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Items: 1 to 20 of 47

1.
Structural and biochemical insights into NEIL2’s preference for abasic sites
Brian E Eckenroth, Joshua D Bumgarner, Olivia Matsumoto-Elliott, Sheila S David, Sylvie Doublié
Nucleic Acids Res. 2023 Dec 11; 51(22): 12508–12521. Published online 2023 Nov 16. doi: 10.1093/nar/gkad1075
PMCID:
PMC10711445
AbstractArticlePDF–2.6M
2.
The DNA glycosylase NEIL2 is protective during SARS-CoV-2 infection
Nisha Tapryal, Anirban Chakraborty, Kaushik Saha, Azharul Islam, Lang Pan, Koa Hosoki, Ibrahim M. Sayed, Jason M. Duran, Joshua Alcantara, Vanessa Castillo, Courtney Tindle, Altaf H. Sarker, Maki Wakamiya, Victor J. Cardenas, Gulshan Sharma, Laura E. Crotty Alexander, Sanjiv Sur, Debashis Sahoo, Gourisankar Ghosh, Soumita Das, Pradipta Ghosh, Istvan Boldogh, Tapas K. Hazra
Nat Commun. 2023; 14: 8169. Published online 2023 Dec 9. doi: 10.1038/s41467-023-43938-0
PMCID:
PMC10710473
AbstractArticlePDF–2.5M
3.
A Low-Activity Polymorphic Variant of Human NEIL2 DNA Glycosylase
Zarina I. Kakhkharova, Dmitry O. Zharkov, Inga R. Grin
Int J Mol Sci. 2022 Feb; 23(4): 2212. Published online 2022 Feb 17. doi: 10.3390/ijms23042212
PMCID:
PMC8879280
AbstractArticlePDF–2.4M
4.
Mendelian Randomization Analysis Identified Potential Genes Pleiotropically Associated with Polycystic Ovary Syndrome
Qian Sun, Yuan Gao, Jingyun Yang, Jiayi Lu, Wen Feng, Wen Yang
Reprod Sci. 2022 Mar; 29(3): 1028–1037. Published online 2021 Oct 26. doi: 10.1007/s43032-021-00776-z
PMCID:
PMC8547723
AbstractArticlePDF–2.8M
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
NEIL1 and NEIL2 Are Recruited as Potential Backup for OGG1 upon OGG1 Depletion or Inhibition by TH5487
Bishoy M. F. Hanna, Maurice Michel, Thomas Helleday, Oliver Mortusewicz
Int J Mol Sci. 2021 May; 22(9): 4542. Published online 2021 Apr 27. doi: 10.3390/ijms22094542
PMCID:
PMC8123590
AbstractArticlePDF–2.8M
7.
Unique Structural Features of Mammalian NEIL2 DNA Glycosylase Prime Its Activity for Diverse DNA Substrates and Environments
Brian E. Eckenroth, Vy Bao Cao, April M. Averill, Julie A. Dragon, Sylvie Doublié
Structure. Author manuscript; available in PMC 2022 Jan 7.
Published in final edited form as: Structure. 2021 Jan 7; 29(1): 29–42.e4. Published online 2020 Aug 25. doi: 10.1016/j.str.2020.08.001
PMCID:
PMC7796977
AbstractArticlePDF–2.9M
8.
Helicobacter pylori infection downregulates the DNA glycosylase NEIL2, resulting in increased genome damage and inflammation in gastric epithelial cells
Ibrahim M. Sayed, Ayse Z. Sahan, Tatiana Venkova, Anirban Chakraborty, Dibyabrata Mukhopadhyay, Diane Bimczok, Ellen J. Beswick, Victor E. Reyes, Irina Pinchuk, Debashis Sahoo, Pradipta Ghosh, Tapas K. Hazra, Soumita Das
J Biol Chem. 2020 Aug 7; 295(32): 11082–11098. Published online 2020 Jun 9. doi: 10.1074/jbc.RA119.009981
PMCID:
PMC7415988
AbstractArticlePDF–3.8M
9.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
10.
Cervical carcinoma risk associate with genetic polymorphisms of NEIL2 gene in Chinese population and its significance as predictive biomarker
Feng Ye, Jia Liu, Hanzhi Wang, Xiaojing Chen, Qi Cheng, Huaizeng Chen
Sci Rep. 2020; 10: 5136. Published online 2020 Mar 20. doi: 10.1038/s41598-020-62040-9
PMCID:
PMC7083954
AbstractArticlePDF–1.4M
11.
Comprehensive profiling of DNA repair defects in breast cancer identifies a novel class of endocrine therapy resistance drivers
M Anurag, N Punturi, J Hoog, MN Bainbridge, MJ Ellis, S Haricharan
Clin Cancer Res. Author manuscript; available in PMC 2019 Oct 31.
Published in final edited form as: Clin Cancer Res. 2018 Oct 1; 24(19): 4887–4899. Published online 2018 May 23. doi: 10.1158/1078-0432.CCR-17-3702
PMCID:
PMC6822623
AbstractArticlePDF–2.7M
12.
