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Select item 112220711.

N‐acetyltransferase 10 facilitates tumorigenesis of diffuse large B‐cell lymphoma by regulating AMPK/mTOR signalling through N4‐acetylcytidine modification of SLC30A9

Mengfei Ding, Zhuoya Yu, Tiange Lu, Shunfeng Hu, Xiangxiang Zhou, Xin Wang

Clin Transl Med. 2024 Jul; 14(7): e1747. Published online 2024 Jul 3. doi: 10.1002/ctm2.1747

PMCID:: PMC11222071

Abstract Article PDF–8.7M

Select item 109957012.

NAT10‐mediated mRNA N4‐acetylcytidine modification of MDR1 and BCRP promotes breast cancer progression

Cui‐Cui Zhao, Xuan Sun, Jing Chen, Bill D. Geng

Thorac Cancer. 2024 Apr; 15(10): 820–829. Published online 2024 Feb 26. doi: 10.1111/1759-7714.15262

PMCID:: PMC10995701

Abstract Article PDF–4.3M

Select item 109239143.

N-Acetyltransferase 10 represses Uqcr11 and Uqcrb independently of ac4C modification to promote heart regeneration

Wenya Ma, Yanan Tian, Leping Shi, Jing Liang, Qimeng Ouyang, Jianglong Li, Hongyang Chen, Hongyue Sun, Haoyu Ji, Xu Liu, Wei Huang, Xinlu Gao, Xiaoyan Jin, Xiuxiu Wang, Yining Liu, Yang Yu, Xiaofei Guo, Ye Tian, Fan Yang, Faqian Li, Ning Wang, Benzhi Cai

Nat Commun. 2024; 15: 2137. Published online 2024 Mar 8. doi: 10.1038/s41467-024-46458-7

PMCID:: PMC10923914

Abstract Article PDF–20M

Select item 108988134.

NAT10 promotes the tumorigenesis and progression of laryngeal squamous cell carcinoma through ac4C modification of FOXM1 mRNA

Zengpei Li, Dajun Li, Tianbin Yang, Chen Yao

Cancer Biol Ther. 2023; 24(1): 2274143. Published online 2023 Nov 10. doi: 10.1080/15384047.2023.2274143

PMCID:: PMC10898813

Abstract Article PDF–3.9M

Select item 108050745.

N-acetyltransferase 10 regulates alphavirus replication via N4-acetylcytidine (ac4C) modiﬁcation of the lymphocyte antigen six family member E (LY6E) mRNA

Yamei Dang, Jia Li, Yuchang Li, Yuan Wang, Yajing Zhao, Ningbo Zhao, Wanying Li, Hui Zhang, Chuantao Ye, Hongwei Ma, Liang Zhang, He Liu, Yangchao Dong, Min Yao, Yingfeng Lei, Zhikai Xu, Fanglin Zhang, Wei Ye

J Virol. 2024 Jan; 98(1): e01350-23. Published online 2024 Jan 3. doi: 10.1128/jvi.01350-23

PMCID:: PMC10805074

Abstract Article PDF–11M

Select item 108003546.

RNPS1 stabilizes NAT10 protein to facilitate translation in cancer via tRNA ac⁴C modification

Xiaochen Wang, Rongsong Ling, Yurong Peng, Weiqiong Qiu, Demeng Chen

Int J Oral Sci. 2024; 16: 6. Published online 2024 Jan 22. doi: 10.1038/s41368-023-00276-7

PMCID:: PMC10800354

Abstract Article PDF–3.0M

Select item 107864157.

N-acetyltransferase NAT10 controls cell fates via connecting mRNA cytidine acetylation to chromatin signaling

Zhensheng Hu, Yunkun Lu, Jie Cao, Lianyu Lin, Xi Chen, Ziyu Zhou, Jiaqi Pu, Guo Chen, Xiaojie Ma, Qian Deng, Yan Jin, Liling Jiang, Yuhan Li, Tengwei Li, Jianzhao Liu, Saiyong Zhu

Sci Adv. 2024 Jan 12; 10(2): eadh9871. Published online 2024 Jan 12. doi: 10.1126/sciadv.adh9871

PMCID:: PMC10786415

Abstract Article PDF–8.3M

Select item 107700818.

