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Items: 1 to 20 of 59

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Functional role of Ash2l in oxLDL induced endothelial dysfunction and atherosclerosis
Zhenghua Su, Jinghuan Wang, Chenxi Xiao, Wen Zhong, Jiayao Liu, Xinhua Liu, Yi Zhun Zhu
Cell Mol Life Sci. 2024 Dec; 81(1): 62. Published online 2024 Jan 27. doi: 10.1007/s00018-024-05130-5
PMCID:
PMC10821849
AbstractArticlePDF–16M
3.
ASH2L regulates postnatal neurogenesis through Onecut2-mediated inhibition of TGF-β signaling pathway
Ya-Jie Xu, Shang-Kun Dai, Chun-Hui Duan, Zi-Han Zhang, Pei-Pei Liu, Cong Liu, Hong-Zhen Du, Xu-Kun Lu, Shijun Hu, Lei Li, Zhao-Qian Teng, Chang-Mei Liu
Cell Death Differ. 2023 Aug; 30(8): 1943–1956. Published online 2023 Jul 11. doi: 10.1038/s41418-023-01189-y
PMCID:
PMC10406892
AbstractArticlePDF–8.2M
4.
ASH2L Controls Ureteric Bud Morphogenesis through the Regulation of RET/GFRA1 Signaling Activity in a Mouse Model
Ziyi Zhao, Xuantong Dai, Gengru Jiang, Fujun Lin
J Am Soc Nephrol. 2023 Jun; 34(6): 988–1002. Published online 2023 Feb 9. doi: 10.1681/ASN.0000000000000099
PMCID:
PMC10278782
AbstractArticle
5.
ASH2L Aggravates Fibrosis and Inflammation through HIPK2 in High Glucose-Induced Glomerular Mesangial Cells
Wen Zhong, Chen Hong, Yejun Dong, Yuhui Li, Chenxi Xiao, Xinhua Liu
Genes (Basel) 2022 Dec; 13(12): 2244. Published online 2022 Nov 29. doi: 10.3390/genes13122244
PMCID:
PMC9816940
AbstractArticlePDF–7.5M
6.
Loss of the Ash2l subunit of histone H3K4 methyltransferase complexes reduces chromatin accessibility at promoters
Mirna Barsoum, Alexander T. Stenzel, Agnieszka Bochyńska, Chao-Chung Kuo, Alexander Tsompanidis, Roksaneh Sayadi-Boroujeni, Philip Bussmann, Juliane Lüscher-Firzlaff, Ivan G. Costa, Bernhard Lüscher
Sci Rep. 2022; 12: 21506. Published online 2022 Dec 13. doi: 10.1038/s41598-022-25881-0
PMCID:
PMC9747801
AbstractArticlePDF–3.8M
7.
Induction of senescence upon loss of the Ash2l core subunit of H3K4 methyltransferase complexes
Agnieszka Bochyńska, Alexander T Stenzel, Roksaneh Sayadi Boroujeni, Chao-Chung Kuo, Mirna Barsoum, Weili Liang, Philip Bussmann, Ivan G Costa, Juliane Lüscher-Firzlaff, Bernhard Lüscher
Nucleic Acids Res. 2022 Aug 12; 50(14): 7889–7905. Published online 2022 Jul 12. doi: 10.1093/nar/gkac591
PMCID:
PMC9371893
AbstractArticlePDF–2.7M
8.
The Ash2l SDI Domain Is Required to Maintain the Stability and Binding of DPY30
Mengjie Ma, Jiafeng Zhou, Zhihua Ma, Hanxue Chen, Liang Li, Lin Hou, Bin Yin, Boqin Qiang, Pengcheng Shu, Xiaozhong Peng
Cells. 2022 May; 11(9): 1450. Published online 2022 Apr 25. doi: 10.3390/cells11091450
PMCID:
PMC9103646
AbstractArticlePDF–2.4M
9.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
10.
Smyd1 Orchestrates Early Heart Development Through Positive and Negative Gene Regulation
Zhen Wang, Robert J. Schwartz, Jing Liu, Fei Sun, Qi Li, Yanlin Ma
Front Cell Dev Biol. 2021; 9: 654682. Published online 2021 Apr 1. doi: 10.3389/fcell.2021.654682
PMCID:
PMC8047137
AbstractArticlePDF–2.1M
11.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
12.
