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Items: 1 to 20 of 34

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities
Chao Liu, Lingang Sun, Yijun Tan, Qi Wang, Tao Luo, Chenlu Li, Nan Yao, Yuting Xie, Xiao Yi, Yi Zhu, Tiannan Guo, Junfeng Ji
Sci Adv. 2023 May; 9(20): eade3888. Published online 2023 May 17. doi: 10.1126/sciadv.ade3888
PMCID:
PMC10191441
AbstractArticlePDF–2.4M
3.
SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination
Yongjuan Guan, Huijuan Lin, N Adrian Leu, Gordon Ruthel, Serge Y Fuchs, Luca Busino, Mengcheng Luo, P Jeremy Wang
Nucleic Acids Res. 2022 May 20; 50(9): 5129–5144. Published online 2022 Apr 30. doi: 10.1093/nar/gkac304
PMCID:
PMC9122608
AbstractArticlePDF–13M
4.
Single‐cell RNA‐Seq reveals a highly coordinated transcriptional program in mouse germ cells during primordial follicle formation
Yuanlin He, Qiuzhen Chen, Juncheng Dai, Yiqiang Cui, Chi Zhang, Xidong Wen, Jiazhao Li, Yue Xiao, Xiaoxu Peng, Mingxi Liu, Bin Shen, Jiahao Sha, Zhibin Hu, Jing Li, Wenjie Shu
Aging Cell. 2021 Jul; 20(7): e13424. Published online 2021 Jun 26. doi: 10.1111/acel.13424
PMCID:
PMC8282241
AbstractArticlePDF–3.6M
5.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
6.
Prdm9 and meiotic cohesin proteins cooperatively promote DNA double-strand break formation in mammalian spermatocytes
Tanmoy Bhattacharyya, Michael Walker, Natalie R Powers, Catherine Brunton, Alexander D Fine, Petko M Petkov, Mary Ann Handel
Curr Biol. Author manuscript; available in PMC 2020 Mar 18.
Published in final edited form as: Curr Biol. 2019 Mar 18; 29(6): 1002–1018.e7. Published online 2019 Mar 7. doi: 10.1016/j.cub.2019.02.007
Correction in:
Curr Biol. 2021 Mar 22; 31(6): 1351.
PMCID:
PMC6544150
AbstractArticlePDF–2.6M
7.
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program
John P. Sundberg, Soheil S. Dadras, Kathleen A. Silva, Victoria E. Kennedy, Gaven Garland, Stephen A. Murray, Beth A. Sundberg, Paul N. Schofield, C. Herbert Pratt
PLoS One. 2017; 12(7): e0180682. Published online 2017 Jul 10. doi: 10.1371/journal.pone.0180682
PMCID:
PMC5503261
AbstractArticlePDF–31M
8.
Sororin is enriched at the central region of synapsed meiotic chromosomes
Philip W. Jordan, Craig Eyster, Jingrong Chen, Roberto J. Pezza, Susannah Rankin
Chromosome Res. Author manuscript; available in PMC 2018 Jun 1.
Published in final edited form as: Chromosome Res. 2017 Jun; 25(2): 115–128. Published online 2017 Jan 3. doi: 10.1007/s10577-016-9542-8
PMCID:
PMC5441961
AbstractArticlePDF–2.1M
9.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
10.
C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility
Laura Gómez-H, Natalia Felipe-Medina, Manuel Sánchez-Martín, Owen R. Davies, Isabel Ramos, Ignacio García-Tuñón, Dirk G. de Rooij, Ihsan Dereli, Attila Tóth, José Luis Barbero, Ricardo Benavente, Elena Llano, Alberto M. Pendas
Nat Commun. 2016; 7: 13298. Published online 2016 Oct 31. doi: 10.1038/ncomms13298
PMCID:
PMC5095591
AbstractArticlePDF–4.9M
11.
