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Select item 113010681.

Decline in corepressor CNOT1 in the pregnant myometrium near term impairs progesterone receptor function and increases contractile gene expression

Youn-Tae Kwak, Alina P. Montalbano, Andrew M. Kelleher, Mariano Colon-Caraballo, W. Lee Kraus, Mala Mahendroo, Carole R. Mendelson

J Biol Chem. 2024 Jul; 300(7): 107484. Published online 2024 Jun 18. doi: 10.1016/j.jbc.2024.107484

PMCID:: PMC11301068

Abstract Article PDF–1.4M

Select item 111409072.

Knockout mice with pituitary malformations help identify human cases of hypopituitarism

Julian Martinez-Mayer, Michelle L. Brinkmeier, Sean P. O’Connell, Arnold Ukagwu, Marcelo A. Marti, Mirta Miras, Maria V. Forclaz, Maria G. Benzrihen, Leonard Y. M. Cheung, Sally A. Camper, Buffy S. Ellsworth, Lori T. Raetzman, Maria I. Pérez-Millán, Shannon W. Davis

Genome Med. 2024; 16: 75. Published online 2024 May 31. doi: 10.1186/s13073-024-01347-y

PMCID:: PMC11140907

Abstract Article PDF–4.4M

Select item 90902973.

CNOT1 regulates circadian behaviour through Per2 mRNA decay in a deadenylation-dependent manner

Haytham Mohamed Aly Mohamed, Akinori Takahashi, Saori Nishijima, Shungo Adachi, Iori Murai, Hitoshi Okamura, Tadashi Yamamoto

RNA Biol. 2022; 19(1): 703–718. Published online 2022 May 5. doi: 10.1080/15476286.2022.2071026

PMCID:: PMC9090297

Abstract Article PDF–3.4M

Select item 87633174.

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation

Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley

Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h

PMCID:: PMC8763317

Abstract Article

Select item 79387705.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 71193706.

The CCR4–NOT complex maintains liver homeostasis through mRNA deadenylation

Akinori Takahashi, Toru Suzuki, Shou Soeda, Shohei Takaoka, Shungo Kobori, Tomokazu Yamaguchi, Haytham Mohamed Aly Mohamed, Akiko Yanagiya, Takaya Abe, Mayo Shigeta, Yasuhide Furuta, Keiji Kuba, Tadashi Yamamoto

Life Sci Alliance. 2020 May; 3(5): e201900494. Published online 2020 Apr 1. doi: 10.26508/lsa.201900494

PMCID:: PMC7119370

Abstract Article PDF–6.4M

Select item 69996317.

Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability

Dina Mostafa, Akinori Takahashi, Akiko Yanagiya, Tomokazu Yamaguchi, Takaya Abe, Taku Kureha, Keiji Kuba, Yumi Kanegae, Yasuhide Furuta, Tadashi Yamamoto, Toru Suzuki

RNA Biol. 2020; 17(3): 403–416. Published online 2020 Jan 10. doi: 10.1080/15476286.2019.1709747

PMCID:: PMC6999631

Abstract Article PDF–6.3M

Select item 68622168.

The CCR4–NOT Deadenylase Complex Maintains Adipocyte Identity

Akinori Takahashi, Shohei Takaoka, Shungo Kobori, Tomokazu Yamaguchi, Sara Ferwati, Keiji Kuba, Tadashi Yamamoto, Toru Suzuki

Int J Mol Sci. 2019 Nov; 20(21): 5274. Published online 2019 Oct 24. doi: 10.3390/ijms20215274

PMCID:: PMC6862216

Abstract Article PDF–7.5M

Select item 66023009.

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules

Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer

J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252

PMCID:: PMC6602300

Abstract Article

Select item 650686710.

A CCR4-NOT Transcription Complex, Subunit 1, CNOT1, Variant Associated with Holoprosencephaly

Paul Kruszka, Seth I. Berger, Karin Weiss, Joshua L. Everson, Ariel F. Martinez, Sungkook Hong, Kwame Anyane-Yeboa, Robert J. Lipinski, Maximilian Muenke

Am J Hum Genet. 2019 May 2; 104(5): 990–993. Published online 2019 Apr 18. doi: 10.1016/j.ajhg.2019.03.017

PMCID:: PMC6506867

Abstract Article PDF–606K

Select item 650686211.

