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Items: 1 to 20 of 38

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Targeting the Mitochondrial Chaperone TRAP1 Alleviates Vascular Pathologies in Ischemic Retinopathy
So‐Yeon Kim, Nam Gu Yoon, Jin Young Im, Ji Hye Lee, Juhee Kim, Yujin Jeon, Young Jae Choi, Jong‐Hwa Lee, Akiyoshi Uemura, Dong Ho Park, Byoung Heon Kang
Adv Sci (Weinh) 2024 Jan; 11(2): 2302776. Published online 2023 Nov 20. doi: 10.1002/advs.202302776
PMCID:
PMC10787068
AbstractArticlePDF–18M
3.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
4.
The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins
Mickaële Hémono, Alexandre Haller, Johana Chicher, Anne-Marie Duchêne, Richard Patryk Ngondo
BMC Biol. 2022; 20: 13. Published online 2022 Jan 10. doi: 10.1186/s12915-021-01213-y
PMCID:
PMC8744257
AbstractArticlePDF–6.0M
5.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
6.
The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis
Shalini Menon, Dennis Goldfarb, Chris T. Ho, Erica W. Cloer, Nicholas P. Boyer, Christopher Hardie, Andrew J. Bock, Emma C. Johnson, Joel Anil, M. Ben Major, Stephanie L. Gupton
Mol Biol Cell. 2021 Feb 15; 32(4): 314–330. doi: 10.1091/mbc.E20-10-0622
PMCID:
PMC8098814
AbstractArticlePDF–7.7M
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
8.
ETAR and protein kinase A pathway mediate ET-1 sensitization of TRPA1 channel: A molecular mechanism of ET-1-induced mechanical hyperalgesia
Xiaoli Zheng, Yan Tai, Dongwei He, Boyu Liu, Chuan Wang, Xiaomei Shao, Sven-Eric Jordt, Boyi Liu
Mol Pain. 2019; 15: 1744806919842473. Published online 2019 May 20. doi: 10.1177/1744806919842473
PMCID:
PMC6537062
AbstractArticlePDF–952K
9.
ATG5 is required for B cell polarization and presentation of particulate antigens
Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros
Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327
PMCID:
PMC6333460
AbstractArticlePDF–2.7M
10.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
11.
Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells
Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch
Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262
PMCID:
PMC6244183
AbstractArticlePDF–753K
12.
A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies
David K. Breslow, Sascha Hoogendoorn, Adam R. Kopp, David W. Morgens, Brandon K. Vu, Margaret C. Kennedy, Kyuho Han, Amy Li, Gaelen T. Hess, Michael C. Bassik, James K. Chen, Maxence V. Nachury
Nat Genet. Author manuscript; available in PMC 2018 Aug 19.
Published in final edited form as: Nat Genet. 2018 Mar; 50(3): 460–471. Published online 2018 Feb 19. doi: 10.1038/s41588-018-0054-7
PMCID:
PMC5862771
AbstractArticlePDF–2.5M
13.
Cytosolic Hsp90α and its mitochondrial isoform Trap1 are differentially required in a breast cancer model
Evangelia Vartholomaiou, Marta Madon-Simon, Stéphane Hagmann, Guillaume Mühlebach, Wolfgang Wurst, Thomas Floss, Didier Picard
Oncotarget. 2017 Mar 14; 8(11): 17428–17442. Published online 2017 Feb 23. doi: 10.18632/oncotarget.15659
PMCID:
PMC5392260
AbstractArticlePDF–6.7M
14.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
15.
Transgenic Expression of the Mitochondrial Chaperone TNFR-associated Protein 1 (TRAP1) Accelerates Prostate Cancer Development
Sofia Lisanti, David S. Garlick, Kelly G. Bryant, Michele Tavecchio, Gordon B. Mills, Yiling Lu, Andrew V. Kossenkov, Louise C. Showe, Lucia R. Languino, Dario C. Altieri
J Biol Chem. 2016 Nov 25; 291(48): 25247–25254. Published online 2016 Oct 17. doi: 10.1074/jbc.M116.745950
PMCID:
PMC5122790
AbstractArticlePDF–2.6M
16.
