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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 106921822.

Intrinsic factors and CD1d1 but not CD1d2 expression levels control invariant natural killer T cell subset differentiation

Ludivine Amable, Luis Antonio Ferreira Martins, Remi Pierre, Marcio Do Cruseiro, Ghita Chabab, Arnauld Sergé, Camille Kergaravat, Marc Delord, Christophe Viret, Jean Jaubert, Chaohong Liu, Saoussen Karray, Julien C. Marie, Magali Irla, Hristo Georgiev, Emmanuel Clave, Antoine Toubert, Bruno Lucas, Jihene Klibi, Kamel Benlagha

Nat Commun. 2023; 14: 7922. Published online 2023 Dec 1. doi: 10.1038/s41467-023-43424-7

PMCID:: PMC10692182

Abstract Article PDF–4.6M

Select item 105270423.

Lipids regulate peripheral serotonin release via gut CD1d

Jialie Luo, Zuojia Chen, David Castellano, Bin Bao, Wenyan Han, Jian Li, Girak Kim, Dingding An, Wei Lu, Chuan Wu

Immunity. Author manuscript; available in PMC 2024 Jul 11.

Published in final edited form as: Immunity. 2023 Jul 11; 56(7): 1533–1547.e7. Published online 2023 Jun 23. doi: 10.1016/j.immuni.2023.06.001

PMCID:: PMC10527042

Abstract Article PDF–2.6M

Select item 103560884.

CD1d‐Dependent Natural Killer T Cells Mediate Hypertension and Vascular Injury Through Interleukin‐17A

Xue Xiao, Cui‐Liu Hou, Yun‐Long Zhang, Hui Yang, Xiao‐Xiao Wang, Hong‐Xia Wang

J Am Heart Assoc. 2023 Jul 4; 12(13): e029179. Published online 2023 Jun 29. doi: 10.1161/JAHA.122.029179

PMCID:: PMC10356088

Abstract Article PDF–6.0M

Select item 102657465.

Critical Role for CD1d-Restricted Invariant NKT Cells in Stimulating Intrahepatic CD8 T-Cell Responses to Liver Antigen

DAVE SPRENGERS, FENNA C. M. SILLÉ, KATJA DERKOW, GURDYAL S. BESRA, HARRY L. A. JANSSEN, ECKART SCHOTT, MARIANNE BOES

Gastroenterology. Author manuscript; available in PMC 2023 Jun 14.

Published in final edited form as: Gastroenterology. 2008 Jun; 134(7): 2132–2143. Published online 2008 Feb 21. doi: 10.1053/j.gastro.2008.02.037

PMCID:: PMC10265746

Abstract Article PDF–3.3M

Select item 101066306.

Epigenetic control of CD1D expression as a mechanism of resistance to immune checkpoint therapy in poorly immunogenic melanomas

Mona Meng Wang, Saara A. Koskela, Arfa Mehmood, Miriam Langguth, Eleftheria Maranou, Carlos R. Figueiredo

Front Immunol. 2023; 14: 1152228. Published online 2023 Apr 3. doi: 10.3389/fimmu.2023.1152228

PMCID:: PMC10106630

Abstract Article PDF–4.2M

Select item 94029937.

Thymic epithelial cells require lipid kinase Vps34 for CD4 but not CD8 T cell selection

J. Luke Postoak, Wenqiang Song, Guan Yang, Xingyi Guo, Shiyun Xiao, Cherie E. Saffold, Jianhua Zhang, Sebastian Joyce, Nancy R. Manley, Lan Wu, Luc Van Kaer

J Exp Med. 2022 Oct 3; 219(10): e20212554. Published online 2022 Aug 23. doi: 10.1084/jem.20212554

PMCID:: PMC9402993

Abstract Article PDF–6.9M

Select item 89915648.

Steroid-mediated liver steatosis is CD1d-dependent, while steroid-induced liver necrosis, inflammation, and metabolic changes are CD1d-independent

Tomer Adar, Ami Ben Ya’acov, Yehudit Shabat, Meir Mizrahi, Lida Zolotarov, Yoav Lichtenstein, Yaron Ilan

BMC Gastroenterol. 2022; 22: 169. Published online 2022 Apr 7. doi: 10.1186/s12876-022-02242-9

PMCID:: PMC8991564

Abstract Article PDF–5.3M

Select item 89340339.

