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Items: 1 to 20 of 221

1.
GPR124 regulates murine brain embryonic angiogenesis and BBB formation by an intracellular domain-independent mechanism
Kanako Yuki, Mario Vallon, Jie Ding, Cara C. Rada, Alan T. Tang, José G. Vilches-Moure, Aaron K. McCormick, Maria F. Henao Echeverri, Samira Alwahabi, Barbara M. Braunger, Süleyman Ergün, Mark L. Kahn, Calvin J. Kuo
Development. 2024 Jun 1; 151(11): dev202794. Published online 2024 Jun 17. doi: 10.1242/dev.202794
PMCID:
PMC11213517
AbstractArticle
2.
Lack of SPNS1 results in accumulation of lysolipids and lysosomal storage disease in mouse models
Hoa T.T. Ha, SiYi Liu, Xuan T.A. Nguyen, Linh K. Vo, Nancy C.P. Leong, Dat T. Nguyen, Shivaranjani Balamurugan, Pei Yen Lim, YaJun Wu, Eunju Seong, Toan Q. Nguyen, Jeongah Oh, Markus R. Wenk, Amaury Cazenave-Gassiot, Zuhal Yapici, Wei-Yi Ong, Margit Burmeister, Long N. Nguyen
JCI Insight. 2024 Apr 22; 9(8): e175462. Published online 2024 Mar 7. doi: 10.1172/jci.insight.175462
PMCID:
PMC11141868
AbstractArticlePDF–2.8M
3.
Foxp1 suppresses cortical angiogenesis and attenuates HIF-1alpha signaling to promote neural progenitor cell maintenance
Jessie E Buth, Catherine E Dyevich, Alexandra Rubin, Chengbing Wang, Lei Gao, Tessa Marks, Michael RM Harrison, Jennifer H Kong, M Elizabeth Ross, Bennett G Novitch, Caroline Alayne Pearson
EMBO Rep. 2024 May; 25(5): 2202–2219. Published online 2024 Apr 10. doi: 10.1038/s44319-024-00131-8
PMCID:
PMC11094073
AbstractArticlePDF–13M
4.
A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis
Jingwen Yang, Lingxin Zhu, Haichun Pan, Hiroki Ueharu, Masako Toda, Qian Yang, Shawn A. Hallett, Lorin E. Olson, Yuji Mishina
J Clin Invest. 2024 Apr 15; 134(8): e165787. Published online 2024 Mar 11. doi: 10.1172/JCI165787
PMCID:
PMC11014657
AbstractArticlePDF–16M
5.
Expression of the monocarboxylate transporter MCT1 is required for virus-specific mouse CD8+ T cell memory development
Stefania D’Aria, Céline Maquet, Shuang Li, Suveera Dhup, Anouk Lepez, Arnaud Kohler, Vincent F. Van Hée, Rajesh K. Dadhich, Marine Frenière, Fabienne Andris, Ivan Nemazanyy, Pierre Sonveaux, Bénédicte Machiels, Laurent Gillet, Michel Y. Braun
Proc Natl Acad Sci U S A. 2024 Mar 26; 121(13): e2306763121. Published online 2024 Mar 18. doi: 10.1073/pnas.2306763121
PMCID:
PMC10990098
AbstractArticlePDF–4.6M
6.
Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin
Uttkarsh Ayyangar, Aneesh Karkhanis, Heather Tay, Aliya Farissa Binte Afandi, Oindrila Bhattacharjee, Lalitha KS, Sze Han Lee, James Chan, Srikala Raghavan
EMBO J. 2024 Apr; 43(7): 1113–1134. Published online 2024 Feb 28. doi: 10.1038/s44318-024-00039-y
PMCID:
PMC10987662
AbstractArticlePDF–12M
7.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
8.
