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Select item 111962081.

IGFBP7 promotes endothelial cell repair in the recovery phase of acute lung injury

Rui He, Bo Feng, Yuezhou Zhang, Yuqing Li, Daoxing Wang, Linchao Yu

Clin Sci (Lond) 2024 Jul; 138(13): 797–815. Published online 2024 Jun 21. doi: 10.1042/CS20240179

PMCID:: PMC11196208

Abstract Article PDF–10M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 101914413.

USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities

Chao Liu, Lingang Sun, Yijun Tan, Qi Wang, Tao Luo, Chenlu Li, Nan Yao, Yuting Xie, Xiao Yi, Yi Zhu, Tiannan Guo, Junfeng Ji

Sci Adv. 2023 May; 9(20): eade3888. Published online 2023 May 17. doi: 10.1126/sciadv.ade3888

PMCID:: PMC10191441

Abstract Article PDF–2.4M

Select item 96755564.

DIO3 protects against thyrotoxicosis-derived cranio-encephalic and cardiac congenital abnormalities

M. Elena Martinez, Ilka Pinz, Marilena Preda, Christine R. Norton, Thomas Gridley, Arturo Hernandez

JCI Insight. 2022 Nov 8; 7(21): e161214. Published online 2022 Nov 8. doi: 10.1172/jci.insight.161214

PMCID:: PMC9675556

Abstract Article PDF–3.9M

Select item 78230765.

Genetic association and characterization of FSTL5 in isolated clubfoot

Anas M Khanshour, Yared H Kidane, Julia Kozlitina, Reuel Cornelia, Alexandra Rafipay, Vanessa De Mello, Mitchell Weston, Nandina Paria, Aysha Khalid, Jacqueline T Hecht, Matthew B Dobbs, B Stephens Richards, Neil Vargesson, F Kent Hamra, Megan Wilson, Carol Wise, Christina A Gurnett, Jonathan J Rios

Hum Mol Genet. 2020 Nov 15; 29(22): 3717–3728. Published online 2020 Oct 26. doi: 10.1093/hmg/ddaa236

PMCID:: PMC7823076

Abstract Article PDF–1.0M

Select item 71108276.

Angiomodulin (IGFBP7) is a cerebral specific angiocrine factor, but is probably not a blood–brain barrier inducer

Ofri Bar, Sivan Gelb, Kian Atamny, Shira Anzi, Ayal Ben-Zvi

Fluids Barriers CNS. 2020; 17: 27. Published online 2020 Apr 1. doi: 10.1186/s12987-020-00188-2

PMCID:: PMC7110827

Abstract Article PDF–1.6M

Select item 70463087.

IGFBP7 acts as a negative regulator of RANKL‐induced osteoclastogenesis and oestrogen deficiency‐induced bone loss

Chenyi Ye, Weiduo Hou, Mo Chen, Jinwei Lu, Erman Chen, Lan Tang, Kai Hang, Qianhai Ding, Yan Li, Wei Zhang, Rongxin He

Cell Prolif. 2020 Feb; 53(2): e12752. Published online 2019 Dec 30. doi: 10.1111/cpr.12752

PMCID:: PMC7046308

Abstract Article PDF–2.7M

Select item 69833578.

MS/MS in silico subtraction-based proteomic profiling as an approach to facilitate disease gene discovery: application to lens development and cataract

Sandeep Aryal, Deepti Anand, Francisco G. Hernandez, Bailey A. T. Weatherbee, Hongzhan Huang, Ashok P. Reddy, Phillip A. Wilmarth, Larry L. David, Salil A. Lachke

Hum Genet. Author manuscript; available in PMC 2021 Feb 1.

Published in final edited form as: Hum Genet. 2020 Feb; 139(2): 151–184. Published online 2019 Dec 3. doi: 10.1007/s00439-019-02095-5

PMCID:: PMC6983357

Abstract Article PDF–3.8M

Select item 69109269.