Stimulation of a subset of natural killer T cells by CD103⁺ DC is required for GM-CSF and protection from pneumococcal infection

Mallory Paynich Murray, Catherine M. Crosby, Paola Marcovecchio, Nadine Hartmann, Shilpi Chandra, Meng Zhao, Archana Khurana, Sonja P. Zahner, Björn E. Clausen, Fadie T. Coleman, Joseph P. Mizgerd, Zbigniew Mikulski, Mitchell Kronenberg

Cell Rep. Author manuscript; available in PMC 2022 Mar 19.

Published in final edited form as: Cell Rep. 2022 Jan 11; 38(2): 110209. doi: 10.1016/j.celrep.2021.110209

PMCID:: PMC8934033

Abstract Article PDF–1.6M

Select item 885651110.

The lysophospholipid-binding molecule CD1D is not required for the alloimmunization response to fresh or stored RBCs in mice despite RBC storage driving alterations in lysophospholipids

Jelena Medved, Brittney M. Knott, Soraya N. Tarrah, Andria N. Li, Neha Shah, Tamara C. Moscovich, Alexis R. Boscia, Juan E. Salazar, Manjula Santhanakrishnan, Jeanne E. Hendrickson, Xiaoyun Fu, James C. Zimring, Chance John Luckey

Transfusion. Author manuscript; available in PMC 2022 Jul 1.

Published in final edited form as: Transfusion. 2021 Jul; 61(7): 2169–2178. Published online 2021 Jun 28. doi: 10.1111/trf.16554

PMCID:: PMC8856511

Abstract Article PDF–1.0M

Select item 865503911.

Modulation of TCR signalling components occurs prior to positive selection and lineage commitment in iNKT cells

Xuyen T. Dinh, Dragana Stanley, Letitia D. Smith, Morgane Moreau, Stuart P. Berzins, Adrian Gemiarto, Alan G. Baxter, Margaret A. Jordan

Sci Rep. 2021; 11: 23650. Published online 2021 Dec 8. doi: 10.1038/s41598-021-02885-w

PMCID:: PMC8655039

Abstract Article PDF–5.4M

Select item 861298712.

Thymus-derived CD4⁺CD8⁺ cells reside in mediastinal adipose tissue and the aortic arch

Holger Winkels, Yanal Ghosheh, Kouji Kobiyama, William B. Kiosses, Marco Orecchioni, Erik Ehinger, Vasantika Suryawanshi, Sara Herrera-De La Mata, Paola Marchovecchio, Thomas Riffelmacher, Nicolas Thiault, Mitchell Kronenberg, Dennis Wolf, Gregory Seumois, Pandurangan Vijayanand, Klaus Ley

J Immunol. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: J Immunol. 2021 Dec 1; 207(11): 2720–2732. Published online 2021 Nov 5. doi: 10.4049/jimmunol.2100208

PMCID:: PMC8612987

Abstract Article PDF–2.7M

Select item 852696513.

Activation of iNKT Cells Facilitates Liver Repair After Hepatic Ischemia Reperfusion Injury Through Acceleration of Macrophage Polarization

Takuya Goto, Yoshiya Ito, Masashi Satoh, Shuji Nakamoto, Nobuyuki Nishizawa, Kanako Hosono, Takeshi Naitoh, Koji Eshima, Kazuya Iwabuchi, Naoki Hiki, Hideki Amano

Front Immunol. 2021; 12: 754106. Published online 2021 Oct 6. doi: 10.3389/fimmu.2021.754106

PMCID:: PMC8526965

Abstract Article PDF–17M

Select item 823478714.

Distinct iNKT cell populations use IFNγ or ER stress-induced IL-10 to control adipose tissue homeostasis

Nelson M. LaMarche, Harry Kane, Ayano C. Kohlgruber, Han Dong, Lydia Lynch, Michael B. Brenner

Cell Metab. Author manuscript; available in PMC 2021 Aug 4.

