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Items: 1 to 20 of 71

1.
Long non-coding RNA lung cancer-associated transcript 1 regulates ferroptosis via microRNA-34a-5p-mediated GTP cyclohydrolase 1 downregulation in lung cancer cells
Fumin Tai, Rui Zhai, Kexin Ding, Yaocang Zhang, Hexi Yang, Hujie Li, Qiong Wang, Zhengyue Cao, Changhui Ge, Hanjiang Fu, Fengjun Xiao, Xiaofei Zheng
Int J Oncol. 2024 Jun; 64(6): 64. Published online 2024 May 10. doi: 10.3892/ijo.2024.5652
PMCID:
PMC11095600
AbstractArticlePDF–5.3M
2.
Nitrosative stress induced by homocysteine thiolactone drives vascular cognitive impairments via GTP cyclohydrolase 1 S-nitrosylation in vivo
Ya-Ling Yin, Yuan Chen, Feng Ren, Lu Wang, Mo-Li Zhu, Jun-Xiu Lu, Qian-Qian Wang, Cheng-Biao Lu, Chao Liu, Yong-Ping Bai, Shuang-Xi Wang, Jian-Zhi Wang, Peng Li
Redox Biol. 2022 Dec; 58: 102540. Published online 2022 Nov 13. doi: 10.1016/j.redox.2022.102540
PMCID:
PMC9673109
AbstractArticlePDF–9.8M
3.
CircLRFN5 inhibits the progression of glioblastoma via PRRX2/GCH1 mediated ferroptosis
Yang Jiang, Junshuang Zhao, Rongqing Li, Yingliang Liu, Lin Zhou, Chengbin Wang, Caihong Lv, Liang Gao, Daming Cui
J Exp Clin Cancer Res. 2022; 41: 307. Published online 2022 Oct 20. doi: 10.1186/s13046-022-02518-8
Correction in:
J Exp Clin Cancer Res. 2022; 41: 320.
PMCID:
PMC9583503
AbstractArticlePDF–5.3M
4.
Association analysis of SYT11, FGF20, GCH1 rare variants in Parkinson's disease
Jia‐li Pu, Zhi‐Hao Lin, Ran Zheng, Yi‐Qun Yan, Nai‐jia Xue, Xin‐zhen Yin, Bao‐Rong Zhang
CNS Neurosci Ther. 2022 Jan; 28(1): 175–177. Published online 2021 Oct 21. doi: 10.1111/cns.13745
PMCID:
PMC8673698
ArticlePDF–472K
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
Oxidative Stress, GTPCH1, and Endothelial Nitric Oxide Synthase Uncoupling in Hypertension
Yin Wu, Ye Ding, Tharmarajan Ramprasath, Ming-Hui Zou
Antioxid Redox Signal. March 2021; 34(9): 750–764. Published online 2021 Feb 24. doi: 10.1089/ars.2020.8112
PMCID:
PMC7910417
AbstractArticlePDF–941K
7.
A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I
Rebecca Ebenhoch, Simone Prinz, Susann Kaltwasser, Deryck J. Mills, Robert Meinecke, Martin Rübbelke, Dirk Reinert, Margit Bauer, Lisa Weixler, Markus Zeeb, Janet Vonck, Herbert Nar
Proc Natl Acad Sci U S A. 2020 Dec 15; 117(50): 31838–31849. Published online 2020 Nov 23. doi: 10.1073/pnas.2013473117
PMCID:
PMC7750480
AbstractArticlePDF–2.1M
8.
GCH1 variants contribute to the risk and earlier age-at-onset of Parkinson’s disease: a two-cohort case-control study
Hong-xu Pan, Yu-wen Zhao, Jun-pu Mei, Zheng-huan Fang, Yige Wang, Xun Zhou, Yang-jie Zhou, Rui Zhang, Kai-lin Zhang, Li Jiang, Qian Zeng, Yan He, Zheng Wang, Zhen-hua Liu, Qian Xu, Qi-ying Sun, Yang Yang, Ya-cen Hu, Ya-se Chen, Juan Du, Li-fang Lei, Hai-nan Zhang, Chun-yu Wang, Xin-xiang Yan, Lu Shen, Hong Jiang, Jie-qiong Tan, Jin-chen Li, Bei-sha Tang, Ji-feng Guo
Transl Neurodegener. 2020; 9: 31. Published online 2020 Aug 4. doi: 10.1186/s40035-020-00212-3
PMCID:
PMC7401216
AbstractArticlePDF–2.0M
9.
A tetrahydrobiopterin deficit finding in schizophrenia: A confirmation study
James D. Clelland, Jennifer Smeed, Serge Cremers, Catherine L. Clelland
Schizophr Res. Author manuscript; available in PMC 2020 May 25.
Published in final edited form as: Schizophr Res. 2019 Aug; 210: 316–318. Published online 2019 Jun 21. doi: 10.1016/j.schres.2019.06.006
PMCID:
PMC7247802
ArticlePDF–470K
10.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
11.
GCH1 (rs841) polymorphism in the nitric oxide-forming pathway has protective effects on obstructive sleep apnea
Samaneh Sheikhi Kouhsar, Mohammadreza Bigdeli, Yadollah Shakiba, Khosro Sadeghniiat
Sci Rep. 2019; 9: 18664. Published online 2019 Dec 9. doi: 10.1038/s41598-019-55244-1
PMCID:
PMC6901474
AbstractArticlePDF–935K
12.