Molecular determinants of nephron vascular specialization in the kidney

David M. Barry, Elizabeth A. McMillan, Balvir Kunar, Raphael Lis, Tuo Zhang, Tyler Lu, Edward Daniel, Masataka Yokoyama, Jesus M. Gomez-Salinero, Angara Sureshbabu, Ondine Cleaver, Annarita Di Lorenzo, Mary E. Choi, Jenny Xiang, David Redmond, Sina Y. Rabbany, Thangamani Muthukumar, Shahin Rafii

Nat Commun. 2019; 10: 5705. Published online 2019 Dec 13. doi: 10.1038/s41467-019-12872-5

PMCID:: PMC6910926

Abstract Article PDF–6.4M

Select item 686471310.

Eleutheroside B Protects against Acute Kidney Injury by Activating IGF Pathway

Hongmei Zang, Qin Yang, Jun Li

Molecules. 2019 Nov; 24(21): 3876. Published online 2019 Oct 28. doi: 10.3390/molecules24213876

PMCID:: PMC6864713

Abstract Article PDF–3.9M

Select item 632983111.

Single-cell transcriptomic analysis of mouse neocortical development

Lipin Loo, Jeremy M. Simon, Lei Xing, Eric S. McCoy, Jesse K. Niehaus, Jiami Guo, E. S. Anton, Mark J. Zylka

Nat Commun. 2019; 10: 134. Published online 2019 Jan 11. doi: 10.1038/s41467-018-08079-9

PMCID:: PMC6329831

Abstract Article PDF–3.6M

Select item 619212112.

Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis

Takae Kiyama, Ching-Kang Chen, Steven W Wang, Ping Pan, Zhenlin Ju, Jing Wang, Shinako Takada, William H Klein, Chai-An Mao

Mol Neurodegener. 2018; 13: 56. Published online 2018 Oct 17. doi: 10.1186/s13024-018-0287-z

PMCID:: PMC6192121

Abstract Article PDF–12M

Select item 589428013.

IGFBP7 Deletion Promotes Hepatocellular Carcinoma

Maaged Akiel, Chunqing Guo, Xia Li, Devaraja Rajasekaran, Rachel G. Mendoza, Chadia L. Robertson, Nidhi Jariwala, Fang Yuan, Mark A. Subler, Jolene Windle, Dawn K. Garcia, Zhao Lai, Hung-I Harry Chen, Yidong Chen, Shah Giashuddin, Paul B. Fisher, Xiang-Yang Wang, Devanand Sarkar

Cancer Res. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Cancer Res. 2017 Aug 1; 77(15): 4014–4025. Published online 2017 Jun 15. doi: 10.1158/0008-5472.CAN-16-2885

PMCID:: PMC5894280

Abstract Article PDF–2.9M

Select item 576500514.

Lack of Fgf18 causes abnormal clustering of motor nerve terminals at the neuromuscular junction with reduced acetylcholine receptor clusters

Kenyu Ito, Bisei Ohkawara, Hideki Yagi, Hiroaki Nakashima, Mikito Tsushima, Kyotaro Ota, Hiroyuki Konishi, Akio Masuda, Shiro Imagama, Hiroshi Kiyama, Naoki Ishiguro, Kinji Ohno

Sci Rep. 2018; 8: 434. Published online 2018 Jan 11. doi: 10.1038/s41598-017-18753-5

PMCID:: PMC5765005

Abstract Article PDF–7.5M

Select item 549749515.

Molecular checkpoint decisions made by subverted vascular niche transform indolent tumor cells into chemoresistant cancer stem cells

Zhongwei Cao, Joseph M Scandura, Giorgio G. Inghirami, Koji Shido, Bi-Sen Ding, Shahin Rafii

Cancer Cell. Author manuscript; available in PMC 2017 Jul 5.

Published in final edited form as: Cancer Cell. 2017 Jan 9; 31(1): 110–126. Published online 2016 Dec 15. doi: 10.1016/j.ccell.2016.11.010

PMCID:: PMC5497495

Abstract Article PDF–5.0M

Select item 529582116.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356