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Select item 111589391.

Combined mobilization and stimulation of tumor‐infiltrating dendritic cells and natural killer cells with Flt3 ligand and IL‐18 in vivo induces systemic antitumor immunity

Tetsuya Saito, Takuya Takayama, Tadashi Osaki, Shigenori Nagai, Toshihiro Suzuki, Marimo Sato, Hiroyuki Kuwano, Hideaki Tahara

Cancer Sci. 2008 Oct; 99(10): 2028–2036. Published online 2008 Oct 13. doi: 10.1111/j.1349-7006.2008.00907.x

PMCID:: PMC11158939

Abstract Article PDF–595K

Select item 110769882.

High FLT3 expression increases immune‐cell infiltration in the tumor microenvironment and correlates with prolonged disease‐free survival in patients with non‐small cell lung cancer

Łukasz Kuncman, Magdalena Orzechowska, Tomasz Milecki, Jakub Kucharz, Jacek Fijuth

Mol Oncol. 2024 May; 18(5): 1316–1326. Published online 2024 Feb 7. doi: 10.1002/1878-0261.13597

PMCID:: PMC11076988

Abstract Article PDF–2.7M

Select item 109693213.

Prevalence of FMS-like tyrosine kinase 3/internal tandem duplication (FLT3/ITD+) in de novo acute myeloid leukemia patients categorized according to cytogenetic risk

Everson Augusto Krum, Mihoko Yamamoto, Maria de Lourdes Lopes Ferrari Chauffaille

Sao Paulo Med J. 2009; 127(1): 23–27. Published online 2009 May 11. doi: 10.1590/S1516-31802009000100006

PMCID:: PMC10969321

Abstract Article PDF–149K

Select item 109436914.

Leukemic mutation FLT3-ITD is retained in dendritic cells and disrupts their homeostasis leading to expanded Th17 frequency

Patrick A. Flynn, Mark D. Long, Yoko Kosaka, Nicola Long, Jessica S. Mulkey, Jesse L. Coy, Anupriya Agarwal, Evan F. Lind

Front Immunol. 2024; 15: 1297338. Published online 2024 Mar 1. doi: 10.3389/fimmu.2024.1297338

PMCID:: PMC10943691

Abstract Article PDF–6.1M

Select item 108035565.

Characterisation of FLT3 alterations in childhood acute lymphoblastic leukaemia

Angela Gutierrez-Camino, Chantal Richer, Manon Ouimet, Claire Fuchs, Sylvie Langlois, Fida Khater, Maxime Caron, Patrick Beaulieu, Pascal St-Onge, Alain R. Bataille, Daniel Sinnett

Br J Cancer. 2024 Feb 10; 130(2): 317–326. Published online 2023 Dec 4. doi: 10.1038/s41416-023-02511-8

PMCID:: PMC10803556

Abstract Article PDF–1.1M

Select item 105978406.

A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo

Eirini Giannakopoulou, Madeleine Lehander, Stina Virding Culleton, Weiwen Yang, Yingqian Li, Terhi Karpanen, Tetsuichi Yoshizato, Even H. Rustad, Morten Milek Nielsen, Ravi Chand Bollineni, Trung T. Tran, Marina Delic-Sarac, Thea Johanne Gjerdingen, Karolos Douvlataniotis, Maarja Laos, Muhammad Ali, Amy Hillen, Stefania Mazzi, Desmond Wai Loon Chin, Adi Mehta, Jeppe Sejerø Holm, Amalie Kai Bentzen, Marie Bill, Marieke Griffioen, Tobias Gedde-Dahl, Sören Lehmann, Sten Eirik W. Jacobsen, Petter S. Woll, Johanna Olweus

Nat Cancer. 2023; 4(10): 1474–1490. Published online 2023 Oct 2. doi: 10.1038/s43018-023-00642-8

PMCID:: PMC10597840

Abstract Article PDF–20M

Select item 105586187.

Targeting conditioned media dependencies and FLT-3 in chronic lymphocytic leukemia

Salma Parvin, Aditi Aryal, Shanye Yin, Geoffrey G. Fell, Matthew S. Davids, Catherine J. Wu, Anthony Letai

Blood Adv. 2023 Oct 10; 7(19): 5877–5889. Published online 2023 Jul 20. doi: 10.1182/bloodadvances.2022008207

PMCID:: PMC10558618

Abstract Article PDF–1.2M

Select item 105290568.

