, Yu-Ling Tsai, Gu-Jiun Lin, Yu-Guang Chen, Shih-Yun Wang, Rui-Nong Sun, Yu-Chuan Huang, Hung Chang, Ying-Chuan Chen

Cell Death Dis. 2023 Jun; 14(6): 369. Published online 2023 Jun 21. doi: 10.1038/s41419-023-05890-1

PMCID:: PMC10284794

Abstract Article PDF–5.8M

Select item 102266803.

Gut commensal bacteria enhance pathogenesis of a tumorigenic murine retrovirus

Jessica Spring, Aly A. Khan, Sophie Lara, Kelly O’Grady, Jessica Wilks, Sandeep Gurbuxani, Steven Erickson, Michael Fischbach, Amy Jacobson, Alexander Chervonsky, Tatyana Golovkina

Cell Rep. Author manuscript; available in PMC 2023 May 29.

Published in final edited form as: Cell Rep. 2022 Sep 13; 40(11): 111341. doi: 10.1016/j.celrep.2022.111341

PMCID:: PMC10226680

Abstract Article PDF–1.1M

Select item 97739904.

How GRAIL controls Treg function to maintain self-tolerance

C. Garrison Fathman, Linda Yip, Diana Gómez-Martín, Mang Yu, Christine M. Seroogy, Clarence R. Hurt, Jack T. Lin, Jennifer A. Jenks, Kari C. Nadeau, Luis Soares

Front Immunol. 2022; 13: 1046631. Published online 2022 Dec 8. doi: 10.3389/fimmu.2022.1046631

PMCID:: PMC9773990

Abstract Article PDF–6.1M

Select item 88150325.

Alx1 Deficient Mice Recapitulate Craniofacial Phenotype and Reveal Developmental Basis of ALX1-Related Frontonasal Dysplasia

Paul P. R. Iyyanar, Zhaoming Wu, Yu Lan, Yueh-Chiang Hu, Rulang Jiang

Front Cell Dev Biol. 2022; 10: 777887. Published online 2022 Jan 21. doi: 10.3389/fcell.2022.777887

PMCID:: PMC8815032

Abstract Article PDF–3.6M

Select item 81172096.

Cbl-b deficiency prevents functional but not phenotypic T cell anergy

Trang T.T. Nguyen, Zhi-En Wang, Lin Shen, Andrew Schroeder, Walter Eckalbar, Arthur Weiss

J Exp Med. 2021 Jul 5; 218(7): e20202477. Published online 2021 May 11. doi: 10.1084/jem.20202477

PMCID:: PMC8117209

Abstract Article PDF–6.4M

Select item 79978937.

E3 ubiquitin ligase Grail promotes hepatic steatosis through Sirt1 inhibition

Pei-Yao Liu, Cheng-Cheung Chen, Chia-Ying Chin, Te-Jung Liu, Wen-Chiuan Tsai, Jian-Liang Chou, Chuan-Yu Huang, Yu-Guang Chen, Ying-Chuan Chen

Cell Death Dis. 2021 Apr; 12(4): 323. Published online 2021 Mar 26. doi: 10.1038/s41419-021-03608-9

PMCID:: PMC7997893

Abstract Article PDF–3.7M

Select item 66023588.

The molecular anatomy of mammalian upper lip and primary palate fusion at single cell resolution

Hong Li, Kenneth L. Jones, Joan E. Hooper, Trevor Williams

Development. 2019 Jun 15; 146(12): dev174888. Published online 2019 Jun 17. doi: 10.1242/dev.174888

PMCID:: PMC6602358

Abstract Article

Select item 63015729.

Macrophage expression of E3 ubiquitin ligase Grail protects mice from lipopolysaccharide-induced hyperinflammation and organ injury

Chih-Chin Shih, Pei-Yao Liu, Jye-Hann Chen, Mei-Hui Liao, Chih-Ming Hsieh, Shuk-Man Ka, Chin-Chen Wu, Hui-Tsu Lin, Ti-Hui Wu, Ying-Chuan Chen

PLoS One. 2018; 13(12): e0208279. Published online 2018 Dec 20. doi: 10.1371/journal.pone.0208279

PMCID:: PMC6301572

Abstract Article PDF–2.0M

Select item 625072010.

