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Select item 114923211.

Gene expression and characterization of clonally derived murine embryonic brown and brite adipocytes

Cristina Velez‐delValle, Claudia Patricia Hernandez‐Mosqueira, Lidia Itzel Castro‐Rodriguez, Alfredo Vazquez‐Sandoval, Meytha Marsch‐Moreno, Walid Kuri‐Harcuch

FEBS Open Bio. 2024 Sep; 14(9): 1503–1525. Published online 2024 Jul 7. doi: 10.1002/2211-5463.13861

PMCID:: PMC11492321

Abstract Article PDF–3.6M

Select item 114526232.

The G4 resolvase Dhx36 modulates cardiomyocyte differentiation and ventricular conduction system development

Pablo Gómez-del Arco, Joan Isern, Daniel Jimenez-Carretero, Dolores López-Maderuelo, Rebeca Piñeiro-Sabarís, Fadoua El Abdellaoui-Soussi, Carlos Torroja, María Linarejos Vera-Pedrosa, Mercedes Grima-Terrén, Alberto Benguria, Ana Simón-Chica, Antonio Queiro-Palou, Ana Dopazo, Fátima Sánchez-Cabo, José Jalife, José Luis de la Pompa, David Filgueiras-Rama, Pura Muñoz-Cánoves, Juan Miguel Redondo

Nat Commun. 2024; 15: 8602. Published online 2024 Oct 4. doi: 10.1038/s41467-024-52809-1

PMCID:: PMC11452623

Abstract Article PDF–4.1M

Select item 113203463.

Aging‐associated decrease of PGC‐1α promotes pain chronification

Xinbo Wu, Liuyue Yang, Zihua Li, Chenzheng Gu, Kaiyan Jin, Andrew Luo, Nabeel Faiyaz Rasheed, Isabella Fiutak, Kristina Chao, Amy Chen, Jianren Mao, Qian Chen, Weihua Ding, Shiqian Shen

Aging Cell. 2024 Aug; 23(8): e14177. Published online 2024 May 17. doi: 10.1111/acel.14177

PMCID:: PMC11320346

Abstract Article PDF–4.0M

Select item 112666554.

Intrauterine hyperglycaemia during late gestation caused mitochondrial dysfunction in skeletal muscle of male offspring through CREB/PGC1A signaling

Yi-Shang Yan, Jia-Ying Mo, Yu-Tong Huang, Hong Zhu, Hai-Yan Wu, Zhong-Liang Lin, Rui Liu, Xuan-Qi Liu, Ping-Ping Lv, Chun Feng, Jian-Zhong Sheng, Min Jin, He-Feng Huang

Nutr Diabetes. 2024; 14: 56. Published online 2024 Jul 23. doi: 10.1038/s41387-024-00299-x

PMCID:: PMC11266655

Abstract Article PDF–5.5M

Select item 112541805.

Adaptive gene expression of alternative splicing variants of PGC-1α regulates whole-body energy metabolism

Kazuhiro Nomura, Shinichi Kinoshita, Nao Mizusaki, Yoko Senga, Tsutomu Sasaki, Tadahiro Kitamura, Hiroshi Sakaue, Aki Emi, Tetsuya Hosooka, Masahiro Matsuo, Hitoshi Okamura, Taku Amo, Alexander M. Wolf, Naomi Kamimura, Shigeo Ohta, Tomoo Itoh, Yoshitake Hayashi, Hiroshi Kiyonari, Anna Krook, Juleen R. Zierath, Masato Kasuga, Wataru Ogawa

Mol Metab. 2024 Aug; 86: 101968. Published online 2024 Jun 15. doi: 10.1016/j.molmet.2024.101968

PMCID:: PMC11254180

Abstract Article PDF–4.4M

Select item 111442686.

PGC-1α repression dysregulates lipid metabolism and induces lipid droplet accumulation in the retinal pigment epithelium

Shuyan Zhou, Kaan Taskintuna, Jacob Hum, Jasmine Gulati, Stephanie Olaya, Jeremy Steinman, Nady Golestaneh

Cell Death Dis. 2024 Jun; 15(6): 385. Published online 2024 Jun 1. doi: 10.1038/s41419-024-06762-y

PMCID:: PMC11144268

Abstract Article PDF–13M

Select item 111427387.

