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Select item 113994071.

Conserved transcriptional regulation by BRN1 and BRN2 in neocortical progenitors drives mammalian neural specification and neocortical expansion

Soraia Barão, Yijun Xu, José P. Llongueras, Rachel Vistein, Loyal Goff, Kristina J. Nielsen, Byoung-Il Bae, Richard S. Smith, Christopher A. Walsh, Genevieve Stein-O’Brien, Ulrich Müller

Nat Commun. 2024; 15: 8043. Published online 2024 Sep 14. doi: 10.1038/s41467-024-52443-x

PMCID:: PMC11399407

Abstract Article PDF–12M

Select item 111141962.

A global gene regulatory program and its region-specific regulator partition neurons into commissural and ipsilateral projection types

Aki Masuda, Kazuhiko Nishida, Rieko Ajima, Yumiko Saga, Marah Bakhtan, Avihu Klar, Tatsumi Hirata, Yan Zhu

Sci Adv. 2024 May 24; 10(21): eadk2149. Published online 2024 May 23. doi: 10.1126/sciadv.adk2149

PMCID:: PMC11114196

Abstract Article PDF–7.7M

Select item 110480973.

Mice Mutated in the First Fibronectin Domain of Adhesion Molecule L1 Show Brain Malformations and Behavioral Abnormalities

Viviana Granato, Ludovica Congiu, Igor Jakovcevski, Ralf Kleene, Benjamin Schwindenhammer, Luciana Fernandes, Sandra Freitag, Melitta Schachner, Gabriele Loers

Biomolecules. 2024 Apr; 14(4): 468. Published online 2024 Apr 11. doi: 10.3390/biom14040468

PMCID:: PMC11048097

Abstract Article PDF–3.5M

Select item 109464384.

EphB1 controls long-range cortical axon guidance through a cell non-autonomous role in GABAergic cells

Ahlem Assali, George Chenaux, Jennifer Y. Cho, Stefano Berto, Nathan A. Ehrlich, Christopher W. Cowan

Development. 2024 Mar 1; 151(5): dev201439. Published online 2024 Feb 28. doi: 10.1242/dev.201439

PMCID:: PMC10946438

Abstract Article

Select item 104316855.

An adhesion signaling axis involving Dystroglycan, β1-Integrin, and Cas adaptor proteins regulates the establishment of the cortical glial scaffold

Wenny Wong, Jason A. Estep, Alyssa M. Treptow, Niloofar Rajabli, Jennifer N. Jahncke, Teresa Ubina, Kevin M. Wright, Martin M. Riccomagno

PLoS Biol. 2023 Aug; 21(8): e3002212. Published online 2023 Aug 4. doi: 10.1371/journal.pbio.3002212

PMCID:: PMC10431685

Abstract Article PDF–12M

Select item 103095806.

Notch directs telencephalic development and controls neocortical neuron fate determination by regulating microRNA levels

Jisoo S. Han, Elizabeth Fishman-Williams, Steven C. Decker, Keiko Hino, Raenier V. Reyes, Nadean L. Brown, Sergi Simó, Anna La Torre

Development. 2023 Jun 1; 150(11): dev201408. Published online 2023 Jun 5. doi: 10.1242/dev.201408

PMCID:: PMC10309580

Abstract Article

Select item 103078527.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 102165918.

Histological Analysis of a Mouse Model of the 22q11.2 Microdeletion Syndrome

Hidenori Tabata, Daisuke Mori, Tohru Matsuki, Kaichi Yoshizaki, Masato Asai, Atsuo Nakayama, Norio Ozaki, Koh-ichi Nagata

Biomolecules. 2023 May; 13(5): 763. Published online 2023 Apr 27. doi: 10.3390/biom13050763

PMCID:: PMC10216591

Abstract Article PDF–4.2M

Select item 102160339.

Mice Mutated in the Third Fibronectin Domain of L1 Show Enhanced Hippocampal Neuronal Cell Death, Astrogliosis and Alterations in Behavior

Ludovica Congiu, Viviana Granato, Igor Jakovcevski, Ralf Kleene, Luciana Fernandes, Sandra Freitag, Matthias Kneussel, Melitta Schachner, Gabriele Loers

Biomolecules. 2023 May; 13(5): 776. Published online 2023 Apr 29. doi: 10.3390/biom13050776

PMCID:: PMC10216033

Abstract Article PDF–3.2M

Select item 1014783610.

