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Items: 1 to 20 of 82

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Cathepsin S activity controls chronic stress-induced muscle atrophy and dysfunction in mice
Ying Wan, Limei Piao, Shengnan Xu, Xiangkun Meng, Zhe Huang, Aiko Inoue, Hailong Wang, Xueling Yue, Xueying Jin, Yongshan Nan, Guo-Ping Shi, Toyoaki Murohara, Hiroyuki Umegaki, Masafumi Kuzuya, Xian Wu Cheng
Cell Mol Life Sci. 2023 Sep; 80(9): 254. Published online 2023 Aug 17. doi: 10.1007/s00018-023-04888-4
PMCID:
PMC10435624
AbstractArticlePDF–9.1M
3.
Effects of Cathepsin S Inhibition in the Age-Related Dry Eye Phenotype
Jeremias G. Galletti, Kaitlin K. Scholand, Claudia M. Trujillo-Vargas, Wolfgang Haap, Tiago Santos-Ferreira, Christoph Ullmer, Zhiyuan Yu, Cintia S. de Paiva
Invest Ophthalmol Vis Sci. 2023 Aug; 64(11): 7. Published online 2023 Aug 4. doi: 10.1167/iovs.64.11.7
Correction in:
Invest Ophthalmol Vis Sci. 2023 Aug; 64(11): 32.
PMCID:
PMC10414132
AbstractArticlePDF–2.7M
4.
TAP dysfunction in dendritic cells enables non-canonical cross-presentation for T cell priming
Gaëtan Barbet, Priyanka Nair-Gupta, Michael Schotsaert, Stephen T. Yeung, Julien Moretti, Fabian Seyffer, Giorgi Metreveli, Thomas Gardner, Angela Choi, Domenico Tortorella, Robert Tampé, Kamal M. Khanna, Adolfo García-Sastre, J. Magarian Blander
Nat Immunol. Author manuscript; available in PMC 2022 Apr 5.
Published in final edited form as: Nat Immunol. 2021 Apr; 22(4): 497–509. Published online 2021 Mar 31. doi: 10.1038/s41590-021-00903-7
PMCID:
PMC8981674
AbstractArticlePDF–1.5M
5.
Cathepsin S is a novel target for age-related dry eye
Zhiyuan Yu, Jinmiao Li, Gowthaman Govindarajan, Sarah Hamm-Alvarez, Jehan Alam, De-Quan Li, Cintia S. de Paiva
Exp Eye Res. Author manuscript; available in PMC 2023 Jan 1.
Published in final edited form as: Exp Eye Res. 2022 Jan; 214: 108895. Published online 2021 Dec 12. doi: 10.1016/j.exer.2021.108895
PMCID:
PMC8908478
AbstractArticlePDF–1.8M
6.
The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth
Ionel Sandovici, Aikaterini Georgopoulou, Vicente Pérez-García, Antonia Hufnagel, Jorge López-Tello, Brian Y.H. Lam, Samira N. Schiefer, Chelsea Gaudreau, Fátima Santos, Katharina Hoelle, Giles S.H. Yeo, Keith Burling, Moritz Reiterer, Abigail L. Fowden, Graham J. Burton, Cristina M. Branco, Amanda N. Sferruzzi-Perri, Miguel Constância
Dev Cell. 2022 Jan 10; 57(1): 63–79.e8. doi: 10.1016/j.devcel.2021.12.005
PMCID:
PMC8751640
AbstractArticle
7.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
8.
Transfer of exosomal microRNA-203-3p from dendritic cells to bone marrow-derived macrophages reduces development of atherosclerosis by downregulating Ctss in mice
Beiyou Lin, Wenchao Xie, Chunmei Zeng, Xiaodan Wu, Ang Chen, Hao Li, Rina Jiang, Ping Li
Aging (Albany NY) 2021 Jun 15; 13(11): 15638–15658. Published online 2021 Jun 2. doi: 10.18632/aging.103842
PMCID:
PMC8221304
AbstractArticlePDF–1.8M
9.
Targeting lysosomal cysteine protease cathepsin S reveals immunomodulatory therapeutic strategy for oxaliplatin-induced peripheral neuropathy
Szu-Jung Chen, Li-Hsien Chen, Yu-Min Yeh, Chou-Ching K Lin, Peng-Chan Lin, Han-Wei Huang, Meng-Ru Shen, Bo-Wen Lin, Jeng-Chang Lee, Cheng-Che Lee, Yueh-Feng Lee, Huai-Chueh Chiang, Jang-Yang Chang
Theranostics. 2021; 11(10): 4672–4687. Published online 2021 Mar 4. doi: 10.7150/thno.54793
PMCID:
PMC7978314
AbstractArticlePDF–2.6M
10.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
11.
Rab27a Contributes to Cathepsin S Secretion in Lacrimal Gland Acinar Cells
Runzhong Fu, Maria C. Edman, Sarah F. Hamm-Alvarez
Int J Mol Sci. 2021 Feb; 22(4): 1630. Published online 2021 Feb 5. doi: 10.3390/ijms22041630
PMCID:
PMC7914720
AbstractArticlePDF–4.1M
12.