Insight and Recommendations for Fragile X-Premutation-Associated Conditions from the Fifth International Conference on FMR1 Premutation

Flora Tassone, Dragana Protic, Emily Graves Allen, Alison D. Archibald, Anna Baud, Ted W. Brown, Dejan B. Budimirovic, Jonathan Cohen, Brett Dufour, Rachel Eiges, Nicola Elvassore, Lidia V. Gabis, Samantha J. Grudzien, Deborah A. Hall, David Hessl, Abigail Hogan, Jessica Ezzell Hunter, Peng Jin, Poonnada Jiraanont, Jessica Klusek, R. Frank Kooy, Claudine M. Kraan, Cecilia Laterza, Andrea Lee, Karen Lipworth, Molly Losh, Danuta Loesch, Reymundo Lozano, Marsha R. Mailick, Apostolos Manolopoulos, Veronica Martinez-Cerdeno, Yingratana McLennan, Robert M. Miller, Federica Alice Maria Montanaro, Matthew W. Mosconi, Sarah Nelson Potter, Melissa Raspa, Susan M. Rivera, Katharine Shelly, Peter K. Todd, Katarzyna Tutak, Jun Yi Wang, Anne Wheeler, Tri Indah Winarni, Marwa Zafarullah, Randi J. Hagerman

Cells. 2023 Sep; 12(18): 2330. Published online 2023 Sep 21. doi: 10.3390/cells12182330

PMCID:: PMC10529056

Abstract Article PDF–4.4M

Select item 103178309.

NUP98::Nsd1 and FLT3-ITD collaborate to generate acute myeloid leukemia

Toshihiro Matsukawa, Mianmian Yin, Nupur Nigam, Vijay Negi, Li Li, Donald Small, Yuelin J. Zhu, Robert L. Walker, Paul S. Meltzer, Peter D. Aplan

Leukemia. 2023; 37(7): 1545–1548. Published online 2023 May 5. doi: 10.1038/s41375-023-01913-0

PMCID:: PMC10317830

Article PDF–2.2M

Select item 1023042910.

Concomitant targeting of FLT3 and BTK overcomes FLT3 inhibitor resistance in acute myeloid leukemia through the inhibition of autophagy

Weiguo Zhang, Guopan Yu, Hongying Zhang, Mahesh Basyal, Charlie Ly, Bin Yuan, Vivian Ruvolo, Sujan Piya, Seemana Bhattacharya, Qi Zhang, Gautam Borthakur, Venkata L. Battula, Marina Konopleva, William G. Rice, Michael Andreeff

Haematologica. 2023 Jun 1; 108(6): 1500–1514. Published online 2022 Oct 13. doi: 10.3324/haematol.2022.280884

PMCID:: PMC10230429

Abstract Article PDF–3.0M

Select item 1023040411.

Disrupting autophagy in FLT3-mutant acute myeloid leukemia

Steven Grant

Haematologica. 2023 Jun 1; 108(6): 1458–1460. Published online 2022 Nov 17. doi: 10.3324/haematol.2022.282054

PMCID:: PMC10230404

Article PDF–1.2M

Select item 1008238012.

FLT3^ITD drives context-specific changes in cell identity and variable interferon dependence during AML initiation

Yanan Li, Wei Yang, Riddhi M. Patel, Emily B. Casey, Elisabeth Denby, Jonny Mendoza-Castrejon, Priscilla Rodriguez-Lopez, Jeffrey A. Magee

Blood. 2023 Mar 23; 141(12): 1442–1456. Published online 2022 Nov 21. doi: 10.1182/blood.2022016889

PMCID:: PMC10082380

Abstract Article

Select item 999318313.