GLUT3 promotes macrophage signaling and function via RAS-mediated endocytosis in atopic dermatitis and wound healing
Dong-Min Yu, Jiawei Zhao, Eunice E. Lee, Dohun Kim, Ruchika Mahapatra, Elysha K. Rose, Zhiwei Zhou, Calvin Hosler, Abdullah El Kurdi, Jun-Yong Choe, E. Dale Abel, Gerta Hoxhaj, Kenneth D. Westover, Raymond J. Cho, Jeffrey B. Cheng, Richard C. Wang
J Clin Invest. 2023 Nov 1; 133(21): e170706. Published online 2023 Nov 1. doi: 10.1172/JCI170706
PMCID:
PMC10617774
AbstractArticlePDF–11M
9.
Combined GLUT1 and OXPHOS inhibition eliminates acute myeloid leukemia cells by restraining their metabolic plasticity
Maria Rodriguez-Zabala, Ramprasad Ramakrishnan, Katrin Reinbach, Somadri Ghosh, Leal Oburoglu, Antoni Falqués-Costa, Kishan Bellamkonda, Mats Ehinger, Pablo Peña-Martínez, Noelia Puente-Moncada, Henrik Lilljebjörn, Jörg Cammenga, Cornelis Jan Pronk, Vladimir Lazarevic, Thoas Fioretos, Anna K. Hagström-Andersson, Niels-Bjarne Woods, Marcus Järås
Blood Adv. 2023 Sep 26; 7(18): 5382–5395. Published online 2023 Jul 30. doi: 10.1182/bloodadvances.2023009967
PMCID:
PMC10509671
AbstractArticlePDF–1.4M
10.
Lactate-dependent transcriptional regulation controls mammalian eye morphogenesis
Nozomu Takata, Jason M. Miska, Marc A. Morgan, Priyam Patel, Leah K. Billingham, Neha Joshi, Matthew J. Schipma, Zachary J. Dumar, Nikita R. Joshi, Alexander V. Misharin, Ryan B. Embry, Luciano Fiore, Peng Gao, Lauren P. Diebold, Gregory S. McElroy, Ali Shilatifard, Navdeep S. Chandel, Guillermo Oliver
Nat Commun. 2023; 14: 4129. Published online 2023 Jul 14. doi: 10.1038/s41467-023-39672-2
PMCID:
PMC10349100
AbstractArticlePDF–7.7M
11.
miR-455-3p ameliorates pancreatic acinar cell injury by targeting Slc2a1
Yinchu Zhan, Chenlin Chen, Zhiqiang Wu, Feng Zhou, Xinping Yu
PeerJ. 2023; 11: e15612. Published online 2023 Jun 30. doi: 10.7717/peerj.15612
PMCID:
PMC10317017
AbstractArticlePDF–13M
12.
Systemic Reduction of Glut1 Normalizes Retinal Dysfunction, Inflammation, and Oxidative Stress in the Retina of Spontaneous Type 2 Diabetic Mice
Jacob J. Aiello, Maislin C. Bogart, Wai-Ting Chan, Nicholas C. Holoman, Timothy D. Trobenter, Chloe E. Relf, Dana M. Kleinman, Darryl C. De Vivo, Ivy S. Samuels
Am J Pathol. 2023 Jul; 193(7): 927–938. doi: 10.1016/j.ajpath.2023.04.003
PMCID:
PMC10294444
AbstractArticlePDF–2.9M
13.
GLUT1 is redundant in hypoxic and glycolytic nucleus pulposus cells of the intervertebral disc
Shira N. Johnston, Elizabeth S. Silagi, Vedavathi Madhu, Duc H. Nguyen, Irving M. Shapiro, Makarand V. Risbud
JCI Insight. 2023 Apr 24; 8(8): e164883. Published online 2023 Apr 24. doi: 10.1172/jci.insight.164883
PMCID:
PMC10243741
AbstractArticlePDF–17M
14.
