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Select item 111593631.

Frequent alterations of the candidate genes hMLH1, ITGA9 and RBSP3 in early dysplastic lesions of head and neck: Clinical and prognostic significance

Amlan Ghosh, Susmita Ghosh, Guru Prasad Maiti, Mohammad Golam Sabbir, Eugene R. Zabarovsky, Anup Roy, Susanta Roychoudhury, Chinmay Kumar Panda

Cancer Sci. 2010 Jun; 101(6): 1511–1520. Published online 2010 Mar 4. doi: 10.1111/j.1349-7006.2010.01551.x

PMCID:: PMC11159363

Abstract Article PDF–891K

Select item 98051292.

The integrin ligand SVEP1 regulates GPCR‐mediated vasoconstriction via integrins α9β1 and α4β1

Gavin E. Morris, Matthew J. Denniff, Elisavet Karamanavi, Sarah A. Andrews, Renata B. Kostogrys, Vasiliki Bountziouka, Maryam Ghaderi‐Najafabadi, Noor Shamkhi, George McConnell, Michael A. Kaiser, Laura Carleton, Christine Schofield, Thorsten Kessler, Richard D. Rainbow, Nilesh J. Samani, Thomas R. Webb

Br J Pharmacol. 2022 Nov; 179(21): 4958–4973. Published online 2022 Aug 2. doi: 10.1111/bph.15921

PMCID:: PMC9805129

Abstract Article PDF–28M

Select item 95538333.

Integrin alpha9 emerges as a key therapeutic target to reduce metastasis in rhabdomyosarcoma and neuroblastoma

Natalia Navarro, Carla Molist, Júlia Sansa-Girona, Patricia Zarzosa, Gabriel Gallo-Oller, Guillem Pons, Ainara Magdaleno, Gabriela Guillén, Raquel Hladun, Marta Garrido, Miguel F. Segura, Lourdes Hontecillas-Prieto, Enrique de Álava, Berta Ponsati, Jimena Fernández-Carneado, Ana Almazán-Moga, Mariona Vallès-Miret, Josep Farrera-Sinfreu, Josep Sánchez de Toledo, Lucas Moreno, Soledad Gallego, Josep Roma

Cell Mol Life Sci. 2022; 79(11): 546. Published online 2022 Oct 11. doi: 10.1007/s00018-022-04557-y

PMCID:: PMC9553833

Abstract Article PDF–2.5M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80919285.

Tenascin-C and integrin α9 mediate interactions of prostate cancer with the bone microenvironment

Rebeca San Martin, Ravi Pathak, Antrix Jain, Sung Yun Jung, Susan G. Hilsenbeck, María C. Piña-Barba, Andrew G. Sikora, Kenneth J. Pienta, David R. Rowley

Cancer Res. Author manuscript; available in PMC 2021 May 3.

Published in final edited form as: Cancer Res. 2017 Nov 1; 77(21): 5977–5988. Published online 2017 Sep 15. doi: 10.1158/0008-5472.CAN-17-0064

PMCID:: PMC8091928

Abstract Article PDF–2.3M

Select item 67814306.

Perlecan regulates pericyte dynamics in the maintenance and repair of the blood–brain barrier

Kuniyuki Nakamura, Tomoko Ikeuchi, Kazuki Nara, Craig S. Rhodes, Peipei Zhang, Yuta Chiba, Saiko Kazuno, Yoshiki Miura, Tetsuro Ago, Eri Arikawa-Hirasawa, Yoh-suke Mukouyama, Yoshihiko Yamada

J Cell Biol. 2019 Oct 7; 218(10): 3506–3525. Published online 2019 Sep 20. doi: 10.1083/jcb.201807178

PMCID:: PMC6781430

Abstract Article PDF–5.3M

Select item 67509617.

Integrin α9 depletion promotes β-catenin degradation to suppress triple negative breast cancer tumor growth and metastasis

Zhishan Wang, Yunfei Li, Yajuan Xiao, Hsuan-Pei Lin, Ping Yang, Brock Humphries, Tianyan Gao, Chengfeng Yang

Int J Cancer. Author manuscript; available in PMC 2020 Nov 15.

Published in final edited form as: Int J Cancer. 2019 Nov 15; 145(10): 2767–2780. Published online 2019 May 3. doi: 10.1002/ijc.32359

PMCID:: PMC6750961

Abstract Article PDF–1.2M

Select item 66658498.

