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Select item 112510821.

Early-stage lung cancer is driven by a transitional cell state dependent on a KRAS-ITGA3-SRC axis

Aaron L Moye, Antonella FM Dost, Robert Ietswaart, Shreoshi Sengupta, VanNashlee Ya, Chrystal Aluya, Caroline G Fahey, Sharon M Louie, Margherita Paschini, Carla F Kim

EMBO J. 2024 Jul; 43(14): 2843–2861. Published online 2024 May 16. doi: 10.1038/s44318-024-00113-5

PMCID:: PMC11251082

Abstract Article PDF–4.3M

Select item 111908632.

GRP78-c-Src信号通路介导周期性牵张力作用下牙周膜成纤维细胞成骨分化的机制研究

胡静, 崔智华, 黄克强, 苏荣健, 赵颂

Hua Xi Kou Qiang Yi Xue Za Zhi. 2024 Jun; 42(3): 304–312. Chinese. doi: 10.7518/hxkq.2024.2023354

PMCID:: PMC11190863

Abstract Article PDF–3.4M

Select item 111596383.

TUSC4/NPRL2, a novel PDK1‐interacting protein, inhibits PDK1 tyrosine phosphorylation and its downstream signaling

Atsuo Kurata, Ryohei Katayama, Toshiki Watanabe, Takashi Tsuruo, Naoya Fujita

Cancer Sci. 2008 Sep; 99(9): 1827–1834. Published online 2008 Jul 4. doi: 10.1111/j.1349-7006.2008.00874.x

PMCID:: PMC11159638

Abstract Article PDF–402K

Select item 111451364.

FAXC interacts with ANXA2 and SRC in mitochondria and promotes tumorigenesis in cholangiocarcinoma

Haruna Fujimori, Mao Shima‐Nakamura, Shin‐Ichiro Kanno, Rie Shibuya‐Takahashi, Mai Mochizuki, Masamichi Mizuma, Michiaki Unno, Yuta Wakui, Makoto Abue, Wataru Iwai, Daisuke Fukushi, Kennich Satoh, Kazunori Yamaguchi, Norihisa Shindo, Jun Yasuda, Keiichi Tamai

Cancer Sci. 2024 Jun; 115(6): 1896–1909. Published online 2024 Mar 13. doi: 10.1111/cas.16140

PMCID:: PMC11145136

Abstract Article PDF–7.8M

Select item 111317505.

Molecular mechanism underlying the association of Coronin-7 with Golgi membranes

V. Rybakin, R. H. Rastetter, M. Stumpf, A. C. Uetrecht, J. E. Bear, A. A. Noegel, C. S. Clemen

Cell Mol Life Sci. 2008 Aug; 65(15): 2419–2430. Published online 2008 Jun 26. doi: 10.1007/s00018-008-8278-9

PMCID:: PMC11131750

Abstract Article PDF–2.4M

Select item 111314956.

Src activation and translocation from focal adhesions to membrane ruffles contribute to formation of new adhesion sites

A. Hamadi, T. B. Deramaudt, K. Takeda, P. Rondé

Cell Mol Life Sci. 2009 Jan; 66(2): 324–338. Published online 2008 Dec 10. doi: 10.1007/s00018-008-8424-4

PMCID:: PMC11131495

Abstract Article PDF–4.9M

Select item 111145587.

CD24 controls Src/STAT3 activity in human tumors

Niko P. Bretz, Alexei V. Salnikov, Claudia Perne, Sascha Keller, Xiaoli Wang, Claudia T. Mierke, Mina Fogel, Natalie Erbe-Hofmann, Thomas Schlange, Gerhard Moldenhauer, Peter Altevogt

Cell Mol Life Sci. 2012 Nov; 69(22): 3863–3879. Published online 2012 Jul 4. doi: 10.1007/s00018-012-1055-9

PMCID:: PMC11114558

Abstract Article PDF–1.0M

Select item 111145368.

CD24 interacts with and promotes the activity of c-src within lipid rafts in breast cancer cells, thereby increasing integrin-dependent adhesion

Petra Baumann, Wilko Thiele, Natascha Cremers, Santoshi Muppala, Justyna Krachulec, Markus Diefenbacher, Olivier Kassel, Giridhar Mudduluru, Heike Allgayer, Margaret Frame, Jonathan P. Sleeman

Cell Mol Life Sci. 2012 Feb; 69(3): 435–448. Published online 2011 Jun 28. doi: 10.1007/s00018-011-0756-9

PMCID:: PMC11114536

Abstract Article PDF–731K

Select item 109168669.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 1086030110.

Superbinder based phosphoproteomic landscape revealed PRKCD_pY313 mediates the activation of Src and p38 MAPK to promote TNBC progression

Yujiao Deng, Zhanwu Hou, Yizhen Li, Ming Yi, Ying Wu, Yi Zheng, Fei Yang, Guansheng Zhong, Qian Hao, Zhen Zhai, Meng Wang, Xiaobin Ma, Huafeng Kang, Fanpu Ji, Chenfang Dong, Huadong Liu, Zhijun Dai

Cell Commun Signal. 2024; 22: 115. Published online 2024 Feb 12. doi: 10.1186/s12964-024-01487-z

PMCID:: PMC10860301

Abstract Article PDF–13M

Select item 1084976611.

