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Select item 93142591.

TFEB induces mitochondrial itaconate synthesis to suppress bacterial growth in macrophages

Ev-Marie Schuster, Maximilian W. Epple, Katharina M. Glaser, Michael Mihlan, Kerstin Lucht, Julia A. Zimmermann, Anna Bremser, Aikaterini Polyzou, Nadine Obier, Nina Cabezas-Wallscheid, Eirini Trompouki, Andrea Ballabio, Jörg Vogel, Joerg M. Buescher, Alexander J. Westermann, Angelika S. Rambold

Nat Metab. 2022; 4(7): 856–866. Published online 2022 Jul 21. doi: 10.1038/s42255-022-00605-w

PMCID:: PMC9314259

Abstract Article PDF–11M

Select item 80203672.

Itaconate is an effector of a Rab GTPase cell-autonomous host defense pathway against Salmonella

Meixin Chen, Hui Sun, Maikel Boot, Lin Shao, Shu-Jung Chang, Weiwei Wang, Tukiet T. Lam, Maria Lara-Tejero, E. Hesper Rego, Jorge E. Galán

Science. Author manuscript; available in PMC 2021 Apr 5.

Published in final edited form as: Science. 2020 Jul 24; 369(6502): 450–455. doi: 10.1126/science.aaz1333

PMCID:: PMC8020367

Abstract Article PDF–1.4M

Select item 77721983.

VARP and Rab9 Are Dispensable for the Rab32/BLOC-3 Dependent Salmonella Killing

Arda Balci, Virtu Solano-Collado, Massimiliano Baldassarre, Stefania Spanò

Front Cell Infect Microbiol. 2020; 10: 581024. Published online 2020 Dec 16. doi: 10.3389/fcimb.2020.581024

PMCID:: PMC7772198

Abstract Article PDF–3.5M

Select item 66229794.

An Intrinsic Neural Oscillator in the Degenerating Mouse Retina

Joanna Borowska, Stuart Trenholm, Gautam B. Awatramani

J Neurosci. 2011 Mar 30; 31(13): 5000–5012. doi: 10.1523/JNEUROSCI.5800-10.2011

PMCID:: PMC6622979

Abstract Article PDF–2.9M

Select item 64979445.

The BLOC-3 subunit HPS4 is required for activation of Rab32/38 GTPases in melanogenesis, but its Rab9 activity is dispensable for melanogenesis

Yuta Ohishi, Riko Kinoshita, Soujiro Marubashi, Morié Ishida, Mitsunori Fukuda

J Biol Chem. 2019 Apr 26; 294(17): 6912–6922. Published online 2019 Mar 5. doi: 10.1074/jbc.RA119.007345

PMCID:: PMC6497944

Abstract Article PDF–2.6M

Select item 49703316.

BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriers

Megan K. Dennis, Cédric Delevoye, Amanda Acosta-Ruiz, Ilse Hurbain, Maryse Romao, Geoffrey G. Hesketh, Philip S. Goff, Elena V. Sviderskaya, Dorothy C. Bennett, J. Paul Luzio, Thierry Galli, David J. Owen, Graça Raposo, Michael S. Marks

J Cell Biol. 2016 Aug 1; 214(3): 293–308. doi: 10.1083/jcb.201605090

PMCID:: PMC4970331

Abstract Article PDF–3.7M

Select item 47142257.

RUTBC1 Functions as a GTPase-activating Protein for Rab32/38 and Regulates Melanogenic Enzyme Trafficking in Melanocytes

Soujiro Marubashi, Hikaru Shimada, Mitsunori Fukuda, Norihiko Ohbayashi

J Biol Chem. 2016 Jan 15; 291(3): 1427–1440. Published online 2015 Nov 30. doi: 10.1074/jbc.M115.684043

PMCID:: PMC4714225

Abstract Article PDF–4.5M

Select item 43515078.

Defective release of α granule and lysosome contents from platelets in mouse Hermansky-Pudlak syndrome models

Ronghua Meng, Jie Wu, Dawn C. Harper, Yuhuan Wang, M. Anna Kowalska, Charles S. Abrams, Lawrence F. Brass, Mortimer Poncz, Timothy J. Stalker, Michael S. Marks

Blood. 2015 Mar 5; 125(10): 1623–1632. Prepublished online 2014 Dec 4. doi: 10.1182/blood-2014-07-586727

PMCID:: PMC4351507

Abstract Article

Select item 37864529.

Retinal degeneration increases susceptibility to myopia in mice

Hanna Park, Christopher C. Tan, Amanda Faulkner, Seema B. Jabbar, Gregor Schmid, Jane Abey, P. Michael Iuvone, Machelle T. Pardue

Mol Vis. 2013; 19: 2068–2079. Published online 2013 Sep 28.

PMCID:: PMC3786452

Abstract Article PDF–3.0M

Select item 357241010.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 351337211.

Organelle biogenesis: En BLOC exchange for RAB32 and RAB38

Michael S. Marks

Curr Biol. Author manuscript; available in PMC 2013 Nov 20.

Published in final edited form as: Curr Biol. 2012 Nov 20; 22(22): R963–R965. doi: 10.1016/j.cub.2012.10.005

PMCID:: PMC3513372

Abstract Article PDF–288K

Select item 339875312.

SLC35D3 delivery from megakaryocyte early endosomes is required for platelet dense granule biogenesis and is differentially defective in Hermansky-Pudlak syndrome models

Ronghua Meng, Yuhuan Wang, Yu Yao, Zhe Zhang, Dawn C. Harper, Harry F. G. Heijnen, Anand Sitaram, Wei Li, Graça Raposo, Mitchell J. Weiss, Mortimer Poncz, Michael S. Marks

Blood. 2012 Jul 12; 120(2): 404–414. Prepublished online 2012 May 18. doi: 10.1182/blood-2011-11-389551

PMCID:: PMC3398753

Abstract Article

Select item 323786013.

Separation of Function for Classical and Ganglion Cell Photoreceptors with Respect to Circadian Rhythm Entrainment and Induction of Photosomnolence

L.P. Morin, K.M. Studholme

Neuroscience. Author manuscript; available in PMC 2012 Dec 29.

Published in final edited form as: Neuroscience. 2011 Dec 29; 199: 213–224. Published online 2011 Oct 4. doi: 10.1016/j.neuroscience.2011.09.057

PMCID:: PMC3237860

Abstract Article PDF–1.4M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253415.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 284422316.

Assembly of the Biogenesis of Lysosome-related Organelles Complex-3 (BLOC-3) and Its Interaction with Rab9

Daniel P. Kloer, Raul Rojas, Viorica Ivan, Kengo Moriyama, Thijs van Vlijmen, Namita Murthy, Rodolfo Ghirlando, Peter van der Sluijs, James H. Hurley, Juan S. Bonifacino

J Biol Chem. 2010 Mar 5; 285(10): 7794–7804. Published online 2010 Jan 4. doi: 10.1074/jbc.M109.069088