PMC Links for GEO Profiles (Select 84242106) - PMC

Select item 103558061.

Notch3/Hes5 Induces Vascular Dysfunction in Hypoxia-Induced Pulmonary Hypertension Through ER Stress and Redox-Sensitive Pathways

Hannah E. Morris, Karla B. Neves, Margaret Nilsen, Augusto C. Montezano, Margaret R. MacLean, Rhian M. Touyz

Hypertension. 2023 Aug; 80(8): 1683–1696. Published online 2023 May 31. doi: 10.1161/HYPERTENSIONAHA.122.20449

PMCID:: PMC10355806

Abstract Article PDF–2.5M

Select item 80090482.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 71420203.

NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis

Sarah Luiken, Angelika Fraas, Matthias Bieg, Raisatun Sugiyanto, Benjamin Goeppert, Stephan Singer, Carolin Ploeger, Gregor Warsow, Jens U. Marquardt, Carsten Sticht, Carolina De La Torre, Stefan Pusch, Arianeb Mehrabi, Norbert Gretz, Matthias Schlesner, Roland Eils, Peter Schirmacher, Thomas Longerich, Stephanie Roessler

Oncogene. 2020; 39(15): 3128–3144. Published online 2020 Feb 13. doi: 10.1038/s41388-020-1198-3

PMCID:: PMC7142020

Abstract Article PDF–6.9M

Select item 43353794.

HES5 silencing is an early and recurrent change in prostate tumourigenesis

Charles E Massie, Inmaculada Spiteri, Helen Ross-Adams, Hayley Luxton, Jonathan Kay, Hayley C Whitaker, Mark J Dunning, Alastair D Lamb, Antonio Ramos-Montoya, Daniel S Brewer, Colin S Cooper, Rosalind Eeles, UK Prostate ICGC Group, Anne Y Warren, Simon Tavaré, David E Neal, Andy G Lynch

Endocr Relat Cancer. 2015 Apr; 22(2): 131–144. Prepublished online 2015 Jan 5. doi: 10.1530/ERC-14-0454

PMCID:: PMC4335379

Abstract Article PDF–545K

Select item 38174045.

A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities

Franco J Vizeacoumar, Roland Arnold, Frederick S Vizeacoumar, Megha Chandrashekhar, Alla Buzina, Jordan T F Young, Julian H M Kwan, Azin Sayad, Patricia Mero, Steffen Lawo, Hiromasa Tanaka, Kevin R Brown, Anastasia Baryshnikova, Anthony B Mak, Yaroslav Fedyshyn, Yadong Wang, Glauber C Brito, Dahlia Kasimer, Taras Makhnevych, Troy Ketela, Alessandro Datti, Mohan Babu, Andrew Emili, Laurence Pelletier, Jeff Wrana, Zev Wainberg, Philip M Kim, Robert Rottapel, Catherine A O’Brien, Brenda Andrews, Charles Boone, Jason Moffat

Mol Syst Biol. 2013; 9: 696. Published online 2013 Oct 8. doi: 10.1038/msb.2013.54

PMCID:: PMC3817404

Abstract Article PDF–13M

Select item 36790026.

Fbw7 Repression by Hes5 Creates a Feedback Loop That Modulates Notch-Mediated Intestinal and Neural Stem Cell Fate Decisions

Rocio Sancho, Sophia M. Blake, Christian Tendeng, Bruce E. Clurman, Julian Lewis, Axel Behrens

PLoS Biol. 2013 Jun; 11(6): e1001586. Published online 2013 Jun 11. doi: 10.1371/journal.pbio.1001586

PMCID:: PMC3679002

Abstract Article PDF–3.7M

Select item 36373237.

Epigenetic Inactivation of Notch-Hes Pathway in Human B-Cell Acute Lymphoblastic Leukemia

Shao-Qing Kuang, Zhihong Fang, Patrick A. Zweidler-McKay, Hui Yang, Yue Wei, Emilio A. Gonzalez-Cervantes, Yanis Boumber, Guillermo Garcia-Manero

PLoS One. 2013; 8(4): e61807. Published online 2013 Apr 26. doi: 10.1371/journal.pone.0061807

PMCID:: PMC3637323

Abstract Article PDF–3.1M

Select item 32246998.

Notch signaling is required for maintaining stem-cell features of neuroprogenitor cells derived from human embryonic stem cells

Sun-Mi Woo, Janghwan Kim, Hyo-Won Han, Jung-Il Chae, Mi-Young Son, Sunwha Cho, Hyung-Min Chung, Yong-Mahn Han, Yong-Kook Kang

BMC Neurosci. 2009; 10: 97. Published online 2009 Aug 17. doi: 10.1186/1471-2202-10-97

PMCID:: PMC3224699

Abstract Article PDF–1.6M

Select item 31780599.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 287449010.

The expressions of bHLH gene HES1 and HES5 in advanced ovarian serous adenocarcinomas and their prognostic significance: a retrospective clinical study

Xinyu Wang, Yajuan Fu, Xiaoduan Chen, Jing Ye, Bingjian Lü, Feng Ye, Weiguo Lü, Xing Xie

J Cancer Res Clin Oncol. 2010; 136(7): 989–996. Published online 2009 Dec 20. doi: 10.1007/s00432-009-0744-8

PMCID:: PMC2874490

Abstract Article PDF–465K

Select item 278034711.

NOTCH3 SIGNALING IS REQUIRED FOR THE DEVELOPMENT OF PULMONARY ARTERIAL HYPERTENSION

Xiaodong Li, Xiaoxue Zhang, Robin Leathers, Ayako Makino, Chengqun Huang, Pouria Parsa, Jesus Macias, Jason X.-J. Yuan, Stuart W. Jamieson, Patricia A. Thistlethwaite

Nat Med. Author manuscript; available in PMC 2010 May 1.

Published in final edited form as: Nat Med. 2009 Nov; 15(11): 1289–1297. Published online 2009 Oct 25. doi: 10.1038/nm.2021

PMCID:: PMC2780347

Abstract Article PDF–2.1M

Select item 13924112.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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