TIMP2 ameliorates blood-brain barrier disruption in traumatic brain injury by inhibiting Src-dependent VE-cadherin internalization

Jingshu Tang, Yuying Kang, Yujun Zhou, Nianying Shang, Xinnan Li, Hongyue Wang, Jiaqi Lan, Shuai Wang, Lei Wu, Ying Peng

J Clin Invest. 2024 Feb 1; 134(3): e164199. Published online 2024 Feb 1. doi: 10.1172/JCI164199

PMCID:: PMC10849766

Abstract Article PDF–22M

Select item 1080373112.

Compartment-specific multiomic profiling identifies SRC and GNAS as candidate drivers of epithelial-to-mesenchymal transition in ovarian carcinosarcoma

C. Simon Herrington, Ailsa J. Oswald, Lorna J. Stillie, Ian Croy, Michael Churchman, Robert L. Hollis

Br J Cancer. 2024 Feb 10; 130(2): 327–335. Published online 2023 Dec 14. doi: 10.1038/s41416-023-02508-3

PMCID:: PMC10803731

Abstract Article PDF–2.4M

Select item 1071122313.

c-Src regulates δ-secretase activation and truncated Tau production by phosphorylating the E3 ligase Traf6

Yanli Jiang, Longfei Li, Ruozhen Wu, Liulin Wu, Bin Zhang, Jian-Zhi Wang, Rong Liu, Fei Liu, Jing Wang, Xiaochuan Wang

J Biol Chem. 2023 Dec; 299(12): 105462. Published online 2023 Nov 15. doi: 10.1016/j.jbc.2023.105462

PMCID:: PMC10711223

Abstract Article PDF–2.9M

Select item 1058217214.

An allosteric switch between the activation loop and a c-terminal palindromic phospho-motif controls c-Src function

Hipólito Nicolás Cuesta-Hernández, Julia Contreras, Pablo Soriano-Maldonado, Jana Sánchez-Wandelmer, Wayland Yeung, Ana Martín-Hurtado, Inés G. Muñoz, Natarajan Kannan, Marta Llimargas, Javier Muñoz, Iván Plaza-Menacho

Nat Commun. 2023; 14: 6548. Published online 2023 Oct 17. doi: 10.1038/s41467-023-41890-7

PMCID:: PMC10582172

Abstract Article PDF–5.0M

Select item 1046079415.

Identification and functional validation of SRC and RAPGEF1 as new direct targets of miR-203, involved in regulation of epidermal homeostasis

Christelle Golebiewski, Cécile Gastaldi, Diane-Lore Vieu, Bernard Mari, Roger Rezzonico, Françoise Bernerd, Claire Marionnet

Sci Rep. 2023; 13: 14006. Published online 2023 Aug 27. doi: 10.1038/s41598-023-40441-w

PMCID:: PMC10460794

Abstract Article PDF–4.4M

Select item 1044753316.

The activated CD36-Src axis promotes lung adenocarcinoma cell proliferation and actin remodeling-involved metastasis in high-fat environment

Li-Zhong Liu, Bowen Wang, Rui Zhang, Zangshu Wu, Yuxi Huang, Xiaoyang Zhang, Jiaying Zhou, Junbo Yi, Jian Shen, Ming-Yue Li, Ming Dong

Cell Death Dis. 2023 Aug; 14(8): 548. Published online 2023 Aug 23. doi: 10.1038/s41419-023-06078-3

PMCID:: PMC10447533

Abstract Article PDF–11M

Select item 1040358217.

SQLE promotes pancreatic cancer growth by attenuating ER stress and activating lipid rafts-regulated Src/PI3K/Akt signaling pathway

Ruiyuan Xu, Jianlu Song, Rexiati Ruze, Yuan Chen, Xinpeng Yin, Chengcheng Wang, Yupei Zhao

Cell Death Dis. 2023 Aug; 14(8): 497. Published online 2023 Aug 4. doi: 10.1038/s41419-023-05987-7

PMCID:: PMC10403582

Abstract Article PDF–8.1M

Select item 1036925718.

The c‐Src/LIST Positive Feedback Loop Sustains Tumor Progression and Chemoresistance

Xianteng Wang, Bing Wang, Fang Li, Xingkai Li, Ting Guo, Yushun Gao, Dawei Wang, Weiren Huang

Adv Sci (Weinh) 2023 Jul; 10(20): 2300115. Published online 2023 May 8. doi: 10.1002/advs.202300115

Correction in:: Adv Sci (Weinh). 2023 Dec; 10(36): 2307933.

PMCID:: PMC10369257

Abstract Article PDF–5.8M

Select item 1017419119.

The Src–ZNRF1 axis controls TLR3 trafficking and interferon responses to limit lung barrier damage

You-Sheng Lin, Yung-Chi Chang, Tai-Ling Chao, Ya-Min Tsai, Shu-Jhen Jhuang, Yu-Hsin Ho, Ting-Yu Lai, Yi-Ling Liu, Chiung-Ya Chen, Ching-Yen Tsai, Yi-Ping Hsueh, Sui-Yuan Chang, Tsung-Hsien Chuang, Chih-Yuan Lee, Li-Chung Hsu

J Exp Med. 2023 Aug 7; 220(8): e20220727. Published online 2023 May 9. doi: 10.1084/jem.20220727