α9 Integrin Promotes Neurite Outgrowth on Tenascin-C and Enhances Sensory Axon Regeneration

Melissa R. Andrews, Stefan Czvitkovich, Elisa Dassie, Christina F. Vogelaar, Andreas Faissner, Bas Blits, Fred H. Gage, Charles ffrench-Constant, James W. Fawcett

J Neurosci. 2009 Apr 29; 29(17): 5546–5557. doi: 10.1523/JNEUROSCI.0759-09.2009

PMCID:: PMC6665849

Abstract Article PDF–11M

Select item 59892809.

Integrin α9 Suppresses Hepatocellular Carcinoma Metastasis by Rho GTPase Signaling

Yan-Li Zhang, Xin Xing, Li-Bo Cai, Lei Zhu, Xiao-Mei Yang, Ya-Hui Wang, Qin Yang, Hui-Zhen Nie, Zhi-Gang Zhang, Jun Li, Xue-Li Zhang

J Immunol Res. 2018; 2018: 4602570. Published online 2018 May 24. doi: 10.1155/2018/4602570

PMCID:: PMC5989280

Abstract Article PDF–7.4M

Select item 567281810.

Constitutive Activation of Integrin α9 Augments Self-Directed Hyperplastic and Proinflammatory Properties of Fibroblast-like Synoviocytes of Rheumatoid Arthritis

Takashi Emori, Jun Hirose, Kotoko Ise, Jun-ichiro Yomoda, Michiko Kasahara, Tadanobu Shinkuma, Hiroyuki Yoshitomi, Hiromu Ito, Motomu Hashimoto, Shingo Sugahara, Hirotada Fujita, Nobuchika Yamamoto, Yoshiaki Morita, Shuh Narumiya, Ichiro Aramori

J Immunol. 2017 Nov 15; 199(10): 3427–3436. Published online 2017 Oct 16. doi: 10.4049/jimmunol.1700941

PMCID:: PMC5672818

Abstract Article PDF–1.0M

Select item 553161111.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 541255512.

Suppression of integrin α3β1 by α9β1 in the epidermis controls the paracrine resolution of wound angiogenesis

Whitney M. Longmate, Scott P. Lyons, Sridar V. Chittur, Kevin M. Pumiglia, Livingston Van De Water, C. Michael DiPersio

J Cell Biol. 2017 May 1; 216(5): 1473–1488. doi: 10.1083/jcb.201510042

PMCID:: PMC5412555

Abstract Article PDF–2.2M

Select item 491015013.

F-box only protein 9 is an E3 ubiquitin ligase of PPARγ

Kyeong Won Lee, Soo Heon Kwak, Young Do Koo, Yun-Kyung Cho, Hak Mo Lee, Hye Seung Jung, Young Min Cho, Young Joo Park, Sung Soo Chung, Kyong Soo Park

Exp Mol Med. 2016 May; 48(5): e234. Published online 2016 May 20. doi: 10.1038/emm.2016.31

PMCID:: PMC4910150

Abstract Article PDF–1.1M

Select item 474162014.

Integrin α9 gene promoter is hypermethylated and downregulated in nasopharyngeal carcinoma

Imran Nawaz, Li-Fu Hu, Zi-Ming Du, Khalid Moumad, Ilya Ignatyev, Tatiana V. Pavlova, Vladimir Kashuba, Malin Almgren, Eugene R. Zabarovsky, Ingemar Ernberg

Oncotarget. 2015 Oct 13; 6(31): 31493–31507. Published online 2015 Sep 8. doi: 10.18632/oncotarget.5154

PMCID:: PMC4741620

Abstract Article PDF–3.2M

Select item 440901115.

Association of p75^NTR and α9β1 integrin modulates NGF-dependent cellular responses

Erin M. Ventresca, Shimon Lecht, Piotr Jakubowski, Rachel A. Chiaverelli, Michael Weaver, Luis Del Valle, Keren Ettinger, Galit Gincberg, Avi Priel, Alex Braiman, Philip Lazarovici, Peter I. Lelkes, Cezary Marcinkiewicz

Cell Signal. Author manuscript; available in PMC 2016 Jun 1.

