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Select item 107670931.

Targeting NEDD8 suppresses surgical stress-facilitated metastasis of colon cancer via restraining regulatory T cells

Yi Jiang, Shenjia Gao, Hao Sun, Xinyi Wu, Jiahui Gu, Han Wu, Yun Liao, Ronen Ben-Ami, Changhong Miao, Rong Shen, Jinlong Liu, Wankun Chen

Cell Death Dis. 2024 Jan; 15(1): 8. Published online 2024 Jan 5. doi: 10.1038/s41419-023-06396-6

PMCID:: PMC10767093

Abstract Article PDF–12M

Select item 87633172.

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation

Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley

Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h

PMCID:: PMC8763317

Abstract Article

Select item 79387703.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 75849164.

Neddylation is critical to cortical development by regulating Wnt/β-catenin signaling

Lei Zhang, Hongyang Jing, Haiwen Li, Wenbing Chen, Bin Luo, Hongsheng Zhang, Zhaoqi Dong, Lei Li, Huabo Su, Wen-Cheng Xiong, Lin Mei

Proc Natl Acad Sci U S A. 2020 Oct 20; 117(42): 26448–26459. Published online 2020 Oct 5. doi: 10.1073/pnas.2005395117

PMCID:: PMC7584916

Abstract Article PDF–3.2M

Select item 69352435.

Interleukin-1β drives NEDD8 nuclear-to-cytoplasmic translocation, fostering parkin activation via NEDD8 binding to the P-ubiquitin activating site

Meenakshisundaram Balasubramaniam, Paul A. Parcon, Chhanda Bose, Ling Liu, Richard A. Jones, Martin R. Farlow, Robert E. Mrak, Steven W. Barger, W. Sue T. Griffin

J Neuroinflammation. 2019; 16: 275. Published online 2019 Dec 27. doi: 10.1186/s12974-019-1669-z

PMCID:: PMC6935243

Abstract Article PDF–6.4M

Select item 65547236.

Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca²⁺/CaM) and CaM Kinase II (CaMKII) Binding Partner

Paul R. Evans, Kyle J. Gerber, Eric B. Dammer, Duc M. Duong, Devrishi Goswami, Daniel J. Lustberg, Juan Zou, Jenny J. Yang, Serena M. Dudek, Patrick R. Griffin, Nicholas T. Seyfried, John R. Hepler

J Proteome Res. Author manuscript; available in PMC 2019 Jun 7.

Published in final edited form as: J Proteome Res. 2018 Apr 6; 17(4): 1700–1711. Published online 2018 Mar 20. doi: 10.1021/acs.jproteome.8b00027

PMCID:: PMC6554723

Abstract Article PDF–2.0M

Select item 59249057.

Neddylation mediates ventricular chamber maturation through repression of Hippo signaling

Jianqiu Zou, Wenxia Ma, Jie Li, Rodney Littlejohn, Hongyi Zhou, Il-man Kim, David J. R. Fulton, Weiqin Chen, Neal L. Weintraub, Jiliang Zhou, Huabo Su

Proc Natl Acad Sci U S A. 2018 Apr 24; 115(17): E4101–E4110. Published online 2018 Apr 9. doi: 10.1073/pnas.1719309115

PMCID:: PMC5924905

Abstract Article PDF–2.3M

Select item 55208818.

Promoting tumorigenesis in nasopharyngeal carcinoma, NEDD8 serves as a potential theranostic target

Ping Xie, Jun-Ping Yang, Yun Cao, Li-Xia Peng, Li-Sheng Zheng, Rui Sun, Dong-Fang Meng, Meng-Yao Wang, Yan Mei, Yuan-Yuan Qiang, Li Cao, Yan-Qun Xiang, Dong-Hua Luo, Jing-Ping Yun, Bi-Jun Huang, Li-Jun Jia, Chao-Nan Qian

Cell Death Dis. 2017 Jun; 8(6): e2834. Published online 2017 Jun 1. doi: 10.1038/cddis.2017.195

PMCID:: PMC5520881

Abstract Article PDF–6.4M

Select item 50699559.

Identification of Novel Host Interactors of Effectors Secreted by Salmonella and Citrobacter

Ryan L. Sontag, Ernesto S. Nakayasu, Roslyn N. Brown, George S. Niemann, Michael A. Sydor, Octavio Sanchez, Charles Ansong, Shao-Yeh Lu, Hyungwon Choi, Dylan Valleau, Karl K. Weitz, Alexei Savchenko, Eric D. Cambronne, Joshua N. Adkins

mSystems. 2016 Jul-Aug; 1(4): e00032-15. Published online 2016 Jul 12. doi: 10.1128/mSystems.00032-15

PMCID:: PMC5069955

Abstract Article PDF–1.1M

Select item 505876910.