Viral delivery of L1CAM promotes axonal extensions by embryonic cerebral grafts in mouse brain

Ryosuke Tsuchimochi, Keitaro Yamagami, Naoko Kubo, Naoya Amimoto, Fabian Raudzus, Bumpei Samata, Tetsuhiro Kikuchi, Daisuke Doi, Koji Yoshimoto, Aya Mihara, Jun Takahashi

Stem Cell Reports. 2023 Apr 11; 18(4): 899–914. Published online 2023 Mar 23. doi: 10.1016/j.stemcr.2023.02.012

PMCID:: PMC10147836

Abstract Article PDF–9.1M

Select item 992286911.

Differential impacts of Cntnap2 heterozygosity and Cntnap2 null homozygosity on axon and myelinated fiber development in mouse

Carmen Cifuentes-Diaz, Giorgia Canali, Marta Garcia, Mélanie Druart, Taylor Manett, Mythili Savariradjane, Camille Guillaume, Corentin Le Magueresse, Laurence Goutebroze

Front Neurosci. 2023; 17: 1100121. Published online 2023 Jan 30. doi: 10.3389/fnins.2023.1100121

PMCID:: PMC9922869

Abstract Article PDF–6.4M

Select item 991682812.

The Interactions of the 70 kDa Fragment of Cell Adhesion Molecule L1 with Topoisomerase 1, Peroxisome Proliferator-Activated Receptor γ and NADH Dehydrogenase (Ubiquinone) Flavoprotein 2 Are Involved in Gene Expression and Neuronal L1-Dependent Functions

Gabriele Loers, Ralf Kleene, Ute Bork, Melitta Schachner

Int J Mol Sci. 2023 Feb; 24(3): 2097. Published online 2023 Jan 20. doi: 10.3390/ijms24032097

PMCID:: PMC9916828

Abstract Article PDF–2.8M

Select item 986638113.

The KDET Motif in the Intracellular Domain of the Cell Adhesion Molecule L1 Interacts with Several Nuclear, Cytoplasmic, and Mitochondrial Proteins Essential for Neuronal Functions

Ralf Kleene, Gabriele Loers, Melitta Schachner

Int J Mol Sci. 2023 Jan; 24(2): 932. Published online 2023 Jan 4. doi: 10.3390/ijms24020932

PMCID:: PMC9866381

Abstract Article PDF–2.4M

Select item 946313114.

SLITRK1-mediated noradrenergic projection suppression in the neonatal prefrontal cortex

Minoru Hatayama, Kei-ichi Katayama, Yukie Kawahara, Hayato Matsunaga, Noriko Takashima, Yoshimi Iwayama, Yoshifumi Matsumoto, Akinori Nishi, Takeo Yoshikawa, Jun Aruga

Commun Biol. 2022; 5: 935. Published online 2022 Sep 9. doi: 10.1038/s42003-022-03891-y

PMCID:: PMC9463131

Abstract Article PDF–4.1M

Select item 937173115.

Postmitotic accumulation of histone variant H3.3 in new cortical neurons establishes neuronal chromatin, transcriptome, and identity

Owen H. Funk, Yaman Qalieh, Daniel Z. Doyle, Mandy M. Lam, Kenneth Y. Kwan

Proc Natl Acad Sci U S A. 2022 Aug 9; 119(32): e2116956119. Published online 2022 Aug 5. doi: 10.1073/pnas.2116956119

PMCID:: PMC9371731

Abstract Article PDF–7.3M

Select item 935266716.

Ca²⁺ homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling

Ke-Yan Yang, Song Zhao, Haiping Feng, Jiaqi Shen, Yuwei Chen, Si-Tong Wang, Si-Jia Wang, Yu-Xin Zhang, Yun Wang, Caixia Guo, Hongmei Liu, Tie-Shan Tang

Cell Death Dis. 2022 Aug; 13(8): 674. Published online 2022 Aug 4. doi: 10.1038/s41419-022-05131-x