Grail attenuates influenza A virus infection and pathogenesis by inhibiting viral nucleoprotein

Hui-Tsu Lin, Cheng-Cheung Chen, Pei-Yao Liu, Hsueh-Ling Wu, Ti-Hui Wu, Chih-Heng Huang, Ying-Chuan Chen

Sci Rep. 2018; 8: 17242. Published online 2018 Nov 22. doi: 10.1038/s41598-018-35722-8

PMCID:: PMC6250720

Abstract Article PDF–3.3M

Select item 594341011.

Grail is involved in adipocyte differentiation and diet-induced obesity

Peiyao Liu, Poshiuan Hsieh, Huitsu Lin, Tejung Liu, Hsuehling Wu, Chengcheung Chen, Yingchuan Chen

Cell Death Dis. 2018 May; 9(5): 525. Published online 2018 May 9. doi: 10.1038/s41419-018-0596-8

PMCID:: PMC5943410

Abstract Article PDF–3.3M

Select item 555279712.

Absence of Grail promotes CD8⁺ T cell anti-tumour activity

Cara Haymaker, Yi Yang, Junmei Wang, Qiang Zou, Anupama Sahoo, Andrei Alekseev, Divyendu Singh, Krit Ritthipichai, Yared Hailemichael, Oanh N. Hoang, Hong Qin, Kimberly S. Schluns, Tiejun Wang, Willem W. Overwijk, Shao-Cong Sun, Chantale Bernatchez, Larry W. Kwak, Sattva S. Neelapu, Roza Nurieva

Nat Commun. 2017; 8: 239. Published online 2017 Aug 10. doi: 10.1038/s41467-017-00252-w

PMCID:: PMC5552797

Abstract Article PDF–1.9M

Select item 549074513.

Neuropeptide FF increases M2 activation and self-renewal of adipose tissue macrophages

Syed F. Hassnain Waqas, Anh Cuong Hoang, Ya-Tin Lin, Grace Ampem, Hind Azegrouz, Lajos Balogh, Julianna Thuróczy, Jin-Chung Chen, Ivan C. Gerling, Sorim Nam, Jong-Seok Lim, Juncal Martinez-Ibañez, José T. Real, Stephan Paschke, Raphaëlle Quillet, Safia Ayachi, Frédéric Simonin, E. Marion Schneider, Jacqueline A. Brinkman, Dudley W. Lamming, Christine M. Seroogy, Tamás Röszer

J Clin Invest. 2017 Jun 30; 127(7): 2842–2854. Published online 2017 Jun 5. doi: 10.1172/JCI90152

Correction in:: J Clin Invest. 2017 Sep 1; 127(9): 3559.

PMCID:: PMC5490745

Abstract Article PDF–2.1M

Select item 528961114.

GRAIL and Otubain-1 are Related to T Cell Hyporesponsiveness during Trypanosoma cruzi Infection

Cinthia C. Stempin, Jorge D. Rojas Marquez, Yamile Ana, Fabio M. Cerban

PLoS Negl Trop Dis. 2017 Jan; 11(1): e0005307. Published online 2017 Jan 23. doi: 10.1371/journal.pntd.0005307

PMCID:: PMC5289611

Abstract Article PDF–1.3M

Select item 510080815.

Grail controls Th2 cell development by targeting STAT6 for degradation

Anupama Sahoo, Andrei Alekseev, Lidiya Obertas, Roza Nurieva

Nat Commun. Author manuscript; available in PMC 2016 Nov 8.

Published in final edited form as: Nat Commun. 2014 Aug 22; 5: 4732. Published online 2014 Aug 22. doi: 10.1038/ncomms5732

PMCID:: PMC5100808

Abstract Article PDF–2.0M

Select item 461808616.

The Interleukin-2-mTORc1 Axis Defines the Reciprocal Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells

John P. Ray, Matthew M. Staron, Justin A. Shyer, Ping-Chih Ho, Heather D. Marshall, Simon M. Gray, Brian J. Laidlaw, Koichi Araki, Rafi Ahmed, Susan M. Kaech, Joe Craft

Immunity. Author manuscript; available in PMC 2016 Oct 20.

Published in final edited form as: Immunity. 2015 Oct 20; 43(4): 690–702. Published online 2015 Sep 22. doi: 10.1016/j.immuni.2015.08.017