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Items: 1 to 20 of 24

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Loss of ARC Worsens High Fat Diet-Induced Hyperglycemia in Mice
Andrew T. Templin, Christine Schmidt, Meghan F. Hogan, Nathalie Esser, Richard N. Kitsis, Rebecca L. Hull, Sakeneh Zraika, Steven E. Kahn
J Endocrinol. Author manuscript; available in PMC 2022 Sep 20.
Published in final edited form as: J Endocrinol. 2021 Sep 20; 251(2): 125–135. Published online 2021 Sep 20. doi: 10.1530/JOE-20-0612
PMCID:
PMC8651217
AbstractArticlePDF–1.0M
3.
Conversion of the death inhibitor ARC to a killer activates pancreatic β-cell death in diabetes
Wendy M. McKimpson, Yun Chen, James A. Irving, Min Zheng, Jeremy Weinberger, Wilson Lek Wen Tan, Zenia Tiang, Alistair M. Jagger, Streamson C. Chua, Jr., Jeffrey E. Pessin, Roger S.-Y. Foo, David A. Lomas, Richard N. Kitsis
Dev Cell. Author manuscript; available in PMC 2022 Mar 22.
Published in final edited form as: Dev Cell. 2021 Mar 22; 56(6): 747–760.e6. Published online 2021 Mar 4. doi: 10.1016/j.devcel.2021.02.011
PMCID:
PMC8146085
AbstractArticlePDF–2.9M
4.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
5.
MS/MS in silico subtraction-based proteomic profiling as an approach to facilitate disease gene discovery: application to lens development and cataract
Sandeep Aryal, Deepti Anand, Francisco G. Hernandez, Bailey A. T. Weatherbee, Hongzhan Huang, Ashok P. Reddy, Phillip A. Wilmarth, Larry L. David, Salil A. Lachke
Hum Genet. Author manuscript; available in PMC 2021 Feb 1.
Published in final edited form as: Hum Genet. 2020 Feb; 139(2): 151–184. Published online 2019 Dec 3. doi: 10.1007/s00439-019-02095-5
PMCID:
PMC6983357
AbstractArticlePDF–3.8M
6.
ARC regulates programmed necrosis and myocardial ischemia/reperfusion injury through the inhibition of mPTP opening
Tao Xu, Wei Ding, Xiang Ao, Xianming Chu, Qinggong Wan, Yu Wang, Dandan Xiao, Wanpeng Yu, Mengyang Li, Fei Yu, Jianxun Wang
Redox Biol. 2019 Jan; 20: 414–426. Published online 2018 Nov 2. doi: 10.1016/j.redox.2018.10.023
PMCID:
PMC6230922
AbstractArticlePDF–3.3M
7.
ARC is essential for maintaining pancreatic islet structure and β-cell viability during type 2 diabetes
Wendy M. McKimpson, Min Zheng, Streamson C. Chua, Jeffrey E. Pessin, Richard N. Kitsis
Sci Rep. 2017; 7: 7019. Published online 2017 Aug 1. doi: 10.1038/s41598-017-07107-w
PMCID:
PMC5539143
AbstractArticlePDF–1.6M
8.
Inhibition of ARC decreases the survival of HEI-OC-1 cells after neomycin damage in vitro
Ming Guan, Qiaojun Fang, Zuhong He, Yong Li, Fuping Qian, Xiaoyun Qian, Ling Lu, Xiaoli Zhang, Dingding Liu, Jieyu Qi, Shasha Zhang, Mingliang Tang, Xia Gao, Renjie Chai
Oncotarget. 2016 Oct 11; 7(41): 66647–66659. Published online 2016 Aug 20. doi: 10.18632/oncotarget.11336
PMCID:
PMC5341827
AbstractArticlePDF–10M
9.
A myeloid tumor suppressor role for NOL3
Robert F. Stanley, Richard T. Piszczatowski, Boris Bartholdy, Kelly Mitchell, Wendy M. McKimpson, Swathi Narayanagari, Dagmar Walter, Tihomira I. Todorova, Cassandra Hirsch, Hideki Makishima, Britta Will, Christine McMahon, Kira Gritsman, Jaroslaw P. Maciejewski, Richard N. Kitsis, Ulrich Steidl
J Exp Med. 2017 Mar 6; 214(3): 753–771. doi: 10.1084/jem.20162089
PMCID:
PMC5339683
AbstractArticlePDF–3.5M
10.
The Cell Death Inhibitor ARC Is Induced in a Tissue-Specific Manner by Deletion of the Tumor Suppressor Gene Men1, but Not Required for Tumor Development and Growth
Wendy M. McKimpson, Ziqiang Yuan, Min Zheng, Judy S. Crabtree, Steven K. Libutti, Richard N. Kitsis
PLoS One. 2015; 10(12): e0145792. Published online 2015 Dec 28. doi: 10.1371/journal.pone.0145792
PMCID:
PMC4692498
AbstractArticlePDF–1.0M
11.
