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Select item 115739871.

TET3 regulates terminal cell differentiation at the metabolic level

Isabel Mulet, Carmen Grueso-Cortina, Mireia Cortés-Cano, Daniela Gerovska, Guangming Wu, Stefania Alexandra Iakab, Daniel Jimenez-Blasco, Andrea Curtabbi, Pablo Hernansanz-Agustín, Harmony Ketchum, Israel Manjarrés-Raza, F. Thomas Wunderlich, Juan Pedro Bolaños, Meelad M. Dawlaty, Carsten Hopf, José Antonio Enríquez, Marcos J. Araúzo-Bravo, Natalia Tapia

Nat Commun. 2024; 15: 9749. Published online 2024 Nov 18. doi: 10.1038/s41467-024-54044-0

PMCID:: PMC11573987

Abstract Article PDF–4.2M

Select item 113333792.

Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for β-Cell Function During Aging

Jose A. Ortiz, Nadiah Ghazalli, Kassandra Lopez, Jeffrey Rawson, Erika M. McCown, Eunjin Oh, Jose M. Irimia, Kevin Jou, Jacob Mares, Min-Hsuan Chen, Xiwei Wu, Heather N. Zook, Janine C. Quijano, Neslihan Erdem, Anahy Lizarraga, Fouad Kandeel, Patrick T. Fueger, Debbie C. Thurmond, Hsun Teresa Ku

Diabetes. 2024 Sep; 73(9): 1447–1461. Published online 2024 Jun 21. doi: 10.2337/db23-0490

PMCID:: PMC11333379

Abstract Article PDF–209M

Select item 112693033.

MicroRNA-7 regulates endocrine progenitor delamination and endocrine cell mass in developing pancreatic islets

Eva Kane, Tracy C.S. Mak, Mathieu Latreille

iScience. 2024 Jul 19; 27(7): 110332. Published online 2024 Jun 20. doi: 10.1016/j.isci.2024.110332

PMCID:: PMC11269303

Abstract Article PDF–5.7M

Select item 110041804.

Decoding spatiotemporal transcriptional dynamics and epithelial fibroblast crosstalk during gastroesophageal junction development through single cell analysis

Naveen Kumar, Pon Ganish Prakash, Christian Wentland, Shilpa Mary Kurian, Gaurav Jethva, Volker Brinkmann, Hans-Joachim Mollenkopf, Tobias Krammer, Christophe Toussaint, Antoine-Emmanuel Saliba, Matthias Biebl, Christian Jürgensen, Bertram Wiedenmann, Thomas F. Meyer, Rajendra Kumar Gurumurthy, Cindrilla Chumduri

Nat Commun. 2024; 15: 3064. Published online 2024 Apr 9. doi: 10.1038/s41467-024-47173-z

PMCID:: PMC11004180

Abstract Article PDF–23M

Select item 108439825.

Chromogranin A regulates vesicle storage and mitochondrial dynamics to influence insulin secretion

Joshua Wollam, Sumana Mahata, Matthew Riopel, Angelina Hernandez-Carretero, Angshuman Biswas, Gautam K. Bandyopadhyay, Nai-Wen Chi, Lee E. Eiden, Nitish R. Mahapatra, Angelo Corti, Nicholas J. G. Webster, Sushil K. Mahata

Cell Tissue Res. Author manuscript; available in PMC 2024 Feb 5.

Published in final edited form as: Cell Tissue Res. 2017 Jun; 368(3): 487–501. Published online 2017 Feb 20. doi: 10.1007/s00441-017-2580-5

PMCID:: PMC10843982

Abstract Article PDF–3.5M

Select item 107582916.

Interleukin-33 facilitates liver regeneration through serotonin-involved gut-liver axis

Yankai Wen, Christoph Emontzpohl, Long Xu, Constance L. Atkins, Jong-Min Jeong, Yang Yang, Kangho Kim, Chuan Wu, Shizuo Akira, Cynthia Ju

Hepatology. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: Hepatology. 2023 May 1; 77(5): 1580–1592. Published online 2023 Apr 17. doi: 10.1002/hep.32744

PMCID:: PMC10758291

Abstract Article PDF–3.2M

Select item 105270427.

