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Items: 1 to 20 of 36

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
The Mechanism of NEDD8 Activation of CUL5 Ubiquitin E3 Ligases
Ryan J. Lumpkin, Alla S. Ahmad, Rachel Blake, Christopher J. Condon, Elizabeth A. Komives
Mol Cell Proteomics. 2021; 20: 100019. Published online 2021 Jan 6. doi: 10.1074/mcp.RA120.002414
PMCID:
PMC7950132
AbstractArticlePDF–3.1M
3.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
4.
CRL5-dependent regulation of the small GTPases ARL4C and ARF6 controls hippocampal morphogenesis
Jisoo S. Han, Keiko Hino, Wenzhe Li, Raenier V. Reyes, Cesar P. Canales, Adam M. Miltner, Yasmin Haddadi, Junqing Sun, Chao-Yin Chen, Anna La Torre, Sergi Simó
Proc Natl Acad Sci U S A. 2020 Sep 15; 117(37): 23073–23084. Published online 2020 Sep 1. doi: 10.1073/pnas.2002749117
PMCID:
PMC7502717
AbstractArticlePDF–3.3M
5.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
6.
Comparative Analysis of cul5 and rbx2 Expression in the Developing and Adult Murine Brain and Their Essentiality During Mouse Embryogenesis
Keiko Hino, Sergi Simó, Jonathan A. Cooper
Dev Dyn. Author manuscript; available in PMC 2019 Nov 7.
Published in final edited form as: Dev Dyn. 2018 Nov; 247(11): 1227–1236. Published online 2018 Nov 7. doi: 10.1002/dvdy.24675
PMCID:
PMC6639038
AbstractArticlePDF–3.0M
7.
SAG/RBX2 E3 Ubiquitin Ligase Differentially Regulates Inflammatory Responses of Myeloid Cell Subsets
Xiufang Xiong, Nathan D. Mathewson, Hua Li, Mingjia Tan, Hideaki Fujiwara, Haomin Li, Pavan Reddy, Yi Sun
Front Immunol. 2018; 9: 2882. Published online 2018 Dec 6. doi: 10.3389/fimmu.2018.02882
PMCID:
PMC6291737
AbstractArticlePDF–1.5M
8.
RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion
Corinne L. Fairchild, Keiko Hino, Jisoo S. Han, Adam M. Miltner, Gabriel Peinado Allina, Caileigh E. Brown, Marie E. Burns, Anna La Torre, Sergi Simó
Development. 2018 Feb 1; 145(3): dev155283. doi: 10.1242/dev.155283
PMCID:
PMC5817999
AbstractArticle
9.
SAG/Rbx2-Dependent Neddylation Regulates T-Cell Responses
Nathan D. Mathewson, Hideaki Fujiwara, Shin-Rong Wu, Tomomi Toubai, Katherine Oravecz-Wilson, Yaping Sun, Corinne Rossi, Cynthia Zajac, Yi Sun, Pavan Reddy
Am J Pathol. 2016 Oct; 186(10): 2679–2691. doi: 10.1016/j.ajpath.2016.06.014
PMCID:
PMC5222982
AbstractArticlePDF–2.7M
10.
Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury
Yong Wu, Fan-Yan Wei, Layla Kawarada, Takeo Suzuki, Kimi Araki, Yoshihiro Komohara, Atsushi Fujimura, Taku Kaitsuka, Motohiro Takeya, Yuichi Oike, Tsutomu Suzuki, Kazuhito Tomizawa
PLoS Genet. 2016 Sep; 12(9): e1006355. Published online 2016 Sep 30. doi: 10.1371/journal.pgen.1006355
PMCID:
PMC5045200
AbstractArticlePDF–2.9M
11.
Erbin is a novel substrate of the Sag-βTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis
Chuan-Ming Xie, Dongping Wei, Lili Zhao, Sylvie Marchetto, Lin Mei, Jean-Paul Borg, Yi Sun
J Cell Biol. 2015 Jun 8; 209(5): 721–738. doi: 10.1083/jcb.201411104
PMCID:
PMC4460146
AbstractArticlePDF–3.6M
12.
Inactivation of Sag/Rbx2/Roc2 E3 Ubiquitin Ligase Triggers Senescence and Inhibits Kras-Induced Immortalization
Mingjia Tan, Hua Li, Yi Sun
Neoplasia. 2015 Jan; 17(1): 114–123. Published online 2015 Jan 23. doi: 10.1016/j.neo.2014.11.008
PMCID:
PMC4309684
AbstractArticlePDF–1.8M
13.
