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Select item 107827221.

Plasma proenkephalin A and incident chronic kidney disease and albuminuria in the REasons for Geographic And Racial Differences in Stroke (REGARDS) cohort

Alexander L. Bullen, Ronit Katz, Sayna Poursadrolah, Samuel A. P. Short, D. Leann Long, Katharine L. Cheung, Shilpa Sharma, Tala Al-Rousan, Alma Fregoso, Janin Schulte, Orlando M. Gutierrez, Michael G. Shlipak, Mary Cushman, Joachim H. Ix, Dena E. Rifkin

BMC Nephrol. 2024; 25: 16. Published online 2024 Jan 10. doi: 10.1186/s12882-023-03432-7

PMCID:: PMC10782722

Abstract Article PDF–1.3M

Select item 107020912.

Proenkephalin as a biomarker correlates with acute kidney injury: a systematic review with meta-analysis and trial sequential analysis

Li-Chun Lin, Min-Hsiang Chuan, Jung-Hua Liu, Hung-Wei Liao, Leong L. Ng, Martin Magnusson, Amra Jujic, Heng-Chih Pan, Vin-Cent Wu, Lui G. Forni

Crit Care. 2023; 27: 481. Published online 2023 Dec 7. doi: 10.1186/s13054-023-04747-5

PMCID:: PMC10702091

Abstract Article PDF–1.4M

Select item 98534793.

Opioid Precursor Gene Expression in the Human Hypothalamus

RENAT R. SUKHOV, LARY C. WALKER, NAOMI E. RANCE, DONALD L. PRICE, W. SCOTT YOUNG, III

J Comp Neurol. Author manuscript; available in PMC 2023 Jan 20.

Published in final edited form as: J Comp Neurol. 1995 Mar 20; 353(4): 604–622. doi: 10.1002/cne.903530410

PMCID:: PMC9853479

Abstract Article PDF–3.1M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 71837095.

PENK inhibits osteosarcoma cell migration by activating the PI3K/Akt signaling pathway

Hai-ping Zhang, Zi-liang Yu, Bing-bing Wu, Fa-rui Sun

J Orthop Surg Res. 2020; 15: 162. Published online 2020 Apr 25. doi: 10.1186/s13018-020-01679-6

PMCID:: PMC7183709

Abstract Article PDF–4.0M

Select item 70982496.

Proenkephalin A Adds No Incremental Prognostic Value After Acute Ischemic Stroke

Philipp Gruber, Felix Fluri, Juliane Schweizer, Andreas Luft, Beat Müller, Mirjam Christ-Crain, Mira Katan

Clin Appl Thromb Hemost. 2020 Jan-Dec; 26: 1076029619895318. Published online 2020 Jan 23. doi: 10.1177/1076029619895318

PMCID:: PMC7098249

Abstract Article PDF–191K

Select item 59795027.

Proinflammatory Markers, Chemokines, and Enkephalin in Patients Suffering from Dry Eye Disease

Pierre Nicolle, Hong Liang, Elodie Reboussin, Ghislaine Rabut, Elise Warcoin, Françoise Brignole-Baudouin, Stéphane Melik-Parsadaniantz, Christophe Baudouin, Antoine Labbe, Annabelle Reaux-Le Goazigo

Int J Mol Sci. 2018 Apr; 19(4): 1221. Published online 2018 Apr 17. doi: 10.3390/ijms19041221

PMCID:: PMC5979502

Abstract Article PDF–3.3M

Select item 55316118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 46868689.

Endogenous opioids contribute to insensitivity to pain in humans and mice lacking sodium channel Na_v1.7

Michael S. Minett, Vanessa Pereira, Shafaq Sikandar, Ayako Matsuyama, Stéphane Lolignier, Alexandros H. Kanellopoulos, Flavia Mancini, Gian D. Iannetti, Yury D. Bogdanov, Sonia Santana-Varela, Queensta Millet, Giorgios Baskozos, Raymond MacAllister, James J. Cox, Jing Zhao, John N. Wood

Nat Commun. 2015; 6: 8967. Published online 2015 Dec 4. doi: 10.1038/ncomms9967

PMCID:: PMC4686868

Abstract Article PDF–860K

Select item 461721110.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 456739411.

Effects of an opioid (proenkephalin) polymorphism on neural response to errors in health and cocaine use disorder

Scott J. Moeller, Nicasia Beebe-Wang, Kristin E. Schneider, Anna B. Konova, Muhammad A. Parvaz, Nelly Alia-Klein, Yasmin L. Hurd, Rita Z. Goldstein

Behav Brain Res. Author manuscript; available in PMC 2016 Oct 15.

Published in final edited form as: Behav Brain Res. 2015 Oct 15; 293: 18–26. Published online 2015 Jul 8. doi: 10.1016/j.bbr.2015.07.004

PMCID:: PMC4567394

Abstract Article PDF–535K

Select item 451786412.