Lipids regulate peripheral serotonin release via gut CD1d

Jialie Luo, Zuojia Chen, David Castellano, Bin Bao, Wenyan Han, Jian Li, Girak Kim, Dingding An, Wei Lu, Chuan Wu

Immunity. Author manuscript; available in PMC 2024 Jul 11.

Published in final edited form as: Immunity. 2023 Jul 11; 56(7): 1533–1547.e7. Published online 2023 Jun 23. doi: 10.1016/j.immuni.2023.06.001

PMCID:: PMC10527042

Abstract Article PDF–2.6M

Select item 104824298.

Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation

Wilma Tixi, Maricela Maldonado, Ya-Ting Chang, Amy Chiu, Wilson Yeung, Nazia Parveen, Michael S Nelson, Ryan Hart, Shihao Wang, Wu Jih Hsu, Patrick Fueger, Janel L Kopp, Mark O Huising, Sangeeta Dhawan, Hung Ping Shih

eLife. 2023; 12: e90006. Published online 2023 Aug 23. doi: 10.7554/eLife.90006

PMCID:: PMC10482429

Abstract Article PDF–26M

Select item 103931939.

Major β cell-specific functions of NKX2.2 are mediated via the NK2-specific domain

Vladimir Abarinov, Joshua A. Levine, Angela J. Churchill, Bryce Hopwood, Cailin S. Deiter, Michelle A. Guney, Kristen L. Wells, Jessica M. Schrunk, Yuchun Guo, Jennifer Hammelman, David K. Gifford, Mark A. Magnuson, Hynek Wichterle, Lori Sussel

Genes Dev. 2023 Jun 1; 37(11-12): 490–504. doi: 10.1101/gad.350569.123

PMCID:: PMC10393193

Abstract Article PDF–22M

Select item 1025300210.

TCF7L1 Controls the Differentiation of Tuft Cells in Mouse Small Intestine

Valeriya V. Zinina, Melanie Sauer, Lira Nigmatullina, Nastasja Kreim, Natalia Soshnikova

Cells. 2023 Jun; 12(11): 1452. Published online 2023 May 23. doi: 10.3390/cells12111452

PMCID:: PMC10253002

Abstract Article PDF–2.4M

Select item 1014760411.

USP7 controls NGN3 stability and pancreatic endocrine lineage development

Teodora Manea, Jessica Kristine Nelson, Cristina Maria Garrone, Karin Hansson, Ian Evans, Axel Behrens, Rocio Sancho

Nat Commun. 2023; 14: 2457. Published online 2023 Apr 28. doi: 10.1038/s41467-023-38146-9

PMCID:: PMC10147604

Abstract Article PDF–9.0M

Select item 1013048712.

DNA Methylation–Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic β-Cell Heterogeneity

Nazia Parveen, Jean Kimi Wang, Supriyo Bhattacharya, Janielle Cuala, Mohan Singh Rajkumar, Alexandra E. Butler, Xiwei Wu, Hung-Ping Shih, Senta K. Georgia, Sangeeta Dhawan

Diabetes. 2023 May; 72(5): 575–589. Published online 2023 Jan 6. doi: 10.2337/db22-0506

Correction in:: Diabetes. 2023 Dec; 72(12): 1882.

PMCID:: PMC10130487

Abstract Article PDF–1.8M

Select item 1012146813.

Loss of Fgf9 in mice leads to pancreatic hypoplasia and asplenia

Sophie Patzek, Zhe Liu, Sean de la O, Sean Chang, Lauren E. Byrnes, Xiuqin Zhang, David M. Ornitz, Julie B. Sneddon

iScience. 2023 Apr 21; 26(4): 106500. Published online 2023 Mar 25. doi: 10.1016/j.isci.2023.106500

PMCID:: PMC10121468

Abstract Article PDF–12M

Select item 969165414.

