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Items: 1 to 20 of 25

1.
Bik promotes proteasomal degradation to control low-grade inflammation
Yohannes A. Mebratu, Jane T. Jones, Congjian Liu, Zerihun H. Negasi, Mizanur Rahman, Joselyn Rojas-Quintero, George T. O’Connor, Wei Gao, Josée Dupuis, Michael H. Cho, Augusto A. Litonjua, Scott Randell, Yohannes Tesfaigzi
J Clin Invest. 2024 Feb 15; 134(4): e170594. Published online 2023 Dec 19. doi: 10.1172/JCI170594
PMCID:
PMC10866658
AbstractArticlePDF–7.5M
2.
Reduced Bik expression drives low-grade airway inflammation and increased risk for COPD in females
Irina Petrache, David W.H. Riches
J Clin Invest. 2024 Feb 15; 134(4): e177753. Published online 2024 Feb 15. doi: 10.1172/JCI177753
PMCID:
PMC10866644
AbstractArticlePDF–1.1M
3.
Independent role of caspases and Bik in augmenting influenza A virus replication in airway epithelial cells and mice
Sourabh Soni, Stephanie Walton-Filipczak, Richard S. Nho, Yohannes Tesfaigzi, Yohannes A. Mebratu
Virol J. 2023; 20: 78. Published online 2023 Apr 24. doi: 10.1186/s12985-023-02027-w
Correction in:
Virol J. 2023; 20: 95.
PMCID:
PMC10127399
AbstractArticlePDF–2.8M
4.
Endoplasmic reticulum protein BIK binds to and inhibits mitochondria-localized antiapoptotic proteins
Elizabeth J. Osterlund, Nehad Hirmiz, Dang Nguyen, James M. Pemberton, Qiyin Fang, David W. Andrews
J Biol Chem. 2023 Feb; 299(2): 102863. Published online 2023 Jan 2. doi: 10.1016/j.jbc.2022.102863
PMCID:
PMC9932132
AbstractArticlePDF–5.5M
5.
Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death
Farrah El-Saafin, Maria I. Bergamasco, Yunshun Chen, Rose E. May, Prabagaran Esakky, Soroor Hediyeh-zadeh, Mathew Dixon, Stephen Wilcox, Melissa J. Davis, Andreas Strasser, Gordon K. Smyth, Tim Thomas, Anne K. Voss
Cell Death Differ. 2022 May; 29(5): 1013–1027. Published online 2022 Mar 31. doi: 10.1038/s41418-022-00982-5
PMCID:
PMC9091217
AbstractArticlePDF–7.2M
6.
Tip60- and sirtuin 2-regulated MARCKS acetylation and phosphorylation are required for diabetic embryopathy
Penghua Yang, Cheng Xu, E. Albert Reece, Xi Chen, Jianxiang Zhong, Min Zhan, Deborah J. Stumpo, Perry J. Blackshear, Peixin Yang
Nat Commun. 2019; 10: 282. Published online 2019 Jan 17. doi: 10.1038/s41467-018-08268-6
PMCID:
PMC6336777
AbstractArticlePDF–6.8M
7.
IL-13 in LPS-Induced Inflammation Causes Bcl-2 Expression to Sustain Hyperplastic Mucous cells
Hitendra S. Chand, Jennifer F. Harris, Yohannes Tesfaigzi
Sci Rep. 2018; 8: 436. Published online 2018 Jan 11. doi: 10.1038/s41598-017-18884-9
PMCID:
PMC5765145
AbstractArticlePDF–1.7M
8.
Bik reduces hyperplastic cells by increasing Bak and activating DAPk1 to juxtapose ER and mitochondria
Yohannes A. Mebratu, Ivan Leyva-Baca, Marc G. Wathelet, Neal Lacey, Hitendra S. Chand, Augustine M. K. Choi, Yohannes Tesfaigzi
Nat Commun. 2017; 8: 803. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00975-w
PMCID:
PMC5630627
AbstractArticlePDF–3.5M
9.
Osteopontin-stimulated apoptosis in cardiac myocytes involves oxidative stress and mitochondrial death pathway: role of a pro-apoptotic protein BIK
Suman Dalal, Qinqin Zha, Mahipal Singh, Krishna Singh
Mol Cell Biochem. Author manuscript; available in PMC 2017 Aug 17.
