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Select item 111140741.

Probing Protein Structural Changes in Alzheimer’s Disease via Quantitative Cross-linking Mass Spectrometry

Zexin Zhu, Xiaofang Zhong, Bin Wang, Haiyan Lu, Lingjun Li

Anal Chem. Author manuscript; available in PMC 2024 May 23.

Published in final edited form as: Anal Chem. 2024 May 14; 96(19): 7506–7515. Published online 2024 May 1. doi: 10.1021/acs.analchem.4c00182

PMCID:: PMC11114074

Abstract Article PDF–1.6M

Select item 110364492.

Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn’s disease and leads to impaired CFB cleavage and phagocytosis

Marzieh Akhlaghpour, Talin Haritunians, Shyam K More, Lisa S Thomas, Dalton T Stamps, Shishir Dube, Dalin Li, Shaohong Yang, Carol J Landers, Emebet Mengesha, Hussein Hamade, Ramachandran Murali, Alka A Potdar, Andrea J Wolf, Gregory J Botwin, Michelle Khrom, International IBD Genetics Consortium, Ashwin N Ananthakrishnan, William A Faubion, Bana Jabri, Sergio A Lira, Rodney D Newberry, Robert S Sandler, R Balfour Sartor, Ramnik J Xavier, Steven R Brant, Judy H Cho, Richard H Duerr, Mark G Lazarev, John D Rioux, L Philip Schumm, Mark S Silverberg, Karen Zaghiyan, Phillip Fleshner, Gil Y Melmed, Eric A Vasiliauskas, Christina Ha, Shervin Rabizadeh, Gaurav Syal, Nirupama N Bonthala, David A Ziring, Stephan R Targan, Millie D Long, Dermot P B McGovern, Kathrin S Michelsen

Gut. Author manuscript; available in PMC 2024 Nov 1.

Published in final edited form as: Gut. 2023 Nov; 72(11): 2068–2080. Published online 2023 Apr 20. doi: 10.1136/gutjnl-2023-329689

PMCID:: PMC11036449

Abstract Article PDF–1.9M

Select item 107610053.

Prepregnancy obesity and complement system activation in early pregnancy and the subsequent development of preeclampsia

Anne M. Lynch, Robert H. Eckel, James R. Murphy, Ronald S. Gibbs, Nancy A. West, Patricia C. Giclas, Jane E. Salmon, V. Michael Holers

Am J Obstet Gynecol. Author manuscript; available in PMC 2024 Jan 2.

Published in final edited form as: Am J Obstet Gynecol. 2012 May; 206(5): 428.e1–428.e4288. Published online 2012 Mar 7. doi: 10.1016/j.ajog.2012.02.035

PMCID:: PMC10761005

Abstract Article PDF–1.0M

Select item 102794694.

Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein

Sean A. Burnap, Ana Maria Ortega-Prieto, Jose M. Jimenez-Guardeño, Hashim Ali, Kaloyan Takov, Matthew Fish, Manu Shankar-Hari, Mauro Giacca, Michael H. Malim, Manuel Mayr

Mol Cell Proteomics. 2023 Aug; 22(8): 100600. Published online 2023 Jun 19. doi: 10.1016/j.mcpro.2023.100600

PMCID:: PMC10279469

Abstract Article PDF–3.2M

Select item 101516155.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 100395116.

Study of FOXO1-interacting proteins using TurboID-based proximity labeling technology

Yanting Su, Yuanyuan Guo, Jieyu Guo, Ting Zeng, Ting Wang, Wu Liu

BMC Genomics. 2023; 24: 146. Published online 2023 Mar 24. doi: 10.1186/s12864-023-09238-z

PMCID:: PMC10039511

Abstract Article PDF–2.0M

Select item 99286807.

