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Items: 1 to 20 of 340

1.
Advanced paternal age exacerbates neuroinflammation in offspring via m6A modification-mediated intergenerational inheritance
Yiting Mao, Yicong Meng, Kexin Zou, Ningxin Qin, Yinyu Wang, Jing Yan, PinJia Chen, Yi Cheng, Weihui Shi, Chengliang Zhou, Huixi Chen, Jianzhong Sheng, Xinmei Liu, Jiexue Pan, Hefeng Huang
J Neuroinflammation. 2024; 21: 249. Published online 2024 Oct 4. doi: 10.1186/s12974-024-03248-8
PMCID:
PMC11453047
AbstractArticlePDF–8.9M
2.
A single-cell transcriptomic landscape of cadmium-hindered brain development in mice
Qinlong Ma, Zhiqi Yang, Chuanyan Yang, Min Lin, Mingyue Gong, Ping Deng, Mindi He, Yonghui Lu, Kuan Zhang, Huifeng Pi, Mingyue Qu, Zhengping Yu, Zhou Zhou, Chunhai Chen
Commun Biol. 2024; 7: 997. Published online 2024 Aug 15. doi: 10.1038/s42003-024-06685-6
PMCID:
PMC11327346
AbstractArticlePDF–5.5M
3.
Membrane remodeling by FAM92A1 during brain development regulates neuronal morphology, synaptic function, and cognition
Liang Wang, Ziyun Yang, Fudo Satoshi, Xavier Prasanna, Ziyi Yan, Helena Vihinen, Yaxing Chen, Yue Zhao, Xiumei He, Qian Bu, Hongchun Li, Ying Zhao, Linhong Jiang, Feng Qin, Yanping Dai, Ni Zhang, Meng Qin, Weihong Kuang, Yinglan Zhao, Eija Jokitalo, Ilpo Vattulainen, Tommi Kajander, Hongxia Zhao, Xiaobo Cen
Nat Commun. 2024; 15: 6209. Published online 2024 Jul 23. doi: 10.1038/s41467-024-50565-w
PMCID:
PMC11266426
AbstractArticlePDF–18M
4.
Apaf1-deficient cortical neurons exhibit defects in axonal outgrowth
Daniela De Zio, Francesca Molinari, Salvatore Rizza, Lucia Gatta, Maria Teresa Ciotti, Anna Maria Salvatore, Søs Grønbæk Mathiassen, Andrzej W. Cwetsch, Giuseppe Filomeni, Giuseppe Rosano, Elisabetta Ferraro
Cell Mol Life Sci. 2015 Nov; 72(21): 4173–4191. Published online 2015 May 15. doi: 10.1007/s00018-015-1927-x
PMCID:
PMC11113842
AbstractArticlePDF–1.8M
5.
Slitrk4 is required for the development of inhibitory neurons in the fear memory circuit of the lateral amygdala
Yoshifumi Matsumoto, Hideki Miwa, Kei-ichi Katayama, Arata Watanabe, Kazuyuki Yamada, Takashi Ito, Shinsuke Nakagawa, Jun Aruga
Front Mol Neurosci. 2024; 17: 1386924. Published online 2024 Apr 26. doi: 10.3389/fnmol.2024.1386924
PMCID:
PMC11082273
AbstractArticlePDF–4.8M
6.
Hyperfunction of post-synaptic density protein 95 promotes seizure response in early-stage aβ pathology
Yeeun Yook, Kwan Young Lee, Eunyoung Kim, Simon Lizarazo, Xinzhu Yu, Nien-Pei Tsai
EMBO Rep. 2024 Mar; 25(3): 1233–1255. Published online 2024 Feb 27. doi: 10.1038/s44319-024-00090-0
PMCID:
PMC10933348
AbstractArticlePDF–3.8M
7.
FAM81A is a postsynaptic protein that regulates the condensation of postsynaptic proteins via liquid–liquid phase separation
Takeshi Kaizuka, Taisei Hirouchi, Takeo Saneyoshi, Toshihiko Shirafuji, Mark O. Collins, Seth G. N. Grant, Yasunori Hayashi, Toru Takumi
PLoS Biol. 2024 Mar; 22(3): e3002006. Published online 2024 Mar 7. doi: 10.1371/journal.pbio.3002006
PMCID:
PMC10919877
AbstractArticlePDF–5.4M
8.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
9.
Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
Nicole Fadahunsi, Jonas Petersen, Sophia Metz, Alexander Jakobsen, Cecilie Vad Mathiesen, Alberte Silke Buch-Rasmussen, Nigel Kurgan, Jeppe Kjærgaard Larsen, Rita C. Andersen, Thomas Topilko, Charlotte Svendsen, Mia Apuschkin, Grethe Skovbjerg, Jan Hendrik Schmidt, Grace Houser, Sara Elgaard Jager, Anders Bach, Atul S. Deshmukh, Tuomas O. Kilpeläinen, Kristian Strømgaard, Kenneth L. Madsen, Christoffer Clemmensen
Sci Adv. 2024 Mar 1; 10(9): eadg2636. Published online 2024 Mar 1. doi: 10.1126/sciadv.adg2636
PMCID:
PMC10906926
AbstractArticlePDF–6.4M
10.
Btbd11 supports cell-type-specific synaptic function
Alexei M. Bygrave, Ayesha Sengupta, Ella P. Jackert, Mehroz Ahmed, Beloved Adenuga, Erik Nelson, Hana L. Goldschmidt, Richard C. Johnson, Haining Zhong, Felix L. Yeh, Morgan Sheng, Richard L. Huganir
Cell Rep. Author manuscript; available in PMC 2023 Oct 23.
Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112591. Published online 2023 May 31. doi: 10.1016/j.celrep.2023.112591
PMCID:
PMC10592477
AbstractArticlePDF–3.6M
11.
Uncovering a mammalian neural-specific poly(A) binding protein with unique properties
Sahil Sharma, Sam Kajjo, Zineb Harra, Benedeta Hasaj, Victoria Delisle, Debashish Ray, Rodrigo L. Gutierrez, Isabelle Carrier, Claudia Kleinman, Quaid Morris, Timothy R. Hughes, Roderick McInnes, Marc R. Fabian
Genes Dev. 2023 Aug 1; 37(15-16): 760–777. doi: 10.1101/gad.350597.123
PMCID:
PMC10546976
AbstractArticlePDF–5.4M
12.
Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex
Iva Salamon, Yongkyu Park, Terezija Miškić, Janja Kopić, Paul Matteson, Nicholas F. Page, Alfonso Roque, Geoffrey W. McAuliffe, John Favate, Marta Garcia-Forn, Premal Shah, Miloš Judaš, James H. Millonig, Ivica Kostović, Silvia De Rubeis, Ronald P. Hart, Željka Krsnik, Mladen-Roko Rasin
Nat Commun. 2023; 14: 6025. Published online 2023 Sep 27. doi: 10.1038/s41467-023-41730-8
PMCID:
PMC10533865
AbstractArticlePDF–4.9M
13.
TRIM67 Implicates in Regulating the Homeostasis and Synaptic Development of Mitral Cells in the Olfactory Bulb
Chunyu Cai, Qihui Luo, Lanlan Jia, Yu Xia, Xinting Lan, Xiaoli Wei, Shuai Shi, Yucong Liu, Yao Wang, Zongliang Xiong, Riyi Shi, Chao Huang, Zhengli Chen
Int J Mol Sci. 2023 Sep; 24(17): 13439. Published online 2023 Aug 30. doi: 10.3390/ijms241713439
PMCID:
PMC10487898
AbstractArticlePDF–7.5M
14.
Defective neurite elongation and branching in Nibp/Trappc9 deficient zebrafish and mice
Min Hu, Brittany Bodnar, Yonggang Zhang, Fangxin Xie, Fang Li, Siying Li, Jin Zhao, Ruotong Zhao, Naveen Gedupoori, Yifan Mo, Lanyi Lin, Xue Li, Wentong Meng, Xiaofeng Yang, Hong Wang, Mary F. Barbe, Shanthi Srinivasan, John R. Bethea, Xianming Mo, Hong Xu, Wenhui Hu
Int J Biol Sci. 2023; 19(10): 3226–3248. Published online 2023 Jun 19. doi: 10.7150/ijbs.78489
PMCID:
PMC10321293
AbstractArticlePDF–10M
15.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
16.
The mRNA translation initiation factor eIF4G1 controls mitochondrial oxidative phosphorylation, axonal morphogenesis, and memory
Sung-Hoon Kim, Jung-Hyun Choi, Laura Marsal-García, Mehdi Amiri, Akiko Yanagiya, Nahum Sonenberg
Proc Natl Acad Sci U S A. 2023 Jun 20; 120(25): e2300008120. Published online 2023 Jun 12. doi: 10.1073/pnas.2300008120
PMCID:
PMC10288579
AbstractArticlePDF–4.2M
17.
Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome
Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh
Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5
PMCID:
PMC10208958
AbstractArticlePDF–7.0M
18.
Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex
Martin Munz, Arjun Bharioke, Georg Kosche, Verónica Moreno-Juan, Alexandra Brignall, Tiago M. Rodrigues, Alexandra Graff-Meyer, Talia Ulmer, Stephanie Haeuselmann, Dinko Pavlinic, Nicole Ledergerber, Brigitte Gross-Scherf, Balázs Rózsa, Jacek Krol, Simone Picelli, Cameron S. Cowan, Botond Roska
Cell. 2023 Apr 27; 186(9): 1930–1949.e31. doi: 10.1016/j.cell.2023.03.025
PMCID:
PMC10156177
AbstractArticle
19.
A brain atlas of synapse protein lifetime across the mouse lifespan
Edita Bulovaite, Zhen Qiu, Maximilian Kratschke, Adrianna Zgraj, David G. Fricker, Eleanor J. Tuck, Ragini Gokhale, Babis Koniaris, Shekib A. Jami, Paula Merino-Serrais, Elodie Husi, Lorena Mendive-Tapia, Marc Vendrell, Thomas J. O’Dell, Javier DeFelipe, Noboru H. Komiyama, Anthony Holtmaat, Erik Fransén, Seth G.N. Grant
Neuron. Author manuscript; available in PMC 2023 Dec 21.
Published in final edited form as: Neuron. 2022 Dec 21; 110(24): 4057–4073.e8. Published online 2022 Oct 5. doi: 10.1016/j.neuron.2022.09.009
PMCID:
PMC9789179
AbstractArticlePDF–2.4M
20.
KIF2A deficiency causes early-onset neurodegeneration
Nuria Ruiz-Reig, Georges Chehade, Janne Hakanen, Mohamed Aittaleb, Keimpe Wierda, Joris De Wit, Laurent Nguyen, Philippe Gailly, Fadel Tissir
Proc Natl Acad Sci U S A. 2022 Nov 15; 119(46): e2209714119. Published online 2022 Nov 7. doi: 10.1073/pnas.2209714119
PMCID:
PMC9674219
AbstractArticlePDF–3.8M

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