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Items: 1 to 20 of 226

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Regulatory T cells targeting a pathogenic MHC class II: Insulin peptide epitope postpone spontaneous autoimmune diabetes
Nyerhovwo Obarorakpor, Deep Patel, Reni Boyarov, Nansalmaa Amarsaikhan, Joseph Ray Cepeda, Doreen Eastes, Sylvia Robertson, Travis Johnson, Kai Yang, Qizhi Tang, Li Zhang
Front Immunol. 2023; 14: 1207108. Published online 2023 Aug 1. doi: 10.3389/fimmu.2023.1207108
Correction in:
Front Immunol. 2024; 15: 1391518.
PMCID:
PMC10428008
AbstractArticlePDF–6.4M
3.
Cis-B7:CD28 Interactions at Invaginated Synaptic Membranes Activate CD28 and Promote CD8+ T Cell Function and Anti-Tumor Immunity
Yunlong Zhao, Christine Caron, Ya-Yuan Chan, Calvin K. Lee, Xiaozheng Xu, Jibin Zhang, Takeya Masubuchi, Chuan Wu, Jack D. Bui, Enfu Hui
Immunity. Author manuscript; available in PMC 2024 Jun 13.
Published in final edited form as: Immunity. 2023 Jun 13; 56(6): 1187–1203.e12. Published online 2023 May 8. doi: 10.1016/j.immuni.2023.04.005
PMCID:
PMC10330546
AbstractArticlePDF–4.1M
4.
CD28-signaling can be partially compensated in CD28-knockout mice but is essential for virus elimination in a murine model of multiple sclerosis
Kirsten Hülskötter, Fred Lühder, Eva Leitzen, Alexander Flügel, Wolfgang Baumgärtner
Front Immunol. 2023; 14: 1105432. Published online 2023 Apr 5. doi: 10.3389/fimmu.2023.1105432
PMCID:
PMC10113529
AbstractArticlePDF–21M
5.
Antigen-presenting T cells provide critical B7 co-stimulation for thymic iNKT cell development via CD28-dependent trogocytosis
Masashi Watanabe, Sofia Celli, Farrah A. Alkhaleel, Richard J. Hodes
Cell Rep. Author manuscript; available in PMC 2022 Dec 31.
Published in final edited form as: Cell Rep. 2022 Nov 29; 41(9): 111731. doi: 10.1016/j.celrep.2022.111731
PMCID:
PMC9805342
AbstractArticlePDF–2.1M
6.
Costimulatory and coinhibitory molecules of B7-CD28 family in cardiovascular atherosclerosis: A review
Mao Yang, Simeng Tian, Zhoujun Lin, Zhenkun Fu, Chenggang Li
Medicine (Baltimore) 2022 Nov 11; 101(45): e31667. Published online 2022 Nov 11. doi: 10.1097/MD.0000000000031667
PMCID:
PMC9666218
AbstractArticlePDF–506K
7.
Forced expression of the non-coding RNA miR-17∼92 restores activation and function in CD28-deficient CD4+ T cells
Marianne Dölz, Marko Hasiuk, John D. Gagnon, Mara Kornete, Romina Marone, Glenn Bantug, Robin Kageyama, Christoph Hess, K. Mark Ansel, Denis Seyres, Julien Roux, Lukas T. Jeker
iScience. 2022 Nov 18; 25(11): 105372. Published online 2022 Oct 17. doi: 10.1016/j.isci.2022.105372
PMCID:
PMC9646923
AbstractArticlePDF–5.6M
8.
Indoleamine 2,3-dioxygenase 1 is Essential for Sustaining Durable Antibody Responses
Shivana M. Lightman, Jennifer L. Peresie, Louise M. Carlson, G. Aaron Holling, Mackenzie M. Honikel, Colin A. Chavel, Michael J Nemeth, Scott H. Olejniczak, Kelvin P. Lee
Immunity. Author manuscript; available in PMC 2022 Dec 14.
Published in final edited form as: Immunity. 2021 Dec 14; 54(12): 2772–2783.e5. Published online 2021 Nov 16. doi: 10.1016/j.immuni.2021.10.005
PMCID:
PMC9323746
AbstractArticlePDF–2.2M
9.