DNA Sequencing to Detect Residual Disease in Adults With Acute Myeloid Leukemia Prior to Hematopoietic Cell Transplant

Laura W. Dillon, Gege Gui, Kristin M. Page, Niveditha Ravindra, Zoë C. Wong, Georgia Andrew, Devdeep Mukherjee, Scott L. Zeger, Firas El Chaer, Stephen Spellman, Alan Howard, Karen Chen, Jeffery Auletta, Steven M. Devine, Antonio Martin Jimenez Jimenez, Marcos J. G. De Lima, Mark R. Litzow, Partow Kebriaei, Wael Saber, Daniel J. Weisdorf, Christopher S. Hourigan

JAMA. 2023 Mar 7; 329(9): 745–755. Published online 2023 Mar 7. doi: 10.1001/jama.2023.1363

PMCID:: PMC9993183

Abstract Article

Select item 991056914.

FLT3 functional low-frequency variant rs76428106-C is associated with susceptibility to systemic sclerosis

Javier Martínez-López, Martin Kerick, Lourdes Ortiz-Fernández, Marialbert Acosta-Herrera, Ana Márquez, Javier Martín

Rheumatology (Oxford) 2023 Feb; 62(SI): SI138–SI142. Published online 2022 Jul 25. doi: 10.1093/rheumatology/keac406

PMCID:: PMC9910569

Abstract Article PDF–240K

Select item 982085015.

Novel investigational approaches for high-risk genetic subsets of AML: TP53, KMT2A, FLT3

Kieran D. Sahasrabudhe, Alice S. Mims

Hematology Am Soc Hematol Educ Program. 2022 Dec 9; 2022(1): 15-22. Published online 2022 Dec 9. doi: 10.1182/hematology.2022000325

PMCID:: PMC9820850

Abstract Article PDF–398K

Select item 979129216.

Association between FLT3-ITD and additional chromosomal abnormalities in the prognosis of acute promyelocytic leukemia

Minh Phuong Vu, Cuc Nhung Nguyen, Hoang Vu, Tuyet Mai Nguyen, Tuan Tung Nguyen, Phuong Thao Pham

J Int Med Res. 2022 Dec; 50(12): 03000605221138490. Published online 2022 Dec 20. doi: 10.1177/03000605221138490

PMCID:: PMC9791292

Abstract Article PDF–454K

Select item 975343317.

Clinical and molecular features of FLT3 juxtamembrane domain missense mutations in acute myeloid leukaemia

Christopher E. Jensen, Nathan D. Montgomery, Jonathan Galeotti, Matthew C. Foster, Joshua F. Zeidner

J Cell Mol Med. 2022 Dec; 26(24): 6079–6082. Published online 2022 Nov 28. doi: 10.1111/jcmm.17608

PMCID:: PMC9753433

Article PDF–236K

Select item 970704418.

FLT3 Gene Mutations in Acute Myeloid Leukemia Patients in Northeast Thailand

Nang Ei Ei Aung, Supawadee Yamsri, Nattiya Teawtrakul, Piyawan Kamsaen, Supan Fucharoen

Med Sci Monit Basic Res. 2022; 28: e937446-1–e937446-11. Published online 2022 Nov 24. doi: 10.12659/MSMBR.937446

PMCID:: PMC9707044

Abstract Article PDF–1.2M

Select item 965263719.

Lack of FLT3-ITD in Tunisian childhood acute lymphoblastic leukemia

Rim Frikha, Nawel Abdellaoui, Olfa Kassar, Tarek Rebai

Afr Health Sci. 2022 Jun; 22(2): 318–322. doi: 10.4314/ahs.v22i2.35

PMCID:: PMC9652637

Abstract Article PDF–286K

Select item 957007820.

FBP1-Altered Carbohydrate Metabolism Reduces Leukemic Viability through Activating P53 and Modulating the Mitochondrial Quality Control System In Vitro

Yi Xu, Lily Tran, Janet Tang, Vinh Nguyen, Elisabeth Sewell, Jeffrey Xiao, Christopher Hino, Samiksha Wasnik, Olivia L. Francis-Boyle, Ke K. Zhang, Linglin Xie, Jiang F. Zhong, David J. Baylink, Chien-Shing Chen, Mark E. Reeves, Huynh Cao

Int J Mol Sci. 2022 Oct; 23(19): 11387. Published online 2022 Sep 27. doi: 10.3390/ijms231911387

PMCID:: PMC9570078

Abstract Article PDF–3.1M

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