Overexpression of mitochondrial Hsp75 protects neural stem cells against microglia-derived soluble factor-induced neurotoxicity by regulating mitochondrial permeability transition pore opening in vitro
YAN WANG, JIZONG LIN, QING-ZHUANG CHEN, NING ZHU, DE-QI JIANG, MING-XING LI, YONG WANG
Int J Mol Med. 2015 Dec; 36(6): 1487–1496. Published online 2015 Oct 19. doi: 10.3892/ijmm.2015.2380
PMCID:
PMC4678160
AbstractArticlePDF–1.3M
17.
Overexpression of tumor necrosis factor receptor-associated protein 1 (TRAP1), leads to mitochondrial aberrations in mouse fibroblast NIH/3T3 cells
Chang-Nim Im, Jeong-Sun Seo
BMB Rep. 2014 May; 47(5): 280–285. doi: 10.5483/BMBRep.2014.47.5.174
PMCID:
PMC4163861
AbstractArticlePDF–6.3M
18.
DELETION OF THE MITOCHONDRIAL CHAPERONE TRAP-1 UNCOVERS GLOBAL REPROGRAMMING OF METABOLIC NETWORKS
Sofia Lisanti, Michele Tavecchio, Young Chan Chae, Qin Liu, Angela K. Brice, Madhukar L. Thakur, Lucia R. Languino, Dario C. Altieri
Cell Rep. Author manuscript; available in PMC 2015 Aug 7.
Published in final edited form as: Cell Rep. 2014 Aug 7; 8(3): 671–677. Published online 2014 Jul 31. doi: 10.1016/j.celrep.2014.06.061
PMCID:
PMC4127146
AbstractArticlePDF–891K
19.
Whole exome resequencing reveals recessive mutations in TRAP1 in individuals with CAKUT and VACTERL association
Pawaree Saisawat, Stefan Kohl, Alina C. Hilger, Daw-Yang Hwang, Heon Yung Gee, Gabriel C. Dworschak, Velibor Tasic, Tracie Pennimpede, Sivakumar Natarajan, Ethan Sperry, Danilo S. Matassa, Nataša Stajic, Radovan Bogdanovic, Ivo de Blaauw, Carlo L.M. Marcelis, Charlotte H.W. Wijers, Enrika Bartels, Eberhard Schmiedeke, Dominik Schmidt, Stefanie Mäzheuser, Sabine Grasshoff-Derr, Stefan Holland-Cunz, Michael Ludwig, Markus M. Nöhen, Markus Draaken, Erwin Brosens, Hugo Heij, Dick Tibboel, Bernhard G. Herrmann, Benjamin D. Solomon, Annelies de Klein, Iris A.L.M. van Rooij, Franca Esposito, Heiko M. Reutter, Friedhelm Hildebrandt
Kidney Int. Author manuscript; available in PMC 2014 Dec 1.
Published in final edited form as: Kidney Int. 2014 Jun; 85(6): 1310–1317. Published online 2013 Oct 23. doi: 10.1038/ki.2013.417
PMCID:
PMC3997628
AbstractArticlePDF–2.8M
20.
Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis
Soichiro Yoshida, Shinji Tsutsumi, Guillaume Muhlebach, Carole Sourbier, Min-Jung Lee, Sunmin Lee, Evangelia Vartholomaiou, Manabu Tatokoro, Kristin Beebe, Naoto Miyajima, Robert P. Mohney, Yang Chen, Hisashi Hasumi, Wanping Xu, Hiroshi Fukushima, Ken Nakamura, Fumitaka Koga, Kazunori Kihara, Jane Trepel, Didier Picard, Leonard Neckers
Proc Natl Acad Sci U S A. 2013 Apr 23; 110(17): E1604–E1612. Published online 2013 Apr 5. doi: 10.1073/pnas.1220659110
PMCID:
PMC3637790
AbstractArticlePDF–1.4M

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