A Critical Role for the Anti-apoptotic Protein ARC (Apoptosis Repressor with CARD) in Hypoxia-Induced Pulmonary Hypertension
Ari L Zaiman, Rachel Damico, Alan Thoms-Chesley, D Clark Files, Priya Kesari, Laura Johnston, Mara Swaim, Shehzin Mozammel, Alan C Myers, Marc Halushka, Hasim El-Haddad, Larissa A Shimoda, Chang-Fu Peng, Paul M Hassoun, Hunter C Champion, Richard N Kitsis, Michael T Crow
Circulation. Author manuscript; available in PMC 2015 Sep 25.
Published in final edited form as: Circulation. 2011 Dec 6; 124(23): 2533–2542. Published online 2011 Nov 14. doi: 10.1161/CIRCULATIONAHA.111.034512
PMCID:
PMC4583146
AbstractArticlePDF–2.5M
12.
A genomic atlas of mouse hypothalamic development
Tomomi Shimogori, Daniel A Lee, Ana Miranda-Angulo, Yanqin Yang, Hong Wang, Lizhi Jiang, Aya C Yoshida, Ayane Kataoka, Hiromi Mashiko, Marina Avetisyan, Lixin Qi, Jiang Qian, Seth Blackshaw
Nat Neurosci. Author manuscript; available in PMC 2014 Jun 24.
Published in final edited form as: Nat Neurosci. 2010 Jun; 13(6): 767–775. Published online 2010 May 2. doi: 10.1038/nn.2545
PMCID:
PMC4067769
AbstractArticlePDF–1.8M
13.
Autophagic program is regulated by miR-325
L Bo, D Su-Ling, L Fang, Z Lu-Yu, A Tao, D Stefan, W Kun, L Pei-Feng
Cell Death Differ. 2014 Jun; 21(6): 967–977. Published online 2014 Feb 14. doi: 10.1038/cdd.2014.18
PMCID:
PMC4013515
AbstractArticlePDF–1.4M
14.
A novel role for the apoptosis inhibitor ARC in suppressing TNFα-induced regulated necrosis
G Kung, P Dai, L Deng, R N Kitsis
Cell Death Differ. 2014 Apr; 21(4): 634–644. Published online 2014 Jan 17. doi: 10.1038/cdd.2013.195
PMCID:
PMC3950326
AbstractArticlePDF–2.6M
15.
Apoptosis Repressor with a CARD Domain (ARC) Restrains Bax-Mediated Pathogenesis in Dystrophic Skeletal Muscle
Jennifer Davis, Jennifer Q. Kwong, Richard N. Kitsis, Jeffery D. Molkentin
PLoS One. 2013; 8(12): e82053. Published online 2013 Dec 2. doi: 10.1371/journal.pone.0082053
PMCID:
PMC3846897
AbstractArticlePDF–3.5M
16.
The Apoptosis Inhibitor ARC Alleviates the ER Stress Response to Promote β-Cell Survival
Wendy M. McKimpson, Jeremy Weinberger, Lech Czerski, Min Zheng, Michael T. Crow, Jeffrey E. Pessin, Streamson C. Chua, Jr., Richard N. Kitsis
Diabetes. 2013 Jan; 62(1): 183–193. Published online 2012 Dec 13. doi: 10.2337/db12-0504
PMCID:
PMC3526036
AbstractArticlePDF–2.5M
17.
Apoptosis inhibitor ARC promotes breast tumorigenesis, metastasis and chemoresistance
Christina M. Medina-Ramirez, Sumanta Goswami, Tatiana Smirnova, Daniel Bamira, Benjamin Benson, Neal Ferrick, Jeffrey Segall, Jeffrey W. Pollard, Richard N. Kitsis
Cancer Res. Author manuscript; available in PMC 2012 Dec 15.
Published in final edited form as: Cancer Res. 2011 Dec 15; 71(24): 7705–7715. Published online 2011 Oct 28. doi: 10.1158/0008-5472.CAN-11-2192
PMCID:
PMC3245742
AbstractArticlePDF–2.6M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Protection of Cardiomyocytes from Ischemic/Hypoxic Cell Death via Drbp1 and pMe2GlyDH in Cardio-specific ARC Transgenic Mice
Jong-Ok Pyo, Jihoon Nah, Hyo-Jin Kim, Jae-Woong Chang, Young-Wha Song, Dong-Kwon Yang, Dong-Gyu Jo, Hyung-Ryong Kim, Han-Jung Chae, Soo-Wan Chae, Seung-Yong Hwang, Seung-Jun Kim, Hyo-Joon Kim, Chunghee Cho, Chang-Gyu Oh, Woo Jin Park, Yong-Keun Jung
J Biol Chem. 2008 Nov 7; 283(45): 30707–30714. doi: 10.1074/jbc.M804209200
PMCID:
PMC2662156
AbstractArticlePDF–486K
20.
Comparative Analysis of Apoptosis and Inflammation Genes of Mice and Humans
John C. Reed, Kutbuddin Doctor, Ana Rojas, Juan M. Zapata, Christian Stehlik, Loredana Fiorentino, Jason Damiano, Wilfried Roth, Shu-ichi Matsuzawa, Ruchi Newman, Shinichi Takayama, Hiroyuki Marusawa, Famming Xu, Guy Salvesen, RIKEN GER Group, GSL Members, Adam Godzik
Genome Res. 2003 Jun; 13(6b): 1376–1388. doi: 10.1101/gr.1053803
PMCID:
PMC403667
AbstractArticlePDF–157K

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