Targeted genotyping of COVID-19 patients reveals a signature of complement C3 and factor B coding SNPs associated with severe infection

Stefanos A. Tsiftsoglou, Eleni Gavriilaki, Tasoula Touloumenidou, Evaggelia-Evdoxia Koravou, Maria Koutra, Penelope Georgia Papayanni, Vassiliki Karali, Apostolia Papalexandri, Christos Varelas, Fani Chatzopoulou, Maria Chatzidimitriou, Dimitrios Chatzidimitriou, Anastasia Veleni, Evdoxia Rapti, Ioannis Kioumis, Evaggelos Kaimakamis, Milly Bitzani, Dimitrios T. Boumpas, Argyris Tsantes, Damianos Sotiropoulos, Anastasia Papadopoulou, Ioanna Sakellari, Styliani Kokoris, Achilles Anagnostopoulos

Immunobiology. 2023 Mar; 228(2): 152351. Published online 2023 Feb 15. doi: 10.1016/j.imbio.2023.152351

PMCID:: PMC9928680

Abstract Article PDF–2.2M

Select item 96062158.

Functional variant rs12614 in CFB confers a low risk of IgA nephropathy by attenuating complement alternative pathway activation in Han Chinese

Dian-Chun Shi, Shao-Zhen Feng, Zhong Zhong, Lu Cai, Meng Wang, Dong-Ying Fu, Xue-Qing Yu, Ming Li

Front Immunol. 2022; 13: 973169. Published online 2022 Oct 13. doi: 10.3389/fimmu.2022.973169

Correction in:: Front Immunol. 2022; 13: 1098003.

PMCID:: PMC9606215

Abstract Article PDF–7.4M

Select item 95973849.

Evolutionary trajectory of receptor binding specificity and promiscuity of the spike protein of SARS‐CoV‐2

Cyril Planchais, Alejandra Reyes‐Ruiz, Robin Lacombe, Alessandra Zarantonello, Maxime Lecerf, Margot Revel, Lubka T. Roumenina, Boris P. Atanasov, Hugo Mouquet, Jordan D. Dimitrov

Protein Sci. 2022 Nov; 31(11): e4447. Published online 2022 Oct 26. doi: 10.1002/pro.4447

PMCID:: PMC9597384

Abstract Article PDF–5.4M

Select item 927928510.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 881013211.

The prognostic value of plasma complement factor B (CFB) in thyroid carcinoma

Pu Wu, Jinyuan Shi, Wei Sun, Hao Zhang

Bioengineered. 2021; 12(2): 12854–12866. Published online 2021 Dec 16. doi: 10.1080/21655979.2021.2005745

PMCID:: PMC8810132

Abstract Article PDF–3.4M

Select item 858183112.

Association of genetic variants rs641153 (CFB), rs2230199 (C3), and rs1410996 (CFH) with age-related macular degeneration in a Brazilian population

Jamil M Neto, Marina GM Viturino, Galina Ananina, Flávia F Bajano, Sueli M da S Costa, Alicia B Roque, Gessica FS Borges, Raissa Franchi, Priscila HH Rim, Flávio M Medina, Fernando F Costa, Mônica B de Melo, José PC de Vasconcellos

Exp Biol Med (Maywood) 2021 Nov; 246(21): 2290–2296. Published online 2021 Jul 7. doi: 10.1177/15353702211024543

PMCID:: PMC8581831

Abstract Article PDF–326K

Select item 856647313.

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma

Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim

Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6

PMCID:: PMC8566473

Abstract Article PDF–2.7M

Select item 833887014.

Complement factor B regulates cellular senescence and is associated with poor prognosis in pancreatic cancer

Reiri Shimazaki, Shigetsugu Takano, Mamoru Satoh, Mamoru Takada, Yoji Miyahara, Kosuke Sasaki, Hideyuki Yoshitomi, Shingo Kagawa, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Kazuyuki Sogawa, Shinichiro Motohashi, Fumio Nomura, Masaru Miyazaki, Masayuki Ohtsuka

Cell Oncol (Dordr) 2021; 44(4): 937–950. Published online 2021 Jun 1. doi: 10.1007/s13402-021-00614-z

PMCID:: PMC8338870

Abstract Article PDF–4.5M

Select item 821662215.

Inherited Kidney Complement Diseases

Mathieu Lemaire, Damien Noone, Anne-Laure Lapeyraque, Christoph Licht, Véronique Frémeaux-Bacchi

Clin J Am Soc Nephrol. 2021 Jun; 16(6): 942–956. Published online 2021 Jun. doi: 10.2215/CJN.11830720

PMCID:: PMC8216622

Abstract Article

Select item 816503016.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011