Endothelial deletion of Sag/Rbx2/Roc2 E3 ubiquitin ligase causes embryonic lethality and blocks tumor angiogenesis
Mingjia Tan, Hua Li, Yi Sun
Oncogene. Author manuscript; available in PMC 2015 Apr 30.
Published in final edited form as: Oncogene. 2014 Oct 30; 33(44): 5211–5220. Published online 2013 Nov 11. doi: 10.1038/onc.2013.473
PMCID:
PMC4016996
AbstractArticlePDF–1.2M
14.
Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line
J M Cheverud, H A Lawson, K Bouckaert, A V Kossenkov, L C Showe, L Cort, E P Blankenhorn, K Bedelbaeva, D Gourevitch, Y Zhang, E Heber-Katz
Heredity (Edinb) 2014 May; 112(5): 508–518. Published online 2014 Feb 26. doi: 10.1038/hdy.2013.133
PMCID:
PMC3998788
AbstractArticlePDF–1.8M
15.
Inactivation of SAG/RBX2 E3 ubiquitin ligase suppresses KrasG12D-driven lung tumorigenesis
Hua Li, Mingjia Tan, Lijun Jia, Dongping Wei, Yongchao Zhao, Guoan Chen, Jie Xu, Lili Zhao, Dafydd Thomas, David G. Beer, Yi Sun
J Clin Invest. 2014 Feb 3; 124(2): 835–846. Published online 2014 Jan 16. doi: 10.1172/JCI70297
PMCID:
PMC3904615
AbstractArticlePDF–4.9M
16.
Rbx2 regulates neuronal migration through different Cullin5-RING ligase adaptors
Sergi Simó, Jonathan A. Cooper
Dev Cell. Author manuscript; available in PMC 2014 Nov 25.
Published in final edited form as: Dev Cell. 2013 Nov 25; 27(4): 10.1016/j.devcel.2013.09.022. Published online 2013 Nov 7. doi: 10.1016/j.devcel.2013.09.022
PMCID:
PMC3851519
AbstractArticlePDF–6.4M
17.
Suppressor of Cytokine Signaling (SOCS) 5 Utilises Distinct Domains for Regulation of JAK1 and Interaction with the Adaptor Protein Shc-1
Edmond M. Linossi, Indu R. Chandrashekaran, Tatiana B. Kolesnik, James M. Murphy, Andrew I. Webb, Tracy A. Willson, Lukasz Kedzierski, Alex N. Bullock, Jeffrey J. Babon, Raymond S. Norton, Nicos A. Nicola, Sandra E. Nicholson
PLoS One. 2013; 8(8): e70536. Published online 2013 Aug 21. doi: 10.1371/journal.pone.0070536
PMCID:
PMC3749136
AbstractArticlePDF–3.3M
18.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
19.
The Glomuvenous Malformation Protein Glomulin Binds Rbx1 and Regulates Cullin RING Ligase-Mediated Turnover of Fbw7
Adriana E. Tron, Takehiro Arai, David M. Duda, Hiroshi Kuwabara, Jennifer L. Olszewski, Yuko Fujiwara, Brittany N. Bahamon, Sabina Signoretti, Brenda A. Schulman, James A. DeCaprio
Mol Cell. Author manuscript; available in PMC 2012 Oct 13.
Published in final edited form as: Mol Cell. 2012 Apr 13; 46(1): 67–78. Published online 2012 Mar 8. doi: 10.1016/j.molcel.2012.02.005
PMCID:
PMC3336104
AbstractArticlePDF–3.4M
20.
SAG/RBX2/ROC2 E3 ubiquitin ligase is essential for vascular and neural development by targeting NF1 for degradation
Mingjia Tan, Yongchao Zhao, Sun-Jung Kim, Margaret Liu, Lijun Jia, Thomas L. Saunders, Yuan Zhu, Yi Sun
Dev Cell. Author manuscript; available in PMC 2012 Dec 13.
Published in final edited form as: Dev Cell. 2011 Dec 13; 21(6): 1062–1076. Published online 2011 Nov 23. doi: 10.1016/j.devcel.2011.09.014
PMCID:
PMC3241850
AbstractArticlePDF–3.7M

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