Intermittent glucocorticoid treatment improves muscle metabolism via the PGC1α/Lipin1 axis in an aging-related sarcopenia model

Ashok D. Prabakaran, Kevin McFarland, Karen Miz, Hima Bindu Durumutla, Kevin Piczer, Fadoua El Abdellaoui Soussi, Hannah Latimer, Cole Werbrich, Hyun-Jy Chung, N. Scott Blair, Douglas P. Millay, Andrew J. Morris, Brendan Prideaux, Brian N. Finck, Mattia Quattrocelli

J Clin Invest. 2024 Jun 3; 134(11): e177427. Published online 2024 May 3. doi: 10.1172/JCI177427

PMCID:: PMC11142738

Abstract Article PDF–5.6M

Select item 111148588.

Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson’s disease

Giuseppa Mudò, Johanna Mäkelä, Valentina Di Liberto, Timofey V. Tselykh, Melania Olivieri, Petteri Piepponen, Ove Eriksson, Annika Mälkiä, Alessandra Bonomo, Minna Kairisalo, Jose A. Aguirre, Laura Korhonen, Natale Belluardo, Dan Lindholm

Cell Mol Life Sci. 2012 Apr; 69(7): 1153–1165. Published online 2011 Oct 8. doi: 10.1007/s00018-011-0850-z

PMCID:: PMC11114858

Abstract Article PDF–745K

Select item 111055539.

PGC-1α induced browning promotes involution and inhibits lactation in mammary glands

Elena Piccinin, Annalisa Morgano, Claudia Peres, Annalisa Contursi, Justine Bertrand-Michel, Maria Arconzo, Hervé Guillou, Gaetano Villani, Antonio Moschetta

Cell Mol Life Sci. 2019 Dec; 76(24): 5011–5025. Published online 2019 Jun 1. doi: 10.1007/s00018-019-03160-y

PMCID:: PMC11105553

Abstract Article PDF–8.3M

Select item 1107401310.

PGC-1α activation boosts exercise-dependent cellular response in the skeletal muscle

Soroosh Mozaffaritabar, Erika Koltai, Lei Zhou, Zoltan Bori, Attila Kolonics, Sylwester Kujach, Yaodong Gu, Atsuko Koike, Anita Boros, Zsolt Radák

J Physiol Biochem. 2024; 80(2): 329–335. Published online 2024 Jan 23. doi: 10.1007/s13105-024-01006-1

PMCID:: PMC11074013

Abstract Article PDF–872K

Select item 1095356511.

Cfp1 Controls Cardiomyocyte Maturation by Modifying Histone H3K4me3 of Structural, Metabolic, and Contractile Related Genes

Changzhu Li, Yang Zhang, Jingling Shen, Hairong Bao, Yue Zhao, Desheng Li, Sijia Li, Yining Liu, Jiming Yang, Zhiwen Zhou, Kangyi Gao, Lexin Zhao, Yao Pei, Yanjie Lu, Zhenwei Pan, Benzhi Cai

Adv Sci (Weinh) 2024 Mar; 11(11): 2305992. Published online 2024 Jan 9. doi: 10.1002/advs.202305992

PMCID:: PMC10953565

Abstract Article PDF–5.8M

Select item 1091766012.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 1090449313.

Skeletal muscle TET3 promotes insulin resistance through destabilisation of PGC-1α

Beibei Liu, Di Xie, Xinmei Huang, Sungho Jin, Yangyang Dai, Xiaoli Sun, Da Li, Anton M. Bennett, Sabrina Diano, Yingqun Huang

Diabetologia. 2024; 67(4): 724–737. Published online 2024 Jan 13. doi: 10.1007/s00125-023-06073-5

PMCID:: PMC10904493

Abstract Article PDF–1.4M

Select item 1087327414.