Extrafollicular Plasmablasts Present in the Acute Phase of Infections Express High Levels of PD-L1 and Are Able to Limit T Cell Response
Melisa Gorosito Serrán, Facundo Fiocca Vernengo, Laura Almada, Cristian G. Beccaria, Yamila Gazzoni, Pablo F. Canete, Jonathan A. Roco, Jimena Tosello Boari, Maria Cecilia Ramello, Ellen Wehrens, Yeping Cai, Elina I. Zuniga, Carolina L. Montes, Ian A. Cockburn, Eva V. Acosta Rodriguez, Carola G. Vinuesa, Adriana Gruppi
Front Immunol. 2022; 13: 828734. Published online 2022 May 16. doi: 10.3389/fimmu.2022.828734
PMCID:
PMC9149371
AbstractArticlePDF–5.6M
10.
The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming
Sophia M. Hochrein, Hao Wu, Miriam Eckstein, Laura Arrigoni, Josip S. Herman, Fabian Schumacher, Christian Gerecke, Mathias Rosenfeldt, Dominic Grün, Burkhard Kleuser, Georg Gasteiger, Wolfgang Kastenmüller, Bart Ghesquière, Jan Van den Bossche, E. Dale Abel, Martin Vaeth
Cell Metab. Author manuscript; available in PMC 2023 Apr 5.
Published in final edited form as: Cell Metab. 2022 Apr 5; 34(4): 516–532.e11. Published online 2022 Mar 21. doi: 10.1016/j.cmet.2022.02.015
PMCID:
PMC9019065
AbstractArticlePDF–1.8M
11.
TRAF3 in T cells restrains negative regulators of LAT to promote TCR/CD28 signaling
Tina Arkee, Bruce S. Hostager, Jon C.D. Houtman, Gail A. Bishop
J Immunol. Author manuscript; available in PMC 2022 Jul 1.
Published in final edited form as: J Immunol. 2021 Jul 1; 207(1): 322–332. Published online 2021 Jun 18. doi: 10.4049/jimmunol.2001220
PMCID:
PMC8683566
AbstractArticlePDF–818K
12.
Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop
Francesco Marangoni, Ademi Zhakyp, Michela Corsini, Shannon N. Geels, Esteban Carrizosa, Martin Thelen, Vinidhra Mani, Jasper N. Prüßmann, Ross D. Warner, Aleksandra J. Ozga, Mauro Di Pilato, Shivashankar Othy, Thorsten R. Mempel
Cell. Author manuscript; available in PMC 2022 Jul 22.
Published in final edited form as: Cell. 2021 Jul 22; 184(15): 3998–4015.e19. Published online 2021 Jun 21. doi: 10.1016/j.cell.2021.05.027
PMCID:
PMC8664158
AbstractArticlePDF–2.6M
13.
ACTH treatment promotes murine cardiac allograft acceptance
Jing Zhao, Liwei Jiang, Mayuko Uehara, Naima Banouni, Basmah S. Al Dulaijan, Jamil Azzi, Takaharu Ichimura, Xiaofei Li, Petr Jarolim, Paolo Fiorina, Stefan G. Tullius, Joren C. Madsen, Vivek Kasinath, Reza Abdi
JCI Insight. 2021 Jul 8; 6(13): e143385. Published online 2021 Jul 8. doi: 10.1172/jci.insight.143385
PMCID:
PMC8410061
AbstractArticlePDF–12M
14.
Absence of CD28-CTLA4-PD-L1 Costimulatory Molecules Reduces Herpes Simplex Virus 1 Reactivation
Harry H. Matundan, Ujjaldeep Jaggi, Jack Yu, Omid Akbari, Homayon Ghiasi
mBio. 2021 Jul-Aug; 12(4): e01176-21. Published online 2021 Jul 20. doi: 10.1128/mBio.01176-21
PMCID:
PMC8406230
AbstractArticlePDF–3.5M
15.
Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy
Vivien Béziat, Franck Rapaport, Jiafen Hu, Matthias Titeux, Mathilde Bonnet des Claustres, Mathieu Bourgey, Heather Griffin, Élise Bandet, Cindy S. Ma, Roya Sherkat, Hassan Rokni-Zadeh, David M. Louis, Majid Changi-Ashtiani, Ottavia M. Delmonte, Toshiaki Fukushima, Tanwir Habib, Andrea Guennoun, Taushif Khan, Noemi Bender, Mahbuba Rahman, Frédégonde About, Rui Yang, Geetha Rao, Claire Rouzaud, Jingwei Li, Debra Shearer, Karla Balogh, Fatima Al Ali, Manar Ata, Soroosh Dabiri, Mana Momenilandi, Justine Nammour, Marie-Alexandra Alyanakian, Marianne Leruez-Ville, David Guenat, Marie Materna, Léa Marcot, Natasha Vladikine, Christine Soret, Hassan Vahidnezhad, Leila Youssefian, Amir Hossein Saeidian, Jouni Uitto, Émilie Catherinot, Shadi Sadat Navabi, Mohammed Zarhrate, David T. Woodley, Mohamed Jeljeli, Thomas Abraham, Serkan Belkaya, Lazaro Lorenzo, Jérémie Rosain, Mousa Bayat, Fanny Lanternier, Olivier Lortholary, Faramarz Zakavi, Philippe Gros, Gérard Orth, Laurent Abel, Jean-Luc Prétet, Sylvie Fraitag, Emmanuelle Jouanguy, Mark M. Davis, Stuart G. Tangye, Luigi D. Notarangelo, Nico Marr, Tim Waterboer, David Langlais, John Doorbar, Alain Hovnanian, Neil Christensen, Xavier Bossuyt, Mohammad Shahrooei, Jean-Laurent Casanova
Cell. Author manuscript; available in PMC 2022 Jul 8.
Published in final edited form as: Cell. 2021 Jul 8; 184(14): 3812–3828.e30. Published online 2021 Jul 1. doi: 10.1016/j.cell.2021.06.004
PMCID:
PMC8329841
AbstractArticlePDF–3.7M
16.
P2Y2 Receptor Antagonism Resolves Sialadenitis and Improves Salivary Flow in a Sjögren’s Syndrome Mouse Model
Kimberly J. Jasmer, Lucas T. Woods, Kevin Muñoz Forti, Adam L. Martin, Jean M. Camden, Marco Colonna, Gary A. Weisman
Arch Oral Biol. Author manuscript; available in PMC 2022 Apr 1.
Published in final edited form as: Arch Oral Biol. 2021 Apr; 124: 105067. Published online 2021 Feb 3. doi: 10.1016/j.archoralbio.2021.105067
PMCID:
PMC7958986
AbstractArticlePDF–1.7M
17.
CD28 agonism improves survival in immunologically experienced septic mice via IL-10 released by Foxp3+ regulatory T cells
Yini Sun, Jianfeng Xie, Jerome C. Anyalebechi, Ching-wen Chen, He Sun, Ming Xue, Zhe Liang, Kristen N. Morrow, Craig M. Coopersmith, Mandy L. Ford
J Immunol. Author manuscript; available in PMC 2021 Dec 15.
Published in final edited form as: J Immunol. 2020 Dec 15; 205(12): 3358–3371. Published online 2020 Nov 6. doi: 10.4049/jimmunol.2000595
PMCID:
PMC7725929
AbstractArticlePDF–2.2M
18.
TFR-derived Fibrinogen-like Protein 2 regulates production of autoantibodies and induction of systemic autoimmunity
Waradon Sungnak, Allon Wagner, Monika S. Kowalczyk, Lloyd Bod, Yoon-Chul Kye, Peter T. Sage, Arlene H. Sharpe, Raymond A. Sobel, Francisco J. Quintana, Orit Rozenblatt-Rosen, Aviv Regev, Chao Wang, Nir Yosef, Vijay K. Kuchroo
J Immunol. Author manuscript; available in PMC 2021 Dec 15.
Published in final edited form as: J Immunol. 2020 Dec 15; 205(12): 3247–3262. Published online 2020 Nov 9. doi: 10.4049/jimmunol.2000748
PMCID:
PMC7725915
AbstractArticlePDF–3.2M
19.
B7-CD28 co-stimulation modulates central tolerance via thymic clonal deletion and Treg generation through distinct mechanisms
Masashi Watanabe, Ying Lu, Michael Breen, Richard J. Hodes
Nat Commun. 2020; 11: 6264. Published online 2020 Dec 8. doi: 10.1038/s41467-020-20070-x
PMCID:
PMC7722925
AbstractArticlePDF–1.5M
20.
Superior inhibition of alloantibody responses with selective CD28 blockade is CTLA-4-dependent and T follicular helper cell-specific
G. Michael La Muraglia, II, Susan Zeng, Emma S. Crichton, Maylene E. Wagener, Mandy L. Ford, I. Raul Badell
Am J Transplant. Author manuscript; available in PMC 2022 Jan 1.
Published in final edited form as: Am J Transplant. 2021 Jan; 21(1): 73–86. Published online 2020 Jun 11. doi: 10.1111/ajt.16004
PMCID:
PMC7665991
AbstractArticlePDF–2.0M

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