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Items: 1 to 20 of 44

1.
Tropomodulin1 exacerbates inflammatory response in macrophages by negatively regulating LPS-induced TLR4 endocytosis
Xueyu Geng, Xue Xia, Zhenhui Liang, Shuo Li, Zejun Yue, Huan Zhang, Lina Guo, Shan Ma, Siyu Jiang, Xiang Lian, Jing Zhou, Lanping Amy Sung, Xifu Wang, Weijuan Yao
Cell Mol Life Sci. 2024 Dec; 81(1): 402. Published online 2024 Sep 14. doi: 10.1007/s00018-024-05424-8
PMCID:
PMC11401823
AbstractArticlePDF–3.7M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
4.
Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro
Tulsi Patel, Jennifer Hammelman, Siaresh Aziz, Sumin Jang, Michael Closser, Theodore L. Michaels, Jacob A. Blum, David K. Gifford, Hynek Wichterle
Nat Commun. 2022; 13: 5427. Published online 2022 Sep 15. doi: 10.1038/s41467-022-33022-4
PMCID:
PMC9477853
AbstractArticlePDF–7.4M
5.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
6.
Tropomodulin1 Expression Increases Upon Maturation in Dendritic Cells and Promotes Their Maturation and Immune Functions
Xianmei Liu, Xue Xia, Xifu Wang, Jing Zhou, Lanping Amy Sung, Jinhua Long, Xueyu Geng, Zhu Zeng, Weijuan Yao
Front Immunol. 2020; 11: 587441. Published online 2021 Jan 15. doi: 10.3389/fimmu.2020.587441
PMCID:
PMC7856346
AbstractArticlePDF–2.9M
7.
Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant
Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely
Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089
PMCID:
PMC7295033
AbstractArticlePDF–2.7M
8.
Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate
Rui Gao, Xingqun Liang, Sirisha Cheedipudi, Julio Cordero, Xue Jiang, Qingquan Zhang, Luca Caputo, Stefan Günther, Carsten Kuenne, Yonggang Ren, Shoumo Bhattacharya, Xuejun Yuan, Guillermo Barreto, Yihan Chen, Thomas Braun, Sylvia M. Evans, Yunfu Sun, Gergana Dobreva
Cell Res. 2019 Jun; 29(6): 486–501. Published online 2019 Apr 25. doi: 10.1038/s41422-019-0168-1
PMCID:
PMC6796926
AbstractArticlePDF–6.5M
9.
Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner
Paul R. Evans, Kyle J. Gerber, Eric B. Dammer, Duc M. Duong, Devrishi Goswami, Daniel J. Lustberg, Juan Zou, Jenny J. Yang, Serena M. Dudek, Patrick R. Griffin, Nicholas T. Seyfried, John R. Hepler
J Proteome Res. Author manuscript; available in PMC 2019 Jun 7.
Published in final edited form as: J Proteome Res. 2018 Apr 6; 17(4): 1700–1711. Published online 2018 Mar 20. doi: 10.1021/acs.jproteome.8b00027
PMCID:
PMC6554723
AbstractArticlePDF–2.0M
10.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
11.
The actin-organizing formin protein Fhod3 is required for postnatal development and functional maintenance of the adult heart in mice
Tomoki Ushijima, Noriko Fujimoto, Sho Matsuyama, Meikun Kan-o, Hiroshi Kiyonari, Go Shioi, Yohko Kage, Sho Yamasaki, Ryu Takeya, Hideki Sumimoto
J Biol Chem. 2018 Jan 5; 293(1): 148–162. Published online 2017 Nov 20. doi: 10.1074/jbc.M117.813931
PMCID:
PMC5766910
AbstractArticlePDF–4.5M
12.
HSPB7 is indispensable for heart development by modulating actin filament assembly
Tongbin Wu, Yongxin Mu, Julius Bogomolovas, Xi Fang, Jennifer Veevers, Roberta B. Nowak, Christopher T. Pappas, Carol C. Gregorio, Sylvia M. Evans, Velia M. Fowler, Ju Chen
Proc Natl Acad Sci U S A. 2017 Nov 7; 114(45): 11956–11961. Published online 2017 Oct 23. doi: 10.1073/pnas.1713763114
PMCID:
PMC5692592
AbstractArticlePDF–1.1M
13.