CLIC3 interacts with NAT10 to inhibit N4-acetylcytidine modification of p21 mRNA and promote bladder cancer progression

Yujun Shuai, Hui Zhang, Changhao Liu, Junting Wang, Yangkai Jiang, Jiayin Sun, Xincheng Gao, Xiaochen Bo, Xingyuan Xiao, Xin Liao, Chao Huang, Hebing Chen, Guosong Jiang

Cell Death Dis. 2024 Jan; 15(1): 9. Published online 2024 Jan 5. doi: 10.1038/s41419-023-06373-z

PMCID:: PMC10770081

Abstract Article PDF–6.9M

Select item 107649589.

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang

Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6

PMCID:: PMC10764958

Abstract Article PDF–4.4M

Select item 1075976110.

Decreased expression of NAT10 in peripheral blood mononuclear cells from new-onset ankylosing spondylitis and its clinical significance

Qing Luo, Juxiang Zhu, Shiqian Wang, Peng fu, Biqi Fu, Zikun Huang, Junming Li

Arthritis Res Ther. 2024; 26: 7. Published online 2024 Jan 2. doi: 10.1186/s13075-023-03250-0

PMCID:: PMC10759761

Abstract Article PDF–1.7M

Select item 1064627311.

NAT10/ac4C/FOXP1 Promotes Malignant Progression and Facilitates Immunosuppression by Reprogramming Glycolytic Metabolism in Cervical Cancer

Xiaona Chen, Yi Hao, Yong Liu, Sheng Zhong, Yuehua You, Keyi Ao, Tuotuo Chong, Xiaomin Luo, Minuo Yin, Ming Ye, Hui He, Anwei Lu, Jianjun Chen, Xin Li, Jian Zhang, Xia Guo

Adv Sci (Weinh) 2023 Nov; 10(32): 2302705. Published online 2023 Oct 11. doi: 10.1002/advs.202302705

PMCID:: PMC10646273

Abstract Article PDF–13M

Select item 1063708512.

N‐acetyltransferase 10 promotes the progression of oral squamous cell carcinoma through N4‐acetylcytidine RNA acetylation of MMP1 mRNA

Yi Liu, Hui Huang, Cun‐bao Zhang, Hua‐nan Fan

Cancer Sci. 2023 Nov; 114(11): 4202–4215. Published online 2023 Sep 13. doi: 10.1111/cas.15946

PMCID:: PMC10637085

Abstract Article PDF–46M

Select item 1062019813.

N4-acetylcytidine-dependent GLMP mRNA stabilization by NAT10 promotes head and neck squamous cell carcinoma metastasis and remodels tumor microenvironment through MAPK/ERK signaling pathway

Yuanyuan Liu, Xing Wang, Yuying Liu, Jianqiang Yang, Wei Mao, Chen Feng, Xiaoliang Wu, Xinwei Chen, Lixiao Chen, Pin Dong

Cell Death Dis. 2023 Nov; 14(11): 712. Published online 2023 Nov 1. doi: 10.1038/s41419-023-06245-6

PMCID:: PMC10620198

Abstract Article PDF–7.6M

Select item 1061767314.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 1048467915.

NAT10-mediated N4-acetylcytidine mRNA modification regulates self-renewal in human embryonic stem cells

Rucong Liu, Zibaguli Wubulikasimu, Runze Cai, Fanyi Meng, Qinghua Cui, Yuan Zhou, Yang Li

Nucleic Acids Res. 2023 Sep 8; 51(16): 8514–8531. Published online 2023 Jul 27. doi: 10.1093/nar/gkad628

PMCID:: PMC10484679

Abstract Article PDF–2.0M

Select item 1023742216.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1016456417.

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing

Yingxiao Chen, Yanping Li, Roselyn S Dai, Jonathan C Savage, Ujwal Shinde, John Klimek, Larry L David, Emma A Young, Markus Hafner, Rosalie C Sears, Xiao-Xin Sun, Mu-Shui Dai

Nucleic Acids Res. 2023 May 8; 51(8): 3934–3949. Published online 2023 Mar 13. doi: 10.1093/nar/gkad140

PMCID:: PMC10164564

Abstract Article PDF–3.8M

Select item 1015161518.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120