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Items: 1 to 20 of 23

1.
Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins
Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer
Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490
PMCID:
PMC8266617
AbstractArticlePDF–4.0M
2.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
3.
An Arf/Rab cascade controls the growth and invasiveness of glioblastoma
Gopinath Kulasekaran, Mathilde Chaineau, Valerio Emilio Crescenzo Piscopo, Federica Verginelli, Maryam Fotouhi, Martine Girard, Yeman Tang, Rola Dali, Rita Lo, Stefano Stifani, Peter S. McPherson
J Cell Biol. 2021 Feb 1; 220(2): e202004229. Published online 2021 Jan 14. doi: 10.1083/jcb.202004229
PMCID:
PMC7812876
AbstractArticlePDF–6.2M
4.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
5.
VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu
Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0
PMCID:
PMC5826926
AbstractArticlePDF–2.3M
6.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
7.
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114
PMCID:
PMC5495225
AbstractArticlePDF–1.3M
8.
A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning
Koray Kırlı, Samir Karaca, Heinz Jürgen Dehne, Matthias Samwer, Kuan Ting Pan, Christof Lenz, Henning Urlaub, Dirk Görlich
eLife. 2015; 4: e11466. Published online 2015 Dec 17. doi: 10.7554/eLife.11466
PMCID:
PMC4764573
AbstractArticlePDF–5.7M
9.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
10.
Phosphorylation-dependent Regulation of Connecdenn/DENND1 Guanine Nucleotide Exchange Factors
Gopinath Kulasekaran, Nadya Nossova, Andrea L. Marat, Ingrid Lund, Christopher Cremer, Maria S. Ioannou, Peter S. McPherson
J Biol Chem. 2015 Jul 17; 290(29): 17999–18008. Published online 2015 Jun 8. doi: 10.1074/jbc.M115.636712
PMCID:
PMC4505046
AbstractArticlePDF–1.0M
11.
Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling
Jennifer E. Ho, Wei-Yu Chen, Ming-Huei Chen, Martin G. Larson, Elizabeth L. McCabe, Susan Cheng, Anahita Ghorbani, Erin Coglianese, Valur Emilsson, Andrew D. Johnson, Stefan Walter, Nora Franceschini, Christopher J. O’Donnell, CARDIoGRAM Consortium, CHARGE Inflammation Working Group, Abbas Dehghan, Chen Lu, Daniel Levy, Christopher Newton-Cheh, CHARGE Heart Failure Working Group, Honghuang Lin, Janine F. Felix, Eric R. Schreiter, Ramachandran S. Vasan, James L. Januzzi, Richard T. Lee, Thomas J. Wang
J Clin Invest. 2013 Oct 1; 123(10): 4208–4218. Published online 2013 Sep 3. doi: 10.1172/JCI67119
PMCID:
PMC3784527
AbstractArticlePDF–1.4M
12.
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Luke Jostins, Stephan Ripke, Rinse K Weersma, Richard H Duerr, Dermot P McGovern, Ken Y Hui, James C Lee, L Philip Schumm, Yashoda Sharma, Carl A Anderson, Jonah Essers, Mitja Mitrovic, Kaida Ning, Isabelle Cleynen, Emilie Theatre, Sarah L Spain, Soumya Raychaudhuri, Philippe Goyette, Zhi Wei, Clara Abraham, Jean-Paul Achkar, Tariq Ahmad, Leila Amininejad, Ashwin N Ananthakrishnan, Vibeke Andersen, Jane M Andrews, Leonard Baidoo, Tobias Balschun, Peter A Bampton, Alain Bitton, Gabrielle Boucher, Stephan Brand, Carsten Büning, Ariella Cohain, Sven Cichon, Mauro D’Amato, Dirk De Jong, Kathy L Devaney, Marla Dubinsky, Cathryn Edwards, David Ellinghaus, Lynnette R Ferguson, Denis Franchimont, Karin Fransen, Richard Gearry, Michel Georges, Christian Gieger, Jürgen Glas, Talin Haritunians, Ailsa Hart, Chris Hawkey, Matija Hedl, Xinli Hu, Tom H Karlsen, Limas Kupcinskas, Subra Kugathasan, Anna Latiano, Debby Laukens, Ian C Lawrance, Charlie W Lees, Edouard Louis, Gillian Mahy, John Mansfield, Angharad R Morgan, Craig Mowat, William Newman, Orazio Palmieri, Cyriel Y Ponsioen, Uros Potocnik, Natalie J Prescott, Miguel Regueiro, Jerome I Rotter, Richard K Russell, Jeremy D Sanderson, Miquel Sans, Jack Satsangi, Stefan Schreiber, Lisa A Simms, Jurgita Sventoraityte, Stephan R Targan, Kent D Taylor, Mark Tremelling, Hein W Verspaget, Martine De Vos, Cisca Wijmenga, David C Wilson, Juliane Winkelmann, Ramnik J Xavier, Sebastian Zeissig, Bin Zhang, Clarence K Zhang, Hongyu Zhao, The International IBD Genetics Consortium, Mark S Silverberg, Vito Annese, Hakon Hakonarson, Steven R Brant, Graham Radford-Smith, Christopher G Mathew, John D Rioux, Eric E Schadt, Mark J Daly, Andre Franke, Miles Parkes, Severine Vermeire, Jeffrey C Barrett, Judy H Cho
Nature. Author manuscript; available in PMC 2013 May 1.
Published in final edited form as: Nature. 2012 Nov 1; 491(7422): 119–124. doi: 10.1038/nature11582
PMCID:
PMC3491803
AbstractArticlePDF–706K
13.
Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer
Ravi K. Nookala, Lars Langemeyer, Angela Pacitto, Bernardo Ochoa-Montaño, Jane C. Donaldson, Beata K. Blaszczyk, Dimitri Y. Chirgadze, Francis A. Barr, J. Fernando Bazan, Tom L. Blundell
Open Biol. 2012 Aug; 2(8): 120071. doi: 10.1098/rsob.120071
PMCID:
PMC3438538
AbstractArticlePDF–1.2M
14.
Meta-Analysis Increases to 71 the Tally of Confirmed Crohn’s Disease Susceptibility Loci
Andre Franke, Dermot P.B. McGovern, Jeffrey C. Barrett, Kai Wang, Graham L. Radford-Smith, Tariq Ahmad, Charlie W. Lees, Tobias Balschun, James Lee, Rebecca Roberts, Carl A. Anderson, Joshua C. Bis, Suzanne Bumpstead, David Ellinghaus, Eleonora M. Festen, Michel Georges, Talin Haritunians, Luke Jostins, Anna Latiano, Christopher G. Mathew, Grant W. Montgomery, Natalie J. Prescott, Jerome I. Rotter, Philip Schumm, Yashoda Sharma, Lisa A. Simms, Kent D. Taylor, David Whiteman, Cisca Wijmenga, Robert N. Baldassano, Murray Barclay, Theodore M. Bayless, Stephan Brand, Carsten Buning, Albert Cohen, Jean-Frederick Colombel, Mario Cottone, Laura Stronati, Ted Denson, Martine De Vos, Renata D’Inca, Marla Dubinsky, Cathryn Edwards, Tim Florin, Denis Franchimont, Richard Gearry, Jürgen Glas, Andre Van Gossum, Stephen L. Guthery, Jonas Halfvarson, Daan Hommes, Jean-Pierre Hugot, Debby Laukens, Ian Lawrance, Marc Lemann, Arie Levine, Cecile Libioulle, Edouard Louis, Craig Mowat, William Newman, Julián Panés, Anne Phillips, Deborah D. Proctor, Miguel Regueiro, Paul Rutgeerts, Jeremy Sanderson, Miquel Sans, Frank Seibold, A. Hillary Steinhart, Pieter C.F. Stokkers, Leif Torkvist, Gerd Kullak Ublick, Soumya Raychaudhuri, Todd Green, Thomas Walters, Stephan R. Targan, Steven R. Brant, John D. Rioux, Mauro D’Amato, Rinse Weersma, Subra Kugathasan, Anne M. Griffiths, John C. Mansfield, Severine Vermeire, Richard H. Duerr, Mark S. Silverberg, Jack Satsangi, Stefan Schreiber, Judy H. Cho, Vito Annese, Hakon Hakonarson, Mark J. Daly, Miles Parkes
Nat Genet. Author manuscript; available in PMC 2012 Mar 12.
Published in final edited form as: Nat Genet. 2010 Dec; 42(12): 1118–1125. doi: 10.1038/ng.717
PMCID:
PMC3299551
ArticlePDF–864K
15.
Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate
Xudong Wu, Michael J. Bradley, Yiying Cai, Daniel Kümmel, Enrique M. De La Cruz, Francis A. Barr, Karin M. Reinisch
Proc Natl Acad Sci U S A. 2011 Nov 15; 108(46): 18672-18677. Published online 2011 Nov 7. doi: 10.1073/pnas.1110415108
PMCID:
PMC3219131
AbstractArticlePDF–1.8M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis
George F. Mells, James A.B. Floyd, Katherine I. Morley, Heather J. Cordell, Christopher S. Franklin, So-Youn Shin, Michael A. Heneghan, James M. Neuberger, Peter T. Donaldson, Darren B. Day, Samantha J. Ducker, Agnes W. Muriithi, Elizabeth F. Wheater, Christopher J. Hammond, Muhammad F. Dawwas, The UK PBC Consortium, The Wellcome Trust Case Control Consortium 3, David E. Jones, Leena Peltonen, Graeme J. Alexander, Richard N. Sandford, Carl A. Anderson
Nat Genet. Author manuscript; available in PMC 2011 Sep 13.
Published in final edited form as: Nat Genet. 2011 Mar 13; 43(4): 329–332. Published online 2011 Mar 13. doi: 10.1038/ng.789
Correction in:
volume 43 on page 1164
PMCID:
PMC3071550
AbstractArticlePDF–284K
18.
Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors
Shin-ichiro Yoshimura, Andreas Gerondopoulos, Andrea Linford, Daniel J. Rigden, Francis A. Barr
J Cell Biol. 2010 Oct 18; 191(2): 367–381. doi: 10.1083/jcb.201008051
PMCID:
PMC2958468
AbstractArticlePDF–9.0M
19.
Analyses of shared genetic factors between asthma and obesity in children
Erik Melén, Blanca E. Himes, John Brehm, Nadia Boutaoui, Barbara J. Klanderman, Jody S. Sylvia, Jessica Lasky-Su
J Allergy Clin Immunol. Author manuscript; available in PMC 2011 Sep 1.
Published in final edited form as: J Allergy Clin Immunol. 2010 Sep; 126(3): 631–7.e1-8. doi: 10.1016/j.jaci.2010.06.030
PMCID:
PMC2941152
AbstractArticlePDF–72K
20.
The Connecdenn Family, Rab35 Guanine Nucleotide Exchange Factors Interfacing with the Clathrin Machinery
Andrea L. Marat, Peter S. McPherson
J Biol Chem. 2010 Apr 2; 285(14): 10627–10637. Published online 2010 Feb 12. doi: 10.1074/jbc.M109.050930
PMCID:
PMC2856271
AbstractArticlePDF–4.0M

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