A Specific CNOT1 Mutation Results in a Novel Syndrome of Pancreatic Agenesis and Holoprosencephaly through Impaired Pancreatic and Neurological Development

Elisa De Franco, Rachel A. Watson, Wolfgang J. Weninger, Chi C. Wong, Sarah E. Flanagan, Richard Caswell, Angela Green, Catherine Tudor, Christopher J. Lelliott, Stefan H. Geyer, Barbara Maurer-Gesek, Lukas F. Reissig, Hana Lango Allen, Almuth Caliebe, Reiner Siebert, Paul Martin Holterhus, Asma Deeb, Fabrice Prin, Robert Hilbrands, Harry Heimberg, Sian Ellard, Andrew T. Hattersley, Inês Barroso

Am J Hum Genet. 2019 May 2; 104(5): 985–989. Published online 2019 Apr 18. doi: 10.1016/j.ajhg.2019.03.018

PMCID:: PMC6506862

Abstract Article PDF–1.2M

Select item 639844712.

Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes

Toru Suzuki, Chisato Kikuguchi, Saori Nishijima, Takeshi Nagashima, Akinori Takahashi, Mariko Okada, Tadashi Yamamoto

Development. 2019 Feb 15; 146(4): dev168146. Published online 2019 Feb 15. doi: 10.1242/dev.168146

PMCID:: PMC6398447

Abstract Article

Select item 624418313.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 586277114.

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies

David K. Breslow, Sascha Hoogendoorn, Adam R. Kopp, David W. Morgens, Brandon K. Vu, Margaret C. Kennedy, Kyuho Han, Amy Li, Gaelen T. Hess, Michael C. Bassik, James K. Chen, Maxence V. Nachury

Nat Genet. Author manuscript; available in PMC 2018 Aug 19.

Published in final edited form as: Nat Genet. 2018 Mar; 50(3): 460–471. Published online 2018 Feb 19. doi: 10.1038/s41588-018-0054-7

PMCID:: PMC5862771

Abstract Article PDF–2.5M

Select item 564508215.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594

PMCID:: PMC5645082

Abstract Article PDF–2.3M

Select item 538122616.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 524230317.

mTOR regulates the expression of DNA damage response enzymes in long‐lived Snell dwarf, GHRKO, and PAPPA‐KO mice

Graham Dominick, Jacqueline Bowman, Xinna Li, Richard A. Miller, Gonzalo G. Garcia

Aging Cell. 2017 Feb; 16(1): 52–60. Published online 2016 Sep 13. doi: 10.1111/acel.12525

PMCID:: PMC5242303

Abstract Article PDF–895K

Select item 472649718.

Post-transcriptional Control of Tumor Cell Autonomous Metastatic Potential by CCR4-NOT Deadenylase CNOT7

Farhoud Faraji, Ying Hu, Howard H. Yang, Maxwell P. Lee, G. Sebastian Winkler, Markus Hafner, Kent W. Hunter

PLoS Genet. 2016 Jan; 12(1): e1005820. Published online 2016 Jan 25. doi: 10.1371/journal.pgen.1005820

PMCID:: PMC4726497

Abstract Article PDF–3.7M

Select item 471841419.

Dead end1 is an essential partner of NANOS2 for selective binding of target RNAs in male germ cell development

Atsushi Suzuki, Yuki Niimi, Kaori Shinmyozu, Zhi Zhou, Makoto Kiso, Yumiko Saga

EMBO Rep. 2016 Jan; 17(1): 37–46. Published online 2015 Nov 20. doi: 10.15252/embr.201540828

PMCID:: PMC4718414

Abstract Article PDF–2.0M

Select item 415541920.

Identification of Ccr4-Not Complex Components as Regulators of Transition from Partial to Genuine Induced Pluripotent Stem Cells

Masayoshi Kamon, Miyuki Katano, Keiko Hiraki-Kamon, Tomoaki Hishida, Yutaka Nakachi, Yosuke Mizuno, Yasushi Okazaki, Ayumu Suzuki, Masataka Hirasaki, Atsushi Ueda, Masazumi Nishimoto, Hidemasa Kato, Akihiko Okuda

Stem Cells Dev. 2014 Sep 15; 23(18): 2170–2179. Published online 2013 Nov 8. doi: 10.1089/scd.2013.0326

PMCID:: PMC4155419

Abstract Article PDF–691K

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