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Items: 1 to 20 of 674

1.
SARS-CoV-2 ORF3a induces COVID-19-associated kidney injury through HMGB1-mediated cytokine production
Chenyu Zhang, Volodymyr Gerzanich, Ruth Cruz-Cosme, Jiantao Zhang, Orest Tsymbalyuk, Cigdem Tosun, Bhargava Teja Sallapalli, Dongxiao Liu, Kaspar Keledjian, John C. Papadimitriou, Cinthia B. Drachenberg, Mohamed Nasr, Yanjin Zhang, Qiyi Tang, J. Marc Simard, Richard Y. Zhao
mBio. 2024 Nov; 15(11): e02308-24. Published online 2024 Sep 30. doi: 10.1128/mbio.02308-24
PMCID:
PMC11559048
AbstractArticlePDF–3.3M
2.
IFN-γ induces acute graft-versus-host disease by promoting HMGB1-mediated nuclear-to-cytoplasm translocation and autophagic degradation of p53
Shiyu Wang, Tingting Cheng, Xu Chen, Cong Zeng, Wei Qin, Yajing Xu
Clin Sci (Lond) 2024 Oct; 138(20): 1287–1304. Published online 2024 Oct 11. doi: 10.1042/CS20241144
PMCID:
PMC11479981
AbstractArticlePDF–9.1M
3.
Elevated levels of damage-associated molecular patterns HMGB1 and S100A8/A9 coupled with toll-like receptor-triggered monocyte activation are associated with inflammation in patients with myelofibrosis
Geraldine De Luca, Nora P. Goette, Paola R. Lev, Maria C. Baroni Pietto, Cecilia P. Marin Oyarzún, Miguel A. Castro Ríos, Beatriz Moiraghi, Federico Sackmann, Laureano J. Kamiya, Veronica Verri, Victoria Caula, Vanina Fernandez, Angeles Vicente, Julio Pose Cabarcos, Vanesa Caruso, Maria F. Camacho, Irene B. Larripa, Marina Khoury, Rosana F. Marta, Ana C. Glembotsky, Paula G. Heller
Front Immunol. 2024; 15: 1365015. Published online 2024 Sep 25. doi: 10.3389/fimmu.2024.1365015
PMCID:
PMC11465240
AbstractArticlePDF–3.0M
4.
S100A9 and HMGB1 orchestrate MDSC-mediated immunosuppression in melanoma through TLR4 signaling
Feyza Gül Özbay Kurt, Beatrice-Ana Cicortas, Bianca M Balzasch, Carolina De la Torre, Volker Ast, Ece Tavukcuoglu, Cagla Ak, Sebastian A Wohlfeil, Adelheid Cerwenka, Jochen Utikal, Viktor Umansky
J Immunother Cancer. 2024; 12(8): e009552. Published online 2024 Aug 19. doi: 10.1136/jitc-2024-009552
PMCID:
PMC11409250
AbstractArticlePDF–2.5M
5.
LncRNA ILF3‐AS1 mediates oxidative stress and inflammation through miR‐504‐3p/HMGB1 axis in a cellular model of temporal lobe epilepsy
Peipei Gao, Ying Wu, Zhixin Yan
Brain Behav. 2024 Aug; 14(8): e3615. Published online 2024 Aug 12. doi: 10.1002/brb3.3615
PMCID:
PMC11319232
AbstractArticlePDF–2.6M
6.
A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex
Marisa Bedir, Emily Outwin, Rita Colnaghi, Lydia Bassett, Iga Abramowicz, Mark O’Driscoll
EMBO Rep. 2024 Aug; 25(8): 3432–3455. Published online 2024 Jun 28. doi: 10.1038/s44319-024-00184-9
PMCID:
PMC11315929
AbstractArticlePDF–3.4M
7.
DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples
Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang
J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.
Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832
PMCID:
PMC11296914
AbstractArticlePDF–1.7M
8.
HMGB1-Mediated Cell Death—A Crucial Element in Post-Hepatectomy Liver Failure
Laura Brunnthaler, Thomas G. Hammond, David Pereyra, Jonas Santol, Joel Probst, Valerie Laferl, Ulrike Resch, Monika Aiad, Anna Sofie Janoschek, Thomas Gruenberger, Hubert Hackl, Patrick Starlinger, Alice Assinger
Int J Mol Sci. 2024 Jul; 25(13): 7150. Published online 2024 Jun 28. doi: 10.3390/ijms25137150
PMCID:
PMC11241647
AbstractArticlePDF–4.3M
9.
Effects of High-Mobility Group Box-1 on Mucosal Immunity and Epithelial Differentiation in Colitic Carcinoma
Takamitsu Sasaki, Rina Fujiwara-Tani, Yi Luo, Ruiko Ogata, Rika Sasaki, Ayaka Ikemoto, Yukiko Nishiguchi, Chie Nakashima, Shingo Kishi, Kiyomu Fujii, Hitoshi Ohmori, Naohide Oue, Hiroki Kuniyasu
Int J Mol Sci. 2024 Jul; 25(13): 6846. Published online 2024 Jun 21. doi: 10.3390/ijms25136846
PMCID:
PMC11241214
AbstractArticlePDF–8.6M
10.
CircUBE2D2 regulates HMGB1 through miR-885-5p to promote ovarian cancer malignancy
RuiXue Yan, SaiTian Zeng, FangYuan Gao, LingLing Li, XiYun Xiao
Clinics (Sao Paulo) 2024 Jan-Dec; 79: 100391. Published online 2024 Jun 6. doi: 10.1016/j.clinsp.2024.100391
PMCID:
PMC11214364
AbstractArticlePDF–3.2M
11.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
12.