Tropomodulin 1 controls erythroblast enucleation via regulation of F-actin in the enucleosome
Roberta B. Nowak, Julien Papoin, David S. Gokhin, Carla Casu, Stefano Rivella, Jeffrey M. Lipton, Lionel Blanc, Velia M. Fowler
Blood. 2017 Aug 31; 130(9): 1144–1155. Prepublished online 2017 Jul 20. doi: 10.1182/blood-2017-05-787051
PMCID:
PMC5580276
AbstractArticle
14.
Circulating primitive erythroblasts establish a functional, protein 4.1R-dependent cytoskeletal network prior to enucleating
Yu-Shan Huang, Luis F. Delgadillo, Kathryn H. Cyr, Paul D. Kingsley, Xiuli An, Kathleen E. McGrath, Narla Mohandas, John G. Conboy, Richard E. Waugh, Jiandi Wan, James Palis
Sci Rep. 2017; 7: 5164. Published online 2017 Jul 12. doi: 10.1038/s41598-017-05498-4
PMCID:
PMC5507979
AbstractArticlePDF–2.1M
15.
Tropomodulin 1 Regulation of Actin Is Required for the Formation of Large Paddle Protrusions Between Mature Lens Fiber Cells
Catherine Cheng, Roberta B. Nowak, Sondip K. Biswas, Woo-Kuen Lo, Paul G. FitzGerald, Velia M. Fowler
Invest Ophthalmol Vis Sci. 2016 Aug; 57(10): 4084–4099. Published online 2016 Aug 8. doi: 10.1167/iovs.16-19949
PMCID:
PMC4986768
AbstractArticlePDF–3.1M
16.
Tropomodulin 1 directly controls thin filament length in both wild-type and tropomodulin 4-deficient skeletal muscle
David S. Gokhin, Julien Ochala, Andrea A. Domenighetti, Velia M. Fowler
Development. 2015 Dec 15; 142(24): 4351–4362. doi: 10.1242/dev.129171
PMCID:
PMC4689220
AbstractArticle
17.
Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality
Christopher T. Pappas, Rachel M. Mayfield, Christine Henderson, Nima Jamilpour, Cathleen Cover, Zachary Hernandez, Kirk R. Hutchinson, Miensheng Chu, Ki-Hwan Nam, Jose M. Valdez, Pak Kin Wong, Henk L. Granzier, Carol C. Gregorio
Proc Natl Acad Sci U S A. 2015 Nov 3; 112(44): 13573–13578. Published online 2015 Oct 20. doi: 10.1073/pnas.1508273112
PMCID:
PMC4640780
AbstractArticlePDF–1.2M
18.
How Leiomodin and Tropomodulin use a common fold for different actin assembly functions
Malgorzata Boczkowska, Grzegorz Rebowski, Elena Kremneva, Pekka Lappalainen, Roberto Dominguez
Nat Commun. 2015; 6: 8314. Published online 2015 Sep 15. doi: 10.1038/ncomms9314
PMCID:
PMC4571291
AbstractArticlePDF–4.1M
19.
Lens ion homeostasis relies on the assembly and/or stability of large connexin 46 gap junction plaques on the broad sides of differentiating fiber cells
Catherine Cheng, Roberta B. Nowak, Junyuan Gao, Xiurong Sun, Sondip K. Biswas, Woo-Kuen Lo, Richard T. Mathias, Velia M. Fowler
Am J Physiol Cell Physiol. 2015 May 15; 308(10): C835–C847. Published online 2015 Mar 4. doi: 10.1152/ajpcell.00372.2014
PMCID:
PMC4436989
AbstractArticle
20.
Tropomyosin is required for cardiac morphogenesis, myofibril assembly, and formation of adherens junctions in the developing mouse embryo
Caroline R. McKeown, Roberta B. Nowak, David S. Gokhin, Velia M. Fowler
Dev Dyn. Author manuscript; available in PMC 2015 Jun 1.
Published in final edited form as: Dev Dyn. 2014 Jun; 243(6): 800–817. Published online 2014 Feb 24. doi: 10.1002/dvdy.24115
PMCID:
PMC4031292
AbstractArticlePDF–3.9M

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