Exercise enhances placental labyrinth trophoblast development by activation of PGC-1α and FNDC5/irisin

Song Ah Chae, Min Du, Mei-Jun Zhu, Jun Seok Son

Biol Reprod. 2024 Feb; 110(2): 355–364. Published online 2023 Nov 2. doi: 10.1093/biolre/ioad151

PMCID:: PMC10873274

Abstract Article PDF–1.7M

Select item 1086642815.

An enriched environment ameliorates maternal sleep deprivation-induced cognitive impairment in aged mice by improving mitochondrial function via the Sirt1/PGC-1α pathway

Ru-Meng Wei, Yue-Ming Zhang, Kai-Xuan Zhang, Gao-Xia Liu, Xue-Yan Li, Jing-Ya Zhang, Wei-Zhong Lun, Xue-Chun Liu, Gui-Hai Chen

Aging (Albany NY) 2024 Jan 31; 16(2): 1128–1144. Published online 2024 Jan 16. doi: 10.18632/aging.205385

PMCID:: PMC10866428

Abstract Article PDF–2.1M

Select item 1086598216.

Bicuculline Restores Frequency-Dependent Hippocampal I/E Ratio and Circuit Function in PGC-1ɑ Null Mice

Dwipayan Bhattacharya, Aundrea F. Bartley, Qin Li, Lynn E. Dobrunz

Neurosci Res. Author manuscript; available in PMC 2024 Feb 14.

Published in final edited form as: Neurosci Res. 2022 Nov; 184: 9–18. Published online 2022 Jul 14. doi: 10.1016/j.neures.2022.07.003

PMCID:: PMC10865982

Abstract Article PDF–1.9M

Select item 1079988017.

Peroxisome proliferator-activated receptor γ coactivator 1α regulates downstream of tyrosine kinase-7 (Dok-7) expression important for neuromuscular junction formation

Takumi Sugimoto, Chihiro Sakamaki, Tokushi Kimura, Takahiro Eguchi, Shinji Miura, Yasutomi Kamei

Sci Rep. 2024; 14: 1780. Published online 2024 Jan 20. doi: 10.1038/s41598-024-52198-x

PMCID:: PMC10799880

Abstract Article PDF–1.6M

Select item 1071786318.

Endurance exercise increases the protein levels of PGC-1α and respiratory chain complexes in mouse skeletal muscle during atorvastatin administration

Koji Nonaka, Yutaka Ozaki, Kenichi Ito, Masahiro Sakita, Satsuki Une, Junichi Akiyama

J Physiol Sci. 2019 Mar; 69(2): 327–333. Published online 2018 Dec 8. doi: 10.1007/s12576-018-0649-x

PMCID:: PMC10717863

Abstract Article PDF–1.0M

Select item 1071769419.

Chronic voluntary wheel running exercise ameliorates metabolic dysfunction via PGC-1α expression independently of FNDC5/irisin pathway in high fat diet-induced obese mice

Chaeeun Cho, Minje Ji, Eunhee Cho, Seon Yi, Jae Geun Kim, Sewon Lee

J Physiol Sci. 2023; 73: 6. Published online 2023 Apr 11. doi: 10.1186/s12576-023-00864-6

PMCID:: PMC10717694

Abstract Article PDF–1.6M

Select item 1059218720.

Ncoa2 promotes CD8⁺ T cell-mediated anti-tumor immunity by stimulating T-cell activation via upregulation of PGC-1α critical for mitochondrial function: Noca2 in CD8+ T-cell activation and antitumor response

Xiancai Zhong, Hongmin Wu, Ching Ouyang, Wencan Zhang, Yun Shi, Yi-Chang Wang, David K. Ann, Yousang Gwack, Weirong Shang, Zuoming Sun

Cancer Immunol Res. Author manuscript; available in PMC 2024 Apr 4.

Published in final edited form as: Cancer Immunol Res. 2023 Oct 4; 11(10): 1414–1431. doi: 10.1158/2326-6066.CIR-23-0092

PMCID:: PMC10592187

Abstract Article PDF–2.4M

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