Serum Proenkephalin A Levels and Mortality After Long-Term Follow-Up in Patients with Type 2 Diabetes Mellitus (ZODIAC-32)

Kornelis J. J. van Hateren, Gijs W. D. Landman, Jarinke F. H. Arnold, Hanneke Joosten, Klaas H. Groenier, Gerjan J. Navis, Andrea Sparwasser, Stephan J. L. Bakker, Henk J. G. Bilo, Nanne Kleefstra

PLoS One. 2015; 10(7): e0133065. Published online 2015 Jul 28. doi: 10.1371/journal.pone.0133065

PMCID:: PMC4517864

Abstract Article PDF–588K

Select item 442813113.

Downregulation of the endogenous opioid peptides in the dorsal striatum of human alcoholics

Daniil Sarkisyan, Muhammad Z. Hussain, Hiroyuki Watanabe, Olga Kononenko, Igor Bazov, Xingwu Zhou, Olga Yamskova, Oleg Krishtal, Victor M. Karpyak, Tatiana Yakovleva, Georgy Bakalkin

Front Cell Neurosci. 2015; 9: 187. Published online 2015 May 12. doi: 10.3389/fncel.2015.00187

PMCID:: PMC4428131

Abstract Article PDF–959K

Select item 421948314.

Aberrant methylation of NPY, PENK, and WIF1 as a promising marker for blood-based diagnosis of colorectal cancer

Jean-Pierre Roperch, Roberto Incitti, Solène Forbin, Floriane Bard, Hicham Mansour, Farida Mesli, Isabelle Baumgaertner, Francesco Brunetti, Iradj Sobhani

BMC Cancer. 2013; 13: 566. Published online 2013 Dec 1. doi: 10.1186/1471-2407-13-566

PMCID:: PMC4219483

Abstract Article PDF–600K

Select item 401708915.

Enriched Protein Screening of Human Bone Marrow Mesenchymal Stromal Cell Secretions Reveals MFAP5 and PENK as Novel IL-10 Modulators

Jack M Milwid, Jessica S Elman, Matthew Li, Keyue Shen, Arjun Manrai, Aaron Gabow, Joshua Yarmush, Yunxin Jiao, Anne Fletcher, Jungwoo Lee, Michael J Cima, Martin L Yarmush, Biju Parekkadan

Mol Ther. 2014 May; 22(5): 999–1007. Prepublished online 2014 Feb 5. Published online 2014 Mar 18. doi: 10.1038/mt.2014.17

PMCID:: PMC4017089

Abstract Article PDF–748K

Select item 341935316.

Prefrontal Dopaminergic and Enkephalinergic Synaptic Accommodation in HIV-associated Neurocognitive Disorders and Encephalitis

Benjamin B. Gelman, Joshua G. Lisinicchia, Tianshen Chen, Kenneth M. Johnson, Kristofer Jennings, Daniel H. Freeman, Jr, Vicki M. Soukup

J Neuroimmune Pharmacol. 2012; 7(3): 686–700. Published online 2012 Mar 6. doi: 10.1007/s11481-012-9345-4

PMCID:: PMC3419353

Abstract Article PDF–3.2M

Select item 338218317.

Cannabis-Dependence Risk Relates to Synergism between Neuroticism and Proenkephalin SNPs Associated with Amygdala Gene Expression: Case-Control Study

Didier Jutras-Aswad, Michelle M. Jacobs, Georgia Yiannoulos, Panos Roussos, Panos Bitsios, Yoko Nomura, Xun Liu, Yasmin L. Hurd

PLoS One. 2012; 7(6): e39243. Published online 2012 Jun 22. doi: 10.1371/journal.pone.0039243

PMCID:: PMC3382183

Abstract Article PDF–1.0M

Select item 334610318.

Human Cathepsin V Protease Participates in Production of Enkephalin and NPY Neuropeptide Neurotransmitters

Lydiane Funkelstein, W. Douglas Lu, Britta Koch, Charles Mosier, Thomas Toneff, Laurent Taupenot, Daniel T. O'Connor, Thomas Reinheckel, Christoph Peters, Vivian Hook

J Biol Chem. 2012 May 4; 287(19): 15232–15241. Published online 2012 Mar 5. doi: 10.1074/jbc.M111.310607

PMCID:: PMC3346103

Abstract Article PDF–1.4M

Select item 332834819.

Cortical Opioid Markers in Schizophrenia and across Postnatal Development

David W. Volk, Polina V. Radchenkova, Erin M. Walker, Elizabeth J. Sengupta, David A. Lewis

Cereb Cortex. 2012 May; 22(5): 1215–1223. Published online 2011 Aug 1. doi: 10.1093/cercor/bhr202

PMCID:: PMC3328348

Abstract Article PDF–423K

Select item 332476220.

The prohormone proenkephalin possesses differential conformational features of subdomains revealed by rapid H-D exchange mass spectrometry

Weiya D Lu, Tong Liu, Sheng Li, Virgil L Woods, Vivian Hook

Protein Sci. 2012 Feb; 21(2): 178–187. Published online 2011 Nov 18. doi: 10.1002/pro.2000

PMCID:: PMC3324762

Abstract Article PDF–602K

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