Published in final edited form as: Cell Metab. 2020 Aug 4; 32(2): 243–258.e6. Published online 2020 Jun 8. doi: 10.1016/j.cmet.2020.05.017

PMCID:: PMC8234787

Abstract Article PDF–2.7M

Select item 813752915.

Serial Stimulation of Invariant Natural Killer T Cells with Covalently Stabilized Bispecific T Cell Engagers Generates Anti-Tumor Immunity While Avoiding Anergy

Shalu Sharma Kharkwal, Christopher T. Johndrow, Natacha Veerapen, Himanshu Kharkwal, Noemi A. Saavedra-Avila, Leandro J. Carreño, Samantha Rothberg, Jinghang Zhang, Scott J. Garforth, Peter J. Jervis, Lianjun Zhang, Alena Donda, Amareeta K. Besra, Liam R. Cox, Steven C. Almo, Alan Howell, Elizabeth E. Evans, Maurice Zauderer, Gurdyal S. Besra, Steven A. Porcelli

Cancer Res. Author manuscript; available in PMC 2021 Oct 1.

Published in final edited form as: Cancer Res. 2021 Apr 1; 81(7): 1788–1801. Published online 2021 Jan 22. doi: 10.1158/0008-5472.CAN-20-2219

PMCID:: PMC8137529

Abstract Article PDF–2.9M

Select item 809394216.

CD1d deficiency limits tolerogenic properties of peritoneal macrophages

Fathihah Basri, Sundo Jung, Se Hoon Park, Se-Ho Park

BMB Rep. 2021 Apr 30; 54(4): 209–214. Published online 2021 Apr 30. doi: 10.5483/BMBRep.2021.54.4.183

PMCID:: PMC8093942

Abstract Article PDF–3.3M

Select item 788464617.

Hepatocyte CD1d protects against liver immunopathology in mice with schistosomiasis japonica

Zhigang Lei, Rui Tang, Qianqian Qi, Pan Gu, Junling Wang, Lei Xu, Chuan Wei, Yanan Pu, Xin Qi, Ying Chen, Beibei Yu, Yanxiong Yu, Xiaojun Chen, Jifeng Zhu, Yalin Li, Sha Zhou, Chuan Su

Immunology. 2021 Mar; 162(3): 328–338. Published online 2020 Dec 22. doi: 10.1111/imm.13288

PMCID:: PMC7884646

Abstract Article PDF–1.5M

Select item 757771818.

CD1d1 intrinsic signaling in macrophages controls NLRP3 inflammasome expression during inflammation

Shan Cui, Chenhui Wang, Weizhi Bai, Jiao Li, Yue Pan, Xiaoyong Huang, Han Yang, Zeqing Feng, Qun Xiang, Lei Fei, Lixin Zheng, Jian Huang, Qinggao Zhang, Yuzhang Wu, Yongwen Chen

Sci Adv. 2020 Oct; 6(43): eaaz7290. Published online 2020 Oct 21. doi: 10.1126/sciadv.aaz7290

PMCID:: PMC7577718

Abstract Article PDF–6.9M

Select item 734757219.

Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues

Dominika W. Gajdasik, Fabrina Gaspal, Emily E. Halford, Remi Fiancette, Emma E. Dutton, Claire Willis, Timo Rückert, Chiara Romagnani, Audrey Gerard, Sarah L. Bevington, Andrew S. MacDonald, Marina Botto, Timothy Vyse, David R. Withers

Nat Commun. 2020; 11: 3421. Published online 2020 Jul 9. doi: 10.1038/s41467-020-17293-3

PMCID:: PMC7347572

Abstract Article PDF–2.6M

Select item 719850020.

Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells

Beth Lucas, Andrea J. White, Emilie J. Cosway, Sonia M. Parnell, Kieran D. James, Nick D. Jones, Izumi Ohigashi, Yousuke Takahama, William E. Jenkinson, Graham Anderson

Nat Commun. 2020; 11: 2198. Published online 2020 May 4. doi: 10.1038/s41467-020-16041-x

PMCID:: PMC7198500

Abstract Article PDF–3.3M

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