Agrin has a pathological role in the progression of oral cancer
César Rivera, Flávia Silva Zandonadi, Celeste Sánchez-Romero, Ciro Dantas Soares, Daniela Campos Granato, Wilfredo Alejandro González-Arriagada, Adriana Franco Paes Leme
Br J Cancer. 2018 Jun 12; 118(12): 1628–1638. Published online 2018 Jun 6. doi: 10.1038/s41416-018-0135-5
PMCID:
PMC6008410
AbstractArticlePDF–2.6M
13.
Monitoring of the spatial and temporal dynamics of BER/SSBR pathway proteins, including MYH, UNG2, MPG, NTH1 and NEIL1-3, during DNA replication
Karine Ø. Bjørås, Mirta M. L. Sousa, Animesh Sharma, Davi M. Fonseca, Caroline K. Søgaard, Magnar Bjørås, Marit Otterlei
Nucleic Acids Res. 2017 Aug 21; 45(14): 8291–8301. Published online 2017 May 29. doi: 10.1093/nar/gkx476
PMCID:
PMC5737410
AbstractArticlePDF–2.4M
14.
Genomic landscape of DNA repair genes in cancer
Young Kwang Chae, Jonathan F. Anker, Benedito A. Carneiro, Sunandana Chandra, Jason Kaplan, Aparna Kalyan, Cesar A. Santa-Maria, Leonidas C. Platanias, Francis J. Giles
Oncotarget. 2016 Apr 26; 7(17): 23312–23321. Published online 2016 Mar 19. doi: 10.18632/oncotarget.8196
PMCID:
PMC5029628
AbstractArticlePDF–4.1M
15.
Neil DNA glycosylases promote substrate turnover by Tdg during DNA demethylation
Lars Schomacher, Dandan Han, Michael U. Musheev, Khelifa Arab, Sabine Kienhöfer, Annika von Seggern, Christof Niehrs
Nat Struct Mol Biol. Author manuscript; available in PMC 2016 Aug 1.
Published in final edited form as: Nat Struct Mol Biol. 2016 Feb; 23(2): 116–124. Published online 2016 Jan 11. doi: 10.1038/nsmb.3151
PMCID:
PMC4894546
AbstractArticlePDF–2.3M
16.
The cell proliferation antigen Ki-67 organises heterochromatin
Michal Sobecki, Karim Mrouj, Alain Camasses, Nikolaos Parisis, Emilien Nicolas, David Llères, François Gerbe, Susana Prieto, Liliana Krasinska, Alexandre David, Manuel Eguren, Marie-Christine Birling, Serge Urbach, Sonia Hem, Jérôme Déjardin, Marcos Malumbres, Philippe Jay, Vjekoslav Dulic, Denis LJ Lafontaine, Robert Feil, Daniel Fisher
eLife. 2016; 5: e13722. Published online 2016 Mar 7. doi: 10.7554/eLife.13722
PMCID:
PMC4841783
AbstractArticlePDF–5.1M
17.
Abnormal Expressions of DNA Glycosylase Genes NEIL1, NEIL2, and NEIL3 Are Associated with Somatic Mutation Loads in Human Cancer
Kazuya Shinmura, Hisami Kato, Yuichi Kawanishi, Hisaki Igarashi, Masanori Goto, Hong Tao, Yusuke Inoue, Satoki Nakamura, Kiyoshi Misawa, Hiroyuki Mineta, Haruhiko Sugimura
Oxid Med Cell Longev. 2016; 2016: 1546392. Published online 2016 Mar 3. doi: 10.1155/2016/1546392
PMCID:
PMC4794593
AbstractArticlePDF–976K
18.
Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation
Anirban Chakraborty, Maki Wakamiya, Tatiana Venkova-Canova, Raj K. Pandita, Leopoldo Aguilera-Aguirre, Altaf H. Sarker, Dharmendra Kumar Singh, Koa Hosoki, Thomas G. Wood, Gulshan Sharma, Victor Cardenas, Partha S. Sarkar, Sanjiv Sur, Tej K. Pandita, Istvan Boldogh, Tapas K. Hazra
J Biol Chem. 2015 Oct 9; 290(41): 24636–24648. Published online 2015 Aug 5. doi: 10.1074/jbc.M115.658146
PMCID:
PMC4598976
AbstractArticlePDF–1.6M
19.
New paradigms in the repair of oxidative damage in human genome: mechanisms ensuring repair of mutagenic base lesions during replication and involvement of accessory proteins
Arijit Dutta, Chunying Yang, Shiladitya Sengupta, Sankar Mitra, Muralidhar L. Hegde
Cell Mol Life Sci. 2015 May; 72(9): 1679–1698. Published online 2015 Jan 10. doi: 10.1007/s00018-014-1820-z
PMCID:
PMC4395533
AbstractArticlePDF–2.0M
20.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M

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