Genetic Interactions Between the Meiosis-Specific Cohesin Components, STAG3, REC8, and RAD21L
Ayobami Ward, Jessica Hopkins, Matthew Mckay, Steve Murray, Philip W. Jordan
G3 (Bethesda) 2016 Jun; 6(6): 1713–1724. Published online 2016 Apr 16. doi: 10.1534/g3.116.029462
PMCID:
PMC4889667
AbstractArticlePDF–2.5M
12.
Meiotic cohesin STAG3 is required for chromosome axis formation and sister chromatid cohesion
Tristan Winters, Francois McNicoll, Rolf Jessberger
EMBO J. 2014 Jun 2; 33(11): 1256–1270. Published online 2014 May 5. doi: 10.1002/embj.201387330
PMCID:
PMC4198028
AbstractArticlePDF–5.7M
13.
STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis
Tomoyuki Fukuda, Nanaho Fukuda, Ana Agostinho, Abrahan Hernández-Hernández, Anna Kouznetsova, Christer Höög
EMBO J. 2014 Jun 2; 33(11): 1243–1255. Published online 2014 May 5. doi: 10.1002/embj.201387329
PMCID:
PMC4198027
AbstractArticlePDF–2.5M
14.
Meiosis-Specific Cohesin Component, Stag3 Is Essential for Maintaining Centromere Chromatid Cohesion, and Required for DNA Repair and Synapsis between Homologous Chromosomes
Jessica Hopkins, Grace Hwang, Justin Jacob, Nicklas Sapp, Rick Bedigian, Kazuhiro Oka, Paul Overbeek, Steve Murray, Philip W. Jordan
PLoS Genet. 2014 Jul; 10(7): e1004413. Published online 2014 Jul 3. doi: 10.1371/journal.pgen.1004413
PMCID:
PMC4081007
AbstractArticlePDF–17M
15.
Mutant Cohesin in Premature Ovarian Failure
Sandrine Caburet, Valerie A. Arboleda, Elena Llano, Paul A. Overbeek, Jose Luis Barbero, Kazuhiro Oka, Wilbur Harrison, Daniel Vaiman, Ziva Ben-Neriah, Ignacio García-Tuñón, Marc Fellous, Alberto M. Pendás, Reiner A. Veitia, Eric Vilain
N Engl J Med. Author manuscript; available in PMC 2014 Sep 6.
Published in final edited form as: N Engl J Med. 2014 Mar 6; 370(10): 943–949. doi: 10.1056/NEJMoa1309635
PMCID:
PMC4068824
AbstractArticlePDF–604K
16.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
17.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
18.
Meiotic cohesin complexes are essential for the formation of the axial element in mice
Elena Llano, Yurema Herrán, Ignacio García-Tuñón, Cristina Gutiérrez-Caballero, Enrique de Álava, José Luis Barbero, John Schimenti, Dirk G. de Rooij, Manuel Sánchez-Martín, Alberto M. Pendás
J Cell Biol. 2012 Jun 25; 197(7): 877–885. doi: 10.1083/jcb.201201100
PMCID:
PMC3384418
AbstractArticlePDF–2.4M
19.
Phosphorylation of Chromosome Core Components May Serve as Axis Marks for the Status of Chromosomal Events during Mammalian Meiosis
Tomoyuki Fukuda, Florencia Pratto, John C. Schimenti, James M. A. Turner, R. Daniel Camerini-Otero, Christer Höög
PLoS Genet. 2012 Feb; 8(2): e1002485. Published online 2012 Feb 9. doi: 10.1371/journal.pgen.1002485
PMCID:
PMC3276554
AbstractArticlePDF–1.0M
20.
Meiosis in Mice without a Synaptonemal Complex
Anna Kouznetsova, Ricardo Benavente, Albert Pastink, Christer Höög
PLoS One. 2011; 6(12): e28255. Published online 2011 Dec 2. doi: 10.1371/journal.pone.0028255
PMCID:
PMC3229524
AbstractArticlePDF–3.4M

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