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Select item 115060591.

N6-Methyladenosine Methyltransferase Component KIAA1429 Is a Potential Target of Cancer Therapy

Junjun Huang, Jihua Guo, Rong Jia

Biomolecules. 2024 Oct; 14(10): 1319. Published online 2024 Oct 17. doi: 10.3390/biom14101319

PMCID:: PMC11506059

Abstract Article PDF–1.3M

Select item 114968572.

Role and mechanism of KIAA1429 in regulating cellular ferroptosis and radioresistance in colorectal cancer

Hao Chen, Peipei Zhu, Dan Zhu, Juan Jin, Qianni Yang, Xiaodong Han

Biomol Biomed. 2024 Dec 1; 24(6): 1669–1681. Published online 2024 Dec 1. doi: 10.17305/bb.2024.10313

PMCID:: PMC11496857

Abstract Article PDF–4.6M

Select item 113790213.

VIRMA promotes the progression of head and neck squamous cell carcinoma by regulating UBR5 mRNA and m6A levels

Chunyu Zhu, Yameng Cheng, Yao Yu, Yanning Zhang, Guiyun Ren

Biomol Biomed. 2024 Oct 1; 24(5): 1244–1257. Published online 2024 Oct 1. doi: 10.17305/bb.2024.10358

PMCID:: PMC11379021

Abstract Article PDF–6.1M

Select item 112821414.

KIAA1429 increases FOXM1 expression through YTHDF1–mediated m6A modification to promote aerobic glycolysis and tumorigenesis in multiple myeloma

Yue Wu, Yi Luo, Xingchen Yao, Xiangjun Shi, Ziyu Xu, Jie Re, Ming Shi, Meng Li, Junpeng Liu, Youzhi He, Xinru Du

Cell Biol Toxicol. 2024; 40(1): 58. Published online 2024 Jul 26. doi: 10.1007/s10565-024-09904-2

PMCID:: PMC11282141

Abstract Article PDF–9.3M

Select item 112099355.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 111941236.

KIAA1429 regulates lung adenocarcinoma proliferation and metastasis through the PI3K/AKT pathway by modulating ARHGAP30 expression

Wei Guo, Tan Wang, Qilin Huai, Lei Guo, Xiaobing Wang, Jie He

Thorac Cancer. 2024 Jun; 15(18): 1397–1409. Published online 2024 May 8. doi: 10.1111/1759-7714.15327

PMCID:: PMC11194123

Abstract Article PDF–9.1M

Select item 107469547.

KIAA1429 protects hepatocellular carcinoma cells from ferroptotic cell death with a m⁶A‐dependent posttranscriptional modification of SLC7A11

Houhong Wang, Wenli Chen, Yayun Cui, Huihui Gong, Heng Li

J Cell Mol Med. 2023 Dec; 27(24): 4118–4132. Published online 2023 Oct 13. doi: 10.1111/jcmm.17997

PMCID:: PMC10746954

Abstract Article PDF–36M

Select item 105658768.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 105614809.

N6-methyladenosine methyltransferase KIAA1429 promoted ovarian cancer aerobic glycolysis and progression through enhancing ENO1 expression

Lijuan Gan, Shengchao Zhao, Yang Gao, Yuwen Qi, Min Su, Anjin Wang, Hongbing Cai

Biol Direct. 2023; 18: 64. Published online 2023 Oct 9. doi: 10.1186/s13062-023-00420-7

PMCID:: PMC10561480

Abstract Article PDF–14M

Select item 1053792310.

CRISPR-Cas9 knockout screening identifies KIAA1429 as an essential gene in Ewing sarcoma

Kezhe Tan, Wenjie Lu, Feng Chen, Hao Shi, Yingxuan Ma, Zhou Chen, Wei Wu, Zhibao Lv, Jialin Mo

J Exp Clin Cancer Res. 2023; 42: 250. Published online 2023 Sep 28. doi: 10.1186/s13046-023-02828-5

PMCID:: PMC10537923

Abstract Article PDF–3.6M

Select item 1052238611.

Pan-cancer analysis and experimental validation revealed the m6A methyltransferase KIAA1429 as a potential biomarker for diagnosis, prognosis, and immunotherapy

Chao Ma, Qiming Zheng, Yepeng Wang, Guoxiang Li, Mengmeng Zhao, Zhigang Sun

Aging (Albany NY) 2023 Sep 15; 15(17): 8664–8691. Published online 2023 Aug 21. doi: 10.18632/aging.204968

PMCID:: PMC10522386

Abstract Article PDF–8.0M

Select item 1023742212.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1023543713.

VIRMA promotes nasopharyngeal carcinoma, tumorigenesis, and metastasis by upregulation of E2F7 in an m6A-dependent manner

Zi-Qi Zheng, Zhuo-Hui Huang, Ye-Lin Liang, Wei-Hong Zheng, Cheng Xu, Zhi-Xuan Li, Na Liu, Pan-Yang Yang, Ying-Qin Li, Jun Ma, Ying Sun, Ling-Long Tang, Denghui Wei

J Biol Chem. 2023 May; 299(5): 104677. Published online 2023 Apr 5. doi: 10.1016/j.jbc.2023.104677

PMCID:: PMC10235437

Abstract Article PDF–6.9M

Select item 1017144014.

Promotive role of USP29-mediated deubiquitination in malignant proliferation of colorectal cancer cells via the KIAA1429/SOX8 axis

Juncai Li, Jianguo Yang, Zhenzhou Chen, Li Liu, Hao Wang, Qican Deng, Yajun Chen, Yong Que, Zhongxue Fu

Biomol Biomed. 2023 Jun 1; 23(3): 483–495. Published online 2023 May 1. doi: 10.17305/bjbms.2022.7930

PMCID:: PMC10171440

Abstract Article PDF–4.9M

Select item 1006709315.

KIAA1429 mediates epithelial mesenchymal transition in sorafenib‐resistant hepatocellular carcinoma through m6A methylation modification

Ye Kuang, Yun Cheng, Jia Wang, Hongyan Li, Xianghong Cao, Yang Wang

Cancer Med. 2023 Mar; 12(6): 7222–7233. Published online 2022 Nov 24. doi: 10.1002/cam4.5432

PMCID:: PMC10067093

Abstract Article PDF–2.5M

Select item 995044716.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x