Quantitative determination of SLC2A1 variant functional effects in GLUT1 deficiency syndrome
Naeimeh Tayebi, Brian Leon‐Ricardo, Kevin McCall, Elvisa Mehinovic, Kristin Engelstad, Vincent Huynh, Tychele N. Turner, Judy Weisenberg, Liu L. Thio, Paul Hruz, Robin S. B. Williams, Darryl C. De Vivo, Vincent Petit, Gabe Haller, Christina A. Gurnett
Ann Clin Transl Neurol. 2023 May; 10(5): 787–801. Published online 2023 Mar 31. doi: 10.1002/acn3.51767
PMCID:
PMC10187726
AbstractArticlePDF–1.1M
15.
Mustn1 ablation in skeletal muscle results in increased glucose tolerance concomitant with upregulated GLUT expression in male mice
Charles J. Kim, Chanpreet Singh, Christine Lee, Kevin DiMagno, Madison O'Donnell, Marina Kaczmarek, Arhum Ahmed, Jessica Salvo‐Schaich, Alexis Perez, William Letsou, Maria‐Alicia Carrillo Sepulveda, Raddy L. Ramos, Michael Hadjiargyrou
Physiol Rep. 2023 May; 11(9): e15674. Published online 2023 May 11. doi: 10.14814/phy2.15674
PMCID:
PMC10175242
AbstractArticlePDF–5.3M
16.
Neddylation is required for perinatal cardiac development through stimulation of metabolic maturation
Jianqiu Zou, Wenjuan Wang, Yi Lu, Juan Ayala, Kunzhe Dong, Hongyi Zhou, Jinxi Wang, Weiqin Chen, Neal L. Weintraub, Jiliang Zhou, Jie Li, Huabo Su
Cell Rep. Author manuscript; available in PMC 2023 Mar 21.
Published in final edited form as: Cell Rep. 2023 Jan 31; 42(1): 112018. Published online 2023 Jan 19. doi: 10.1016/j.celrep.2023.112018
PMCID:
PMC10029150
AbstractArticlePDF–2.0M
17.
Epidermal Stratification Requires Retromer-Mediated Desmoglein-1 Recycling
Marihan Hegazy, Jennifer L. Koetsier, Amber L. Huffine, Joshua A. Broussard, Brendan M. Godsel, Eran Cohen-Barak, Eli Sprecher, Donald J. Wolfgeher, Stephen J. Kron, Lisa M. Godsel, Kathleen J. Green
Dev Cell. Author manuscript; available in PMC 2023 Dec 19.
Published in final edited form as: Dev Cell. 2022 Dec 19; 57(24): 2683–2698.e8. Published online 2022 Dec 9. doi: 10.1016/j.devcel.2022.11.010
PMCID:
PMC9973369
AbstractArticlePDF–2.9M
18.
Characterization of placental endocrine function and fetal brain development in a mouse model of small for gestational age
Jorge Lopez-Tello, Amanda N. Sferruzzi-Perri
Front Endocrinol (Lausanne) 2023; 14: 1116770. Published online 2023 Feb 10. doi: 10.3389/fendo.2023.1116770
PMCID:
PMC9950515
AbstractArticlePDF–4.2M
19.
Muscle-Specific Ablation of Glucose Transporter 1 (GLUT1) Does Not Impair Basal or Overload-Stimulated Skeletal Muscle Glucose Uptake
Shawna L. McMillin, Parker L. Evans, William M. Taylor, Luke A. Weyrauch, Tyler J. Sermersheim, Steven S. Welc, Monique R. Heitmeier, Richard C. Hresko, Paul W. Hruz, Francoise Koumanov, Geoffrey D. Holman, E. Dale Abel, Carol A. Witczak
Biomolecules. 2022 Dec; 12(12): 1734. Published online 2022 Nov 23. doi: 10.3390/biom12121734
PMCID:
PMC9776291
AbstractArticlePDF–1.1M
20.
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3
Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany
Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527
PMCID:
PMC9603860
AbstractArticlePDF–3.4M

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