Published in final edited form as: Cell Signal. 2015 Jun; 27(6): 1225–1236. Published online 2015 Mar 5. doi: 10.1016/j.cellsig.2015.02.029

PMCID:: PMC4409011

Abstract Article PDF–2.5M

Select item 388634116.

A Genome-Wide Association Study of Behavioral Disinhibition

Matt McGue, Yiwei Zhang, Michael B. Miller, Saonli Basu, Scott Vrieze, Brian Hicks, Steve Malone, William S. Oetting, William G. Iacono

Behav Genet. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: Behav Genet. 2013 Sep; 43(5): 10.1007/s10519-013-9606-x. Published online 2013 Aug 14. doi: 10.1007/s10519-013-9606-x

PMCID:: PMC3886341

Abstract Article PDF–175K

Select item 356036517.

Novel Loci Associated with PR Interval in a Genome-Wide Association Study of Ten African American Cohorts

Anne M. Butler, Xiaoyan Yin, Daniel S. Evans, Michael A. Nalls, Erin N. Smith, Toshiko Tanaka, Guo Li, Sarah G. Buxbaum, Eric A. Whitsel, Alvaro Alonso, Dan E. Arking, Emelia J. Benjamin, Gerald S. Berenson, Josh C. Bis, Wei Chen, Rajat Deo, Patrick T. Ellinor, Susan R. Heckbert, Gerardo Heiss, Wen-Chi Hsueh, Brendan J. Keating, Kathleen F. Kerr, Yun Li, Marian C. Limacher, Yongmei Liu, Steven A. Lubitz, Kristin D. Marciante, Reena Mehra, Yan A. Meng, Anne B. Newman, Christopher Newton-Cheh, Kari E. North, Cameron D. Palmer, Bruce M. Psaty, P. Miguel Quibrera, Susan Redline, Alex P. Reiner, Jerome I. Rotter, Renate B. Schnabel, Nicholas J. Schork, Andrew B. Singleton, J. Gustav Smith, Elsayed Z. Soliman, Sathanur R. Srinivasan, Zhu-ming Zhang, Alan B. Zonderman, Luigi Ferrucci, Sarah S. Murray, Michele K. Evans, Nona Sotoodehnia, Jared W. Magnani, Christy L. Avery

Circ Cardiovasc Genet. Author manuscript; available in PMC 2013 Dec 1.

Published in final edited form as: Circ Cardiovasc Genet. 2012 Dec 1; 5(6): 639–646. Published online 2012 Nov 8. doi: 10.1161/CIRCGENETICS.112.963991

PMCID:: PMC3560365

Abstract Article PDF–1.3M

Select item 349442818.

Notch-mediated induction of N-cadherin and α9-integrin confers higher invasive phenotype on rhabdomyosarcoma cells

A Masià, A Almazán-Moga, P Velasco, J Reventós, N Torán, J Sánchez de Toledo, J Roma, S Gallego

Br J Cancer. 2012 Oct 9; 107(8): 1374–1383. Published online 2012 Sep 13. doi: 10.1038/bjc.2012.411

PMCID:: PMC3494428

Abstract Article PDF–1.9M

Select item 336898919.

Integrin a9ß1 promotes malignant tumor growth and metastasis by potentiating epithelial-mesenchymal transition

Shiv K Gupta, Saji Oommen, Marie-Christine Aubry, Brian P. Williams, Nicholas E Vlahakis

Oncogene. Author manuscript; available in PMC 2013 Jul 10.

Published in final edited form as: Oncogene. 2013 Jan 10; 32(2): 141–150. Published online 2012 Feb 27. doi: 10.1038/onc.2012.41

PMCID:: PMC3368989

Abstract Article PDF–1.5M

Select item 333583120.

Co-Expression of α9β1 Integrin and VEGF-D Confers Lymphatic Metastatic Ability to a Human Breast Cancer Cell Line MDA-MB-468LN

Mousumi Majumder, Elena Tutunea-Fatan, Xiping Xin, Mauricio Rodriguez-Torres, Jose Torres-Garcia, Ryan Wiebe, Alexander V. Timoshenko, Rabindra N. Bhattacharjee, Ann F. Chambers, Peeyush K. Lala

PLoS One. 2012; 7(4): e35094. Published online 2012 Apr 24. doi: 10.1371/journal.pone.0035094

PMCID:: PMC3335831

Abstract Article PDF–2.4M

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