NEDL2 regulates enteric nervous system and kidney development in its Nedd8 ligase activity-dependent manner

Xiao Qiu, Rongfei Wei, Yang Li, Qiong Zhu, Cong Xiong, Yuhan Chen, Yuan Zhang, Kefeng Lu, Fuchu He, Lingqiang Zhang

Oncotarget. 2016 May 24; 7(21): 31440–31453. Published online 2016 Apr 23. doi: 10.18632/oncotarget.8951

PMCID:: PMC5058769

Abstract Article PDF–6.4M

Select item 472832211.

Interactions between the otitis media gene, Fbxo11, and p53 in the mouse embryonic lung

Hilda Tateossian, Susan Morse, Michelle M. Simon, Charlotte H. Dean, Steve D. M. Brown

Dis Model Mech. 2015 Dec 1; 8(12): 1531–1542. doi: 10.1242/dmm.022426

PMCID:: PMC4728322

Abstract Article

Select item 433076512.

Src phosphorylation converts Mdm2 from a ubiquitinating to a neddylating E3 ligase

Christopher N. Batuello, Paula M. Hauck, Jaimie M. Gendron, Jason A. Lehman, Lindsey D. Mayo

Proc Natl Acad Sci U S A. 2015 Feb 10; 112(6): 1749–1754. Published online 2015 Jan 26. doi: 10.1073/pnas.1416656112

PMCID:: PMC4330765

Abstract Article PDF–1.1M

Select item 428553813.

Stabilization of HIF through inhibition of Cullin-2 neddylation is protective in mucosal inflammatory responses

Valerie F. Curtis, Stefan F. Ehrentraut, Eric L. Campbell, Louise E. Glover, Amanda Bayless, Caleb J. Kelly, Douglas J. Kominsky, Sean P. Colgan

FASEB J. 2015 Jan; 29(1): 208–215. Published online 2014 Oct 17. doi: 10.1096/fj.14-259663

PMCID:: PMC4285538

Abstract Article

Select item 428542914.

Nedd8 Regulates Inflammasome-Dependent Caspase-1 Activation

Jesus A. Segovia, Su-Yu Tsai, Te-Hung Chang, Niraj K. Shil, Susan T. Weintraub, John D. Short, Santanu Bose

Mol Cell Biol. 2015 Feb; 35(3): 582–597. Prepublished online 2014 Dec 1. Published online 2015 Jan 7. doi: 10.1128/MCB.00775-14

PMCID:: PMC4285429

Abstract Article PDF–2.3M

Select item 360563215.

H₂O₂ Regulates Lung Epithelial Sodium Channel (ENaC) via Ubiquitin-like Protein Nedd8

Charles A. Downs, Amrita Kumar, Lisa H. Kreiner, Nicholle M. Johnson, My N. Helms

J Biol Chem. 2013 Mar 22; 288(12): 8136–8145. Published online 2013 Jan 28. doi: 10.1074/jbc.M112.389536

PMCID:: PMC3605632

Abstract Article PDF–2.6M

Select item 357241016.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 354582517.

Neddylation pathway regulates T-cell function by targeting an adaptor protein Shc and a protein kinase Erk signaling

Hyung-seung Jin, Lujian Liao, Yoon Park, Yun-Cai Liu

Proc Natl Acad Sci U S A. 2013 Jan 8; 110(2): 624–629. Published online 2012 Dec 24. doi: 10.1073/pnas.1213819110

PMCID:: PMC3545825

Abstract Article PDF–1.0M

Select item 348518318.

Covalent NEDD8 Conjugation Increases RCAN1 Protein Stability and Potentiates Its Inhibitory Action on Calcineurin

Eun Hye Noh, Hee Sook Hwang, Hee Sun Hwang, Boram Min, Eunju Im, Kwang Chul Chung

PLoS One. 2012; 7(10): e48315. Published online 2012 Oct 31. doi: 10.1371/journal.pone.0048315

PMCID:: PMC3485183

Abstract Article PDF–1.8M

Select item 317805919.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 311015120.

A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58

Shigetoshi Yokoyama, Yoshiaki Ito, Hiroe Ueno-Kudoh, Hirohito Shimizu, Kenta Uchibe, Sonia Albini, Kazuhiko Mitsuoka, Shigeru Miyaki, Minako Kiso, Akane Nagai, Tomohiro Hikata, Tadahiro Osada, Noritsugu Fukuda, Satoshi Yamashita, Daisuke Harada, Valeria Mezzano, Masataka Kasai, Pier Lorenzo Puri, Yoshihide Hayashizaki, Haruo Okado, Megumi Hashimoto, Hiroshi Asahara

Dev Cell. Author manuscript; available in PMC 2011 Jun 7.

Published in final edited form as: Dev Cell. 2009 Dec; 17(6): 836–848. doi: 10.1016/j.devcel.2009.10.011

PMCID:: PMC3110151

Abstract Article PDF–2.0M

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