Reactive species balance via GTP cyclohydrolase I regulates glioblastoma growth and tumor initiating cell maintenance
Anh Nhat Tran, Kiera Walker, David G Harrison, Wei Chen, James Mobley, Lauren Hocevar, James R Hackney, Randee S Sedaka, Jennifer S Pollock, Matthew S Goldberg, Dolores Hambardzumyan, Sara J Cooper, Yancey Gillespie, Anita B Hjelmeland
Neuro Oncol. 2018 Jul; 20(8): 1055–1067. Published online 2018 Feb 2. doi: 10.1093/neuonc/noy012
PMCID:
PMC6280150
AbstractArticlePDF–6.8M
13.
Common and rare GCH1 variants are associated with Parkinson disease
Uladzislau Rudakou, Bouchra Ouled Amar Bencheikh, Jennifer A. Ruskey, Lynne Krohn, Sandra B. Laurent, Dan Spiegelman, Christopher Liong, Stanley Fahn, Cheryl Waters, Oury Monchi, Edward A. Fon, Yves Dauvilliers, Roy N. Alcalay, Nicolas Dupré, Ziv Gan-Or
Neurobiol Aging. Author manuscript; available in PMC 2020 Jan 1.
Published in final edited form as: Neurobiol Aging. 2019 Jan; 73: 231.e1–231.e6. Published online 2018 Sep 15. doi: 10.1016/j.neurobiolaging.2018.09.008
PMCID:
PMC6251729
AbstractArticlePDF–153K
14.
Nicotine induces endothelial dysfunction and promotes atherosclerosis via GTPCH1
Jingyuan Li, Shangming Liu, Guangqing Cao, Yuanyuan Sun, Weiqian Chen, Fajin Dong, Jinfeng Xu, Cheng Zhang, Wencheng Zhang
J Cell Mol Med. 2018 Nov; 22(11): 5406–5417. Published online 2018 Aug 9. doi: 10.1111/jcmm.13812
PMCID:
PMC6201367
AbstractArticlePDF–3.4M
15.
Genetic variants of GCH1 associate with chronic and acute crisis pain in African Americans with sickle cell disease
Nilanjana Sadhu, Ellie H. Jhun, Yingwei Yao, Ying He, Robert E. Molokie, Diana J. Wilkie, Zaijie Jim Wang
Exp Hematol. Author manuscript; available in PMC 2019 Oct 1.
Published in final edited form as: Exp Hematol. 2018 Oct; 66: 42–49. Published online 2018 Jul 19. doi: 10.1016/j.exphem.2018.07.004
PMCID:
PMC6175655
AbstractArticlePDF–653K
16.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
17.
Dopa-Responsive Dystonia in Han Chinese Patients: One Novel Heterozygous Mutation in GTP Cyclohydrolase 1 (GCH1) and Three Known Mutations in TH
Kunfang Yang, Rongrong Yin, Xiaoping Lan, Yuanfeng Zhang, Hongyi Cheng, Simei Wang, Chunmei Wang, Yanfen Lu, Jiaming Xi, Qin Lu, Jianjun Huang, Yucai Chen
Med Sci Monit. 2018; 24: 751–757. Published online 2018 Feb 6. doi: 10.12659/MSM.907288
PMCID:
PMC5810615
AbstractArticlePDF–573K
18.
Complex and Dynamic Chromosomal Rearrangements in a Family With Seemingly Non-Mendelian Inheritance of Dopa-Responsive Dystonia
Katja Lohmann, Claire Redin, Holger Tönnies, Susan B. Bressman, Jose Ignacio Martin Subero, Karin Wiegers, Frauke Hinrichs, Yorck Hellenbroich, Aleksandar Rakovic, Deborah Raymond, Laurie J. Ozelius, Eberhard Schwinger, Reiner Siebert, Michael E. Talkowski, Rachel Saunders-Pullman, Christine Klein
JAMA Neurol. 2017 Jul; 74(7): 806–812. Prepublished online 2017 May 30. Published online 2017 Jul 10. doi: 10.1001/jamaneurol.2017.0666
PMCID:
PMC5710536
AbstractArticle
19.
Transgenic overexpression of GTP cyclohydrolase 1 in cardiomyocytes ameliorates post-infarction cardiac remodeling
Yanan Liu, Shelley L. Baumgardt, Juan Fang, Yang Shi, Shigang Qiao, Zeljko J. Bosnjak, Jeannette Vásquez-Vivar, Zhengyuan Xia, David C. Warltier, Judy R. Kersten, Zhi-Dong Ge
Sci Rep. 2017; 7: 3093. Published online 2017 Jun 8. doi: 10.1038/s41598-017-03234-6
PMCID:
PMC5465102
AbstractArticlePDF–2.9M
20.
GCH1 plays a role in the high-altitude adaptation of Tibetans
Yong-Bo Guo, Yao-Xi He, Chao-Ying Cui, zhuluobu Ou, makangzhuo Bai, jizhuoma Duo, jiquzong De, ba Bian, Peng Yi, Cai-juan Bai, galanzi Gong, Yong-Yue Pan, la Qu, min Kang, yangji Ciren, mayangji Bai, Wei Guo, la Yang, Hui Zhang, Xiao-Ming Zhang, Wang-Shan Zheng, Shu-Hua Xu, Hua Chen, Sheng-Guo Zhao, Yuan Cai, Shi-Ming Liu, Wu Tian-Yi, Xue-Bin Qi, Bing Su
Zool Res. 2017 May 18; 38(3): 155–162. Published online 2017 May 18. doi: 10.24272/j.issn.2095-8137.2017.037
PMCID:
PMC5460084
AbstractArticlePDF–1.8M

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