Cathepsin S provokes interleukin-6 (IL-6) trans-signaling through cleavage of the IL-6 receptor in vitro
Charlotte M. Flynn, Yvonne Garbers, Stefan Düsterhöft, Rielana Wichert, Juliane Lokau, Christian H. K. Lehmann, Diana Dudziak, Bernd Schröder, Christoph Becker-Pauly, Stefan Rose-John, Samadhi Aparicio-Siegmund, Christoph Garbers
Sci Rep. 2020; 10: 21612. Published online 2020 Dec 10. doi: 10.1038/s41598-020-77884-4
PMCID:
PMC7730449
AbstractArticlePDF–4.0M
13.
Spatially and temporally defined lysosomal leakage facilitates mitotic chromosome segregation
Saara Hämälistö, Jonathan Lucien Stahl, Elena Favaro, Qing Yang, Bin Liu, Line Christoffersen, Ben Loos, Claudia Guasch Boldú, Johanna A. Joyce, Thomas Reinheckel, Marin Barisic, Marja Jäättelä
Nat Commun. 2020; 11: 229. Published online 2020 Jan 13. doi: 10.1038/s41467-019-14009-0
PMCID:
PMC6957743
AbstractArticlePDF–4.3M
14.
Cathepsin S Deficiency Mitigated Chronic Stress–Related Neointimal Hyperplasia in Mice
Hailong Wang, Xiangkun Meng, Limei Piao, Aiko Inoue, Wenhu Xu, Chenglin Yu, Kae Nakamura, Lina Hu, Takeshi Sasaki, Hongxian Wu, Kazumasa Unno, Hiroyuki Umegaki, Toyoaki Murohara, Guo‐Ping Shi, Masafumi Kuzuya, Xian Wu Cheng
J Am Heart Assoc. 2019 Jul 16; 8(14): e011994. Published online 2019 Jul 12. doi: 10.1161/JAHA.119.011994
PMCID:
PMC6662117
AbstractArticlePDF–5.6M
15.
Peripheral Role of Cathepsin S in Th1 Cell-Dependent Transition of Nerve Injury-Induced Acute Pain to a Chronic Pain State
Xinwen Zhang, Zhou Wu, Yoshinori Hayashi, Ryo Okada, Hiroshi Nakanishi
J Neurosci. 2014 Feb 19; 34(8): 3013–3022. doi: 10.1523/JNEUROSCI.3681-13.2014
PMCID:
PMC6608526
AbstractArticlePDF–2.8M
16.
Frontline Science: Multiple cathepsins promote inflammasome‐independent, particle‐induced cell death during NLRP3‐dependent IL‐1β activation
Gregory M. Orlowski, Shruti Sharma, Jeff D. Colbert, Matthew Bogyo, Stephanie A. Robertson, Hiroshi Kataoka, Francis K. Chan, Kenneth L. Rock
J Leukoc Biol. 2017 Jul; 102(1): 7–17. Published online 2017 Jan 13. doi: 10.1189/jlb.3HI0316-152R
PMCID:
PMC6608057
AbstractArticle
17.
Cathepsin S regulates renal fibrosis in mouse models of mild and severe hydronephrosis
Xiaobing Yao, Fan Cheng, Weiming Yu, Ting Rao, Wei Li, Sheng Zhao, Xiangjun Zhou, Jinzhuo Ning
Mol Med Rep. 2019 Jul; 20(1): 141–150. Published online 2019 May 9. doi: 10.3892/mmr.2019.10230
PMCID:
PMC6580002
AbstractArticlePDF–1004K
18.
Longitudinal Analysis of Tear Cathepsin S Activity Levels in Male Non-Obese Diabetic Mice Suggests its Potential as an Early Stage Biomarker of Sjögren’s Syndrome
Srikanth R. Janga, Mihir Shah, Yaping Ju, Zhen Meng, Maria Edman, Sarah F. Hamm-Alvarez
Biomarkers. Author manuscript; available in PMC 2020 Feb 1.
Published in final edited form as: Biomarkers. 2019 Feb; 24(1): 91–102. Published online 2018 Sep 12. doi: 10.1080/1354750X.2018.1514656
PMCID:
PMC6414277
AbstractArticlePDF–1.3M
19.
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis
Paul K. Ziegler, Julia Bollrath, Charles K. Pallangyo, Takaji Matsutani, Özge Canli, Tiago De Oliveira, Michaela A. Diamanti, Nina Müller, Jaba Gamrekelashvili, Tracy Putoczki, David Horst, Arun K. Mankan, Meryem G. Öner, Susanna Müller, Josef Müller-Höcker, Thomas Kirchner, Julia Slotta-Huspenina, M. Mark Taketo, Thomas Reinheckel, Stefan Dröse, Andrew C. Larner, Winfried S. Wels, Matthias Ernst, Tim F. Greten, Melek C. Arkan, Thomas Korn, Dagmar Wirth, Florian R. Greten
Cell. Author manuscript; available in PMC 2019 Jun 28.
Published in final edited form as: Cell. 2018 Jun 28; 174(1): 88–101.e16. Published online 2018 Jun 14. doi: 10.1016/j.cell.2018.05.028
PMCID:
PMC6354256
AbstractArticlePDF–3.4M
20.
Single-cell transcriptomic analysis of mouse neocortical development
Lipin Loo, Jeremy M. Simon, Lei Xing, Eric S. McCoy, Jesse K. Niehaus, Jiami Guo, E. S. Anton, Mark J. Zylka
Nat Commun. 2019; 10: 134. Published online 2019 Jan 11. doi: 10.1038/s41467-018-08079-9
PMCID:
PMC6329831
AbstractArticlePDF–3.6M

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