Tumor cells express and maintain HMGB1 in the reduced isoform to enhance CXCR4-mediated migration
Edisa Pirani, Philipp Paparoditis, Matteo Pecoraro, Gabriela Danelon, Marcus Thelen, Valentina Cecchinato, Mariagrazia Uguccioni
Front Immunol. 2024; 15: 1358800. Published online 2024 May 13. doi: 10.3389/fimmu.2024.1358800
PMCID:
PMC11128625
AbstractArticlePDF–2.9M
13.
CHIP induces ubiquitination and degradation of HMGB1 to regulate glycolysis in ovarian endometriosis
Yujun Sun, Qian Wang, Mengxue Wang, Fangyuan Sun, Pengyun Qiao, Aifang Jiang, Chune Ren, Zhenhai Yu, Tingting Yang
Cell Mol Life Sci. 2023 Jan; 80(1): 13. Published online 2022 Dec 19. doi: 10.1007/s00018-022-04637-z
Correction in:
Cell Mol Life Sci. 2023 Apr; 80(4): 94.
PMCID:
PMC11073454
AbstractArticlePDF–13M
14.
Targeting BMAL1 reverses drug resistance of acute myeloid leukemia cells and promotes ferroptosis through HMGB1-GPX4 signaling pathway
Hong Zheng, Ting Wu, Zhi Lin, Dan Wang, Jing Zhang, Ting Zeng, Leping Liu, Jie Shen, Mingyi Zhao, Jia-Da Li, Minghua Yang
J Cancer Res Clin Oncol. 2024; 150(5): 231. Published online 2024 May 4. doi: 10.1007/s00432-024-05753-y
PMCID:
PMC11069489
AbstractArticlePDF–12M
15.
Insight into the Interplay of Gd-IgA1, HMGB1, RAGE and PCDH1 in IgA Vasculitis (IgAV)
Martina Held, Ana Kozmar, Mario Sestan, Daniel Turudic, Nastasia Kifer, Sasa Srsen, Alenka Gagro, Marijan Frkovic, Marija Jelusic
Int J Mol Sci. 2024 Apr; 25(8): 4383. Published online 2024 Apr 16. doi: 10.3390/ijms25084383
PMCID:
PMC11050592
AbstractArticlePDF–528K
16.
Cytosolic high-mobility group box protein 1 (HMGB1) and/or PD-1+ TILs in the tumor microenvironment may be contributing prognostic biomarkers for patients with locally advanced rectal cancer who have undergone neoadjuvant chemoradiotherapy
Chih-Yang Huang, Shu-Fen Chiang, Tao-Wei Ke, Tsung-Wei Chen, Yu-Ching Lan, Ying-Shu You, An-Cheng Shiau, William Tzu-Liang Chen, K. S. Clifford Chao
Cancer Immunol Immunother. 2018 Apr; 67(4): 551–562. Published online 2017 Dec 21. doi: 10.1007/s00262-017-2109-5
PMCID:
PMC11028045
AbstractArticlePDF–2.7M
17.
HMGB1 prefers to interact with structural RNAs and regulates rRNA methylation modification and translation in HeLa cells
Meimei Liao, Jiarui Cao, Wen Chen, Mengwei Wang, Zhihui Jin, Jia Ye, Yijun Ren, Yaxun Wei, Yaqiang Xue, Dong Chen, Yi Zhang, Sen Chen
BMC Genomics. 2024; 25: 345. Published online 2024 Apr 5. doi: 10.1186/s12864-024-10204-6
PMCID:
PMC10996203
AbstractArticlePDF–4.4M
18.
Overexpression of HMGB1 in hepatocytes accelerates PTEN inactivation-induced liver cancer
Dipti Athavale, Inés Barahona, Zhuolun Song, Romain Desert, Wei Chen, Hui Han, Sukanta Das, Xiaodong Ge, Sai Santosh B. Komakula, Shenglan Gao, Daniel Lantvit, Grace Guzman, Natalia Nieto
Hepatol Commun. 2023 Dec; 7(12): e0311. Published online 2023 Dec 7. doi: 10.1097/HC9.0000000000000311
PMCID:
PMC10984663
AbstractArticlePDF–1.8M
19.
High-mobility group box 1 increases platelet surface P2Y12 and platelet activation in sickle cell disease
Deirdre Nolfi-Donegan, Gowtham K. Annarapu, Claudette St. Croix, Michael Calderon, Cheryl A. Hillery, Sruti Shiva
JCI Insight. 2024 Mar 8; 9(5): e174575. Published online 2024 Mar 8. doi: 10.1172/jci.insight.174575
PMCID:
PMC10972595
AbstractArticlePDF–1.9M
20.
The Effect of HMGB1 and HMGB2 on Transcriptional Regulation Differs in Neuroendocrine and Adenocarcinoma Models of Prostate Cancer
Martín Salamini-Montemurri, Ángel Vizoso-Vázquez, Aida Barreiro-Alonso, Lidia Lorenzo-Catoira, Esther Rodríguez-Belmonte, María-Esperanza Cerdán, Mónica Lamas-Maceiras
Int J Mol Sci. 2024 Mar; 25(6): 3106. Published online 2024 Mar 7. doi: 10.3390/ijms25063106
PMCID:
PMC10969884
AbstractArticlePDF–3.6M

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