Gut microbial DNA and immune checkpoint gene Vsig4/CRIg are key antagonistic players in healthy aging and age-associated development of hypertension and diabetes

Matthew A. Liu, Shandy Shahabi, Suborno Jati, Kechun Tang, Hong Gao, Zhongmou Jin, Wyatt Miller, Frédéric A. Meunier, Wei Ying, Geert van den Bogaart, Gourisankar Ghosh, Sushil K. Mahata

Front Endocrinol (Lausanne) 2022; 13: 1037465. Published online 2022 Nov 11. doi: 10.3389/fendo.2022.1037465

PMCID:: PMC9691654

Abstract Article PDF–19M

Select item 935276515.

Synaptotagmin-13 orchestrates pancreatic endocrine cell egression and islet morphogenesis

Mostafa Bakhti, Aimée Bastidas-Ponce, Sophie Tritschler, Oliver Czarnecki, Marta Tarquis-Medina, Eva Nedvedova, Jessica Jaki, Stefanie J. Willmann, Katharina Scheibner, Perla Cota, Ciro Salinno, Karsten Boldt, Nicola Horn, Marius Ueffing, Ingo Burtscher, Fabian J. Theis, Ünal Coskun, Heiko Lickert

Nat Commun. 2022; 13: 4540. Published online 2022 Aug 4. doi: 10.1038/s41467-022-31862-8

PMCID:: PMC9352765

Abstract Article PDF–15M

Select item 918147016.

Nrf2 Transcriptional Activity Governs Intestine Development

Aleksandra Kopacz, Damian Kloska, Dominika Klimczyk, Magdalena Kopec, Alicja Jozkowicz, Aleksandra Piechota-Polanczyk

Int J Mol Sci. 2022 Jun; 23(11): 6175. Published online 2022 May 31. doi: 10.3390/ijms23116175

PMCID:: PMC9181470

Abstract Article PDF–5.8M

Select item 911033317.

A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs

Yan Ting Shue, Alexandros P. Drainas, Nancy Yanzhe Li, Sarah M. Pearsall, Derrick Morgan, Nasa Sinnott-Armstrong, Susan Q. Hipkins, Garry L. Coles, Jing Shan Lim, Anthony E. Oro, Kathryn L. Simpson, Caroline Dive, Julien Sage

Nat Commun. 2022; 13: 2690. Published online 2022 May 16. doi: 10.1038/s41467-022-30416-2

PMCID:: PMC9110333

Abstract Article PDF–7.0M

Select item 910970818.

Chromogranin A pathway: From pathogenic molecule to renal disease

Saiful A. Mir, Nilima Biswas, Wai Cheung, Ji Wan, Nicholas Webster, Etienne Macedo, Daniel T. O’Connora, Sucheta M. Vaingankar

J Hypertens. Author manuscript; available in PMC 2022 May 16.

Published in final edited form as: J Hypertens. 2020 Mar; 38(3): 456–466. doi: 10.1097/HJH.0000000000002295

PMCID:: PMC9109708

Abstract Article PDF–2.5M

Select item 895218519.

Intestinal IL-33 promotes platelet activity for neutrophil recruitment during acute inflammation

Zuojia Chen, Jialie Luo, Jian Li, Girak Kim, Andy Stewart, Yuefeng Huang, Chuan Wu

Blood. 2022 Mar 24; 139(12): 1878–1891. doi: 10.1182/blood.2021013474

PMCID:: PMC8952185

Abstract Article

Select item 866098420.

Chromogranin A Deficiency Confers Protection From Autoimmune Diabetes via Multiple Mechanisms

Neetu Srivastava, Hao Hu, Anthony N. Vomund, Orion J. Peterson, Rocky L. Baker, Kathryn Haskins, Luc Teyton, Xiaoxiao Wan, Emil R. Unanue

Diabetes. 2021 Dec; 70(12): 2860–2870. Published online 2021 Sep 8. doi: 10.2337/db21-0513

PMCID:: PMC8660984

Abstract Article PDF–1.6M

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