Ash2l interacts with Oct4-stemness circuitry to promote super-enhancer-driven pluripotency network
Ping-Hsing Tsai, Yueh Chien, Mong-Lien Wang, Chih-Hung Hsu, Benoit Laurent, Shih-Jie Chou, Wei-Chao Chang, Chian-Shiu Chien, Hsin-Yang Li, Hsin-Chen Lee, Teh-Ia Huo, Jui-Hung Hung, Chung-Hsuan Chen, Shih-Hwa Chiou
Nucleic Acids Res. 2019 Nov 4; 47(19): 10115–10133. Published online 2019 Sep 26. doi: 10.1093/nar/gkz801
PMCID:
PMC6821267
AbstractArticlePDF–5.0M
13.
Hematopoietic stem and progenitor cell proliferation and differentiation requires the trithorax protein Ash2l
Juliane Lüscher-Firzlaff, Nicolas Chatain, Chao-Chung Kuo, Till Braunschweig, Agnieszka Bochyńska, Andrea Ullius, Bernd Denecke, Ivan G. Costa, Steffen Koschmieder, Bernhard Lüscher
Sci Rep. 2019; 9: 8262. Published online 2019 Jun 4. doi: 10.1038/s41598-019-44720-3
PMCID:
PMC6547667
AbstractArticlePDF–7.8M
14.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
15.
Disruption of OCT4 Ubiquitination Increases OCT4 Protein Stability and ASH2L-B-Mediated H3K4 Methylation Promoting Pluripotency Acquisition
Shuang Li, Feng Xiao, Junmei Zhang, Xiaozhi Sun, Han Wang, Yanwu Zeng, Jing Hu, Fan Tang, Junjie Gu, Yingming Zhao, Ying Jin, Bing Liao
Stem Cell Reports. 2018 Oct 9; 11(4): 973–987. Published online 2018 Sep 27. doi: 10.1016/j.stemcr.2018.09.001
PMCID:
PMC6178847
AbstractArticlePDF–4.1M
16.
The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1
Gina E. Elsen, Francesco Bedogni, Rebecca D. Hodge, Theo K. Bammler, James W. MacDonald, Susan Lindtner, John L. R. Rubenstein, Robert F. Hevner
Front Neurosci. 2018; 12: 571. Published online 2018 Aug 22. doi: 10.3389/fnins.2018.00571
PMCID:
PMC6113890
AbstractArticlePDF–4.8M
17.
Whole-transcriptome splicing profiling of E7.5 mouse primary germ layers reveals frequent alternative promoter usage during mouse early embryogenesis
Xukun Lu, Zhen-Ao Zhao, Xiaoqing Wang, Xiaoxin Zhang, Yanhua Zhai, Wenbo Deng, Zhaohong Yi, Lei Li
Biol Open. 2018 Mar 15; 7(3): bio032508. Published online 2018 Mar 15. doi: 10.1242/bio.032508
PMCID:
PMC5898269
AbstractArticlePDF–3.3M
18.
Xist RNA repeat E is essential for ASH2L recruitment to the inactive X and regulates histone modifications and escape gene expression
Minghui Yue, Akiyo Ogawa, Norishige Yamada, John Lalith Charles Richard, Artem Barski, Yuya Ogawa
PLoS Genet. 2017 Jul; 13(7): e1006890. Published online 2017 Jul 7. doi: 10.1371/journal.pgen.1006890
PMCID:
PMC5521851
AbstractArticlePDF–5.9M
19.
MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function
David W. Scoville, Holly A. Cyphert, Lan Liao, Jianming Xu, Al Reynolds, Shuangli Guo, Roland Stein
Diabetes. 2015 Nov; 64(11): 3772–3783. Published online 2015 Jul 15. doi: 10.2337/db15-0281
PMCID:
PMC4613979
AbstractArticlePDF–1.5M
20.
Evolving Catalytic Properties of the MLL Family SET Domain
Ying Zhang, Anshumali Mittal, James Reid, Stephanie Reich, Steven J. Gamblin, Jon R. Wilson
Structure. 2015 Oct 6; 23(10): 1921–1933. doi: 10.1016/j.str.2015.07.018
PMCID:
PMC4597100
AbstractArticle

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