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Items: 1 to 20 of 27

1.
CST–Polymeraseα-primase solves a second telomere end-replication problem
Hiroyuki Takai, Valentina Aria, Pamela Borges, Joseph T. P. Yeeles, Titia de Lange
Nature. Author manuscript; available in PMC 2024 Jun 7.
Published in final edited form as: Nature. 2024 Mar; 627(8004): 664–670. Published online 2024 Feb 28. doi: 10.1038/s41586-024-07137-1
PMCID:
PMC11160940
AbstractArticlePDF–2.4M
2.
Structures of the human CST-Polα–primase complex bound to telomere templates
Qixiang He, Xiuhua Lin, Bianca L. Chavez, Sourav Agrawal, Benjamin L. Lusk, Ci Ji Lim
Nature. Author manuscript; available in PMC 2023 Jun 15.
Published in final edited form as: Nature. 2022 Aug; 608(7924): 826–832. Published online 2022 Jul 13. doi: 10.1038/s41586-022-05040-1
PMCID:
PMC10268231
AbstractArticlePDF–6.4M
3.
Reconstitution of a telomeric replicon organized by CST
Arthur J. Zaug, Karen J. Goodrich, Jessica J. Song, Ashley E. Sullivan, Thomas R. Cech
Nature. 2022; 608(7924): 819–825. Published online 2022 Jul 13. doi: 10.1038/s41586-022-04930-8
PMCID:
PMC9402439
AbstractArticlePDF–29M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
CST in maintaining genome stability: beyond telomeres
Xinxing Lyu, Pau Biak Sang, Weihang Chai
DNA Repair (Amst) Author manuscript; available in PMC 2022 Jun 1.
Published in final edited form as: DNA Repair (Amst). 2021 Jun; 102: 103104. Published online 2021 Mar 22. doi: 10.1016/j.dnarep.2021.103104
PMCID:
PMC8081025
AbstractArticlePDF–903K
6.
Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent‐strand DNA
Xinxing Lyu, Kai‐Hang Lei, Pau Biak Sang, Olga Shiva, Megan Chastain, Peter Chi, Weihang Chai
EMBO J. 2021 Jan 15; 40(2): e103654. Published online 2020 Nov 19. doi: 10.15252/embj.2019103654
PMCID:
PMC7809791
AbstractArticlePDF–4.5M
7.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117
PMCID:
PMC7322067
AbstractArticlePDF–2.7M
8.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
9.
Mammalian CST averts replication failure by preventing G-quadruplex accumulation
Miaomiao Zhang, Bing Wang, Tingfang Li, Rui Liu, Yingnan Xiao, Xin Geng, Guang Li, Qiang Liu, Carolyn M Price, Yang Liu, Feng Wang
Nucleic Acids Res. 2019 Jun 4; 47(10): 5243–5259. Published online 2019 Apr 12. doi: 10.1093/nar/gkz264
PMCID:
PMC6547417
AbstractArticlePDF–6.9M
10.
Structural and functional impact of non-synonymous SNPs in the CST complex subunit TEN1: structural genomics approach
Mohd. Amir, Vijay Kumar, Taj Mohammad, Ravins Dohare, Md. Tabish Rehman, Mohamed F. Alajmi, Afzal Hussain, Faizan Ahmad, Md. Imtaiyaz Hassan
Biosci Rep. 2019 May 31; 39(5): BSR20190312. Prepublished online 2019 Apr 26. Published online 2019 May 15. doi: 10.1042/BSR20190312
PMCID:
PMC6522806
AbstractArticlePDF–1.8M
11.
Human CST suppresses origin licensing and promotes AND-1/Ctf4 chromatin association
Yilin Wang, Kathryn S Brady, Benjamin P Caiello, Stephanie M Ackerson, Jason A Stewart
Life Sci Alliance. 2019 Apr; 2(2): e201800270. Published online 2019 Apr 12. doi: 10.26508/lsa.201800270
PMCID:
PMC6464128
AbstractArticlePDF–2.5M
12.
Emerging roles of CST in maintaining genome stability and human disease
Jason A. Stewart, Yilin Wang, Stephanie M. Ackerson, P. Logan Schuck
Front Biosci (Landmark Ed) Author manuscript; available in PMC 2018 Dec 28.
Published in final edited form as: Front Biosci (Landmark Ed). 2018 Mar 1; 23: 1564–1586. Published online 2018 Mar 1. doi: 10.2741/4661
PMCID:
PMC6309963
AbstractArticlePDF–1.2M
13.
CTC1-STN1 terminates telomerase while STN1-TEN1 enables C-strand synthesis during telomere replication in colon cancer cells
Xuyang Feng, Shih-Jui Hsu, Anukana Bhattacharjee, Yongyao Wang, Jiajie Diao, Carolyn M. Price
Nat Commun. 2018; 9: 2827. Published online 2018 Jul 19. doi: 10.1038/s41467-018-05154-z
PMCID:
PMC6053418
AbstractArticlePDF–1.4M
14.
The human CTC1/STN1/TEN1 complex regulates telomere maintenance in ALT cancer cells
Chenhui Huang, Pingping Jia, Megan Chastain, Olga Shiva, Weihang Chai
Exp Cell Res. Author manuscript; available in PMC 2017 Aug 10.
Published in final edited form as: Exp Cell Res. 2017 Jun 15; 355(2): 95–104. Published online 2017 Mar 31. doi: 10.1016/j.yexcr.2017.03.058
PMCID:
PMC5551977
AbstractArticlePDF–1.6M
15.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
16.
CTC1-mediated C-strand fill-in is an essential step in telomere length maintenance
Xuyang Feng, Shih-Jui Hsu, Christopher Kasbek, Mary Chaiken, Carolyn M. Price
Nucleic Acids Res. 2017 May 5; 45(8): 4281–4293. Published online 2017 Feb 23. doi: 10.1093/nar/gkx125
PMCID:
PMC5416890
AbstractArticlePDF–3.5M
17.
Human CST facilitates genome-wide RAD51 recruitment to GC-rich repetitive sequences in response to replication stress
Megan Chastain, Qing Zhou, Olga Shiva, Leanne Whitmore, Pingping Jia, Xueyu Dai, Chenhui Huang, Maria Fadri-Moskwik, Ping Ye, Weihang Chai
Cell Rep. Author manuscript; available in PMC 2017 Aug 2.
Published in final edited form as: Cell Rep. 2016 Aug 2; 16(5): 1300–1314. doi: 10.1016/j.celrep.2016.06.077
Correction in:
Cell Rep. 2016 Aug 16; 16(7): 2048.
PMCID:
PMC4976776
AbstractArticlePDF–2.3M
18.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
19.
Stn1 is critical for telomere maintenance and long-term viability of somatic human cells
Virginia Boccardi, Neetu Razdan, Jessica Kaplunov, Jyoti J Mundra, Masayuki Kimura, Abraham Aviv, Utz Herbig
Aging Cell. 2015 Jun; 14(3): 372–381. Published online 2015 Feb 14. doi: 10.1111/acel.12289
PMCID:
PMC4406666
AbstractArticlePDF–902K
20.
CST for the grand finale of telomere replication
Liuh-Yow Chen, Joachim Lingner
Nucleus. 2013 Jul 1; 4(4): 277–282. Published online 2013 Jul 10. doi: 10.4161/nucl.25701
PMCID:
PMC3810335
AbstractArticlePDF–1.2M

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