Published in final edited form as: Mol Cell Biochem. 2016 Jul; 418(1-2): 1–11. Published online 2016 Jun 4. doi: 10.1007/s11010-016-2725-y
PMCID:
PMC5559874
AbstractArticlePDF–746K
10.
Bik Mediates Caspase-Dependent Cleavage of Viral Proteins to Promote Influenza A Virus Infection
Yohannes A. Mebratu, Jennifer Tipper, Hitendra S. Chand, Stephanie Walton, Kevin S. Harrod, Yohannes Tesfaigzi
Am J Respir Cell Mol Biol. 2016 May; 54(5): 664–673. doi: 10.1165/rcmb.2015-0133OC
PMCID:
PMC4942193
AbstractArticlePDF–1.4M
11.
Targeting SQSTM1/p62 Induces Cargo Loading Failure and Converts Autophagy to Apoptosis via NBK/Bik
Shuang Chen, Liang Zhou, Yu Zhang, Yun Leng, Xin-Yan Pei, Hui Lin, Richard Jones, Robert Z. Orlowski, Yun Dai, Steven Grant
Mol Cell Biol. 2014 Sep; 34(18): 3435–3449. doi: 10.1128/MCB.01383-13
PMCID:
PMC4135623
AbstractArticlePDF–4.1M
12.
Src tyrosine kinase inhibits apoptosis through the Erk1/2- dependent degradation of the death accelerator Bik
J Lopez, C Hesling, J Prudent, N Popgeorgiev, R Gadet, I Mikaelian, R Rimokh, G Gillet, P Gonzalo
Cell Death Differ. 2012 Sep; 19(9): 1459–1469. Published online 2012 Mar 2. doi: 10.1038/cdd.2012.21
PMCID:
PMC3422470
AbstractArticlePDF–875K
13.
Neither loss of Bik alone, nor combined loss of Bik and Noxa, accelerate murine lymphoma development or render lymphoma cells resistant to DNA damaging drugs
L Happo, B Phipson, G K Smyth, A Strasser, C L Scott
Cell Death Dis. 2012 May; 3(5): e306. Published online 2012 May 10. doi: 10.1038/cddis.2012.42
PMCID:
PMC3366076
AbstractArticlePDF–814K
14.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
15.
BikDD Eliminates Breast Cancer Initiating Cells and Synergizes with Lapatinib for Breast Cancer Treatment
Jing-Yu Lang, Jennifer L. Hsu, Funda Meric-Bernstam, Chun-Ju Chang, Qingfei Wang, Yi Bao, Hirohito Yamaguchi, Xiaoming Xie, Wendy A. Woodward, Dihua Yu, Gabriel N. Hortobagyi, Mien-Chie Hung
Cancer Cell. Author manuscript; available in PMC 2012 Sep 13.
Published in final edited form as: Cancer Cell. 2011 Sep 13; 20(3): 341–356. doi: 10.1016/j.ccr.2011.07.017
PMCID:
PMC3172580
AbstractArticlePDF–4.2M
16.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
17.
BH3-only protein BIK induces caspase-independent cell death with autophagic features in Bcl-2 null cells
R Rashmi, SG Pillai, S Vijayalingam, J Ryerse, G Chinnadurai
Oncogene. Author manuscript; available in PMC 2010 Aug 25.
Published in final edited form as: Oncogene. 2008 Feb 28; 27(10): 1366–1375. Published online 2007 Sep 17. doi: 10.1038/sj.onc.1210783
PMCID:
PMC2928058
AbstractArticlePDF–775K
18.
The BH3-only protein Bik/Blk/Nbk inhibits nuclear translocation of activated ERK1/2 to mediate IFNγ-induced cell death
Yohannes A. Mebratu, Burton F. Dickey, Chris Evans, Yohannes Tesfaigzi
J Cell Biol. 2008 Nov 3; 183(3): 429–439. doi: 10.1083/jcb.200801186
PMCID:
PMC2575785
AbstractArticlePDF–1.7M
19.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
20.
Concomitant loss of proapoptotic BH3-only Bcl-2 antagonists Bik and Bim arrests spermatogenesis
Leigh Coultas, Philippe Bouillet, Kate L Loveland, Sarah Meachem, Harris Perlman, Jerry M Adams, Andreas Strasser
EMBO J. 2005 Nov 16; 24(22): 3963–3973. Published online 2005 Nov 3. doi: 10.1038/sj.emboj.7600857
PMCID:
PMC1283956
AbstractArticlePDF–773K

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